258
Views
34
CrossRef citations to date
0
Altmetric
Review

Perfluorocarbon compounds as vehicles for pulmonary drug delivery

Pages 247-262 | Published online: 09 May 2007

Bibliography

  • MAIN ML, GRAYBURN PA: Clinical applications of transpulmonary contrast echocardiography. Am. Heart J. (1999) 137(1):144-153.
  • BROWN JJ: Gastrointestinal contrast agents for MR imaging. Magn. Reson. Imaging Clin. N. Am. (1996) 4(1):25-35.
  • MATTREY RF: The potential role of perfluorochemicals (PFCs) in diagnostic imaging. Artif. Cells Blood Substit. Immobil. Biotechnol. (1994) 22:295-313.
  • SPAHN DR, VAN BREMPT R, THEILMEIER G et al.: Perflubron emulsion delays blood transfusions in orthopedic surgery. Anesthesiology (1999)91:1195-1208.
  • SPAHN DR: Current status of artificial oxygen carriers. Adv. Drug Deliv. Rev. (2000) 40(3):143-151.
  • COHN SM: Blood substitutes in surgery. Surgery (2000) 127(6):599-602.
  • LANE TA: Perfluorochemical-based artificial oxygen carrying red cell substitutes. Transfus. Sci. (1995) 16(1):19-31.
  • HABLER O, PAPE A, MEIER J, ZWISSLER B: Artificial oxygen carriers as an alternative to red blood cell transfusion. Anaesthesist (2005) 54(8):741-754.
  • WOLFSON MR, SHAFFER TH: Liquid ventilation: an adjunct for respiratory management. Paediatr. Anaesth. (2004) 14(1):15-23.
  • WOLFSON MR, SHAFFER TH: Pulmonary applications of perfluorochemical liquids: ventilation and beyond. Paediatr. Respir. Rev. (2005) 6:117-127.
  • NUMA AH: Acute lung injury: outcomes and new therapies. Paediatr. Respir. Rev. (2001) 2:22-32.
  • KACMAREK RM: Liquid ventilation. Respir. Care Clin. N. Am. (2002) 8(2):187-209.
  • FUHRMAN BP, HERMAN LJ, ROTTA AT: Partial liquid ventilation: a multifaceted approach to acute respiratory distress syndrome. New Horiz. (1999) 7:433-439.
  • LEHMLER H-J, BUMMER PM, JAY M: Liquid ventilation - a new way to deliver drugs to diseased lungs? Chemtech (1999) 29(10):7-12.
  • KACMAREK RM, WIEDEMANN HP, LAVIN PT et al.: Partial liquid ventilation in adult patients with acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. (2006) 173(8):882-889.
  • COSTANTINO M-L, SHAFFER T, WAUER RR, RUDIGER M: The 5th European symposium on perfluorocarbon (PFC) application. ASAIO J. (2006) 52:483-484.
  • LEHMLER H-J: Synthesis of environmentally relevant fluorinated surfactants-a review. Chemosphere (2005) 58(11):1471-1496.
  • PATEL MM, SZANTO P, YATES B, LONG DM: Survival and histopathologic changes in lungs of hamsters following synthetic liquid breathing. Fed. Proc. (1970) 29:1740-1745.
  • LE BLANC M, RIESS JG, POGGI D, FOLLANA R: Use of lymphoblastoid namalva cell cultures in a toxicity test. Application to the monitoring of detoxification procedures for fluorocarbons to be used as intravascular oxygen carriers. Pharm. Res. (1985) 5:246-248.
  • REICKERT C, PRANIKOFF T, OVERBECK M et al.: The pulmonary and systemic distribution and elimination of perflubron from adult patients treated with partial liquid ventilation. Chest (2001) 119(2):515-522.
  • FLAIM SF: Pharmacokinetics and side effects of perfluorocarbon-based blood substitutes. Artif. Cells Blood Substit. Immobil. Biotechnol. (1994) 22(4):1043-1054.
  • NAKSTAD B, WOLFSON MR, SHAFFER TH et al.: Perfluorochemical liquids modulate cell-mediated inflammatory responses. Crit. Care Med. (2001) 29(9):1731-1737.
  • HIRSCHL RB, OVERBECK MC, PARENT A et al.: Liquid ventilation provides uniform distribution of perfluorocarbons in the setting of respiratory failure. Surgery (1994) 116:159-168.
  • SCOTT RL: The anomalous behavior of fluorocarbon solutions. J. Am. Chem. Soc. (1958) 62:136-145.
  • PATRICK CR: Physicochemical properties of highly fluorinated organic compounds. Chem. Brit. (1971) 7(4):154-156.
  • MUKERJEE P, YANG AYS: Nonideality of mixing of micelles of fluorocarbon and hydrocarbon surfactants and evidence of partial miscibility from differential conductance data. J. Phys. Chem. (1976) 80:1388-1390.
  • KANDLER MA, VON DER HARDT K, SCHOOF E, DOTSCH J, RASCHER W: Persistent improvement of gas exchange and lung mechanics by aerosolized perfluorocarbon. Am. J. Respir. Crit. Care Med. (2001) 164(1):31-35.
  • BUTZ N, PORTE C, COURRIER H, KRAFFT MP, VANDAMME TF: Reverse water-in-fluorocarbon emulsions for use in pressurized metered-dose inhalers containing hydrofluoroalkane propellants. Int. J. Pharm. (2002) 238(1-2):257-269.
  • SCHOOF E, VON DER HARDT K, KANDLER MA et al.: Aerosolized perfluorocarbon reduces adhesion molecule gene expression and neutrophil sequestration in acute respiratory distress. Eur. J. Pharmacol. (2002) 457:195-200.
  • WOLFSON MR, GREENSPAN JS, SHAFFER TH: Pulmonary administration of vasoactive substances by perfluorochemical ventilation. Pediatrics (1996) 97(4):449-455.
  • SHAFFER TH, WOLFSON MR, GREENSPAN JS, RUBENSTEIN SD, STERN RG: Perfluorochemical liquid as a respiratory medium. Artif. Cells Blood Substit. Immobil. Biotechnol. (1994) 22(2):315-326.
  • ZELINKA MA, WOLFSON MR, CALLIGARO I et al.: A comparison of intratracheal and intravenous administration of gentamicin during liquid ventilation. Eur. J. Pediatr. (1997) 156:401-404.
  • CULLEN AB, COX CA, HIPP SJ, WOLFSON MR, SHAFFER TH: Intra-tracheal delivery strategy of gentamicin with partial liquid ventilation. Respir. Med. (1999) 93:770-778.
  • FOX WW, WEIS CM, COX C et al.: Pulmonary administration of gentamicin during liquid ventilation in a newborn lamb lung injury model. Pediatrics (1997) 100(5):e5.
  • DICKSON EW, HEARD SO, TARARA TE et al.: Liquid ventilation with perflubron in the treatment of rats with pneumococcal pneumonia. Crit. Care Med. (2002) 30(2):393-395.
  • SMITH DJ, GAMBONE LM, TARARA T et al.: Liquid dose pulmonary instillation of gentamicin PulmoSpheres® dormulations: Tissue distribution and pharmacokinetics in rabbits. Pharm. Res. (2001) V18(11):1556-1561.
  • FRANZ AR, ROHLKE W, FRANKE RP et al.: Pulmonary administration of perfluorodecaline-gentamicin and perfluorodecaline-vancomycin emulsions. Am. J. Respir. Crit. Care Med. (2001) 164(9):1595-1600.
  • BRUN-BUISSON C, LEMAIRE F: Administration of antibiotics for pneumonia during respiratory failure: reaching the target. Am. J. Respir. Crit. Care Med. (2001) 164(9):1554-1555.
  • DELLAMARY LA, TARARA TE, SMITH DJ et al.: Hollow porous particles in metered dose inhalers. Pharm. Res. (2000) 17(2):168-174.
  • BRUNELLI L, HAMILTON E, DAVIS JM et al.: Perfluorochemical liquids enhance delivery of superoxide dismutase to the lungs of juvenile rabbits. Pediatr. Res. (2006) 60(1):65-70.
  • LANGENBACK EG, DAVIS JM, ROBBINS C et al.: Improved pulmonary distribution of recombinant human Cu/Zn superoxide dismutase, using a modified ultrasonic nebulizer. Pediatr. Pulmonol. (1999) 27(2):124-129.
  • LISBY DA, BALLARD PL, FOX WW et al.: Enhanced distribution of adenovirus-mediated gene transfer to lung parenchyma by perfluorochemical liquid. Hum. Gene Ther. (1997) 8:919-928.
  • WEISS DJ, STRANDJORD TP, JACKSON JC, CLARK JG, LIGGITT D: Perfluorochemical liquid-enhanced adenoviral vector distribution and expression in lungs of spontaneously breathing rodents. Exp. Lung Res. (1999) 25(4):317-333.
  • WEISS DJ, STRANDJORD TP, LIGGITT D, CLARK JG: Perflubron enhances adenovirus-mediated gene expression in lungs of transgenic mice with chronic alveolar filling. Hum. Gene Ther. (1999) 10(14):2287-2293.
  • WEISS DJ, BONNEAU L, ALLEN JM, MILLER AD, HALBERT CL: Perfluorochemical liquid enhances adeno-associated virus-mediated transgene expression in lungs. Mol. Ther. (2000) 2(6):624-630.
  • WEISS DJ, BECKETT T, BONNEAU L et al.: Transient increase in lung epithelial tight junction permeability: an additional mechanism for enhancement of lung transgene expression by perfluorochemical liquids. Mol. Ther. (2003) 8(6):927-935.
  • WEISS DJ, BONNEAU L, LIGGITT D: Use of perfluorochemical liquid allows earlier detection of gene expression and use of less vector in normal lung and enhances gene expression in acutely injured lung. Mol. Ther. (2001) 3(5):734-745.
  • WEISS DJ, BASKIN GB, SHEAN MK, BLANCHARD JL, KOLLS JK: Use of perfluorochemical liquid to enhance adenoviral-mediated gene expression in lungs of spontaneously breathing non-human primates: feasibility and initial studies. Pediatr. Pulmonol. Suppl. (2000) 20:235-236.
  • TREMPER KK, ZACCARI J, CULLEN BF, HUFSTEDLER SM: Liquid-gas partition coefficients of halothane and isoflurane in perfluorodecalin, fluosol-DA, and blood/fluosol-DA mixtures. Anesth. Anal. (1984) 63:690-692.
  • KIMLESS-GARBER DB, WOLFSON MR, CARLSSON C, SHAFFER TH: Halothane administration during liquid ventilation. Respir. Med. (1997) 91:255-262.
  • HSU C-H, JAY M, BUMMER PM, LEHMLER H-J: Chemical stability of esters of nicotinic acid intended for pulmonary administration by liquid ventilation. Pharm. Res. (2003) 20(2003):918-925.
  • SCHUBERT K-V, KALER EW: Microemulsifying fluorinated oils with mixtures of fluorinated and hydrogenated surfactants. Colloids Surf. A (1994) 84:97-106.
  • GURUJEYALAKSHMI G, WANG Y, GIRI SN: Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice. J. Pharmacol. Exp. Ther. (2000) 293(1):82-90.
  • GURUJEYALAKSHMI G, WANG Y, GIRI SN: Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin. Nitric Oxide (2000) 4(4):399-411.
  • VENKATESAN N, CHANDRAKASAN G: In vivo administration of taurine and niacin modulate cyclophosphamide-induced lung injury. Eur. J. Pharmacol. (1994) 292(1):75-80.
  • LEHMLER H-J, FORTIS-SANTIAGO A, NAUDURI D, BUMMER PM: Interaction of long-chain nicotinates with dipalmitoylphosphatidylcholine (DPPC). J. Lipid Res. (2005) 46:535-546.
  • LEHMLER H-J, BUMMER PM: Interaction of a partially fluorinated long-chain nicotinate with dipalmitoylphosphatidylcholine. J. Lipid Res. (2005) 46(11):2415-2422.
  • XU L, VYAS SM, LEHMLER H-J, LUDEWIG G: Structure-activity relationships for cytotoxicity of nicotinic acid ester prodrugs for pulmonary delivery. Abstracts of Papers, 229th ACS National Meeting. San Diego, CA, USA (13-17 March 2005) MEDI-097.
  • WILLIAMS TD, JAY MJ, LEHMLER H-J, STALKER DJ, BUMMER PM: Solubility enhancement of phenol and phenol derivatives in perfluorooctyl bromide. J. Pharm. Sci. (1998) 87:1585-1589.
  • COURRIER HM, VANDAMME TF, KRAFFT MP: Reverse water-in-fluorocarbon emulsions and microemulsions obtained with a fluorinated surfactant. Colloids Surf. A (2004) 244(1-3):141-148.
  • LONOSTRO P, CHOI S-M, KU C-Y, CHEN S-H: Fluorinated microemulsions: a study of the phase behavior and structure. J. Phys. Chem. B (1999) 103(25):5347-5352.
  • MATHIS G, LEEMPOEL P, RAVEY JC, SELVE C, DELPUECH JJ: A novel class of nonionic microemulsions: fluorocarbons in aqueous solutions of fluorinated poly(oxyethylene) surfactants. J. Am. Chem. Soc. (1984) 106(21):6162-6171.
  • CESCHIN C, ROQUES J, MALET-MARTINO MC, LATTES A: Fluorocarbon microemulsions. J. Chem. Tech. Biotechnol. (1985) 35A(2):73-82.
  • SADTLER VM, KRAFFT MP, RIESS JG: Achieving stable, reverse water-in-fluorocarbon emulsions. Angew. Chem. Int. Ed. Engl. (1996) 35(17):1976-1978.
  • SADTLER VM, JEANNEAUX F, KRAFFT MP, RABAL J, RIESS JG: Perfluoroalkylated amphiphiles with a morpholinophosphate or a dimorpholinophosphate polar head group. New. J. Chem. (1998) 22:609-613.
  • RIESS JG, PACE S, ZARIF L: Highly effective surfactants with low hemolytic activity. Adv. Mat. (1991) 3(5):249-251.
  • GUILLOD F, GREINER J, RIESS JG: New anionic glycophospholipids with two perfluorocarbon or two hydrocarbon or mixed hydrophobic chains. Chem. Phys. Lipids (1995) 78:149-162.
  • KRAFFT M-P, ROLLAND J-P, VIERLING P, RIESS JG: New perfluoroalkylated phosphocholines. Effect on particle size and stability of fluorocarbon emulsions. New. J. Chem. (1990) 14(11):869-875.
  • MILIUS A, GREINER J, RIESS JG: Synthesis of F-alkylated glycosides as surfactants for in vivo uses. Effects of the length of the hydrocarbonated spacer in the aglycone on Königs-Knorr reaction, surface activity and biological properties. New J. Chem. (1991) 15:337-344.
  • ZARIF L, GREINER J, PACE S, RIESS JG: Synthesis of perfluoroalkylated xylitol ethers and esters: new surfactants for biomedical uses. J. Med. Chem. (1990) 33(4):1262-1269.
  • KRAFFT MP, VIERLING P, RIESS JG: Synthesis and preliminary data on the biocompatibility and emulsifying properties of perfluoroalkylated phosphoramidates as injectable surfactants. Eur. J. Med. Chem. (1991) 26:545-550.
  • VYAS SM, TURANEK J, KNOETIGOVA P et al.: Synthesis and biocompatibility evaluation of partially fluorinated pyridinium bromides. New J. Chem. (2006) 30(6):944-951.
  • COURRIER HM, KRAFFT MP, BUTZ N et al.: Evaluation of cytotoxicity of new semi-fluorinated amphiphiles derived from dimorpholinophosphate. Biomaterials (2003) 24(4):689-696.
  • COURRIER HM, PONS F, LESSINGER JM et al.: In vivo evaluation of a reverse water-in-fluorocarbon emulsion stabilized with a semifluorinated amphiphile as a drug delivery system through the pulmonary route. Int. J. Pharm. (2004) 282(1-2):131-140.
  • GABRIEL JL, MILLER TF, WOLFSON MR, SHAFFER TH: Quantitative structure-activity relationships of perfluorinated hetero-hydrocarbons as potential respiratory media. Application to oxygen solubility, partition coefficient, viscosity, vapor pressure, and density. ASAIO J. (1996) 42(6):968-973.
  • LEONARD RC: Liquid Ventilation. Anaesth. Intens. Care (1998) 26:11-21.
  • COX CA, WOLFSON MR, SHAFFER TH: Liquid ventilation: a comprehensive overview. Neonatal Net. (1996) 15(3):31-43.
  • SANCHEZ V, MANFREDI A, GREINER J, RIESS JG: (Perfluoroalkyl)- and 1,2-bis(perfluoroalkyl)-iodo- and polybromo ethenes: synthesis and preliminary evaluation as contrast agents for diagnosis. Bull. Soc. Chim Fr. (1994) 131:648-657.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.