Bibliography
- Reichert J. Development trends for peptide therapeutics – A comprehensive quantitative analysis of peptide therapeutics in clinical development. Available from: www peptidetherapeutics org [Last accessed 30 September 2010]
- Zompra AA, Galanis AS, Werbitzky O, Albericio F. Manufacturing peptides as active pharmaceutical ingredients. Fut Med Chem 2009;1:361-77
- Vlieghe P, Lisowski V, Martinez J, Khrestchatisky M. Synthetic therapeutic peptides: science and market. Drug Discov Today 2010;15:40-56
- Pichereau C, Allary C. Therapeutic peptides under the spotlight. Eur BioPharm Rev 2005:88-93
- Ayoub M, Scheidegger D. Peptide drugs, overcoming the challenges, a growing business. Chim Oggi 2006;24:46-8
- Haberkorn U, Eisenhut M. Molecular imaging and therapy – a programme based on the development of new biomolecules. Eur J Nucl Med Mol Imaging 2005;32:1354-9
- Yuan L, Kurek I, English J, Keenan R. Laboratory-directed protein evolution. Microbiol Mol Biol Rev 2005;69:373-92
- Ovadia O, Greenberg S, Laufer B, Improvement of drug-like properties of peptides: the somatostatin paradigm. Expert Opin Drug Discov 2010;5:655-71
- Werle M, Bernkop-Schnurch A. Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids 2006;30:351-67
- Chaturvedula A, Joshi DP, Anderson C, In vivo iontophoretic delivery and pharmacokinetics of salmon calcitonin. Int J Pharm 2005;297:190-6
- Zhang Q, Grice JE, Wang GJ, Roberts MS. Cutaneous metabolism in transdermal drug delivery. Curr Drug Metab 2009;10:227-35
- Schuetz YB, Naik A, Guy RH, Transdermal iontophoretic delivery of triptorelin in vitro. J Pharm Sci 2005;94:2175-82
- Green PG. Iontophoretic delivery of peptide drugs. J Control Release 1996;41:33-48
- Kalia YN, Naik A, Garrison J, Guy RH. Iontophoretic drug delivery. Adv Drug Deliv Rev 2004;56:619-58
- Burnette RR, Marrero D. Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised nude mouse skin. J Pharm Sci 1986;75:738-43
- Marchand JE, Hagino N. Effect of iontophoresis of vasopressin on lateral septal neurons. Exp Neurol 1982;78:790-5
- Siddiqui O, Sun Y, Liu JC, Chien YW. Facilitated transdermal transport of insulin. J Pharm Sci 1987;76:341-5
- Stephen RL, Petelenz TJ, Jacobsen SC. Potential novel methods for insulin administration: I. Iontophoresis. Biomed Biochim Acta 1984;43:553-8
- Subramony JA, Sharma A, Phipps JB. Microprocessor controlled transdermal drug delivery. Int J Pharm 2006;317:1-6
- Phipps JB, Padmanabhan RV, Lattin GA. Iontophoretic delivery of model inorganic and drug ions. J Pharm Sci 1989;78:365-9
- Abla N, Naik A, Guy RH, Kalia YN. Contributions of electromigration and electroosmosis to peptide iontophoresis across intact and impaired skin. J Control Release 2005;108:319-30
- Delgado-Charro MB, Guy RH. Transdermal iontophoresis for controlled drug delivery and non-invasive monitoring. STP Pharm Sci 2001;11:403-14
- Phipps JB, Gyory JR. Transdermal ion migration. Adv Drug Deliv Rev 1992;9:137-76
- Sage BH, Riviere JE. Model systems in iontophoresis transport efficacy. Adv Drug Deliv Rev 1992;9:265-87
- Mudry B, Guy RH, Begona Delgado-Charro M. Prediction of iontophoretic transport across the skin. J Control Release 2006;111:362-7
- Mudry B, Guy RH, Delgado-Charro MB. Transport numbers in transdermal iontophoresis. Biophys J 2006;90:2822-30
- Mudry B, Guy RH, Delgado-Charro MB. Electromigration of ions across the skin: determination and prediction of transport numbers. J Pharm Sci 2006;95:561-9
- Kasting GB, Keister JC. Application of electrodiffusion theory for a homogeneous membrane to iontophoretic transport through skin. J Control Release 1989;8:195-210
- Marro D, Guy RH, Delgado-Charro MB. Characterization of the iontophoretic permselectivity properties of human and pig skin. J Control Release 2001;70:213-17
- Pikal MJ, Shah S. Transport mechanisms in iontophoresis. 3. An experimental-study of the contributions of electroosmotic flow and permeability change in transport of low and high-molecular-weight solutes. Pharm Res 1990;7:222-9
- Pikal MJ. Transport mechanisms in iontophoresis. 1. A theoretical model for the effect of electroosmotic flow on flux enhancement in transdermal iontophoresis. Pharm Res 1990;7:118-26
- Pikal MJ, Shah S. Transport mechanisms in iontophoresis. 2. Electroosmotic flow and transference number measurements for hairless mouse skin. Pharm Res 1990;7:213-21
- Pikal MJ. The role of electroosmotic flow in transdermal iontophoresis. Adv Drug Deliv Rev 2001;46:281-305
- Green PG, Hinz RS, Kim A, Iontophoretic delivery of a series of tripeptides across the skin in vitro. Pharm Res 1991;8:1121-7
- Cazares-Delgadillo J, Naik A, Ganem-Rondero A, Transdermal delivery of cytochrome C-A 12.4 kDa protein-Across intact skin by constant-current iontophoresis. Pharm Res 2007;24:1360-8
- Schuetz YB, Naik A, Guy RH, Transdermal iontophoretic delivery of vapreotide acetate across porcine skin in vitro. Pharm Res 2005;22:1305-12
- Schuetz YB, Naik A, Guy RH, Kalia YN. Effect of amino acid sequence on transdermal iontophoretic peptide delivery. Eur J Pharm Sci 2005;26:429-37
- Hirvonen J, Kalia YN, Guy RH. Transdermal delivery of peptides by iontophoresis. Nat Biotechnol 1996;14:1710-13
- Guy RH, Kalia YN, Delgado-Charro MB, Iontophoresis: electrorepulsion and electroosmosis. J Control Release 2000;64:129-32
- Dubey S, Kalia YN. Non-invasive iontophoretic delivery of enzymatically active ribonuclease A (13.6 kDa) across intact porcine and human skins. J Control Release 2010;145:203-9
- Chang SL, Hofmann GA, Zhang L, Stability of a transdermal salmon calcitonin formulation. Drug Deliv 2003;10:41-5
- Patel SR, Zhong H, Sharma A, Kalia YN. In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate. Eur J Pharm Biopharm 2007;66:296-301
- Patel SR, Zhong H, Sharma A, Kalia YN. Controlled non-invasive transdermal iontophoretic delivery of zolmitriptan hydrochloride in vitro and in vivo. Eur J Pharm Biopharm 2009;72:304-9
- Lau DT, Sharkey JW, Petryk L, Effect of current magnitude and drug concentration on iontophoretic delivery of octreotide acetate (Sandostatin) in the rabbit. Pharm Res 1994;11:1742-6
- Green P, Shroot B, Bernerd F, In vitro and in vivo iontophoresis of a tripeptide across nude rat skin. J Control Release 1992;20:209-18
- Craane-Vanhinsberg WHM, Bax L, Flinterman NHM, Iontophoresis of a model peptide across human skin in-vitro – Effects of iontophoresis protocol, pH, and ionic strength on peptide flux and skin impedance. Pharm Res 1994;11:1296-300
- Ledger PW. Skin biological issues in electrically enhanced transdermal delivery. Adv Drug Deliv Rev 1992;9:289-307
- Huang YY, Wu SM, Wang CY. Response surface method: a novel strategy to optimize iontophoretic transdermal delivery of thyrotropin-releasing hormone. Pharm Res 1996;13:547-52
- Knoblauch P, Moll F. In-vitro pulsatile and continuous transdermal delivery of buserelin by iontophoresis. J Control Release 1993;26:203-12
- Kumar S, Hing C, Patel S, Effect of Iontophoresis on in vitro skin permeation of an analog of growth-hormone releasing-factor in the hairless guinea-pig model. J Pharm Sci 1992;81:635-9
- Abu Hashim II, Motoyama K, Abd-ElGawad AEH, Potential use of iontophoresis for transdermal delivery of NF-kappa B decoy oligonucleotides. Int J Pharm 2010;393:127-34
- Kanebako M, Inagi T, Takayama K. Evaluation of skin barrier function using direct current II: effects of duty cycle, waveform, frequency and mode. Biol Pharm Bull 2002;25:1623-8
- Prausnitz MR. The effects of electric current applied to skin: a review for transdermal drug delivery. Adv Drug Deliv Rev 1996;18:395-425
- Raiman J, Koljonen M, Huikko K, Delivery and stability of LHRH and Nafarelin in human skin: the effect of constant/pulsed iontophoresis. Eur J Pharm Sci 2004;21:371-7
- Rodriguez Bayon AM, Guy RH. Iontophoresis of nafarelin across human skin in vitro. Pharm Res 1996;13:798-800
- Delgado-Charro MB, Guy RH. Characterization of convective solvent flow during iontophoresis. Pharm Res 1994;11:929-35
- Delgado-Charro MB, Rodriguez-Bayon AM, Guy RH. Iontophoresis of Nafarelin – Effects of current density and concentration on electrotransport in vitro. J Control Release 1995;35:35-40
- Delgado-Charro MB, Guy RH. Iontophoretic delivery of Nafarelin across the skin. Int J Pharm 1995;117:165-72
- Hirvonen J, Guy RH. Iontophoretic delivery across the skin: electroosmosis and its modulation by drug substances. Pharm Res 1997;14:1258-63
- Hoogstraate AJ, Srinivasan V, Sims SM, Higuchi WI. Iontophoretic enhancement of peptides – Behavior of Leuprolide versus model permeants. J Control Release 1994;31:41-7
- Lu MF, Lee D, Carlson R, The effects of formulation variables on iontophoretic transdermal delivery of Leuprolide to humans. Drug Dev Ind Pharm 1993;19:1557-71
- Nair V, Panchagnula R. Physicochemical considerations in the iontophoretic delivery of a small peptide: in vitro studies using arginine vasopressin as a model peptide. Pharmacol Res 2003;48:175-82
- Marro D, Kalia YN, Delgado-Charro MB, Guy RH. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Pharm Res 2001;18:1701-8
- Green PG, Hinz RS, Cullander C, Iontophoretic delivery of amino acids and amino acid derivatives across the skin in vitro. Pharm Res 1991;8:1113-20
- Panchagnula R, Bindra P, Kumar N, Stability of insulin under iontophoretic conditions. Pharmazie 2006;61:1014-18
- Tokumoto S, Higo N, Sugibayashi K. Effect of electroporation and pH on the iontophoretic transdermal delivery of human insulin. Int J Pharm 2006;326:13-19
- Levin J, Maibach H. Human skin buffering capacity: an overview. Skin Res Technol 2008;14:121-6
- Shukla C, Friden P, Juluru R, Stagni G. In vivo quantification of acyclovir exposure in the dermis following iontophoresis of semisolid formulations. J Pharm Sci 2009;98:917-25
- Delgado-Charro MB. Recent advances on transdermal iontophoretic drug delivery and non-invasive sampling. J Drug Deliv Sci Technol 2009;19:75-88
- Marro D, Kalia YN, Delgado-Charro MB, Guy RH. Optimizing iontophoretic drug delivery: identification and distribution of the charge-carrying species. Pharm Res 2001;18:1709-13
- Alvarez-Figueroa MJ, Blanco-Mendez J. Transdermal delivery of methotrexate: iontophoretic delivery from hydrogels and passive delivery from microemulsions. Int J Pharm 2001;215:57-65
- Haak RP, Gyory JR, Theeuwes F, Iontophoretic delivery device and methods of hydrating same. US5320598; 1994
- Fang JY, Hsu LR, Huang YB, Tsai YH. Evaluation of transdermal iontophoresis of enoxacin from polymer formulations: in vitro skin permeation and in vivo microdialysis using Wistar rat as an animal model. Int J Pharm 1999;180:137-49
- Fang JY, Sung KC, Hu OYP, Chen HY. Transdermal delivery of nalbuphine and nalbuphine pivalate from hydrogels by passive diffusion and iontophoresis. Arzneimittelforschung 2001;51:408-13
- Fang JY, Sung KC, Wang JJ, The effects of iontophoresis and electroporation on transdermal delivery of buprenorphine from solutions and hydrogels. J Pharm Pharmacol 2002;54:1329-37
- Jyoung JY, Shim BS, Cho DE, Hwang IS. Iontophoretic transdermal delivery of alendronate in hairless mouse skin. Polym Korea 2009;33:237-42
- Taveira SF, Nomizo A, Lopez RFV. Effect of the iontophoresis of a chitosan gel on doxorubicin skin penetration and cytotoxicity. J Control Release 2009;134:35-40
- Merclin N, Bramer T, Edsman K. Iontophoretic delivery of 5-aminolevulinic acid and its methyl ester using a carbopol gel as vehicle. J Control Release 2004;98:57-65
- Banga AK, Chien YW. Hydrogel-based iontotherapeutic delivery devices for transdermal delivery of peptide/protein drugs. Pharm Res 1993;10:697-702
- Tatavarti AS, Mehta KA, Augsburger LL, Hoag SW. Influence of methacrylic and acrylic acid polymers on the release performance of weakly basic drugs from sustained release hydrophilic matrices. J Pharm Sci 2004;93:2319-31
- Essa EA, Bonner MC, Barry BW. Iontophoretic estradiol skin delivery and tritium exchange in ultradeformable liposomes. Int J Pharm 2002;240:55-66
- Fang JY, Sung KC, Lin HH, Fang CL. Transdermal iontophoretic delivery of enoxacin from various liposome-encapsulated formulations. J Control Release 1999;60:1-10
- Han I, Kim M, Kim J. Enhanced transfollicular delivery of adriamycin with a liposome and iontophoresis. Exp Dermatol 2004;13:86-92
- Vutla NB, Betageri GV, Banga AK. Transdermal iontophoretic delivery of enkephalin formulated in liposomes. J Pharm Sci 1996;85:5-8
- Manosroi A, Khositsuntiwong N, Gotz F, Transdermal enhancement through rat skin of luciferase plasmid DNA loaded in elastic nanovesicles. J Liposome Res 2009;19:91-8
- Kantaria S, Rees GD, Lawrence MJ. Gelatin-stabilised microemulsion-based organogels: rheology and application in iontophoretic transdermal drug delivery. J Control Release 1999;60:355-65
- Sintov AC, Brandys-Sitton R. Facilitated skin penetration of lidocaine: combination of a short-term iontophoresis and microemulsion formulation. Int J Pharm 2006;316:58-67
- Liu W, Hu M, Liu W, Investigation of the carbopol gel of solid lipid nanoparticles for the transdermal iontophoretic delivery of triamcinolone acetonide acetate. Int J Pharm 2008;364:135-41
- Joo HH, Lee HY, Kim JC, Integrities and skin permeation-enhancing characteristics of behenic acid nanoparticles. J Dispers Sci Technol 2009;30:149-54
- Li J, Zhai YL, Zhang B, Methoxy poly(ethylene glycol)-block-poly(D,L-lactic acid) copolymer nanoparticles as carriers for transdermal drug delivery. Polym Int 2008;57:268-74
- Miyazaki S, Takahashi A, Kubo W, Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration. J Pharm Pharm Sci 2003;6:238-45
- Luengo J, Weiss B, Schneider M, Influence of nanoencapsulation on human skin transport of flufenamic acid. Skin Pharmacol Physiol 2006;19:190-7
- Stracke F, Weiss B, Lehr CM, Multiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs. J Invest Dermatol 2006;126:2224-33
- Boinpally RR, Zhou SL, Devraj G, Iontophoresis of lecithin vesicles of cyclosporin A. Int J Pharm 2004;274:185-90
- Abla N, Naik A, Guy RH, Kalia YN. Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis. Pharm Res 2005;22:2069-78
- Schuetz YB, Carrupt PA, Naik A, Structure-permeation relationships for the non-invasive transdermal delivery of cationic peptides by iontophoresis. Eur J Pharm Sci 2006;29:53-9
- Abla N, Geiser L, Mirgaldi M, Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility. J Pharm Sci 2005;94:2667-75
- Henchoz Y, Abla N, Veuthey JL, Carrupt PA. A fast screening strategy for characterizing peptide delivery by transdermal iontophoresis. J Control Release 2009;137:123-9
- Banga AK, Chien YW. Characterization of in-vitro transdermal iontophoretic delivery of insulin. Drug Dev Ind Pharm 1993;19:2069-87
- Langkjaer L, Brange J, Grodsky GM, Guy RH. Iontophoresis of monomeric insulin analogues in vitro: effects of insulin charge and skin pretreatment. J Control Release 1998;51:47-56
- Pillai O, Panchagnula R. Transdermal iontophoresis of insulin – V. Effect of terpenes. J Control Release 2003;88:287-96
- Pillai O, Borkute SD, Sivaprasad N, Panchagnula R. Transdermal iontophoresis of insulin – II. Physicochemical considerations. Int J Pharm 2003;254:271-80
- Pillai O, Nair V, Panchagnula R. Transdermal iontophoresis of insulin: IV. Influence of chemical enhancers. Int J Pharm 2004;269:109-20
- Li Y, Quan Y, Zang L, Trypsin as a novel potential absorption enhancer for improving the transdermal delivery of macromolecules. J Pharm Pharmacol 2009;61:1005-12
- Rastogi R, Anand S, Dinda AK, Koul V. Investigation on the synergistic effect of a combination of chemical enhancers and modulated iontophoresis for transdermal delivery of insulin. Drug Dev Ind Pharm 2010;36:993-1004
- Rastogi SK, Singh J. Effect of chemical penetration enhancer and iontophoresis on the in vitro percutaneous absorption enhancement of insulin through porcine epidermis. Pharm Dev Technol 2005;10:97-104
- Kanikkannan N, Singh J, Ramarao P. Transdermal iontophoretic delivery of bovine insulin and monomeric human insulin analogue. J Control Release 1999;59:99-105
- Kari B. Control of blood-glucose levels in alloxan-diabetic rabbits by iontophoresis of insulin. Diabetes 1986;35:217-21
- Tomohira Y, Machida Y, Onishi H, Nagai T. Iontophoretic transdermal absorption of insulin and calcitonin in rats with newly-devised switching technique and addition of urea. Int J Pharm 1997;155:231-9
- Abla N, Naik A, Guy RH, Kalia YN. Iontohoresis: clinical applications and future challenges. In: Smith EW, Maibach HI, editors, Percutaneous penetration enhancers. 2nd edition; Taylor & Francis, Bristol PA, USA. 2005
- Murthy SN, Zhao YL, Hui SW, Sen A. Synergistic effect of anionic lipid enhancer and electroosmosis for transcutaneous delivery of insulin. Int J Pharm 2006;326:1-6
- Kogure K, Yamamoto M, Watanabe M, Transdermal delivery of insulin-encapsulated liposomes via iontophoresis. Yakugaku Zasshi 2008;128:81-2
- Chen HB, Zhu HD, Zheng JN, Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin. J Control Release 2009;139:63-72
- Torres-Lugo M, Peppas NA. Transmucosal delivery systems for calcitonin: a review. Biomaterials 2000;21:1191-6
- Lee WA, Ennis RD, Longenecker JP, Bengtsson P. The bioavailability of intranasal salmon calcitonin in healthy volunteers with and without a permeation enhancer. Pharm Res 1994;11:747-50
- Chang SL, Hofmann GA, Zhang L, Transdermal iontophoretic delivery of salmon calcitonin. Int J Pharm 2000;200:107-13
- Morimoto K, Iwakura Y, Nakatani E, Effect of proteolytic-enzyme inhibitors as absorption enhancers on the transdermal iontophoretic delivery of calcitonin in rats. J Pharm Pharmacol 1992;44:216-18
- Nakamura K, Katagai K, Mori K, Transdermal administration of salmon calcitonin by pulse depolarization-iontophoresis in rats. Int J Pharm 2001;218:93-102
- Santi P, Colombo P, Bettini R, Drug reservoir composition and transport of salmon calcitonin in transdermal iontophoresis. Pharm Res 1997;14:63-6
- Thysman S, Hanchard C, Preat V. Human calcitonin delivery in rats by iontophoresis. J Pharm Pharmacol 1994;46:725-30
- Santi P, Volpato NM, Bettini R, Transdermal iontophoresis of salmon calcitonin can reproduce the hypocalcemic effect of intravenous administration. Farmaco 1997;52:445-8
- Suzuki Y, Iga K, Yanai S, Iontophoretic pulsatile transdermal delivery of human parathyroid hormone (1-34). J Pharm Pharmacol 2001;53:1227-34
- Suzuki Y, Nagase Y, Iga K, Prevention of bone loss in ovariectomized rats by pulsatile transdermal iontophoretic administration of human PTH(1-34). J Pharm Sci 2002;91:350-61
- Bhatia KS, Singh J. Effect of dimethylacetamide and 2-pyrrolidone on the iontophoretic permeability of LHRH through porcine skin. Drug Dev Ind Pharm 1997;23:1215-18
- Bhatia KS, Gao S, Singh J. Effect of penetration enhancers and iontophoresis on the FT-IR spectroscopy and LHRH permeability through porcine skin. J Control Release 1997;47:81-9
- Bhatia KS, Singh J. Mechanism of transport enhancement of LHRH through porcine epidermis by terpenes and iontophoresis: permeability and lipid extraction studies. Pharm Res 1998;15:1857-62
- Bhatia KS, Singh J. Synergistic effect of iontophoresis and a series of fatty acids on LHRH permeability through porcine skin. J Pharm Sci 1998;87:462-9
- Bhatia KS, Singh J. Effect of linolenic acid ethanol or limonene ethanol and iontophoresis on the in vitro percutaneous absorption of LHRH and ultrastructure of human epidermis. Int J Pharm 1999;180:235-50
- Chen LLH, Chien YW. Transdermal iontophoretic permeation of luteinizing hormone releasing hormone: characterization of electric parameters. J Control Release 1996;40:187-98
- Heit MC, Monteiro-Riviere NA, Jayes FL, Riviere JE. Transdermal iontophoretic delivery of Luteinizing-Hormone-Releasing Hormone (LHRH) – Effect of repeated administration. Pharm Res 1994;11:1000-3
- Heit MC, Williams PL, Jayes FL, Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone. J Pharm Sci 1993;82:240-3
- Bayon AMR, Guy RH. Iontophoresis of nafarelin across human skin in vitro. Pharm Res 1996;13:798-800
- Meyer BR, Kreis W, Eschbach J, Successful transdermal administration of therapeutic doses of a polypeptide to normal human volunteers. Clin Pharmacol Ther 1988;44:607-12
- Meyer BR, Kreis W, Eschbach J, Transdermal versus subcutaneous leuprolide: a comparison of acute pharmacodynamic effect. Clin Pharmacol Ther 1990;48:340-5
- Miller LL, Kolaskie CJ, Smith GA, Rivier J. Transdermal iontophoresis of gonadotropin releasing hormone (LHRH) and two analogues. J Pharm Sci 1990;79:490-3
- Lelawongs P, Liu JC, Chien YW. Transdermal iontophoretic delivery of Arginine-Vasopressin. 2. Evaluation of electrical and operational factors. Int J Pharm 1990;61:179-88
- Banga AK, Katakam M, Mitra R. Transdermal iontophoretic delivery and degradation of Vasopressin across human cadaver skin. Int J Pharm 1995;116:211-16
- Nakakura M, Terajima M, Kato Y, Effect of iontophoretic patterns on in-vivo antidiuretic response to Desmopressin Acetate administered transdermally. J Drug Target 1995;2:487-92
- Nakakura M, Kato Y, Hayakawa E, Effect of pulse on iontophoretic delivery of desmopressin acetate in rats. Biol Pharm Bull 1996;19:738-40
- Nakakura M, Kato Y, Ito K. Prolongation of antidiuretic response to desmopressin acetate by iontophoretic transdermal delivery in rats. Biol Pharm Bull 1997;20:537-40
- Kumar S, Char H, Patel S, In vivo transdermal iontophoretic delivery of Growth-Hormone Releasing-Factor Grf (1-44) in hairless guinea-pigs. J Control Release 1992;18:213-20
- Ellens H, Lai ZP, Marcello J, Transdermal iontophoretic delivery of [H-3]GHRP in rats. Int J Pharm 1997;159:1-11
- Bushara KO, Park DM, Jones JC, Schutta HS. Botulinum toxin–a possible new treatment for axillary hyperhidrosis. Clin Exp Dermatol 1996;21:276-8
- Gregoriou S, Rigopoulos D, Makris M, Effects of botulinum toxin-A therapy for palmar hyperhidrosis in plantar sweat production. Dermatol Surg 2010;36:496-8
- Lowe NJ, Glaser DA, Eadie N, Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety. J Am Acad Dermatol 2007;56:604-11
- Schnider P, Binder M, Kittler H, A randomized, double-blind, placebo-controlled trial of botulinum A toxin for severe axillary hyperhidrosis. Br J Dermatol 1999;140:677-80
- Kavanagh GM, Oh C, Shams K. BOTOX (R) delivery by iontophoresis. Br J Dermatol 2004;151:1093-5
- Kavanagh GM, Shams K. Delivery of Botox (R) by iontophoresis: reply from authors. Br J Dermatol 2005;153:1076
- Woolery-Lloyd H, Elsaie ML, Avashia N. Inguinal hyperhidrosis misdiagnosed as urinary incontinence: treatment with botulinum toxin A. J Drugs Dermatol 2008;7:293-5
- Pacini S, Gulisano M, Punzi T, Ruggiero M. Transdermal delivery of Clostridium botulinum toxin type A by pulsed current iontophoresis. J Am Acad Dermatol 2007;57:1097-9
- Chang SL, Hofmann GA, Zhang L, The effect of electroporation on iontophoretic transdermal delivery of calcium regulating hormones. J Control Release 2000;66:127-33
- Medi BM, Singh J. Electronically facilitated transdermal delivery of human parathyroid hormone (1-34). Int J Pharm 2003;263:25-33
- Riviere JE, Monteiro-Riviere NA, Rogers RA, Pulsatile transdermal delivery of LHRH using electroporation. J Control Release 1995;36:229-33
- Badkar AV, Banga AK. Electrically enhanced transdermal delivery of a macromolecule. J Pharm Pharmacol 2002;54:907-12
- Smyth HD, Becket G, Mehta S. Effect of permeation enhancer pretreatment on the iontophoresis of luteinizing hormone releasing hormone (LHRH) through human epidermal membrane (HEM). J Pharm Sci 2002;91:1296-307
- Wu XM, Todo H, Sugibayashi K. Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis. J Control Release 2007;118:189-95
- Katikaneni S, Badkar A, Nema S, Banga AK. Molecular charge mediated transport of a 13 kD protein across microporated skin. Int J Pharm 2009;378:93-100
- Katikaneni S, Li G, Badkar A, Banga AK. Transdermal delivery of a approximately 13 kDa protein--an in vivo comparison of physical enhancement methods. J Drug Target 2010;18:141-7
- Badkar AV, Smith AM, Eppstein JA, Banga AK. Transdermal delivery of interferon alpha-2B using microporation and iontophoresis in hairless rats. Pharm Res 2007;24:1389-95