Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications

Bibliography

• McNeil SE. Nanotechnology for the biologist. J Leukoc Biol 2005;78:585-94
   PubMed Web of Science ®Google Scholar
• Nel A, Xia T, Madler L, Li N. Toxic potential of materials at the nanolevel. Science 2006;311:622-7
   PubMed Web of Science ®Google Scholar
• Wagner V, Dullaart A, Bock AK, Zweck A. The emerging nanomedicine landscape. Nat Biotechnol 2006;24:1211-17
   PubMed Web of Science ®Google Scholar
• Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005;5:161-71
   PubMed Web of Science ®Google Scholar
• Panchal RG. Novel therapeutic strategies to selectively kill cancer cells. Biochem Pharmacol 1998;55:247-52
   PubMed Web of Science ®Google Scholar
• Roco MC. National Nanotechnology Initiative - Past, Present, Future. Handbook on Nanoscience, Engineering and Technology, 2nd edition. Taylor and Francis: New York, NY; 2007 (Preprint). Available from: www.nano.gov/html/res/articles.html [Last accessed 8 June 2010]
   Google Scholar
• Boyle P, Levin B. World Cancer Report 2008. International Agency for Research on Cancer World Health Organization; 2009. Available from: www.iarc.fr/en/publications/pdfs-online/wcr/ [Last accessed 8 June 2010]
   Google Scholar
• Nie S, Xing Y, Kim GJ, Simons JW. Nanotechnology applications in cancer. Annu Rev Biomed Eng 2007;9:257-88
   PubMed Web of Science ®Google Scholar
• Bosanquet AG, Bell PB. Ex vivo therapeutic index by drug sensitivity assay using fresh human normal and tumor cells. J Exp Ther Oncol 2004;4:145-54
   PubMedGoogle Scholar
• Hanley C, Layne J, Punnoose A, Preferential killing of cancer cells and activated human T cells using zinc oxide nanoparticles. Nanotechnology 2008;19:295103-13
   PubMed Web of Science ®Google Scholar
• Wang H, Wingett D, Engelhard MH, Fluorescent dye encapsulated ZnO particles with cell-specific toxicity for potential use in biomedical applications. J Mater Sci Mater Med 2009;20:11-22
   PubMed Web of Science ®Google Scholar
• Xia T, Kovochich M, Brant J, Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 2006;6:1794-807
   PubMed Web of Science ®Google Scholar
• Guo D, Wu C, Jiang H, Synergistic cytotoxic effect of different sized ZnO nanoparticles and daunorubicin against leukemia cancer cells under UV irradiation. J Photochem Photobiol B 2008;93:119-26
   PubMed Web of Science ®Google Scholar
• Kubota Y, Shuin T, Kawasaki C, Photokilling of T-24 human bladder cancer cells with titanium dioxide. Br J Cancer 1994;70:1107-11
   PubMed Web of Science ®Google Scholar
• Nair S, Sasidharan A, Divya Rani V, Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells. J Mater Sci Mater Med 2009;20:235-41
   PubMed Web of Science ®Google Scholar
• Zhang Y, Chen W, Wang SP, Phototoxicity of zinc oxide nanoparticle conjugates in human ovarian cancer. J Biomed Nanotechnol 2008;4:432-8
   Web of Science ®Google Scholar
• Brannon-Peppas L, Blanchette JO. Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev 2004;56:1649-59
   PubMed Web of Science ®Google Scholar
• Lanone S, Boczkowski J. Biomedical applications and potential health risks of nanomaterials: molecular mechanisms. Curr Mol Med 2006;6:651-63
   PubMed Web of Science ®Google Scholar
• Cho K, Wang X, Nie S, Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res 2008;14:1310-16
   PubMed Web of Science ®Google Scholar
• Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 2008;5:496-504
   PubMed Web of Science ®Google Scholar
• Ohgaki M, Kizuki T, Katsura M, Yamashita K. Manipulation of selective cell adhesion and growth by surface charges of electrically polarized hydroxyapatite. J Biomed Mater Res 2001;57:366-73
   PubMed Web of Science ®Google Scholar
• Leroueil PR, Hong S, Mecke A, Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face? Acc Chem Res 2007;40:335-42
   PubMed Web of Science ®Google Scholar
• Abercrombie M, Ambrose EJ. The surface properties of cancer cells: a review. Cancer Res 1962;22:525-48
   PubMed Web of Science ®Google Scholar
• Bockris JOM, Habib MA. Are there electrochemical aspects of cancer? J Biol Phys 1982;10:227-37
   Google Scholar
• Papo N, Shahar M, Eisenbach L, Shai Y. A novel lytic peptide composed of DL-amino acids selectively kills cancer cells in culture and in mice. J Biol Chem 2003;278:21018-23
   PubMed Web of Science ®Google Scholar
• Shrode LD, Tapper H, Grinstein S. Role of intracellular pH in proliferation, transformation, and apoptosis. J Bioenerg Biomembr 1997;29:393-99
   PubMed Web of Science ®Google Scholar
• Rich IN, Worthington-White D, Garden OA, Musk P. Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger. Blood 2000;95:1427-34
   PubMed Web of Science ®Google Scholar
• Tang YJ, Ashcroft JM, Chen D, Charge-associated effects of fullerene derivatives on microbial structural integrity and central metabolism. Nano Lett 2007;7:754-60
   PubMed Web of Science ®Google Scholar
• Xu P, Van Kirk EA, Zhan Y, Targeted charge-reversal nanoparticles for nuclear drug delivery. Angew Chem Int Ed Engl 2007;46:4999-5002
   PubMed Web of Science ®Google Scholar
• Wang RM, Xing YJ, and Yu DP. Fabrication and microstructure analysis on zinc oxide nanotubes. N J Phys 2003;5:115-17
   Google Scholar
• Wu HQ, Wei XW, Shao MW, Gu JS. Synthesis of zinc oxide nanorods using carbon nanotubes as templates. J Crystal Growth 2004;265:184-9
   Web of Science ®Google Scholar
• Nie L, Gao L, Feng P, Three-dimensional functionalized tetrapod-like ZnO nanostructures for plasmid DNA delivery. Small 2006;2:621-5
   PubMed Web of Science ®Google Scholar
• Hafeli UO, Riffle JS, Harris-Shekhawat L, Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery. Mol Pharm 2009;6:1417-28
   PubMed Web of Science ®Google Scholar
• Hagens WI, Oomen AG, de Jong WH, What do we (need to) know about the kinetic properties of nanoparticles in the body? Regul Toxicol Pharmacol 2007;49:217-29
   PubMed Web of Science ®Google Scholar
• Takenaka S, Karg E, Roth C, Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats. Environ Health Perspect 2001;109(Suppl 4):547-51
   PubMedGoogle Scholar
• Wang B, Feng W, Wang M, Acute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult mice. J Nanopart Res 2008;10:263-76
   Web of Science ®Google Scholar
• Sayes CM, Reed KL, Warheit DB. Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci 2007;97:163-80
   PubMed Web of Science ®Google Scholar
• Nohynek GJ, Dufour EK, Roberts MS. Nanotechnology, cosmetics and the skin: is there a health risk? Skin Pharmacol Physiol 2008;21:136-49
   PubMed Web of Science ®Google Scholar
• Zvyagin AV, Zhao X, Gierden A, Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo. J Biomed Opt 2008;13:064031-9
   PubMed Web of Science ®Google Scholar
• Carmody RJ, Cotter TG. Signaling apoptosis: a radical approach. Redox Rep 2001;6:77-90
   PubMed Web of Science ®Google Scholar
• Ryter SW, Kim HP, Hoetzel A, Mechanisms of cell death in oxidative stress. Antioxid Redox Signal 2007;9:49-89
   PubMed Web of Science ®Google Scholar
• Lin W, Xu Y, Huang CC, Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells. J Nanopart Res 2009;11:25-39
   Web of Science ®Google Scholar
• Jeng HA, Swanson J. Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health A Tox Hazard Subst Environ Eng 2006;41:2699-11
   PubMed Web of Science ®Google Scholar
• Mortimer M, Kasemets K, Kahru A. Toxicity of ZnO and CuO nanoparticles to ciliated protozoa Tetrahymena thermophila. Toxicology 2010;269:182-9
   PubMed Web of Science ®Google Scholar
• Franklin NM, Rogers NJ, Apte SC, Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): the importance of particle solubility. Environ Sci Technol 2007;41:8484-90
   PubMed Web of Science ®Google Scholar
• Kasemets K, Ivask A, Dubourguier HC, Kahru A. Toxicity of nanoparticles of ZnO, CuO and TiO2 to yeast Saccharomyces cerevisiae. Toxicol In Vitro 2009;23:1116-22
   PubMed Web of Science ®Google Scholar
• Zhu X, Zhu L, Duan Z, Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to Zebrafish (Danio rerio) early developmental stage. J Environ Sci Health A Tox Hazard Subst Environ Eng 2008;43:278-84
   PubMed Web of Science ®Google Scholar
• Deng X, Luan Q, Chen W, Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnology 2009;20:115101-6
   PubMed Web of Science ®Google Scholar
• Brunner TJ, Wick P, Manser P, In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol 2006;40:4374-81
   PubMed Web of Science ®Google Scholar
• Moos PJ, Chung K, Woessner D, ZnO particulate matter requires cell contact for toxicity in human colon cancer cells. Chem Res Toxicol 2010;23:733-9
   PubMed Web of Science ®Google Scholar
• Yang H, Liu C, Yang D, Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition. J Appl Toxicol 2009;29:69-78
   PubMed Web of Science ®Google Scholar
• Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr 1998;68:447S-63S
   PubMed Web of Science ®Google Scholar
• Truong-Tran AQ, Carter J, Ruffin R, Zalewski PD. New insights into the role of zinc in the respiratory epithelium. Immunol Cell Biol 2001;79:170-7
   PubMed Web of Science ®Google Scholar
• Lim NC, Freake HC, Bruckner C. Illuminating zinc in biological systems. Chemistry 2004;11:38-49
   PubMed Web of Science ®Google Scholar
• Choi DW, Koh JY. Zinc and brain injury. Annu Rev Neurosci 1998;21:347-75
   PubMed Web of Science ®Google Scholar
• Brasseur F, Couvreur P, Kante B, Actinomycin D absorbed on polymethylcyanoacrylate nanoparticles: increased efficiency against an experimental tumor. Eur J Cancer 1980;16:1441-5
   PubMed Web of Science ®Google Scholar
• Gregoriadis G, Neerunjun ED. Treatment of tumour bearing mice with liposome-entrapped actinomycin D prolongs their survival. Res Commun Chem Pathol Pharmacol 1975;10:351-62
   PubMedGoogle Scholar
• Mohamed F, van der Walle CF. Engineering biodegradable polyester particles with specific drug targeting and drug release properties. J Pharm Sci 2008;97:71-87
   PubMed Web of Science ®Google Scholar
• Hillebrenner H, Buyukserin F, Kang M, Corking nano test tubes by chemical self-assembly. J Am Chem Soc 2006;128:4236-7
   PubMed Web of Science ®Google Scholar
• Schillemans JP, van Nostrum CF. Molecularly imprinted polymer particles: synthetic receptors for future medicine. Nanomedicine 2006;1:437-47
   PubMed Web of Science ®Google Scholar
• Batist G, Barton J, Chaikin P, Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy. Expert Opin Pharmacother 2002;3:1739-51
   PubMedGoogle Scholar
• Cai R, Hashimoto K, Itoh Y, Photokilling of malignant cells with ultrafine titanium dioxide powder. Bull Chem Soc Jpn 1991;64:1268-73
   Web of Science ®Google Scholar
• Cai R, Kubota Y, Shuin T, Induction of cytotoxicity by photoexcited TiO2 particles. Cancer Res 1992;52:2346-8
   PubMed Web of Science ®Google Scholar
• Bakalova R, Ohba H, Zhelev Z, Quantum dots as photosensitizers? Nat Biotechnol 2004;22:1360-1
   PubMed Web of Science ®Google Scholar
• Jordan A, Scholz R, Maier-Hauff K, The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma. J Neurooncol 2006;78:7-14
   PubMed Web of Science ®Google Scholar
• Jordan A, Scholz R, Wust P, Magnetic fluid hyperthermia (MFH): Cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles. J Magnetism Magn Mater 1999;201:413-9
   Web of Science ®Google Scholar
• Nohynek GJ, Lademann J, Ribaud C, Roberts MS. Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety. Crit Rev Toxicol 2007;37:251-77
   PubMed Web of Science ®Google Scholar
• Applerot G, Lipovsky A, Dror R, Enhanced antibacterial activity of nanocrystalline ZnO due to increased ROS-mediated cell injury. Adv Funct Mater 2009;19:842-52
   Web of Science ®Google Scholar
• Colon G, Ward BC, and Webster TJ. Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res A 2006;78:595-604
   PubMedGoogle Scholar
• Dhobale S, Thite T, Laware SL, Zinc oxide nanoparticles as novel alpha-amylase inhibitors. J Appl Phys 2008;104:0949071-5S
   Google Scholar
• Yamaki K, Yoshino S. Comparison of inhibitory activities of zinc oxide ultrafine and fine particulates on IgE-induced mast cell activation. Biometals 2009;22:1031-40
   PubMed Web of Science ®Google Scholar
• Zhou J, Xu N, and Wang ZL. Dissolving behavior and stability of Zno wires in biofluids: a study on biodegradability and biocompatibility. Adv Mater 2006;18:2432-35
   Web of Science ®Google Scholar
• Hanley C, Thurber A, Hanna C, The influences of cell type and ZnO nanoparticle size and immune cell cytotoxicity and cytokine induction. Nanoscale Res Lett 2009;4:1409-20
   PubMed Web of Science ®Google Scholar
• Qu F, Morais PC. Energy levels in metal oxide semiconductor quantum dots in water-based colloids. J Chem Physics 1999;111:8588-94
   Web of Science ®Google Scholar
• Qu F, Morais PC. The pH dependence of the surface charge density in oxide-based semiconductor nanoparticles immersed in aqueous solution. IEEE Trans Magn 2001;37:2654-6
   Web of Science ®Google Scholar
• Degen A, Kosec M. Effect of pH and impurities on the surface charge of zinc oxide in aqueous solution. J Europena Ceramic Soc 2000;20:667-73
   Web of Science ®Google Scholar
• Nagao M. Physiosorption of water on zinc oxide surface. J Phys Chem 1971;75:3822-8
   Web of Science ®Google Scholar
• Grabarek Z, Gergely J. Zero-length crosslinking procedure with the use of active esters. Anal Biochem 1990;185:131-5
   PubMed Web of Science ®Google Scholar
• Horie M, Nishio K, Fujita K, Protein adsorption of ultrafine metal oxide and its influence on cytotoxicity toward cultured cells. Chem Res Toxicol 2009;22:543-53
   PubMed Web of Science ®Google Scholar
• Gorelikov I, Matsuura N. Single-step coating of mesoporous silica on cetyltrimethyl ammonium bromide-capped nanoparticles. Nano Lett 2008;8:369-73
   PubMed Web of Science ®Google Scholar
• Brayner R, Ferrari-Iliou R, Brivois N, Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett 2006;6:866-70
   PubMed Web of Science ®Google Scholar
• Long TC, Saleh N, Tilton RD, Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. Environ Sci Technol 2006;40:4346-52
   PubMed Web of Science ®Google Scholar
• Lovric J, Cho SJ, Winnik FM, Maysinger D. Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death. Chem Biol 2005;12:1227-34
   PubMed Web of Science ®Google Scholar
• Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles. Small 2008;4:26-49
   PubMed Web of Science ®Google Scholar
• Lany S, Osorio-Guillen J, Zunger A. Origins of the doping asymmetry in oxides: Hole doping in NiO versus electron doping in ZnO. Phys Rev B 2007;75:2412031-4
   Google Scholar
• Sharma SK, Pujari PK, Sudarshan K, Positron annihilation studies in ZnO nanoparticles. Solid State Commun 2009;149:550-4
   Web of Science ®Google Scholar
• Salem IA. Catalytic decomposition of hydrogen peroxide over supported ZnO. Monatshefte fur Chemie 2000;131:1139-50
   Web of Science ®Google Scholar
• Padmavathy N, Vijayaraghavan R. Enhanced bioactivity of ZnO nanoparticles - an antimicrobial study. Sci Technol Adv Mater 2008;9:1-7
   Web of Science ®Google Scholar
• Matsunaga T, Tomoda R, Nakajima T, Wake H. Photoelectrochemical sterilization of microbial cells by semiconductor powders. FEMS Microbiol Lett 1985;29:211-4
   Web of Science ®Google Scholar
• Kamat PV, Meisel D. Nanoscience opportunities in environmental remediation. C R Chimie 2003;6:999-1007
   Web of Science ®Google Scholar
• Hoffman AJ, Carraway ER, Hoffman M. Photocatalytic production of hydrogen peroxide and organic peroxides on quantum-sized semiconductor colloids. Environ Sci Technol 1994;28:776-85
   PubMed Web of Science ®Google Scholar
• Hays J, Reddy KM, Graces N, Effect of Co doping on the structural, optical and magnetic properties of ZnO. J Phys Condens Matter 2007;19:226203-26
   Google Scholar
• Sun L, Rippon JA, Cookson PG, Effects of undoped and manganese-doped zinc oxide nanoparticles on the colour fading of dyed polyester fabrics. Chem Eng J 2009;147:391-8
   Web of Science ®Google Scholar
• Pirkanniemi K, Sillanpaa M. Heterogeneous water phase catalysis as an environmental application: a review. Chemosphere 2002;48:1047-60
   PubMed Web of Science ®Google Scholar
• Choi W, Termin A, Hoffman MR. The role of metal-ion dopants in quantum-sized TiO2. J Phys Chem 1994;98:13669-79
   Web of Science ®Google Scholar
• Petit A, Mwale F, Tkaczyk C, Induction of protein oxidation by cobalt and chromium ions in human U937 macrophages. Biomaterials 2005;26:4416-22
   PubMed Web of Science ®Google Scholar
• George S, Pokhrel S, Xia T, Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano 2010;4:15-29
   PubMed Web of Science ®Google Scholar
• Reddy KM, Feris K, Bell J, Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systems. Appl Phys Lett 2007;90:213902-3
   Web of Science ®Google Scholar
• Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009;3:16-20
   PubMed Web of Science ®Google Scholar
• Yuan Q, Hein S, Misra RD. New generation of chitosan-encapsulated ZnO quantum dots loaded with drug: Synthesis, characterization and in vitro drug delivery response. Acta Biomater 2010;6:2732-9
   PubMed Web of Science ®Google Scholar
• Jain TK, Morales MA, Sahoo SK, Iron oxide nanoparticles for sustained delivery of anticancer agents. Mol Pharm 2005;2:194-205
   PubMed Web of Science ®Google Scholar
• Sun C, Fang C, Stepherr Z, Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles. Future Med 2008;3:495-505
   Google Scholar
• Patil S, Reshetnikov S, Haldar MK, Surface-derivatized nanoceria with human carbonic anhydrase II inhibitors and fluorophores: a potential drug delivery device. J Phys Chem C 2007;111:8437-42
   Web of Science ®Google Scholar
• Shen W, Xiong H, Xu Y, ZnO-poly(methyl methacrylate) nanobeads for enriching and desalting low-abundant proteins followed by directly MALDI-TOF MS analysis. Anal Chem 2008;80:6758-63
   PubMed Web of Science ®Google Scholar
• Dorfman A, Parajuli O, Kumar N, Hahm JI. Novel telomeric repeat elongation assay performed on zinc oxide nanorod array supports. J Nanosci Nanotechnol 2008;8:410-15
   PubMed Web of Science ®Google Scholar
• Lee H, Lee E, Kim do K, Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging. J Am Chem Soc 2006;128:7383-9
   PubMed Web of Science ®Google Scholar
• Jain TK, Richey J, Strand M, Magnetic nanoparticles with dual functional properties: drug delivery and magnetic resonance imaging. Biomaterials 2008;29:4012-21
   PubMed Web of Science ®Google Scholar
• Li Z, Xiang J, Zhang W, Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model. Cancer Gene Ther 2009;16:423-9
   PubMed Web of Science ®Google Scholar
• Nie L, Gao L, Yan X, Wang T. Functionalized tetrapod-like ZnO nanostructures for plasmid DNA purification, polymerase chain reaction and delivery. Nanotechnology 2007;18:015101-7
   Web of Science ®Google Scholar
• Zhang P, Liu W. ZnO QD@PMAA-co-PDMAEMA nonviral vector for plasmid DNA delivery and bioimaging. Biomaterials 2010;31:3087-94
   PubMed Web of Science ®Google Scholar
• Gojova A, Guo B, Kota RS, Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ Health Perspect 2007;115:403-9
   PubMed Web of Science ®Google Scholar
• Beyerle A, Schulz H, Kissel T, Stoeger T. Screening strategy to avoid toxicological hazards of inhaled nanoparticles for drug delivery: the use of alpha-quartz and nano zinc oxide particles as benchmark. Inhaled Particles 2009;151:1-9
   Google Scholar
• Croft M. The role of TNF superfamily members in T-cell function and diseases. Nat Rev Immunol 2009;9:271-85
   PubMed Web of Science ®Google Scholar
• Lappin MB, Campbell JD. The Th1-Th2 classification of cellular immune responses: concepts, current thinking and applications in haematological malignancy. Blood Rev 2000;14:228-39
   PubMed Web of Science ®Google Scholar
• Zhang L, Gu FX, Chan JM, Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 2008;83:761-9
   PubMed Web of Science ®Google Scholar
• Kehrer DF, Bos AM, Verweij J, Phase I and pharmacologic study of liposomal lurtotecan, NX 211: urinary excretion predicts hematologic toxicity. J Clin Oncol 2002;20:1222-31
   PubMed Web of Science ®Google Scholar
• Cicek M, Iwaniec UT, Goblirsch MJ, 2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo. Cancer Res 2007;67:10106-11
   PubMed Web of Science ®Google Scholar
• Dragovich T, Mendelson D, Kurtin S, A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer. Cancer Chemother Pharmacol 2006;58:759-64
   PubMed Web of Science ®Google Scholar
• Goel R, Shah N, Visaria R, Biodistribution of TNF-alpha-coated gold nanoparticles in an in vivo model system. Nanomedicine 2009;4:401-10
   PubMed Web of Science ®Google Scholar
• Gratton SE, Williams SS, Napier ME, The pursuit of a scalable nanofabrication platform for use in material and life science applications. Acc Chem Res 2008;41:1685-95
   PubMed Web of Science ®Google Scholar
• Gobin AM, Watkins EM, Quevedo E, Near-infrared-resonant gold/gold sulfide nanoparticles as a photothermal cancer therapeutic agent. Small 2010;6:745-52
   PubMed Web of Science ®Google Scholar
• Fonseca MJ, Jagtenberg JC, Haisma HJ, Storm G. Liposome-mediated targeting of enzymes to cancer cells for site-specific activation of prodrugs: comparison with the corresponding antibody-enzyme conjugate. Pharm Res 2003;20:423-8
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Batrakova EV, Alakhov VY. Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. J Control Release 2002;82:189-12
   PubMed Web of Science ®Google Scholar
• Wong HL, Rauth AM, Bendayan R, Wu XY. In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. Eur J Pharm Biopharm 2007;65:300-8
   PubMed Web of Science ®Google Scholar
• Farokhzad OC, Cheng J, Teply BA, Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci USA 2006;103:6315-20
   PubMed Web of Science ®Google Scholar
• Raffaghello L, Zuccari G, Carosio R, In vitro and in vivo antitumor activity of the novel derivatized polyvinyl alcohol-based polymer P10(4). Clin Cancer Res 2006;12:3485-93
   PubMed Web of Science ®Google Scholar
• Kukowska-Latallo JF, Candido KA, Cao Z, Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res 2005;65:5317-24
   PubMed Web of Science ®Google Scholar
• Morgan MT, Nakanishi Y, Kroll DJ, Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res 2006;66:11913-21
   PubMed Web of Science ®Google Scholar
• Wosikowski K, Biedermann E, Rattel B, In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells. Clin Cancer Res 2003;9:1917-26
   PubMed Web of Science ®Google Scholar
• Chavanpatil MD, Khdair A, Panyam J. Surfactant-polymer nanoparticles: a novel platform for sustained and enhanced cellular delivery of water-soluble molecules. Pharm Res 2007;24:803-10
   PubMed Web of Science ®Google Scholar
• Hyung PJ, Kwon S, Lee M, Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activity. Biomaterials 2006;27:119-26
   PubMed Web of Science ®Google Scholar
• Everts M, Saini V, Leddon JL, Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Lett 2006;6:587-91
   PubMed Web of Science ®Google Scholar
• Hirsch LR, Stafford RJ, Bankson JA, Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci USA 2003;100:13549-54
   PubMed Web of Science ®Google Scholar
• Roy I, Ohulchanskyy TY, Pudavar HE, Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy. J Am Chem Soc 2003;125:7860-5
   PubMed Web of Science ®Google Scholar