Drug delivery systems for intra-articular treatment of osteoarthritis

Bibliography

• Caldwell JR. Intra-articular corticosteroids. Guide to selection and indications for use. Drugs 1996;52:507-14
   PubMed Web of Science ®Google Scholar
• Nagerl H, Kubein-Meesenburg D, Cotta H, et al. Biomechanical principles of diarthroses and synarthroses. III: mechanical aspects of the tibiofemoral joint and role of the cruciate ligaments. Z Orthop Ihre Grenzgeb 1993;131:385-96
   PubMedGoogle Scholar
• Levick JR, McDonald JN. Fluid movement across synovium in healthy joints: role of synovial fluid macromolecules. Ann Rheum Dis 1995;54:417-23
   PubMed Web of Science ®Google Scholar
• Werner CM, Nyffeler RW, Jacob HA, et al. The effect of capsular tightening on humeral head translations. J Orthop Res 2004;22:194-201
   PubMed Web of Science ®Google Scholar
• Pieper KS, Fehrmann P, Vergani G, et al. On the functional organisation of hyaline articular cartilage. Ital J Anat Embryol 1995;100(Suppl 1):113-19
   PubMedGoogle Scholar
• Wilkinson LS, Pitsillides AA, Worrall JG, et al. Light microscopic characterization of the fibroblast-like synovial intimal cell (synoviocyte). Arthritis Rheum 1992;35:1179-84
   PubMed Web of Science ®Google Scholar
• Senda H, Sakuma E, Wada I, et al. Ultrastructural study of cells at the synovium-cartilage junction: response of synovial cells of the rat knee joint to intra-articularly injected latex particles. Kaibogaku Zasshi 1999;74:525-35
   PubMedGoogle Scholar
• Wallis WJ, Simkin PA. Antirheumatic drug concentrations in human synovial fluid and synovial tissue. Observations on extravascular pharmacokinetics. Clin Pharmacokinet 1983;8:496-522
   PubMed Web of Science ®Google Scholar
• van der Kraan PM, Buma P, van Kuppevelt T, et al. Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering. Osteoarthritis Cartilage 2002;10:631-7
   PubMed Web of Science ®Google Scholar
• van der Kraan PM, van den Berg WB. Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration? Osteoarthritis Cartilage 2012;20:223-32
   PubMed Web of Science ®Google Scholar
• Goldring MB. The role of the chondrocyte in osteoarthritis. Arthritis Rheum 2000;43:1916-26
   PubMed Web of Science ®Google Scholar
• Sarzi-Puttini P, Cimmino MA, Scarpa R, et al. Osteoarthritis: an overview of the disease and its treatment strategies. Semin Arthritis Rheum 2005;35:1-10
   PubMed Web of Science ®Google Scholar
• Swiechowicz S, Ostalowska A, Kasperczyk A, et al. Evaluation of hyaluronic acid intra-articular injections in the treatment of primary and secondary osteoarthritis of the knee. Pol Orthop Traumatol 2012;77:105-9
   Google Scholar
• Flood J. The role of acetaminophen in the treatment of osteoarthritis. Am J Manag Care 2010;16(Suppl Management):S48-54
   PubMedGoogle Scholar
• Chen YF, Jobanputra P, Barton P, et al. Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. Health Technol Assess 2008;12:1-278
   PubMed Web of Science ®Google Scholar
• Qvist P, Bay-Jensen AC, Christiansen C, et al. The disease modifying osteoarthritis drug (DMOAD): is it in the horizon? Pharmacol Res 2008;58:1-7
   PubMed Web of Science ®Google Scholar
• Richmond JC. Surgery for osteoarthritis of the knee. Rheum Dis Clin North Am 2013;39:203-11
   PubMed Web of Science ®Google Scholar
• Larsen C, Ostergaard J, Larsen SW, et al. Intra-articular depot formulation principles: role in the management of postoperative pain and arthritic disorders. J Pharm Sci 2008;97:4622-54
   PubMed Web of Science ®Google Scholar
• Abramson S. Drug delivery in degenerative joint disease: where we are and where to go? Adv Drug Deliv Rev 2006;58:125-7
   PubMed Web of Science ®Google Scholar
• Neander G, Eriksson LO, Wallin-Boll E, et al. Pharmacokinetics of intraarticular indomethacin in patients with osteoarthritis. Eur J Clin Pharmacol 1992;42:301-5
   PubMed Web of Science ®Google Scholar
• Gerwin N, Hops C, Lucke A. Intraarticular drug delivery in osteoarthritis. Adv Drug Deliv Rev 2006;58:226-42
   PubMed Web of Science ®Google Scholar
• Owen SG, Francis HW, Roberts MS. Disappearance kinetics of solutes from synovial fluid after intra-articular injection. Br J Clin Pharmacol 1994;38:349-55
   PubMed Web of Science ®Google Scholar
• Coleman PJ, Scott D, Ray J, et al. Hyaluronan secretion into the synovial cavity of rabbit knees and comparison with albumin turnover. J Physiol 1997;503:645-56
   PubMed Web of Science ®Google Scholar
• Bergsma JE, de Bruijn WC, Rozema FR, et al. Late degradation tissue response to poly(L-lactide) bone plates and screws. Biomaterials 1995;16:25-31
   PubMed Web of Science ®Google Scholar
• Williams DF. The Williams dictionary of biomaterials. Liverpool University Press; Liverpool: UK: 1999
   Google Scholar
• Williams DF. On the mechanisms of biocompatibility. Biomaterials 2008;29:2941-53
   PubMed Web of Science ®Google Scholar
• Raynauld JP, Buckland-Wright C, Ward R, et al. Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2003;48:370-7
   PubMed Web of Science ®Google Scholar
• Neustadt DH. Intra-articular injections for osteoarthritis of the knee. Cleve Clin J Med 2006;73:897-8
   PubMed Web of Science ®Google Scholar
• Saxne T, Heinegard D, Wollheim FA, et al. Therapeutic effects on cartilage metabolism in arthritis as measured by release of proteoglycan structures into the synovial fluid. Ann Rheum Dis 1986;45:491-7
   PubMed Web of Science ®Google Scholar
• Hepper CT, Halvorson JJ, Duncan ST, et al. The efficacy and duration of intra-articular corticosteroid injection for knee osteoarthritis: a systematic review of level I studies. J Am Acad Orthop Surg 2009;17:638-46
   PubMed Web of Science ®Google Scholar
• Arroll B, Goodyear-Smith F. Corticosteroid injections for osteoarthritis of the knee: meta-analysis. BMJ 2004;328:869
   PubMed Web of Science ®Google Scholar
• Raynauld JP, Buckland-Wright C, Ward R, et al. Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2003;48:370-7
   PubMed Web of Science ®Google Scholar
• Balazs EA, Watson D, Duff IF, et al. Hyaluronic acid in synovial fluid. I. Molecular parameters of hyaluronic acid in normal and arthritis human fluids. Arthritis Rheum 1967;10:357-76
   PubMed Web of Science ®Google Scholar
• Rydell N, Balazs EA. Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of osteoarthritis and on granulation tissue formation. Clin Orthop Relat Res 1971;80:25-32
   PubMedGoogle Scholar
• Listrat V, Ayral X, Patarnello F, et al. Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthritis Cartilage 1997;5:153-60
   PubMed Web of Science ®Google Scholar
• Jones AC, Pattrick M, Doherty S, et al. Intra-articular hyaluronic acid compared to intra-articular triamcinolone hexacetonide in inflammatory knee osteoarthritis. Osteoarthritis Cartilage 1995;3:269-73
   PubMed Web of Science ®Google Scholar
• Leopold SS, Redd BB, Warme WJ, et al. Corticosteroid compared with hyaluronic acid injections for the treatment of osteoarthritis of the knee. A prospective, randomized trial. J Bone Joint Surg Am 2003;85-A:1197-203
   PubMedGoogle Scholar
• American Academy of Orthopedic Surgeons. Treatment of Osteoarthritis of the Knee. 2013 Annual Meeting; Rosemont, IL, USA
   Google Scholar
• Brandt KD, Smith GN Jr, Simon LS. Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: what is the evidence? Arthritis Rheum 2000;43:1192-203
   PubMed Web of Science ®Google Scholar
• Chen WD, Jiang Q, Chen DY, et al. Effects of intra-articular injection of p38 mitogen-activated protein kinase inhibitor on matrix metalloproteinase in articular cartilage of a rat model of osteoarthritis. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007;29:777-81
   PubMedGoogle Scholar
• Gege C BB, Bluhm H, Boer J, et al. Discovery and evaluation of a anterior cruciate ligament transection) inhibitor for potential intra-articular treatment of osteoarthritis. J Med Chem 2012;55:709-916
   PubMed Web of Science ®Google Scholar
• Filardo G, Kon E. PRP: more words than facts. Knee Surg Sports Traumatol Arthrosc 2012;20:1655-6
   PubMed Web of Science ®Google Scholar
• Smyth SS, McEver RP, Weyrich AS, et al. Platelet functions beyond hemostasis. J Thromb Haemost 2009;7:1759-66
   PubMed Web of Science ®Google Scholar
• Foster TE, Brooks JR. Functional groups based on leaf physiology: are they spatially and temporally robust? Oecologia 2005;144:337-52
   PubMed Web of Science ®Google Scholar
• Anitua E, Andia I, Ardanza B, et al. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004;91:4-15
   PubMed Web of Science ®Google Scholar
• Mifune Y, Matsumoto T, Takayama K, et al. The effect of platelet-rich plasma on the regenerative therapy of muscle derived stem cells for articular cartilage repair. Osteoarthritis Cartilage 2013;21:175-85
   PubMed Web of Science ®Google Scholar
• Kwon DR, Park GY, Lee SU. The effects of intra-articular platelet-rich plasma injection according to the severity of collagenase-induced knee osteoarthritis in a rabbit model. Ann Rehabil Med 2012;36:458-65
   PubMedGoogle Scholar
• Saito M, Takahashi KA, Arai Y, et al. Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the rabbit knee. Clin Exp Rheumatol 2009;27:201-7
   PubMed Web of Science ®Google Scholar
• Patel S, Dhillon MS, Aggarwal S, et al. Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial. Am J Sports Med 2013;41:356-64
   PubMed Web of Science ®Google Scholar
• Cerza F, Carni S, Carcangiu A, et al. Comparison between hyaluronic acid and platelet-rich plasma, intra-articular infiltration in the treatment of gonarthrosis. Am J Sports Med 2012;40:2822-7
   PubMed Web of Science ®Google Scholar
• Spakova T, Rosocha J, Lacko M, et al. Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid. Am J Phys Med Rehabil 2012;91:411-17
   PubMed Web of Science ®Google Scholar
• Say F, Gurler D, Yener K, et al. Platelet-Rich Plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis. Acta Chir Orthop Traumatol Cech 2013;80:278-83
   PubMed Web of Science ®Google Scholar
• Kon E, Mandelbaum B, Buda R, et al. Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis. Arthroscopy 2011;27:1490-501
   PubMed Web of Science ®Google Scholar
• Jang SJ, Kim JD, Cha SS. Platelet-rich plasma (PRP) injections as an effective treatment for early osteoarthritis. Eur J Orthop Surg Traumatol 2013;23:573-80
   PubMedGoogle Scholar
• Kato Y, Iwamoto M, Koike T. Fibroblast growth factor stimulates colony formation of differentiated chondrocytes in soft agar. J Cell Physiol 1987;133:491-8
   PubMed Web of Science ®Google Scholar
• Yamamoto T, Wakitani S, Imoto K, et al. Fibroblast growth factor-2 promotes the repair of partial thickness defects of articular cartilage in immature rabbits but not in mature rabbits. Osteoarthritis Cartilage 2004;12:636-41
   PubMed Web of Science ®Google Scholar
• Kawaguchi H, Kurokawa T, Hanada K, et al. Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats. Endocrinology 1994;135:774-81
   PubMed Web of Science ®Google Scholar
• Sah RL, Chen AC, Grodzinsky AJ, et al. Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys 1994;308:137-47
   PubMed Web of Science ®Google Scholar
• Inoue A, Takahashi KA, Arai Y, et al. The therapeutic effects of basic fibroblast growth factor contained in gelatin hydrogel microspheres on experimental osteoarthritis in the rabbit knee. Arthritis Rheum 2006;54:264-70
   PubMed Web of Science ®Google Scholar
• Mierisch CM, Cohen SB, Jordan LC, et al. Transforming growth factor-beta in calcium alginate beads for the treatment of articular cartilage defects in the rabbit. Arthroscopy 2002;18:892-900
   PubMed Web of Science ®Google Scholar
• Rowely J MG, Mooney D. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999;20:45-53
   PubMed Web of Science ®Google Scholar
• Zhang Z, Huang G. Intra-articular lornoxicam loaded PLGA microspheres: enhanced therapeutic efficiency and decreased systemic toxicity in the treatment of osteoarthritis. Drug Deliv 2012;19:255-63
   PubMed Web of Science ®Google Scholar
• Eswaramoorthy R, Chang CC, Wu SC, et al. Sustained release of PTH(1-34) from PLGA microspheres suppresses osteoarthritis progression in rats. Acta Biomater 2012;8:2254-62
   PubMed Web of Science ®Google Scholar
• Ko JY, Choi YJ, Jeong GJ, et al. Sulforaphane-PLGA microspheres for the intra-articular treatment of osteoarthritis. Biomaterials 2013;34:5359-68
   PubMed Web of Science ®Google Scholar
• Bodick N, Lufkin J, Willwerth C, et al. FX006 Prolongs the Residency of Triamcinolone Acetonide in the Synovial Tissues of Patients with Knee Osteoarthritis. Osteoarthritis Cartilage 2013;21(Suppl):s144-5
   PubMedGoogle Scholar
• Rawal N, Kroner K, Simin-Geertsen M, et al. Safety of lornoxicam in the treatment of postoperative pain: a post-marketing study of analgesic regimens containing lornoxicam compared with standard analgesic treatment in 3752 day-case surgery patients. Clin Drug Investig 2010;30:687-97
   PubMed Web of Science ®Google Scholar
• Balfour JA, Fitton A, Barradell LB. Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs 1996;51:639-57
   PubMed Web of Science ®Google Scholar
• Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 2007;64:1105-27
   PubMed Web of Science ®Google Scholar
• Heiss E, Herhaus C, Klimo K, et al. Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. J Biol Chem 2001;276:32008-15
   PubMed Web of Science ®Google Scholar
• Cai L, Okumu FW, Cleland JL, et al. A slow release formulation of insulin as a treatment for osteoarthritis. Osteoarthritis Cartilage 2002;10:692-706
   PubMed Web of Science ®Google Scholar
• Chang JK, Chang LH, Hung SH, et al. Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats. Arthritis Rheum 2009;60:3049-60
   PubMed Web of Science ®Google Scholar
• Yoshioka T, Kawazoe N, Tateishi T, et al. In vitro evaluation of biodegradation of poly(lactic-coglycolic acid) sponges. Biomaterials 2008;29:3438-43
   PubMed Web of Science ®Google Scholar
• Yang Y, Tang G, Zhao Y, et al. Effect of cyclic loading on in vitro degradation of poly(L-lactide-co-glycolide) scaffolds. J Biomater Sci Polym Ed 2010;21:53-66
   PubMed Web of Science ®Google Scholar
• Elron-Gross I, Glucksam Y, Margalit R. Liposomal dexamethasone-diclofenac combinations for local osteoarthritis treatment. Int J Pharm 2009;376:84-91
   PubMed Web of Science ®Google Scholar
• Dong J, Jiang D, Wang Z, et al. Intra-articular delivery of liposomal celecoxib-hyaluronate combination for the treatment of osteoarthritis in rabbit model. Int J Pharm 2013;441:285-90
   PubMed Web of Science ®Google Scholar
• Clemett D, Goa KL. Celecoxib: a review of its use in osteoarthritis, rheumatoid arthritis and acute pain. Drugs 2000;59:957-80
   PubMed Web of Science ®Google Scholar
• Solomon SD, McMurray JJ, Pfeffer MA, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005;352:1071-80
   PubMed Web of Science ®Google Scholar
• Deniz A, Sade A, Severcan F, et al. Celecoxib-loaded liposomes: effect of cholesterol on encapsulation and in vitro release characteristics. Biosci Rep 2010;30:365-73
   PubMed Web of Science ®Google Scholar
• Foradada M, Pujol MD, Bermudez J, et al. Chemical degradation of liposomes by serum components detected by NMR. Chem Phys Lipids 2000;104:133-48
   PubMed Web of Science ®Google Scholar
• Davidsen J, Jorgensen K, Andresen TL, et al. Secreted phospholipase A(2) as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue. Biochim Biophys Acta 2003;1609:95-101
   PubMed Web of Science ®Google Scholar
• Elron-Gross I, Glucksam Y, Biton IE, et al. A novel Diclofenac-carrier for local treatment of osteoarthritis applying live-animal MRI. J Control Release 2009;135:65-70
   PubMed Web of Science ®Google Scholar
• Srinivasan PP, McCoy SY, Jha AK, et al. Injectable perlecan domain 1-hyaluronan microgels potentiate the cartilage repair effect of BMP2 in a murine model of early osteoarthritis. Biomed Mater 2012;7:024109
   PubMed Web of Science ®Google Scholar
• Blaney Davidson EN, Vitters EL, van Lent PL, et al. Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling. Arthritis Res Ther 2007;9:R102
   PubMedGoogle Scholar
• Dell'Accio F, De Bari C, El Tawil NM, et al. Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury. Arthritis Res Ther 2006;8:R139
   PubMed Web of Science ®Google Scholar
• Ruppert R, Hoffmann E, Sebald W. Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity. Eur J Biochem 1996;237:295-302
   PubMedGoogle Scholar
• Yang W, Gomes RR, Brown AJ, et al. Chondrogenic differentiation on perlecan domain I, collagen II, and bone morphogenetic protein-2-based matrices. Tissue Eng 2006;12:2009-24
   Google Scholar
• Mio K, Stern R. Inhibitors of the hyaluronidases. Matrix Biol 2002;21:31-7
   PubMed Web of Science ®Google Scholar
• Chen WY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen 1999;7:79-89
   PubMed Web of Science ®Google Scholar
• Petrak K. Essential properties of drug-targeting delivery systems. Drug Discov Today 2005;10:1667-73
   PubMed Web of Science ®Google Scholar
• Whitmire RE, Wilson DS, Singh A, et al. Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins. Biomaterials 2012;33:7665-75
   PubMed Web of Science ®Google Scholar
• Rothenfluh DA, Bermudez H, O'Neil CP, et al. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage. Nat Mater 2008;7:248-54
   PubMed Web of Science ®Google Scholar
• Zille H, Paquet J, Henrionnet C, et al. Evaluation of intra-articular delivery of hyaluronic acid functionalized biopolymeric nanoparticles in healthy rat knees. Biomed Mater Eng 2010;20:235-42
   PubMed Web of Science ®Google Scholar
• Laroui H, Grossin L, Leonard M, et al. Hyaluronate-covered nanoparticles for the therapeutic targeting of cartilage. Biomacromolecules 2007;8:3879-85
   PubMed Web of Science ®Google Scholar
• Mark A, Ward TKG. Thermoresponsive polymers for biomedical applications. Polymers 2011;3:1215-42
   Google Scholar
• Urry DW. Physical chemistry of biological free energy transduction as demonstrated by elastic protein-based polymers. J Phys Chem 1997;B 101:11007-28
   Web of Science ®Google Scholar
• Betre H, Liu W, Zalutsky MR, et al. A thermally responsive biopolymer for intra-articular drug delivery. J Control Release 2006;115:175-82
   PubMed Web of Science ®Google Scholar
• Caron JP, Fernandes JC, Martel-Pelletier J, et al. Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression. Arthritis Rheum 1996;39:1535-44
   PubMed Web of Science ®Google Scholar
• Bresnihan B, Cobby M. Clinical and radiological effects of anakinra in patients with rheumatoid arthritis. Rheumatology (Oxford) 2003;42(Suppl 2):ii22-8
   PubMedGoogle Scholar
• Evans CH, Gouze JN, Gouze E, et al. Osteoarthritis gene therapy. Gene Ther 2004;11:379-89
   PubMed Web of Science ®Google Scholar
• Chevalier X, Giraudeau B, Conrozier T, et al. Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study. J Rheumatol 2005;32:1317-23
   PubMed Web of Science ®Google Scholar
• Shamji MF, Betre H, Chen J, et al. Development of a thermally responsive drug depot for intra-articular delivery of interleukin-1 receptor antagonist to attenuate inflammatory events in osteoarthritis. Osteoarthritis Cartilage 2007;15(Suppl C):C226-C7
   PubMedGoogle Scholar
• Hirota K, Hasegawa T, Hinata H, et al. Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages. J Control Release 2007;119:69-76
   PubMed Web of Science ®Google Scholar
• Champion JA, Walker A, Mitragotri S. Role of particle size in phagocytosis of polymeric microspheres. Pharm Res 2008;25:1815-21
   PubMed Web of Science ®Google Scholar
• Edwards SH, Cake MA, Spoelstra G, et al. Biodistribution and clearance of intra-articular liposomes in a large animal model using a radiographic marker. J Liposome Res 2007;17:249-61
   PubMed Web of Science ®Google Scholar
• Ramesh DV, Tabara Y, Ikada Y. Biodegradable microspheres for local drug release in the articulus. J Bioactive Compat Polymers 1999;14:137-49
   Web of Science ®Google Scholar
• Nishide M, Kamei S, Takakuea Y, et al. Fate of biodegradable dl-lactic acid oligomer microspheres in the articulus. J Bioactive Compat Polymers 1999;14:385-98
   Web of Science ®Google Scholar
• Liggins RT, Cruz T, Min W, et al. Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits. Inflamm Res 2004;53:363-72
   PubMed Web of Science ®Google Scholar
• Zaffagnini S, Allen AA, Suh JK, et al. Temperature changes in the knee joint during arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc 1996;3:199-201
   PubMedGoogle Scholar
• Hui JH, Chan SW, Li J, et al. Intra-articular delivery of chondroitin sulfate for the treatment of joint defects in rabbit model. J Mol Histol 2007;38:483-9
   PubMed Web of Science ®Google Scholar
• Bozdag S, Calis S, Kas HS, et al. In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium. J Microencapsul 2001;18:443-56
   PubMed Web of Science ®Google Scholar