1,531
Views
30
CrossRef citations to date
0
Altmetric
Editorial

Predicting and detecting adverse drug reactions in old age: challenges and opportunities

, PhD FRACP FRCP (Professor of Medicine of Old Age)
Pages 527-530 | Published online: 19 Apr 2012

Bibliography

  • Jackson SH, Mangoni AA, Batty GM. Optimization of drug prescribing. Br J Clin Pharmacol 2004;57:231-6
  • Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 2004;57:6-14
  • Trifiro G, Spina E. Age-related changes in pharmacodynamics: focus on drugs acting on central nervous and cardiovascular systems. Curr Drug Metab 2011;12:611-20
  • Corsonello A, Pedone C, Incalzi RA. Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions. Curr Med Chem 2010;17:571-84
  • Routledge PA, O'Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol 2004;57:121-6
  • Pirmohamed M, James S, Meakin S, Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 2004;329:15-19
  • Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med 2011;365:2002-12
  • Rochon PA, Gurwitz JH. Optimising drug treatment for elderly people: the prescribing cascade. BMJ 1997;315:1096-9
  • Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet 2000;356:1255-9
  • Bostock CV, Soiza RL, Mangoni AA. Association between prescribing of antimuscarinic drugs and antimuscarinic adverse effects in older people. Expert Rev Clin Pharmacol 2010;3:441-52
  • Lowry E, Woodman RJ, Soiza RL, Mangoni AA. Associations between the anticholinergic risk scale score and physical function: potential implications for adverse outcomes in older hospitalized patients. J Am Med Dir Assoc 2011;12:565-72
  • Quinn TJ, McArthur K, Ellis G, Stott DJ. Functional assessment in older people. BMJ 2011;343:d4681
  • Brauner DJ, Muir JC, Sachs GA. Treating nondementia illnesses in patients with dementia. JAMA 2000;283:3230-5
  • Mangoni AA. Assessing the adverse effects of antimuscarinic drugs in older patients: which way forward? Expert Rev Clin Pharmacol 2011;4:531-3
  • Jamei M, Dickinson GL, Rostami-Hodjegan A. A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of 'bottom-up' vs 'top-down' recognition of covariates. Drug Metab Pharmacokinet 2009;24:53-75
  • Abramson EL, Barron Y, Quaresimo J, Kaushal R. Electronic prescribing within an electronic health record reduces ambulatory prescribing errors. Jt Comm J Qual Patient Saf 2011;37:470-8
  • Terrell KM, Perkins AJ, Dexter PR, Computerized decision support to reduce potentially inappropriate prescribing to older emergency department patients: a randomized, controlled trial. J Am Geriatr Soc 2009;57:1388-94
  • Classen DC, Phansalkar S, Bates DW. Critical drug-drug interactions for use in electronic health records systems with computerized physician order entry: review of leading approaches. J Patient Saf 2011;7:61-5
  • Smithburger PL, Buckley MS, Bejian S, A critical evaluation of clinical decision support for the detection of drug-drug interactions. Expert Opin Drug Saf 2011;10:871-82
  • Greenwald JL, Halasyamani L, Greene J, Making inpatient medication reconciliation patient centered, clinically relevant and implementable: a consensus statement on key principles and necessary first steps. J Hosp Med 2010;5:477-85
  • Schnipper JL, Hamann C, Ndumele CD, Effect of an electronic medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized trial. Arch Intern Med 2009;169:771-80
  • Boockvar KS, Blum S, Kugler A, Effect of admission medication reconciliation on adverse drug events from admission medication changes. Arch Intern Med 2011;171:860-1
  • Mull HJ, Nebeker JR. Informatics tools for the development of action-oriented triggers for outpatient adverse drug events. AMIA Annu Symp Proc 2008;505-9
  • Rozich JD, Haraden CR, Resar RK. Adverse drug event trigger tool: a practical methodology for measuring medication related harm. Qual Saf Health Care 2003;12:194-200
  • Singh R, McLean-Plunckett EA, Kee R, Experience with a trigger tool for identifying adverse drug events among older adults in ambulatory primary care. Qual Saf Health Care 2009;18:199-204

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.