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Expert Opinion on Drug Metabolism & Toxicology Volume 12, 2016 - Issue 1
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Reviews

Iron-based phosphate binders – a new element in management of hyperphosphatemia

Amy Barton PaiDepartment of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY12208, USACorrespondence[email protected]
,
Soo Min JangDepartment of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY12208, USA
&
Nicole WegrzynDepartment of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY12208, USA
Pages 115-127 | Published online: 16 Nov 2015

Bibliography

  • Papers of special note have been highlighted as either of interest (*) or of considerable interest (**) to readers.
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* Key study identifying serum phosphorus as a strong risk factor for mortality.

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** Phase III safety and efficacy trial for ferric citrate.

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** Phase III safety and efficacy trial for sucroferric oxyhydroxide.

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* Detailed experiments of sucroferric oxyhydroxide binding in vitro.

  • Product Information: VELPHORO(R) oral chewable tablets, sucroferric oxyhydroxide oral chewable tablets. Waltham, MA: Fresenius Medical Care North America (per manufactuer); 2013.
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* Study of animal model of vascular calcification with ferric citrate.

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* Extensive review of clinical challenges in iron administration in kidney disease.

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* Provides statistical analyses of secondary endpoints including aluminum concentrations.

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