Psychophysiological stress: a significant parameter in drug pharmacokinetics

Bibliography

• Sheiner LB, Steimer JL. Pharmacokinetic/pharmacodynamic modeling in drug development. Annu Rev Pharmacol Toxicol 2000;40:67-95
   PubMed Web of Science ®Google Scholar
• Waller DG, Renwick AG, Hillier K. Pharmacokinetics. In: Horne T, Kenner H, editors, Medical pharmacology and therapeutics. Elsevier, Saunders, Edinburgh, UK; 2005. p. 17
   Google Scholar
• Gonzalez FJ, Gelboin HV. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab Rev 1994;26:165-83
   PubMed Web of Science ®Google Scholar
• Ingelman-Sundberg M. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future. Trends Pharmacol Sci 2004a;25(4):193-200
   PubMed Web of Science ®Google Scholar
• Ingelman-Sundberg M. Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 2004b;369:89-104
   PubMed Web of Science ®Google Scholar
• Matamoros RA, Levine BS. Stress response and drug metabolism in mice. Fund Appl Toxicol 1996;30(2):255-63
   PubMedGoogle Scholar
• Konstandi M, Johnson EO, Marselos M, et al. Stress-mediated modulation of B(alpha)P-induced hepatic CYP1A1: role of catecholamines. Chem Biol Interact 2004;147:65-77
   PubMed Web of Science ®Google Scholar
• Konstandi M, Marselos M, Radon-Camus AM, et al. The role of stress in the regulation of drug metabolizing enzymes in mice. Eur J Drug Metab Pharmacokinet 1998;23:483-90
   PubMed Web of Science ®Google Scholar
• Konstandi M, Johnson E, Lang MA, et al. Stress modulates the enzymatic inducibility by benzo[alpha]pyrene in the rat liver. Pharmacol Res 2000;42:205-11
   PubMed Web of Science ®Google Scholar
• Daskalopoulos EP, Malliou F, Rentesi G, et al. Stress is a critical player in CYP3A, CYP2C, and CYP2D regulation: role of adrenergic receptor signaling pathways. Am J Physiol Endocrinol Metab 2012;303(1):E40-54
   PubMed Web of Science ®Google Scholar
• Guengerich FP. Cytochrome p450 and chemical toxicology. Chem Res Toxicol 2008;21(1):70-83
   PubMed Web of Science ®Google Scholar
• Nebert DW, Roe AL, Dieter MZ, et al. Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem Pharmacol 2000;59(1):65-85
   PubMed Web of Science ®Google Scholar
• Pelkonen O, Nebert DW. Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis. Pharmacol Rev 1982;34(2):189-222
   PubMed Web of Science ®Google Scholar
• Park GR. Molecular mechanisms of drug metabolism in the critically ill. Br J Anaesth 1996;77:32-49
   PubMed Web of Science ®Google Scholar
• Gonzalez FJ. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat Res 2005;569(1-2):101-10
   PubMed Web of Science ®Google Scholar
• Danielson PB. The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metab 2002;3(6):561-97
   PubMed Web of Science ®Google Scholar
• Sigel R, Sigel A, Sigel H. The ubiquitous roles of cytochrome P450 proteins: metal ions in life sciences. Wiley; New York: 2007. ISBN 0-470-01672-8
   Google Scholar
• Nelson DR. The cytochrome P450 homepage. Hum Genomics 2009;4:59-65
   PubMedGoogle Scholar
• Chen CS, Lin JT, Goss KA, et al. Activation of the anticancer prodrugs cyclophosphamide and ifosfamide: identification of cytochrome P450 2B enzymes and site-specific mutants with improved enzyme kinetics. Mol Pharmacol 2004;65(5):1278-85
   PubMed Web of Science ®Google Scholar
• Available from: http://drnelson.uthsc.edu/human.P450.table.html
   Google Scholar
• Ingelman-Sundberg M. The human genome project and novel aspects of cytochrome P450 research. Toxicol Appl Pharmacol 2005;207:52-6
   PubMedGoogle Scholar
• Ortiz de Montellano PR. Cytochrome P450: structure, mechanism, and biochemistry. Kluwer Academic/Plenum Publishers; New York: 2005
   Google Scholar
• Guengerich FP. Cytochromes P450, drugs, and diseases. Mol Interv 2003;3:194-204
   PubMedGoogle Scholar
• Gonzalez FJ. The molecular biology of cytochrome P450s. Pharmacol Rev 1988;40(4):243-88
   PubMed Web of Science ®Google Scholar
• Wislocki PG, Gadek KM, Chou MW, et al. Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives. Cancer Res 1980;40(10):3661-4
   PubMed Web of Science ®Google Scholar
• Guengerich FP, MacDonald TL. Mechanisms of cytochrome P-450 catalysis. FASEB J 1990;4(8):2453-9
   PubMed Web of Science ®Google Scholar
• Guengerich FP. Molecular advances for the cytochrome P-450 superfamily. Trends Pharmacol Sci 1991;12(8):281-3
   PubMed Web of Science ®Google Scholar
• Hollenberg PF. Mechanisms of cytochrome P450 and peroxidase-catalyzed xenobiotic metabolism. FASEB J 1992;6(2):686-94
   PubMed Web of Science ®Google Scholar
• Rendic S, Guengerich FP. Update information on drug metabolism systems--2009, part II: summary of information on the effects of diseases and environmental factors on human cytochrome P450 (CYP) enzymes and transporters. Curr Drug Metab 2010;11(1):4-84
   PubMed Web of Science ®Google Scholar
• Cheng PY, Morgan ET. Hepatic cytochrome P450 regulation in disease states. Curr Drug Metab 2001;2(2):165-83
   PubMed Web of Science ®Google Scholar
• Johnson EO, Kamilaris TC, Chrousos GP, Gold PW. Mechanisms of stress: a dynamic overview of hormonal and behavioral homeostasis. Neurosci Biobehav Rev 1992;16(2):115-30
   PubMed Web of Science ®Google Scholar
• Chrousos GP, Kino T. Glucocorticoid signaling in the cell. Expanding clinical implications to complex human behavioral and somatic disorders. Ann NY Acad Sci 2009;1179:153-66
   PubMed Web of Science ®Google Scholar
• Chrousos GP, Gold PW. The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. JAMA 1992;267(9):1244-52
   PubMed Web of Science ®Google Scholar
• Dipple A. Formation, metabolism, and mechanism of action of polycyclic aromatic hydrocarbons. Cancer Res 1983;43(5 Suppl):2422s-5s
   PubMed Web of Science ®Google Scholar
• Sugimura T, Sato S. Mutagens-carcinogens in foods. Cancer Res 1983;43(5 Suppl):2415s-21s
   PubMed Web of Science ®Google Scholar
• Guengerich FP. Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species. Chem Biol Interact 1997;106(3):161-82
   PubMed Web of Science ®Google Scholar
• Martignoni M, de Kanter R, Grossi P, et al. An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR. Chem Biol Interact 2004;151:1-11
   PubMed Web of Science ®Google Scholar
• Shimada T, Mimura M, Inoue K, et al. Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. Arch Toxicol 1997;71(6):401-8
   PubMed Web of Science ®Google Scholar
• Choudhary D, Jansson I, Stoilov I, et al. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch Biochem Biophys 2005;436(1):50-61
   PubMed Web of Science ®Google Scholar
• McDonnell WM, Scheiman JM, Traber PG. Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. Gastroenterology 1992;103(5):1509-16
   PubMed Web of Science ®Google Scholar
• Zhang W, Parentau H, Greenly RL, et al. Effect of protein-calorie malnutrition on cytochromes P450 and glutathione S-transferase. Eur J Drug Metab Pharmacokinet 1999;24(2):141-7
   PubMed Web of Science ®Google Scholar
• Kawajiri K. Chapter 15. CYP1A1. Volume 148 IARC Sci Publications, Chichester, UK; 1999. p. 159-72
   Google Scholar
• Cheng PY, Morgan ET. Hepatic cytochrome P450 regulation in disease states. Curr Drug Metab 2001;2(2):165-83
   PubMed Web of Science ®Google Scholar
• Shimada T, Fujii-Kuriyama Y. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. Cancer Sci 2004;95(1):1-6
   PubMed Web of Science ®Google Scholar
• Roymans D, Annaert P, Van Houdt J, et al. Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes. Drug Metab Dispos 2005;33(7):1004-16
   PubMed Web of Science ®Google Scholar
• Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomes. Carcinogenesis 1996;17(11):2429-33
   PubMed Web of Science ®Google Scholar
• Newton DJ, Wang RW, Lu AY; Cytochrome P450 Inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes. Drug Metab Dispos 1995;23(1):154-8
   PubMed Web of Science ®Google Scholar
• Shimada T, Yamazaki H, Foroozesh M, et al. Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1. Chem Res Toxicol 1998;11:1048-56
   PubMed Web of Science ®Google Scholar
• Kobayashi K, Urashima K, Shimada N, Chiba K. Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. Drug Metab Dispos 2003;31:833-6
   PubMed Web of Science ®Google Scholar
• Okey AB. Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 1990;45(2):241-98
   PubMed Web of Science ®Google Scholar
• Haduch A, Wojcikowski J, Daniel WA. Effect of short- and long-term treatment with antidepressant drugs on the activity of rat CYP2A in the liver. Pharmacol Rep 2005;57:774-81
   PubMed Web of Science ®Google Scholar
• Robottom-Ferreira AB, Aquino SR, Queiroga R, et al. Expression of CYP2A3 mRNA and its regulation by 3-methylcholanthrene, pyrazole, and beta-ionone in rat tissues. Braz J Med Biol Res 2003;36:839-44
   PubMed Web of Science ®Google Scholar
• Su T, Ding X. Regulation of the cytochrome P450 2A genes. Toxicol Appl Pharmacol 2004;199:285-94
   PubMed Web of Science ®Google Scholar
• Honkakoski P, Negishi M. The structure, function, and regulation of cytochrome P450 2A enzymes. Drug Metab Rev 1997;29(4):977-96
   PubMed Web of Science ®Google Scholar
• Pelkonen O, Rautio A, Raunio H, Pasanen M. CYP2A6: a human coumarin 7-hydroxylase. Toxicology 2000;144:139-47
   PubMed Web of Science ®Google Scholar
• Konstandi M, Lang MA. Effect of cocaine on hepatic drug metabolism. Eur J Int Med 1996;7:221-6
   Google Scholar
• Martignoni M, Groothuis GM, de Kanter R. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin Drug Metab Toxicol 2006;2(6):875-94
   PubMed Web of Science ®Google Scholar
• Czerwinski M, McLemore TL, Gelboin HV, Gonzalez FJ. Quantification of CYP2B7, CYP4B1, and CYPOR messenger RNAs in normal human lung and lung tumors. Cancer Res 1994;54:1085-91
   PubMed Web of Science ®Google Scholar
• Xie W, Evans RM. Orphan nuclear receptors: the exotics of xenobiotics. J Biol Chem 2001;276:37739-42
   PubMed Web of Science ®Google Scholar
• Lang T, Klein K, Fischer J, et al. Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics 2001;11:399-415
   PubMedGoogle Scholar
• Honkakoski P, Sueyoshi T, Negishi M. Drug-activated nuclear receptors CAR and PXR. Ann Med 2003;35:172-82
   PubMed Web of Science ®Google Scholar
• Martignoni M, Groothuis GM, de Kanter R. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin Drug Metab Toxicol 2006;2(6):875-94
   PubMed Web of Science ®Google Scholar
• Vignati LA, Bogni A, Grossi P, Monshouwer M. A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction. Toxicology 2004;199:23-33
   PubMed Web of Science ®Google Scholar
• Bogaards JJ, Bertrand M, Jackson P, et al. Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man. Xenobiotica 2000;30:1131-52
   PubMed Web of Science ®Google Scholar
• Park SH, Liu X, Hennighausen L, et al. Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption. J Biol Chem 1999;274(11):7421-30
   PubMed Web of Science ®Google Scholar
• Honkakoski P, Kojo A, Lang MA. Regulation of the mouse liver cytochrome P450 2B subfamily by sex hormones and phenobarbital. Biochem J 1992;285(3):979-83
   PubMedGoogle Scholar
• Weaver RJ, Thompson S, Smith G, et al. A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. Biochem Pharmacol 1994;47(5):763-73
   PubMed Web of Science ®Google Scholar
• Zhou SF, Liu JP, Chowbay B. Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 2009;41(2):89-295
   PubMed Web of Science ®Google Scholar
• Dai Y, Rashba-Step J, Cederbaum AI. Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry 1993;32:6928-37
   PubMed Web of Science ®Google Scholar
• Zuber R, Anzenbacherova E, Anzenbacher P. Cytochromes P450 and experimental models of drug metabolism. J Cell Mol Med 2002;6:189-98
   PubMed Web of Science ®Google Scholar
• Niznik HB, Tyndale RF, Sallee FR, et al. The dopamine transporter and cytochrome P45OIID1 (debrisoquine 4-hydroxylase) in brain: resolution and identification of two distinct [3H]GBR-12935 binding proteins. Arch Biochem Biophys 1990;276:424-32
   PubMed Web of Science ®Google Scholar
• Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 2004;369(1):23-37
   PubMed Web of Science ®Google Scholar
• Novak RF, Woodcroft KJ. The alcohol-inducible form of cytochrome P450 (CYP 2E1):role in toxicology and regulation of expression. Arch Pharm Res 2000;23:267-82
   PubMed Web of Science ®Google Scholar
• Salaspuro MP, Lieber CS. Non-uniformity of blood ethanol elimination: its exaggeration after chronic consumption. Ann Clin Res 1978;10:294-7
   PubMedGoogle Scholar
• Wu D, Cederbaum AI. Alcohol, oxidative stress, and free radical damage. Alcohol Res Health 2003;27:277-84
   PubMedGoogle Scholar
• Ohashi Y, Yamada K, Takemoto I, et al. Inhibition of human cytochrome P450 2E1 by halogenated anilines, phenols, and thiophenols. Biol Pharm Bull 2005;28:1221-3
   PubMed Web of Science ®Google Scholar
• Spatzenegger M, Jaeger W. Clinical importance of hepatic cytochrome P450 in drug metabolism. Drug Metab Rev 1995;27(3):397-417
   PubMed Web of Science ®Google Scholar
• Liu YT, Hao HP, Liu CX, et al. Drugs as CYP3A probes, inducers, and inhibitors. Drug Metab Rev 2007;39(4):699-721
   PubMed Web of Science ®Google Scholar
• Pelkonen O, Raunio H. Metabolic activation of toxins: tissue-specific expression and metabolism in target organs. Environ Health Perspect 1997;105(Suppl 4):767-74
   PubMed Web of Science ®Google Scholar
• Shimada T, Guengerich FP. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. Proc Natl Acad Sci USA 1989;86(2):462-5
   PubMed Web of Science ®Google Scholar
• Zhou SF, Xue CC, Yu XQ, et al. Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring. Ther Drug Monit 2007;29(6):687-710
   PubMed Web of Science ®Google Scholar
• Burk O, Wojnowski L. Cytochrome P450 3A and their regulation. Naunyn Schmiedebergs Arch Pharmacol 2004;369(1):105-24
   PubMed Web of Science ®Google Scholar
• Ma J, Graves J, Bradbury JA, et al. Regulation of mouse renal CYP2J5 expression by sex hormones. Mol Pharmacol 2004;65(3):730-43
   PubMed Web of Science ®Google Scholar
• Konstandi M, Cheng J, Gonzalez FJ. Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver. Am J Physiol Endocrinol Metab 2013;304(10):E1118-28
   PubMed Web of Science ®Google Scholar
• Wiwi CA, Waxman DJ. Role of hepatocyte nuclear factors in growth hormone-regulated, sexually dimorphic expression of liver cytochromes P450. Growth Factors 2004;22(2):79-88
   PubMed Web of Science ®Google Scholar
• Waxman DJ, Pampori NA, Ram PA, et al. Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450. Proc Natl Acad Sci USA 1991;88(15):6868-72
   PubMed Web of Science ®Google Scholar
• Pampori NA, Shapiro BH. Gender differences in the responsiveness of the sex-dependent isoforms of hepatic P450 to the feminine plasma growth hormone profile. Endocrinology 1999;140(3):1245-54
   PubMed Web of Science ®Google Scholar
• Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C. Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 2007;116(3):496-526
   PubMed Web of Science ®Google Scholar
• Stranger BE, Forrest MS, Dunning M, et al. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 2007;315:848-53
   PubMed Web of Science ®Google Scholar
• Zhou SF, Liu JP, Lai XS. Substrate specificity, inhibitors and regulation of human cytochrome P450 2D6 and implications in drug development. Curr Med Chem 2009a;16(21):2661-805
   PubMed Web of Science ®Google Scholar
• Zhou SF, Zhou ZW, Yang LP, Cai JP. Substrates, inducers, inhibitors and structure-activity relationships of human cytochrome P450 2C9 and implications in drug development. Curr Med Chem 2009b;16(27):3480-675
   PubMed Web of Science ®Google Scholar
• Nebert DW, Jones JE. Regulation of the mammalian cytochrome P1-450 (CYP1A1) gene. Int J Biochem 1989;21(3):243-52
   PubMedGoogle Scholar
• Ioannides C, Parke DV. The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals. Drug Metab Rev 1990;22(1):1-85
   PubMed Web of Science ®Google Scholar
• Whitlock JP Jr, Okino ST, Dong L, et al. Cytochromes P450 5: induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription. FASEB J 1996;10(8):809-18
   PubMed Web of Science ®Google Scholar
• Pelkonen O, Nebert DW. Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis. Pharmacol Rev 1982;34(2):189-222
   PubMed Web of Science ®Google Scholar
• Vuppugalla R, Shah RB, Chimalakonda AP, et al. Microsomal cytochrome P450 levels and activities of isolated rat livers perfused with albumin. Pharm Res 2003;20(1):81-8
   PubMed Web of Science ®Google Scholar
• Parkinson A, Mudra DR, Johnson C, et al. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. Toxicol Appl Pharmacol 2004;199(3):193-209
   PubMed Web of Science ®Google Scholar
• Kim SK, Novak RF. The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression. Pharmacol Ther 2007;113(1):88-120
   PubMed Web of Science ®Google Scholar
• Kotsovolou O, Ingelman-Sundberg M, Lang MA, et al. Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression. Prog Neuropsychopharmacol Biol Psychiatry 2010;34(6):1075-84
   PubMed Web of Science ®Google Scholar
• Waxman DJ, O'Connor C. Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol 2006;20(11):2613-29
   PubMed Web of Science ®Google Scholar
• Hodgson E, Rose RL. Metabolic interactions of agrochemicals in humans. Pest Manag Sci 2008;64(6):617-21
   PubMed Web of Science ®Google Scholar
• Pelkonen O, Turpeinen M, Hakkola J, et al. Inhibition and induction of human cytochrome P450 enzymes: current status. Arch Toxicol 2008;82(10):667-715
   PubMed Web of Science ®Google Scholar
• Waxman DJ, Holloway MG. Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol 2009;76(2):215-28
   PubMed Web of Science ®Google Scholar
• Chrousos GP. Stress and disorders of the stress system. Nat Rev Endocrinol 2009;5:374-81
   PubMed Web of Science ®Google Scholar
• Levine S, Goldman L, Coover GD. Expectancy and the pituitary-adrenal system. In: Porter R, Knight J, editors, Physiology, emotion and psychosomatic illness. CIBA Foundation Symposium 8. Elsevier/Excerpta Medica; Amsterdam: 1972. p. 281-91
   Google Scholar
• Mason JW. A review of psychoendocrine research on the sympatho-adrenal medullary system. Psychosom Med 1968;30:576-607
   PubMed Web of Science ®Google Scholar
• Selye H. Stress. The physiology and pathophysiology of exposure to stress. Acta; Montreal: 1950
   Google Scholar
• Aguilera G. Corticotropin releasing factor receptors: characterization and actions in the anterior pituitary gland. In: Chrousos GP, Loriaux DL, Gold PW, editors. Mechanisms of physical and emotional stress. Advances in experimental medicine and biology Volume 245 Plenum Press; New York: 1988. p. 83-105
   Google Scholar
• File SE, Clarke A. Exploration motor activity after intraventricular ACTH, morphine and naloxone. Behav Brain Res 1980;2:223-7
   Web of Science ®Google Scholar
• Bernardini R, Kamilaris TC, Calogero AE, et al. Interactions between tumor necrosis factor-a, hypothalamic corticotropin-releasing hormone and adrenocorticotropin secretion in the rat. Endocrinology 1990;126:2876-81
   PubMed Web of Science ®Google Scholar
• Bird SJ, Kuhar MJ. Iontophoretic application of opiates to the locus ceruleus. Brain Res 1977;122:523-33
   PubMed Web of Science ®Google Scholar
• Kvetnansky R, Sabban EL, Palkovits M. Catecholaminergic systems in stress: structural and molecular genetic approaches. Physiol Rev 2009;89:535-606
   PubMed Web of Science ®Google Scholar
• Selye H. A syndrome produced by diverse nocuous agents. Nature 1936;138:32
   Web of Science ®Google Scholar
• Yates E, Marsh D, Maran J. The adrenal cortex. In: Mountcastle V, editor. Medical physiology. 14th edition. CV. Mosby, St. Louis; 1980. p. 1558-601
   Google Scholar
• Krieger D. Cushing's syndrome. Monographs in endocrinology. Volume 22 Springer-Verlag; Berlin: 1982
   Google Scholar
• Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res 2002;53:865-71
   PubMed Web of Science ®Google Scholar
• Blalock JE. A molecular basis for bidirectional communication between the immune and neuroendocrine systems. Physiol Rev 1989;69:1-32
   PubMed Web of Science ®Google Scholar
• Sapolsky R, Krey LC, McEwen BS. The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr Rev 1986;7:284-301
   PubMed Web of Science ®Google Scholar
• Broadhurst PL. Experiments in psychogenetics applications of biomedical genetics to the inheritance of behavior. In: Eysenck HJ, editor. Experiments in personality psychogenetics and psychopharmacology. Volume 1 Routledge and Keegan Paul, London; 1960. p. 1-102
   Google Scholar
• Money J. The syndrome of abuse dwarfism (psychosocial dwarfism or reversible hyposomatotropinism): behavioral data and case report. Am J Dis Child 1977;131:508-13
   PubMedGoogle Scholar
• Money J, Annecillo C, Kelley JF. Abuse-dwarfism syndrome: after rescue, statural and intellectual catchup growth correlate. J Clin Child Psychol 1983;12:279-83
   Google Scholar
• Weigent DA, Blalock JE. Interactions between the neuroendocrine and immune systems: common hormones and receptors. Immunol Rev 1987;100:79-100
   PubMed Web of Science ®Google Scholar
• Antonia K, Anastasia A, Tesseromatis C. Stress can affect drug pharmacokinetics via serum/tissues protein binding and blood flow rate alterations. Eur J Drug Metab Pharmacokinet 2012;37(1):1-7
   PubMed Web of Science ®Google Scholar
• Peng HT, Cheung B. A review of psychophysiological stressors on pharmacokinetics. J Clin Pharmacol 2011;51(11):1499-518
   PubMed Web of Science ®Google Scholar
• Flaten MA, Asli O, Simonsen T. The effect of stress on absorption of acetaminophen. Psychopharmacology (Berl) 2006;185(4):471-8
   PubMed Web of Science ®Google Scholar
• Breslin FC, Hayward M, Baum A. Effect of stress on perceived intoxication and the blood alcohol curve in men and women. Health Psychol 1994;13(6):479-87
   PubMed Web of Science ®Google Scholar
• Jamali F, Kunz-Dober CM. Pain-mediated altered absorption and metabolism of ibuprofen: an explanation for decreased serum enantiomer concentration after dental surgery. Br J Clin Pharmacol 1999;47(4):391-6
   PubMed Web of Science ®Google Scholar
• Gianaros PJ, Quigley KS, Mordkoff JT, Stern RM. Gastric myoelectrical and autonomic cardiac reactivity to laboratory stressors. Psychophysiology 2001;38(4):642-52
   PubMed Web of Science ®Google Scholar
• Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 2004;57(1):6-14
   PubMed Web of Science ®Google Scholar
• Peckett AJ, Wright DC, Riddell MC. The effects of glucocorticoids on adipose tissue lipid metabolism. Metabolism 2011;60(11):1500-10
   PubMed Web of Science ®Google Scholar
• Pervanidou P, Chrousos GP. Metabolic consequences of stress during childhood and adolescence. Metabolism 2012;61(5):611-19
   PubMed Web of Science ®Google Scholar
• Konstandi M, Lang MA, Kostakis D, et al. Predominant role of peripheral catecholamines in the stress-induced modulation of CYP1A2 inducibility by benzo(alpha)pyrene. Basic Clin Pharmacol Toxicol 2008;02:35-44
   Google Scholar
• Konstandi M, Johnson E, Lang MA, et al. Noradrenaline, dopamine, serotonin: different effects of psychological stress on brain biogenic amines in mice and rats. Pharmacol Res 2000;41(3):341-6
   PubMed Web of Science ®Google Scholar
• Konstandi M, Kostakis D, Harkitis P, et al. Benzo(alpha)pyrene-induced up-regulation of CYP1A2 gene expression: role of adrenoceptor-linked signaling pathways. Life Sci 2006;79:331-41
   PubMed Web of Science ®Google Scholar
• Flint MS, Hood BL, Sun M, et al. Proteomic analysis of the murine liver in response to a combined exposure to psychological stress and 7,12-dimethylbenz(a)anthracene. J Proteome Res 2010;9(1):509-20
   PubMed Web of Science ®Google Scholar
• Zordoky BN, El-Kadi AO. Role of NF-kappaB in the regulation of cytochrome P450 enzymes. Curr Drug Metab 2009;10(2):164-78
   PubMed Web of Science ®Google Scholar
• Kennedy JM, Riji AM. Effects of surgery on the pharmacokinetic parameters of drugs. Clin Pharmacokinet 1998;35(4):293-312
   PubMed Web of Science ®Google Scholar
• Chen QM, Alexander D, Sun H, et al. Corticosteroids inhibit cell death induced by doxorubicin in cardiomyocytes: induction of antiapoptosis, antioxidant, and detoxification genes. Mol Pharmacol 2005;67(6):1861-73
   PubMed Web of Science ®Google Scholar
• Lee MY, Clark JE, Williams DE. Induction of flavin-containing monooxygenase (FMO B) in rabbit lung and kidney by sex steroids and glucocorticoids. Arch Biochem Biophys 1993;302(2):332-6
   PubMed Web of Science ®Google Scholar
• Bonamassa B, Ma Y, Liu D. Glucocorticoid receptor-mediated transcriptional regulation of N-acetyltransferase 1 gene through distal promoter. AAPS J 2012;14(3):581-90
   PubMed Web of Science ®Google Scholar
• Sugatani J, Nishitani S, Yamakawa K, et al. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1. Mol Pharmacol 2005;67(3):845-55
   PubMed Web of Science ®Google Scholar
• Bian HS, Ngo SY, Tan W, et al. Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids. Life Sci 2007;81(25-26):1659-67
   PubMed Web of Science ®Google Scholar
• Horsfield BP, Reidy GF, Murray M. Studies on the developmental and adrenal regulation of cytosolic and microsomal epoxide hydrolase activities in rat liver. Biochem Pharmacol 1992;44(4):815-18
   PubMed Web of Science ®Google Scholar
• Ding X, Lichti K, Kim I, et al. Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. J Biol Chem 2006;281(36):26540-51
   PubMed Web of Science ®Google Scholar
• Kolesnichenko LS, KulinskiÄ– VI, Ias'ko MV, et al. Effect of insulin and adrenaline on the activity of enzymes of glutathione metabolism and glutathione concentration in rat organs. Probl Endokrinol (Mosk) 1994;40(3):42-4
   PubMedGoogle Scholar
• Lundqvist G, Morgenstern R. Mechanism of activation of rat liver microsomal glutathione transferase by noradrenaline and xanthine oxidase. Biochem Pharmacol 1992;43(8):1725-8
   PubMed Web of Science ®Google Scholar
• Sies H, Graf P. Hepatic thiol and glutathione efflux under the influence of vasopressin, phenylephrine and adrenaline. Biochem J 1985;226(2):545-9
   PubMed Web of Science ®Google Scholar
• Mikhailova ON, Gulyaeva LF, Filipenko ML. Gene expression of drug metabolizing enzymes in adult and aged mouse liver: a modulation by immobilization stress. Toxicology 2005;210(2-3):189-96
   PubMed Web of Science ®Google Scholar
• Konstandi M, Kostakis D, Harkitis P, et al. Role of adrenoceptor-linked signaling pathways in the regulation of CYP1A1 gene expression. Biochem Pharmacol 2005;69:277-87
   PubMed Web of Science ®Google Scholar
• Jørgensen EH, Celander M, Goksøyr A, Iwata M. The effect of stress on toxicant-dependent cytochrome p450 enzyme responses in the Arctic charr (Salvelinus alpinus). Environ Toxicol Chem 2001;20(11):2523-9
   PubMed Web of Science ®Google Scholar
• Boissy A. Fear and fearfulness in animals. Q Rev Biol 1995;70(2):165-91
   PubMed Web of Science ®Google Scholar
• Curé M, Rolinat JP. Behavioral heterogeneity in Sprague-Dawley rats. Physiol Behav 1992;51(4):771-4
   PubMed Web of Science ®Google Scholar
• Prasad BM, Sorg BA, Ulibarri C, Kalivas PW. Sensitization to stress and psychostimulants. Involvement of dopamine transmission versus the HPA axis. Ann NY Acad Sci 1995;771:617-25
   PubMed Web of Science ®Google Scholar
• Spanagel R, Montkowski A, Allingham K, et al. Anxiety: a potential predictor of vulnerability to the initiation of ethanol self-administration in rats. Psychopharmacology (Berl) 1995;122(4):369-73
   PubMed Web of Science ®Google Scholar
• Flint M, McCarty K, Jenkins F, et al. Psychological stress accelerates the onset of tumour formation and alters the type and location of tumours in a DMBA mouse carcinogenesis model. Stress Health 2010;27(3):129-38
   Google Scholar
• Konstandi M, Kostakis D, Johnson E, et al. Evidence of alpha2-adrenoceptor involvement in B[alpha]P induction processes of drug-metabolizing enzymes: the effect of stress. Eur J Drug Metab Pharmacokinet 1998;23:491-5
   PubMed Web of Science ®Google Scholar
• Niwa T, Tsutsui M, Kishimoto K, et al. Inhibition of drug-metabolizing enzyme activity in human hepatic cytochrome P450s by bisphenol A. Biol Pharm Bull 2000;23(4):498-501
   PubMed Web of Science ®Google Scholar
• Arinç E, Arslan S, Adali O. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver. Arch Toxicol 2005;79(8):427-33
   PubMed Web of Science ®Google Scholar
• Rentesi G, Antoniou K, Marselos M, et al. Early maternal deprivation-induced modifications in the neurobiological, neurochemical and behavioural profile of adult rats. Behav Brain Res 2013;244:29-37
   PubMed Web of Science ®Google Scholar
• Hay N. Interplay between FOXO, TOR, and Akt. Biochim Biophys Acta 2011;1813(11):1965-70
   PubMed Web of Science ®Google Scholar