1,027
Views
102
CrossRef citations to date
0
Altmetric
Reviews

Contact lenses as a platform for ocular drug delivery

, , &
Pages 1483-1496 | Published online: 22 Jul 2013

Bibliography

  • Lang JC. Ocular drug delivery conventional ocular formulations. Adv Drug Deliv Rev 1995;16(1):39-43
  • Gaudana R, Ananthula HK, Parenky A, Mitra AK. Ocular drug delivery. AAPS J 2010;12(3):348-60
  • Larke JR. Tears. In: Larke JR, editor, The eye in contact lens wear. 2nd edition. Butterworth Heinemann, Oxford, Boston; 1997. p. 30
  • Watsky MA, Jablonski MM, Edelhauser HF. Comparison of conjunctival and corneal surface areas in rabbit and human. Curr Eye Res 1988;7(5):483-6
  • Prausnitz MR, Noonan JS. Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye. J Pharm Sci 1998;87(12):1479-88
  • Salminen L. Review: systemic absorption of topically applied ocular drugs in humans. J Ocul Pharmacol 1990;6(3):243-9
  • Gray C. Systemic toxicity with topical ophthalmic medications in children. Paediatr Perinat Drug Ther 2006;7(1):23-9
  • Jaanus SD. Anti-inflammatory agents. In: Bartlett JD, editor. Ophthalmic drug facts. Wolters Kluwer Health, Inc, St. Louis, Missouri, USA; 2005. p. 93
  • Gahl WA, Kuehl EM, Iwata F, et al. Corneal crystals in nephropathic cystinosis: natural history and treatment with cysteamine eyedrops. Mol Genet Metab 2000;71(1-2):100-20
  • Chrai SS, Makoid MC, Eriksen SP, Robinson JR. Drop size and initial dosing frequency problems of topically applied ophthalmic drugs. J Pharm Sci 1974;63(3):333-8
  • Fechtner RD, Realini T. Fixed combinations of topical glaucoma medications. Curr Opin Ophthalmol 2004;15(2):132-5
  • Prescribing information for CYSTARAN™. Sigma-Tau Pharmaceuticals, Inc. Available from: http://www.sigmatau.com/products/CYSTARANPI.pdf [Last accessed 16 May 2013]
  • Bourlais CL, Acar L, Zia H, et al. Ophthalmic drug delivery systems–recent advances. Prog Retin Eye Res 1998;17(1):33-58
  • Ghate D, Edelhauser HF. Ocular drug delivery. Expert Opin Drug Deliv 2006;3(2):275-87
  • Kuno N, Fujii S. Recent advances in ocular drug delivery systems. Polymers 2011;3(4):193-221
  • Al-Kinani AA, Calabrese G, Vangala A, et al. Nanotechnology in ophthalmic drug delivery. In: Souto EB, editor. Patenting nanomedicines. Springer-Verlag; Berlin Heidelberg: 2012. p. 277-303
  • Eljarrat-Binstock E, Domb AJ. Iontophoresis: a non-invasive ocular drug delivery. J Control Release 2006;110(3):479-89
  • Jiang J, Gill HS, Ghate D, et al. Coated microneedles for drug delivery to the eye. Invest Ophthalmol Vis Sci 2007;48(9):4038-43
  • King-Smith PE, Fink BA, Hill RM, et al. The thickness of the tear film. Curr Eye Res 2004;29(4-5):357-68
  • Li C, Chauhan A. Modeling ophthalmic drug delivery by soaked contact lenses. Ind Eng Chem Res 2006;45(10):3718-34
  • Wichterle O, Lím D. Hydrophilic gels for biological use. Nature 1960;185(4706):117-18
  • Sedlacek J. Possibility of the application of ophthalmic drugs with the use of gel contact lenses. Cesk Oftalmol 1965;21(6):509-12
  • Waltman SR, Kaufman HE. Use of hydrophilic contact lenses to increase ocular penetration of topical drugs. Invest Ophthalmol 1970;9(4):250-5
  • Hillman JS. Management of acute glaucoma with pilocarpine-soaked hydrophilic lens. Br J Ophthalmol 1974;58(7):674-9
  • Jain MR, Batra V. Steroid pentetration in human aqueous with ‘sauflon 70' lenses. Indian J Ophthalmol 1979;27:26-31
  • Jain MR. Drug delivery through soft contact lenses. Br J Ophthalmol 1988;72(2):150-4
  • Hehl EM, Beck R, Luthard K, et al. Improved penetration of aminoglycosides and fluorozuinolones into the aqueous humour of patients by means of acuvue contact lenses. Eur J Clin Pharmacol 1999;55(4):317-23
  • Tian X, Iwatsu M, Kanai A. Disposable 1-day acuvue contact lenses for the delivery of lomefloxacin to rabbits' eyes. CLAO J 2001;27(4):212-15
  • Mindel JS, Smith H, Jacobs M, et al. Drug reservoirs in topical therapy. Invest Ophthalmol Vis Sci 1984;25(3):346-50
  • Sieg JW, Robinson JR. Mechanistic studies on transcorneal permeation of pilocarpine. J Pharm Sc 1976;65(12):1816-22
  • Maurice DM. Structure and fluids invovled in the penetration of topically applied drugs. Int Ophthalmol Clin 1980;20(3):7-20
  • Karlgard CC, Jones LW, Moresoli C. Ciprofloxacin interaction with silicon-based and conventional hydrogel contact lenses. Eye Contact Lens 2003;29(2):83-9
  • Karlgard CC, Wong NS, Jones LW, Moresoli C. In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials. Int J Pharm 2003;257(1-2):141-51
  • Hui A, Boone A, Jones L. Uptake and release of ciprofloxacin-HCl from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 2008;34(5):266-71
  • Schultz CL, Poling TR, Mint JO. A medical device/drug delivery system for treatment of glaucoma. Clin Exp Optom 2009;92(4):343-8
  • Soluri A, Hui A, Jones L. Delivery of ketotifen fumarate by commercial contact lens materials. Optom Vis Sci 2012;89(8):1140-9
  • Boone A, Hui A, Jones L. Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses. Eye Contact Lens 2009;35(5):260-7
  • Peng C, Kim J, Chauhan A. Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing vitamin E diffusion barriers. Biomaterials 2010;31(14):4032-47
  • Kim J, Peng C, Chauhan A. Extended release of dexamethasone from silicone-hydrogel contact lenses containing vitamin E. J Control Release 2010;148(1):110-16
  • Peng C, Chauhan A. Extended cyclosporine delivery by silicone–hydrogel contact lenses. J Control Release 2011;154(3):267-74
  • Peng C, Burke MT, Chauhan A. Transport of topical anesthetics in vitamin E loaded silicone hydrogel contact lenses. Langmuir 2011;28(2):1478-87
  • Peng C, Ben-Shlomo A, Mackay EO, et al. Drug delivery by contact lens in spontaneously glaucomatous dogs. Curr Eye Res 2012;37(3):204-11
  • Peng C, Burke MT, Carbia BE, et al. Extended drug delivery by contact lenses for glaucoma therapy. J Control Release 2012;162:152-8
  • Byrne ME, Park K, Peppas NA. Molecular imprinting within hydrogels. Adv Drug Deliv Rev 2002;54(1):149-61
  • Alvarez-Lorenzo C, Concheiro A. Molecularly imprinted polymers for drug delivery. J Chromatography B 2004;804(1):231-45
  • Sellergren B, Allender CJ. Molecularly imprinted polymers: a bridge to advanced drug delivery. Adv Drug Deliv Rev 2005;57(12):1733-41
  • Cunliffe D, Kirby A, Alexander C. Molecularly imprinted drug delivery systems. Adv Drug Deliv Rev 2005;57(12):1836-53
  • Xinming L, Yingde C, Lloyd AW, et al. Polymeric hydrogels for novel contact lens-based ophthalmic drug delivery systems: a review. Contact Lens Ant Eye 2008;31(2):57-64
  • Byrne ME, Salian V. Molecular imprinting within hydrogels II: Progress and analysis of the field. Int J Pharm 2008;364(2):188-212
  • Kryscio DR, Peppas NA. Critical review and perspective of macromolecularly imprinted polymers. Acta Biomater 2012;8(2):461-73
  • Hiratani H, Alvarez-Lorenzo C. Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid. J Control Release 2002;83(2):223-30
  • Alvarez-Lorenzo C, Yañez F, Barreiro-Iglesias R, Concheiro A. Imprinted soft contact lenses as norfloxacin delivery systems. J Control Release 2006;113(3):236-44
  • Ali M, Horikawa S, Venkatesh S, et al. Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow. J Control Release 2007;124(3):154-62
  • Ali M, Byrne ME. Controlled release of high molecular weight hyaluronic acid from molecularly imprinted hydrogel contact lenses. Pharm Res 2009;26(3):714-26
  • Yañez F, Chauhan A, Concheiro A, Alvarez Lorenzo C. Timolol imprinted soft contact lenses: Influence of the template: Functional monomer ratio and the hydrogel thickness. J Appl Polym Sci 2011;122(2):1333-40
  • White CJ, McBride MK, Pate KM, et al. Extended release of high molecular weight hydroxypropyl methylcellulose from molecularly imprinted, extended wear silicone hydrogel contact lenses. Biomaterials 2011;32(24):5698-705
  • Malaekeh Nikouei B, Ghaeni FA, Motamedshariaty VS, Mohajeri SA. Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses. J Appl Polym Sci 2012;126(1):387-94
  • Venkatesh S, Saha J, Pass S, Byrne ME. Transport and structural analysis of molecular imprinted hydrogels for controlled drug delivery. Eur J Pharm Biopharm 2008;69(3):852-60
  • Karlsson BC, O'Mahony J, Karlsson JG, et al. Structure and dynamics of monomer− template complexation: An explanation for molecularly imprinted polymer recognition site heterogeneity. J Am Chem Soc 2009;131(37):13297-304
  • Nicholls IA, Andersson HS, Golker K, et al. Rational design of biomimetic molecularly imprinted materials: theoretical and computational strategies for guiding nanoscale structured polymer development. Anal Bioanal Chem 2011;400(6):1771-86
  • Hiratani H, Alvarez-Lorenzo C. The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems. Biomaterials 2004;25(6):1105-13
  • Hiratani H, Fujiwara A, Tamiya Y, et al. Ocular release of timolol from molecularly imprinted soft contact lenses. Biomaterials 2005;26(11):1293-8
  • Venkatesh S, Sizemore SP, Byrne ME. Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics. Biomaterials 2007;28(4):717-24
  • Yañez F, Martikainen L, Braga ME, et al. Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery. Acta Biomater 2011;7(3):1019-30
  • Costa VP, Braga MEM, Guerra JP, et al. Development of therapeutic contact lenses using a supercritical solvent impregnation method. J Supercrit Fluid 2010;52(3):306-16
  • Costa VP, Braga MEM, Duarte CMM, et al. Anti-glaucoma drug-loaded contact lenses prepared using supercritical solvent impregnation. J Supercrit Fluid 2010;53(1-3):165-73
  • Tieppo A, White C, Paine A, et al. Sustained in vivo release from imprinted therapeutic contact lenses. J Controll Release 2012;157(3):391-7
  • Gulsen D, Li C, Chauhan A. Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery. Curr Eye Res 2005;30(12):1071-80
  • Danion A, Brochu H, Martin Y, Vermette P. Fabrication and characterization of contact lenses bearing surface-immobilized layers of intact liposomes. J Biomed Mater Res A 2007;82(1):41-51
  • Gulsen D, Chauhan A. Ophthalmic drug delivery through contact lenses. Invest Ophthalmol Vis Sci 2004;45(7):2342-7
  • Gulsen D, Chauhan A. Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle. Int J Pharm 2005;292(1–2):95-117
  • Ferreira JA, Oliveira PD, Silva PMD, et al. Sustained drug released from contact lens. 2009. Pré-Publicações DMUC Available from: http://hdl.handle.net/10316/11167 [Last accessed 16 May 2013]
  • Jung HJ, Chauhan A. Temperature sensitive contact lenses for triggered ophthalmic drug delivery. Biomaterials 2012;33(7):2289-300
  • Garhwal R, Shady SF, Ellis EJ, et al. Sustained ocular delivery of ciprofloxacin using nanospheres and conventional contact lens materials. Invest Ophthalmol Vis Sci 2012;53(3):1341-52
  • Lu C, Yoganathan RB, Kociolek M, Allen C. Hydrogel containing silica shell cross-linked micelles for ocular drug delivery. J Pharm Sci 2013;102(2):627-37
  • Kapoor Y, Chauhan A. Drug and surfactant transport in cyclosporine A and brij 98 laden p-HEMA hydrogels. J Colloid Interface Sci 2008;322(2):624-33
  • Kapoor Y, Thomas JC, Tan G, et al. Surfactant-laden soft contact lenses for extended delivery of ophthalmic drugs. Biomaterials 2009;30(5):867-78
  • Uchida R, Sato T, Tanigawa H, Uno K. Azulene incorporation and release by hydrogel containing methacrylamide propyltrimenthylammonium chloride, and its application to soft contact lens. J Control Release 2003;92(3):259-64
  • Sato T, Uchida R, Tanigawa H, et al. Application of polymer gels containing side-chain phosphate groups to drug-delivery contact lenses. J Appl Polym Sci 2005;98(2):731-5
  • Yamazaki Y, Matsunaga T, Syohji K, et al. Effect of anionic/siloxy groups on the release of ofloxacin from soft contact lenses. J Appl Polym Sci 2013;127(6):5022-7
  • Kakisu K, Matsunaga T, Kobayakawa S, et al. Development and efficacy of a drug-releasing soft contact lens. Invest Ophthalmol Vis Sci 2013;54(4):2551-61
  • Xu J, Li X, Sun F. Preparation and evaluation of a contact lens vehicle for puerarin delivery. J Biomat Sci Polym E 2010;21(3):271-88
  • Bengani LC, Chauhan A. Extended delivery of an anionic drug by contact lens loaded with a cationic surfactant. Biomaterials 2013;34(11):2814-21
  • Kim J, Conway A, Chauhan A. Extended delivery of ophthalmic drugs by silicone hydrogel contact lenses. Biomaterials 2008;29(14):2259-69
  • Xu J, Li X, Sun F. Cyclodextrin-containing hydrogels for contact lenses as a platform for drug incorporation and release. Acta Biomater 2010;6(2):486-93
  • Rosa dos Santos J, Alvarez-Lorenzo C, Silva M, et al. Soft contact lenses functionalized with pendant cyclodextrins for controlled drug delivery. Biomaterials 2009;30(7):1348-55
  • Mullarney MP, Seery TAP, Weiss RA. Drug diffusion in hydrophobically modified N,N-dimethylacrylamide hydrogels Polymer. 2006;47(11):3845-55
  • Ciolino JB, Hoare TR, Iwata NG, et al. A drug-eluting contact lens. Invest Ophthalmol Vis Sci 2009;50(7):33467-52
  • Ciolino JB, Hudson SP, Mobbs AN, et al. A prototype antifungal contact lens. Invest Ophthalmol Vis Sci 2011;52(9):6286-91
  • Chauhan A, Gulsen D. Ophthalmic drug delivery system. US7638137; 2009
  • Chauhan A, Gulsen D, Kapoor Y, Li C-C. Dispersions of microemulsions in hydrogels for drug delivery. US8071121; 2011
  • Dean-Mo L, Pei-Ling L. Drug-carrying contact lens and method for fabricating the same. US20130011460A1; 2013
  • Joseph JB Jr, Hoare TR, Kohane DS. Contact lens drug delivery device. US8414912; 2013
  • Ali M, Byrne ME. Controlled and extended delivery of hyaluronic acid and comfort molecules via a contact lens platform. US8388995; 2013
  • Chauhan A, Kim J. Contact lenses for extended release of bioactive agents containing diffusion attenuators. US8404265; 2013
  • Safety study of a contact lens wtih ketotifen in healthy, normal volunteers, Vistakon Pharmaceuticals at ClinicalTrials.gov. 2011. Available from: http://clinicaltrials.gov/ct2/show/NCT00889252 [Last accessed 16 May 2013]
  • Hiratani H, Mizutani Y, Alvarez Lorenzo C. Controlling drug release from imprinted hydrogels by modifying the characteristics of the imprinted cavities. Macromol Biosci 2005;5(8):728-33
  • Andrade Vivero P, FernandezGabriel E, Alvarez Lorenzo C, Concheiro A. Improving the loading and release of NSAIDs from pHEMA hydrogels by copolymerization with functionalized monomers. J Pharm Sci 2007;96(4):802-13
  • Ribeiro A, Veiga F, Santos D, et al. Bioinspired imprinted PHEMA-hydrogels for ocular delivery of carbonic anhydrase inhibitor drugs. Biomacromolecules 2011;12(3):701-9
  • Ribeiro A, Veiga F, Santos D, et al. Receptor-based biomimetic NVP/DMA contact lenses for loading/eluting carbonic anhydrase inhibitors. J Membr Sci 2011;383(1):60-9
  • Tieppo A, Pate KM, Byrne ME. In vitro controlled release of an anti-inflammatory from daily disposable therapeutic contact lenses under physiological ocular tear flow. Eur J Pharm Biopharm 2012;81(1):170-7
  • Hui A, Sheardown H, Jones L. Acetic and acrylic acid molecular imprinted model silicone hydrogel materials for ciprofloxacin-HCl delivery. Materials 2012;5(1):85-107

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.