391
Views
33
CrossRef citations to date
0
Altmetric
Reviews

Methods for quantifying intrafollicular drug delivery: a critical appraisal

, BSc MSc MPharmS PhD
Pages 1095-1108 | Published online: 16 Jul 2010

Bibliography

  • Frum Y, Bonner MC, Eccleston GM, The influence of drug partition coefficient on follicular penetration: in vitro human skin studies. Eur J Pharm Sci 2007;30:280-7
  • Lademann J, Richter H, Meinke M, Which skin model is the most appropriate for the investigation of topically applied substances into the hair follicles? Skin Pharmacol Physiol 2010;23:47-52
  • Grice JE, Ciotti S, Weiner N, Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. J Pharm Sci 2010;99:712-18
  • Meidan VM, Roper CS. Inter and intra-individual variability in human skin barrier function: a large scale retrospective study. Toxicol In Vitro 2008;22:1062-9
  • Touitou E, Meidan VM, Horwitz E. Methods for quantitative determination of drug localized in the skin. J Control Release 1998;56:7-21
  • Whiting DA. Histology of normal hair. In: Hordinsky MK, Sawaya ME, Scher RK, editors, Atlas of hair and nails. Churchill Livingstone, Philadelphia; 2000. p. 918
  • Poblet E, Ortega F, Jimenez F. The arector pili muscle and the follicular unit of the scalp: a microscopic anatomy study. Dermatol Surg 2002;28:800-3
  • Bullough WS. Chalone control mechanisms. Life Sci 1975;16:323-30
  • Foitzik K, Langan EA, Paus R. Prolactin and the skin. A dermatological perspective on an ancient plietropic peptide hormone. J Invest Dermatol 2009;129:1079-87
  • Clarys P, Barel A. Quantitative evaluation of skin surface lipids. Clin Dermatol 1995;13:307-21
  • Kao J, Hall J, Helman G. In vitro percutaneous absorption in mouse skin: influence of skin appendages. Toxicol Appl Pharmacol 1988;94:93-103
  • Del Terzo S, Behl CR, Nash RA. Iontophoretic transport of a homologous series of ionized and nonionized model compounds: influence of hydrophobicity and mechanistic interpretation. Pharm Res 1989;6:85-90
  • Hisoire G, Bucks D. An unexpected finding in percutaneous absorption observed between haired and hairless guinea pig skin. J Pharm Sci 1997;86:398-400
  • Honzak L, Sentjurc M, Swartz HM. In vivo EPR of topical delivery of a hydrophilic substance encapsulated in multilamellar liposomes applied to the skin of hairless and normal mice. J Control Release 2000;66:221-8
  • Shim J, Seok Kang H, Park WS, Transdermal delivery of minoxidil with block copolymer nanoparticles. J Control Release 2004;97:477-84
  • Lauer AC, Elder JT, Weiner ND. Evaluation of the hairless rat as a model for in vivo percutaneous absorption. J Pharm Sci 1997;86:13-8
  • Ogiso T, Niinaka N, Iwaki M. Mechanism for enhancement effect of lipid disperse system on percutaneous absorption. J Pharm Sci 1996;15:57-64
  • Behl CR, Wittkowsky A, Barrett M, Technique for preparing appendage-free skin (scar) on hairless mouse. J Pharm Sci 1981;70:835-7
  • Illel B, Schaefer H. Transfollicular percutaneous absorption. Skin model for quantitative studies. Acta Derm Venereol 1988;68:427-30
  • Illel B, Schaefer H, Wepierre J, Follicles play an important role in percutaneous absorption. J Pharm Sci 1991;80:424-7
  • Bamba FL, Wepierre J. Role of the appendageal pathway in the percutaneous absorption of pyridostigmine bromide in various vehicles. Eur J Drug Metab Pharmacokinet 1993;18:339-48
  • Hueber F, Wepierre J, Schaefer H. Role of transepidermal and transfollicular routes in percutaneous absorption of hydrocortisone and testosterone: in vivo study in the hairless rat. Skin Pharmacol 1992;5:99-107
  • Bernard E, Dubois JL, Wepierre J. Importance of sebaceous glands in cutaneous penetration of an antiandrogen: target effect of liposomes. J Pharm Sci 1997;86:573-8
  • Hueber F, Schaefer H, Wepierre J. Role of transepidermal and transfollicular routes in percutaneous absorption of steroids: in vitro studies on human skin. Skin Pharmacol 1994;7:237-44
  • Schaefer H, Watts F, Brod J, Follicular penetration. In: Scott RC, Guy RH, Hadgraft J, editors, Prediction of percutaneous penetration: methods, measurements and modelling. IBC Technical Services, London; 1990
  • Meidan VM, Docker M, Walmsley AD, Low intensity ultrasound as a probe to elucidate the relative follicular contribution to total transdermal absorption. Pharm Res 1998;15:85-92
  • Valiveti S, Lu GW. Diffusion properties of model compounds in artificial sebum. Int J Pharm 2007;345:88-94
  • Valiveti S, Wesley J, Lu GW. Investigation of drug partition property in artificial sebum. Int J Pharm 2008;346:10-6
  • Teichmann A, Otberg N, Jacobi U, Follicular penetration: development of a method to block the follicles selectively against the penetration of topically applied substances. Skin Pharmacol Physiol 2006;19:216-23
  • Trauer S, Patzelt A, Otberg N, Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data. Br J Clin Pharmacol 2009;68:181-6
  • Abdulmajed K, Heard CM. Topical delivery of retinyl ascorbate 3. Influence of follicle sealing and skin stretching. Skin Pharmacol Physiol 2008;21:46-9
  • Otberg N, Teichmann A, Rasujev U, Follicular penetration of topically applied caffeine via a shampoo formulation. Skin Pharmacol Physiol 2007;20:195-8
  • Otberg N, Patzelt A, Rasulev U, The role of hair follicles in the percutaneous absorption of caffeine. Br J Clin Pharmacol 2008;65:488-92
  • El Maghraby GM, Williams AC, Barry BW. Skin hydration and possible shunt route penetration in controlled estradiol delivery from ultradeformable and standard liposomes. J Pharm Pharmacol 2001;53:1311-22
  • Barry BW. Drug delivery routes in skin: a novel approach. Adv Drug Deliv Rev 2002;54:S31-40
  • Essa EA, Bonner MC, Barry BW. Human skin sandwich for assessing shunt route penetration during passive and iontophoretic drug and liposome delivery. J Pharm Pharmacol 2002a;54:1481-90
  • Frum Y, Eccleston GM, Meidan VM. In vitro permeation of drugs into porcine hair follicles: Is it quantitatively equivalent to permeation into human hair follicles? J Pharm Pharmacol 2008;60:145-51
  • Mowafy M, Cassens RG. Microscopic structure of pig skin. J Anim Sci 1975;41:1281-90
  • Winter GD. Healing. In: Maibach HL, Rovee DT, editors, Epidermal regeneration studied in the domestic pig. Epidermal wound healing. Year Book Medical Publishers, Chicago; 1972
  • Bronaugh RL, Stewart RF, Congdon ER. Methods for in vitro percutaneous absorption studies. II. Animal models for human skin. Toxicol Appl Pharmacol 1982;62:481-8
  • Otberg N, Richter H, Schaefer H, Variations of hair follicle size and distribution in different body sites. J Invest Dermatol 2004;122:14-9
  • Meyer W, Kacza J, Zschemisch NH, Observations on the actual structural conditions in the stratum superficiale dermidis of porcine ear skin, with special reference to its use as model for human skin. Ann Anat 2007;189:143-56
  • Schaefer H, Redelmeier TE. Skin barrier principles of percutaneous absorption. In: Schaefer H, Redelmeier TE, editors, Skin barrier principles of percutaneous absorption. Karger, Basel; 1996
  • Vardaxis NJ, Brans TA, Boon ME, Confocal laser scanning microscopy of porcine skin: implications for human wound healing studies. J Anat 1997;190:601-11
  • Frum Y, Eccleston GM, Meidan VM. Factors affecting hydrocortisone permeation into human hair follicles: use of the skin sandwich system. Int J Pharm 2008;358:144-50
  • Teichmann A, Jacobi U, Ossadnik M, Differential stripping: determination of the amount of topically applied substances penetrated into the hair follicles. J Invest Dermatol 2005;125:264-9
  • Lademann J, Richter H, Teichmann A, Nanoparticles – an efficient carrier for drug delivery into the hair follicles. Eur J Pharm Biopharm 2007;66:159-64
  • Ossadnik M, Czaika V, Teichmann A, Differential stripping: introduction of a method to show the penetration of topically applied antifungal substances into the hair follicles. Mycoses 2007;50:457-62
  • Patzelt A, Richter H, Buettemeyer R, Differential stripping demonstrates a significant reduction of the hair follicle reservoir in vitro compared to in vivo. Eur J Pharm Biopharm 2008;70:234-8
  • Starcher B, Aycock RL, Hill CH. Multiple roles for elastic fibers in the skin. J Histochem Cytochem 2005;53:431-44
  • Stromberg MW, Hwang YC, Monteiro-Riviere NA. Interfollicular smooth muscle in the skin of the domesticated pig (Sus scrofa). Anat Rec 1981;201:455-62
  • Fabin B, Touitou E. Localization of lipophilic molecules penetrating rat skin in vivo by quantitative autoradiography. Int J Pharm 1991;74:59-65
  • Touitou E, Levi-Schaffer F, Dayan N, Modulation of caffeine skin delivery by carrier design: liposomes versus permeation enhancers. Int J Pharm 1994;103:131-6
  • Gautier B, Bernard BA. On the use of Micro-Imager to directly visualize drug distribution in human skin. Skin Pharmacol Appl Skin Physiol 2001;14:41-5
  • Grams YY, Whitehead L, Cornwell P, On-line visualization of dye diffusion in fresh unfixed human skin. Pharm Res 2004;21:851-9
  • Grams YY, Whitehead L, Cornwell P, Time and depth resolved visualisation of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin. J Control Release 2004;98:367-78
  • Grams YY, Whitehead L, Lamers G, On-line diffusion profile of a lipophilic model dye in different depths of a hair follicle in human scalp skin. J Invest Dermatol 2005;125:775-82
  • Rancan F, Papakostas D, Hadam S, Investigation of polylactic acid (PLA) nanoparticles as drug delivery systems for local dermatotherapy. Pharm Res 2009;26:2027-36
  • Wu X, Price GJ, Guy RH. Disposition of nanoparticles and an associated lipophilic permeant following topical application to the skin. Mol Pharmaceut 2009;6:1441-8
  • Caspers PJ, Lucassen GW, Puppels GJ. Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin. Biophys J 2003;85:572-80
  • Otberg N, Richter H, Knuttel A, Laser spectroscopic methods for the characterization of open and closed follicles. Laser Phys Lett 2004;1:46-9
  • Pappas A. Epidermal surface lipids. Dermatoendocrinology 2009;1:72-6
  • Picardo M, Ottaviani M, Camera E. Sebaceous glands lipids. Dermatoendocrinology 2009;1:68-71
  • Meidan VM, Bonner MC, Michniak BB. Transfollicular drug delivery – is it a reality? Int J Pharm 2005;306:1-14
  • Wosicka H, Cla K. Targeting the hair follicles: current status and potential. J Dermatol Sci 2010;57:83-9
  • Chourasia R, Jain SK. Drug targeting through pilosebaceous route. Curr Drug Targets 2009;10:950-67
  • Motwani MR, Rhein LD, Zatz JL. Differential scanning calorimetry studies of sebum models. J Cosmet Sci 2001;52:211-24
  • Motwani MR, Rhein LD, Zatz JL. Influence of vehicles on the phase transitions of model sebum. J Cosmet Sci 2002;53:35-42
  • Musial W, Kubis A. Preliminary assessment of alginic acid as a factor buffering triethanolamine interacting with artificial skin sebum. Eur J Pharm Biopharm 2003;55:237-40
  • Stefaniak AB, Harvey CJ. Dissolution of materials in artificial skin surface liquids. Toxicol In Vitro 2006;20:1265-83
  • Wertz PW. Human synthetic sebum formulation and stability under conditions of use and storage. Int J Cosmet Sci 2009;31:21-5
  • Lu GW, Valiveti S, Spence J, Comparison of artificial sebum with human and hamster sebum samples. Int J Pharm 2009;367:37-43
  • Lian G, Chen L, Han L. An evaluation of mathematical models for predicting skin permeability. J Pharm Sci 2008;97:584-98
  • Wallace SM, Barnett G. Pharmacokinetic analysis of percutaneous absorption: evidence of parallel penetration pathways for methotrexate. J Pharmacokinet Biopharm 1978;6:315-25
  • Keister JC, Kasting GB. The use of transient diffusion to investigate transport pathways through skin. J Control Release 1986;4:111-7
  • Mitragotri S. Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways. J Control Release 2003;86:69-92
  • Ho CK. Probabilistic modeling of percutaneous absorption for risk-based exposure assessments and transdermal drug delivery. Stat Method 2004;1:47-69
  • Yuan Y, Verma R. Measuring microelastic properties of stratum corneum. Colloids Surf B Bionterfaces 2006;48:6-12
  • Cevc G, Vierl U. Nanotechnology and the transdermal route. A state of the art and critical appraisal. J Control Release 2010;141:277-99
  • Ohyama M. Hair follicle bulge: a fascinating reservoir of epithelial stem cells. J Dermatol Sci 2007;46:81-9
  • Trueb RM. Hormones and hair growth. Hautarzt 2010;61:487-96
  • Meidan V, Touitou E. Treatments for androgenetic alopecia and alopecia areata: current options and future prospects. Drugs 2001;61:53-69
  • Youn SW. The role of facial sebum secretion in acne pathogenesis: facts and controversies. Clin Dermatol 2010;28:8-11

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.