In vivo modeling of human liver for pharmacological study using humanized mouse

Bibliography

• Zarnegar R, DeFrances MC, Michalopoulos GK. Hepatocyte growth factor. In: Arias IM, chief editor, The Liver. Raven Press, New York; 1994 . p. 1047-57
   Google Scholar
• Tsanev R. Cell cycle and liver function. In: Reiner J, Holzer H, editors, Results and Problems in Cell Differentiation. Springer-Verlag, Berlin; 1975 . p. 197-248
   Google Scholar
• Stahl WR. Organ weights in primates and other mammals. Science 1965;150:1039-42
   PubMed Web of Science ®Google Scholar
• Thiel V, Gavaler DH, Kam JS, Rapid growth of an intact human liver transplanted into a recipient larger than the donor. Gastroenterology 1987;93:1414-19
   PubMed Web of Science ®Google Scholar
• Heckel JL, Sandgren EP, Dege JL, Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell 1990;62:447-56
   PubMed Web of Science ®Google Scholar
• Mohammed FF, Pennington CJ, Kassiri Z, Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology 2005;41:857-67
   PubMed Web of Science ®Google Scholar
• Sandgren EP, Palmiter RD, Heckel JL, Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell 1991;66:245-56
   PubMed Web of Science ®Google Scholar
• Sandgren EP, Degen JL, Palmiter RD, Replacement of diseased mouse liver by hepatic cell transplantation. Science 1994;263:1149-52
   PubMed Web of Science ®Google Scholar
• Marongju F, Doratiotto S, Montisci S, Liver repopulation and carcinogenesis: two sides of the same coin? Am J Pathol 2008;172:649-857
   Google Scholar
• Rhim JA, Sandgren EP, Palmiter RD, Complete reconstitution of mouse liver with xenogeneic hepatocytes. Proc Natl Acad Sci USA 1995;92:4942-6
   PubMed Web of Science ®Google Scholar
• Michalopoulos GK. Liver regeneration. J Cell Physiol 2007;213:286-300
   PubMed Web of Science ®Google Scholar
• Petersen J, Dandri M, Gupta S, Liver repopulation with xenogeneic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinoma. Proc Natl Acad Sci USA 1998;95:310-5
   PubMed Web of Science ®Google Scholar
• Dandri M, Burda MR, Török E, Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus. Hepatology 2001;33:981-8
   PubMed Web of Science ®Google Scholar
• Mercer DF, Schiller DE, Elliott JF, Hepatitis C virus replication in mice with chimeric human livers. Nat Med 2001;7:927-33
   PubMed Web of Science ®Google Scholar
• Bosma GC, Custer RP, Bosma MJ. A severe combined immunodeficiency mutation in the mouse. Nature 1983;301:527-30
   PubMed Web of Science ®Google Scholar
• Perryman LE. Molecular pathology of severe combined immunodeficiency in mice, horses, and dogs. Vet Pathol 2004;41:95-100
   PubMed Web of Science ®Google Scholar
• Suemizu H, Hasegawa M, Kawai K, Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice. Biochem Biophys Res Commun 2008;377:248-52
   PubMed Web of Science ®Google Scholar
• Kikutani H, Makino S. The murine autoimmune diabetes model: NOD and related strains. Adv Immunol 1992;51:285-322
   PubMed Web of Science ®Google Scholar
• Ohbo K, Suda T, Hashiyama M, Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain. Blood 1996;87:956-67
   PubMed Web of Science ®Google Scholar
• Tateno C, Yoshizane Y, Saito N, Near completely humanized liver in mice shows human-type metabolic responses to drugs. Am J Pathol 2004;165:901-12
   PubMed Web of Science ®Google Scholar
• Meuleman P, Libbrecht L, De Vos R, Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera. Hepatology 2005;41:847-56
   PubMed Web of Science ®Google Scholar
• Kawada N, Kristensen DB, Asahina K, Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J Biol Chem 2001;276:25318-23
   PubMed Web of Science ®Google Scholar
• Nishimura M, Yoshitsugu H, Yokoi T, Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver. Xenobiotica 2005;35:877-90
   PubMed Web of Science ®Google Scholar
• Sarbah SA, Younossi ZM. Hepatitis C: an update on the silent epidemic. J Clin Gastroenterol 2000;30:125-43
   PubMed Web of Science ®Google Scholar
• Meuleman P, Leroux-Roels G. The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV. Antivir Res 2008;80:231-8
   PubMed Web of Science ®Google Scholar
• Tsuge M, Hiraga N, Takaishi H, Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus. Hepatology 2005;42:1046-54
   PubMed Web of Science ®Google Scholar
• Gonzalez FJ, Yu AM. Cytochrome P450 and xenobiotic receptor humanized mice. Ann Rev Pharmacol Toxicol 2006;46:41-64
   PubMed Web of Science ®Google Scholar
• Hewitt NJ, Lecluyse EL, Ferguson SS. Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations. Xenobiotica 2007;37:1196-224
   PubMed Web of Science ®Google Scholar
• Graham MJ, Lake BG. Induction of drug metabolism: species differences and toxicological relevance. Toxicology 2008;254:184-91
   PubMed Web of Science ®Google Scholar
• Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 2004;369:23-37
   PubMed Web of Science ®Google Scholar
• Yu AM, Idle JR, Gonzalez FJ. Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates. Drug Metab Rev 2004;36:243-77
   PubMed Web of Science ®Google Scholar
• Bogaards JJ, Bertrand M, Jackson P, Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man. Xenobiotica 2000;30:1131-52
   PubMed Web of Science ®Google Scholar
• Caldwell J. The current status of attempts to predict species differences in drug metabolism. Drug Metab Rev 1981;12:221-37
   PubMed Web of Science ®Google Scholar
• Masubuchi Y, Iwasa T, Hosokawa S, Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes. J Pharmacol Exp Ther 1997;282:1435-41
   PubMed Web of Science ®Google Scholar
• Katoh M, Sawada T, Soeno Y, In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver. J Pharm Sci 2007;96:428-37
   PubMed Web of Science ®Google Scholar
• Bowen WP, Carey JE, Miah A, Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos 2000;28:781-8
   PubMed Web of Science ®Google Scholar
• Katoh M, Matsui T, Nakajima M, In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver. Drug Metab Dispos 2005;33:754-63
   PubMed Web of Science ®Google Scholar
• Toriyabe T, Nagata K, Takada T, Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics. Mol Pharmacol 2009;75:677-84
   PubMed Web of Science ®Google Scholar
• Jones SA, Moore LB, Shenk JL, The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. Mol Endocrinol 2000;14:27-39
   PubMed Web of Science ®Google Scholar
• Cho IJ, Kim SG. Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation. J Biol Chem 2003;278:44103-12
   PubMed Web of Science ®Google Scholar
• Bjornsson TD, Callaghan JT, Einolf HJ, The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective. Drug Metab Dispos 2003;31:815-32
   PubMed Web of Science ®Google Scholar
• Katoh M, Matsui T, Okumura H, Expression of human phase II enzymes in chimeric mice with humanized liver. Drug Metab Dispos 2005;33:1333-40
   PubMed Web of Science ®Google Scholar
• Xie W, Yeuh M-F, Radominska-Pandya A, Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci USA 2003;100:4150-55
   PubMed Web of Science ®Google Scholar
• Kodama S, Koike C, Negishi M, Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 2004;24:7931-40
   PubMed Web of Science ®Google Scholar
• Zhang J, Huang W, Chua SS, Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR. Science 2002;298:422-4
   PubMed Web of Science ®Google Scholar
• Okumura H, Katoh M, Sawad T, Humanization of excretory pathway in chimeric mice with humanized liver. Toxicol Sci 2007;97:533-8
   PubMed Web of Science ®Google Scholar
• Ko H, Novak E, Peters GR, Pharmacokinetics of single-dose cefmetazole following intramuscular administration of cefmetazole sodium to healthy male volunteers. Antimicrob Agents Chemother 1989;33:508-12
   PubMed Web of Science ®Google Scholar
• Murakawa T, Sakamoto H, Fukada S, Pharmacokinetics of ceftizoxime in animals after parenteral dosing. Antimicrob Agents Chemother 1980;17:157-64
   PubMed Web of Science ®Google Scholar
• Shoda J, Okada K, Inada Y, Bezafibrate induces multidrug-resistance P-Glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice. Hepatol Res 2007;37:548-56
   PubMed Web of Science ®Google Scholar
• Masumoto N, Tateno C, Tachibana A, GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver. J Endocrinol 2007;194:529-37
   PubMed Web of Science ®Google Scholar