180
Views
10
CrossRef citations to date
0
Altmetric
Reviews

Current advanced bioluminescence technology in drug discovery

, PhD
Pages 373-389 | Published online: 03 Apr 2009

Bibliography

  • de Wet JR, Wood KV, Helinski DR, DeLuca M. Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc Natl Acad Sci USA 1985;82(23):7870-3
  • Nguyen VT, Morange M, Bensaude O. Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells. Anal Biochem 1988;171(2):404-8
  • Naylor LH. Reporter gene technology: the future looks bright. Biochem Pharmacol 1999;58(5):749-57
  • Wood KV, Lam YA, Seliger HH, McElroy WD. Complementary DNA coding click beetle luciferases can elicit bioluminescence of different colors. Science 1989;244(4905):700-2
  • Viviani VR, Silva AC, Perez GL, et al. Cloning and molecular characterization of the cDNA for the Brazilian larval click-beetle Pyrearinus termitilluminans luciferase. Photochem Photobiol 1999;70(2):254-60
  • Viviani VR, Bechara EJ, Ohmiya Y. Cloning, sequence analysis, and expression of active Phrixothrix railroad-worms luciferases: relationship between bioluminescence spectra and primary structures. Biochemistry 1999;38(26):8271-9
  • Lorenz WW, McCann RO, Longiaru M, Cormier MJ. Isolation and expression of a cDNA encoding Renilla reniformis luciferase. Proc Natl Acad Sci USA 1991;88(10):4438-42
  • Nakajima Y, Kobayashi K, Yamagishi K, et al. cDNA cloning and characterization of a secreted luciferase from the luminous Japanese ostracod, Cypridina noctiluca. Biosci Biotechnol Biochem 2004;68(3):565-70
  • Thompson EM, Nagata S, Tsuji FI. Cloning and expression of cDNA for the luciferase from the marine ostracod Vargula hilgendorfii. Proc Natl Acad Sci USA 1989;86(17):6567-71
  • Masuda T, Tatsumi H, Nakano E. Cloning and sequence analysis of cDNA for luciferase of a Japanese firefly, Luciola cruciata. Gene 1989;77(2):265-70
  • Fujino T, Yamamoto T. Cloning and functional expression of a novel long-chain acyl-CoA synthetase expressed in brain. J Biochem 1992;111(2):197-203
  • Ohmiya Y, Ohba N, Toh H, Tsuji F. Cloning, expression and sequence analysis of cDNA for the luciferases from the Japanese fireflies, Pyrocoelia miyako and Hotaria parvula. Photochem Photobiol 1995;62(2):309-13
  • Gomi K, Hirokawa K, Kajiyama N. Molecular cloning and expression of the cDNAs encoding luciferin-regenerating enzyme from Luciola cruciata and Luciola lateralis. Gene 2002;294(1-2):157-66
  • Choi YS, Lee KS, Bae JS, et al. Molecular cloning and expression of a cDNA encoding the luciferase from the firefly, Hotaria unmunsana. Comp Biochem Physiol B Biochem Mol Biol 2002;132(3):661-70
  • Lee KS, Park HJ, Bae JS, et al. Molecular cloning and expression of a cDNA encoding the luciferase from the firefly, Pyrocoelia rufa. J Biotechnol 2001;92(1):9-19
  • Branchini BR, Southworth TL, DeAngelis JP, et al. Luciferase from the Italian firefly Luciola italica: molecular cloning and expression. Comp Biochem Physiol B Biochem Mol Biol 2006;145(2):159-67
  • Emamzadeh AR, Hosseinkhani S, Sadeghizadeh M, et al. cDNA cloning, expression and homology modeling of a luciferase from the firefly Lampyroidea maculata. J Biochem Mol Biol 2006;39(5):578-85
  • Alipour BS, Hosseinkhani S, Nikkhah M, et al. Molecular cloning, sequence analysis, and expression of a cDNA encoding the luciferase from the glow-worm, Lampyris turkestanicus. Biochem Biophys Res Commun 2004;325(1):215-22
  • Stolz U, Velez S, Wood KV, et al. Darwinian natural selection for orange bioluminescent color in a Jamaican click beetle. Proc Natl Acad Sci USA 2003;100(25):14955-9
  • Markova SV, Golz S, Frank LA, et al. Cloning and expression of cDNA for a luciferase from the marine copepod Metridia longa. A novel secreted bioluminescent reporter enzyme. J Biol Chem 2004;279(5):3212-7
  • Viviani V, Uchida A, Suenaga N, et al. Thr226 is a key residue for bioluminescence spectra determination in beetle luciferases. Biochem Biophys Res Commun 2001;280(5):1286-91
  • Ohmiya Y, Sumiya M, Viviani VR, Ohba N. Comparative aspects of a luciferase molecule from the Japanese luminous beetle, Rhagophthalmus ohbai. Sci Rept Yokosuka City Mus 2000;47:31-8
  • Shimomura O. Bioluminescence. First edition. Singapore: World Scientific Publishing Co. Pte. Ltd., 2006
  • Seliger HH, Mc EW. Spectral emission and quantum yield of firefly bioluminescence. Arch Biochem Biophys 1960;88:136-41
  • Koo JA, Schmidt SP, Schuster GB. Bioluminescence of the firefly: key steps in the formation of the electronically excited state for model systems. Proc Natl Acad Sci USA 1978;75(1):30-3
  • Beutler E, Baluda MC. Simplified determination of blood adenosine triphosphate Using the firefly system. Blood 1964;23:688-98
  • Hattori N, Sakakibara T, Kajiyama N, et al. Enhanced microbial biomass assay using mutant luciferase resistant to benzalkonium chloride. Anal Biochem 2003;319(2):287-95
  • Mitsuda N, Roses AD, Vitek MP. Transcriptional regulation of the mouse presenilin-1 gene. J Biol Chem 1997;272(38):23489-97
  • Nakajima Y, Ikeda M, Kimura T, et al. Bidirectional role of orphan nuclear receptor RORalpha in clock gene transcriptions demonstrated by a novel reporter assay system. FEBS Lett 2004;565(1-3):122-6
  • Nakajima Y, Kimura T, Sugata K, et al. Multicolor luciferase assay system: one-step monitoring of multiple gene expressions with a single substrate. Biotechniques 2005;38(6):891-4
  • Izumo M, Johnson CH, Yamazaki S. Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping. Proc Natl Acad Sci USA 2003;100(26):16089-94
  • Vitaterna MH, Ko CH, Chang AM, et al. The mouse clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude. Proc Natl Acad Sci USA 2006;103(24):9327-32
  • Zhao WN, Malinin N, Yang FC, et al. CIPC is a mammalian circadian clock protein without invertebrate homologues. Nat Cell Biol 2007;9(3):268-75
  • Noguchi T, Ikeda M, Ohmiya Y, Nakajima Y. Simultaneous monitoring of independent gene expression patterns in two types of cocultured fibroblasts with different color-emitting luciferases. BMC Biotechnol 2008;8:40
  • Verhaegent M, Christopoulos TK. Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization. Anal Chem 2002;74(17):4378-85
  • Badr CE, Hewett JW, Breakefield XO, Tannous BA. A highly sensitive assay for monitoring the secretory pathway and ER stress. PLoS ONE 2007;2(6):e571
  • Suzuki T, Usuda S, Ichinose H, Inouye S. Real-time bioluminescence imaging of a protein secretory pathway in living mammalian cells using Gaussia luciferase. FEBS Lett 2007;581(24):4551-6
  • Ketteler R, Seed B. Quantitation of autophagy by luciferase release assay. Autophagy 2008;4(6):801-6
  • Hewett JW, Tannous B, Niland BP, et al. Mutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells. Proc Natl Acad Sci USA 2007;104(17):7271-6
  • Yamagishi K, Enomoto T, Ohmiya Y. Perfusion-culture-based secreted bioluminescence reporter assay in living cells. Anal Biochem 2006;354(1):15-21
  • Shimomura O, Goto T, Hirata Y. Crystalline Cypridina luciferin. Bull Chem Soc Jpn 1957;30:929-33
  • Kishi Y, Goto T, Inoue S, et al. Cypridina bioluminescence III Total synthesis of Cypridina luciferin. Tetrahedron Lett 1966;29:3445-50
  • Wu C, Kawasaki K, Ohgiya S, Ohmiya Y. Syntheses and evaluation of the bioluminescent activity of (S)-Cypridina luciferin and its analogs. Tetrahedron Lett 2006;47(5):753-6
  • Wu C, Suzuki-ogoh C, Ohmiya Y. Dual-reporter assay using two secreted luciferase genes. Biotechniques 2007;42(3):290-2
  • Nishide SY, Honma S, Nakajima Y, et al. New reporter system for Per1 and Bmal1 expressions revealed self-sustained circadian rhythms in peripheral tissues. Genes Cells 2006;11(10):1173-82
  • Michelini E, Cevenini L, Mezzanotte L, et al. Combining intracellular and secreted bioluminescent reporter proteins for multicolor cell-based assays. Photochem Photobiol Sci 2008;7(2):212-7
  • Michelini E, Cevenini L, Mezzanotte L, et al. Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening. Anal Chem 2008;80(1):260-7
  • Pfleger KD, Eidne KA. Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat Methods 2006;3(3):165-74
  • Wu P, Brand L. Resonance energy transfer: methods and applications. Anal Biochem 1994;218(1):1-13
  • Dacres H, Dumancic MM, Horne I, Trowell SC. Direct comparison of fluorescence- and bioluminescence-based resonance energy transfer methods for real-time monitoring of thrombin-catalysed proteolytic cleavage. Biosens Bioelectron 2009;24(5):1164-70
  • Loening AM, Fenn TD, Gambhir SS. Crystal structures of the luciferase and green fluorescent protein from Renilla reniformis. J Mol Biol 2007;374(4):1017-28
  • Hoshino H, Nakajima Y, Ohmiya Y. Luciferase-YFP fusion tag with enhanced emission for single-cell luminescence imaging. Nat Methods 2007;4(8):637-9
  • Ward WW, Cormier MJ. Protein-protein interaction as measured by biolumonescence energy transfer in Renilla. Methods Enzymol 1978;57:257-67
  • Ward WW, Cormier MJ. An energy transfer protein in coelenterate bioluminescence. Characterization of the Renilla green-fluorescent protein. J Biol Chem 1979;254(3):781-8
  • Loening AM, Fenn TD, Wu AM, Gambhir SS. Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output. Protein Eng Des Sel 2006;19(9):391-400
  • Loening AM, Wu AM, Gambhir SS. Red-shifted Renilla reniformis luciferase variants for imaging in living subjects. Nat Methods 2007;4(8):641-3
  • Xu X, Soutto M, Xie Q, et al. Imaging protein interactions with bioluminescence resonance energy transfer (BRET) in plant and mammalian cells and tissues. Proc Natl Acad Sci USA 2007;104(24):10264-9
  • Pfleger KD, Dromey JR, Dalrymple MB, et al. Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells. Cell Signal 2006;18(10):1664-70
  • Kocan M, See HB, Seeber RM, et al. Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein-coupled receptors in live cells. J Biomol Screen 2008;13(9):888-98
  • Ozawa T, Kaihara A, Sato M, et al. Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing. Anal Chem 2001;73(11):2516-21
  • Paulmurugan R, Umezawa Y, Gambhir SS. Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies. Proc Natl Acad Sci USA 2002;99(24):15608-13
  • Kim SB, Otani Y, Umezawa Y, Tao H. Bioluminescent indicator for determining protein-protein interactions using intramolecular complementation of split click beetle luciferase. Anal Chem 2007;79(13):4820-6
  • Paulmurugan R, Gambhir SS. Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragment-assisted complementation. Anal Chem 2003;75(7):1584-9
  • Remy I, Michnick SW. A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nat Methods 2006;3(12):977-9
  • Hu CD, Chinenov Y, Kerppola TK. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell 2002;9(4):789-98
  • Hu CD, Kerppola TK. Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis. Nat Biotechnol 2003;21(5):539-45
  • Rebois RV, Robitaille M, Petrin D, et al. Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells. Methods 2008;45:214-8
  • Rebois RV, Robitaille M, Gales C, et al. Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. J Cell Sci 2006;119(Pt 13):2807-18
  • Heroux M, Hogue M, Lemieux S, Bouvier M. Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. J Biol Chem 2007;282(43):31610-20
  • Harikumar KG, Happs RM, Miller LJ. Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor. Biochim Biophys Acta 2008;1778(11):2555-63
  • Gandia J, Galino J, Amaral OB, et al. Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique. FEBS Lett 2008;582(20):2979-84
  • Carriba P, Navarro G, Ciruela F, et al. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nat Methods 2008;5(8):727-33
  • Kroeger KM, Hanyaloglu AC, Seeber RM, et al. Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer. J Biol Chem 2001;276(16):12736-43
  • Hanyaloglu AC, Seeber RM, Kohout TA, et al. Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2. J Biol Chem 2002;277(52):50422-30
  • Gales C, Rebois RV, Hogue M, et al. Real-time monitoring of receptor and G-protein interactions in living cells. Nat Methods 2005;2(3):177-84
  • Angers S, Salahpour A, Joly E, et al. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA 2000;97(7):3684-9
  • Pfleger KD, Dalrymple MB, Dromey JR, Eidne KA. Monitoring interactions between G-protein-coupled receptors and beta-arrestins. Biochem Soc Trans 2007;35(Pt 4):764-6
  • Perroy J, Pontier S, Charest PG, et al. Real-time monitoring of ubiquitination in living cells by BRET. Nat Methods 2004;1(3):203-8
  • Shenoy SK, Lefkowitz RJ. Resonating to the music of ubiquitination. Nat Methods 2004;1(3):191-3
  • Michelini E, Mirasoli M, Karp M, et al. Development of a bioluminescence resonance energy-transfer assay for estrogen-like compound in vivo monitoring. Anal Chem 2004;76(23):7069-76
  • Paulmurugan R, Gambhir SS. Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals. Cancer Res 2005;65(16):7413-20
  • Paulmurugan R, Massoud TF, Huang J, Gambhir SS. Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Res 2004;64(6):2113-9
  • Paulmurugan R, Gambhir SS. Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions. Anal Chem 2007;79(6):2346-53
  • Paulmurugan R, Gambhir SS. An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proc Natl Acad Sci USA 2006;103(43):15883-8
  • Endoh T, Mie M, Funabashi H, et al. Construction of intramolecular luciferase complementation probe for detecting specific RNA. Bioconjug Chem 2007;18(3):956-62
  • Kim SB, Ozawa T, Watanabe S, Umezawa Y. High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of split Renilla luciferase. Proc Natl Acad Sci USA 2004;101(32):11542-7
  • Kim SB, Ozawa T, Umezawa Y. A genetically encoded indicator for assaying bioactive chemicals that induce nuclear transport of glucocorticoid receptor. Anal Biochem 2005;347(2):213-20
  • Kim SB, Takao R, Ozawa T, Umezawa Y. Quantitative determination of protein nuclear transport induced by phosphorylation or by proteolysis. Anal Chem 2005;77(21):6928-34
  • Kanno A, Ozawa T, Umezawa Y. Genetically encoded optical probe for detecting release of proteins from mitochondria toward cytosol in living cells and mammals. Anal Chem 2006;78(23):8076-81
  • Ando Y, Niwa K, Yamada N, et al. Firefly bioluminescence quantum yield and colour change by pH-sensitive green emission. Nat Photonics 2008;2(1):44-7
  • Welsh DK, Yoo SH, Liu AC, et al. Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol 2004;14(24):2289-95
  • Ward WW, Cormier MJ. Energy transfer via protein-protein interaction in Renilla bioluminescence. Photochem Photobiol 1978;27:389-96
  • Miyawaki A. Bringing bioluminescence into the picture. Nat Methods 2007;4(8):616-7
  • Nakajima Y, Kimura T, Suzuki C, Ohmiya Y. Improved expression of novel red- and green-emitting luciferases of Phrixothrix railroad worms in mammalian cells. Biosci Biotechnol Biochem 2004;68(4):948-51
  • Xing Y, So MK, Koh AL, et al. Improved QD-BRET conjugates for detection and imaging. Biochem Biophys Res Commun 2008;372(3):388-94
  • So MK, Loening AM, Gambhir SS, Rao J. Creating self-illuminating quantum dot conjugates. Nat Protoc 2006;1(3):1160-4
  • So MK, Xu C, Loening AM, et al. Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol 2006;24(3):339-43

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.