2-Iminobiotin for the treatment of perinatal asphyxia

Bibliography

• Papadopoulos MD, Anday E. Biochemical basis of hypoxic-ischemic encephalopathy. In: Buonocore G, Bracci R, Weindling M, editors. Neonatology: a practical approach to neonatal diseases. © Springer-Verlag Italia, Italy 2011
   Google Scholar
• Biban P, Silvagni D. Early detection of neonatal depression and asphyxia. In: Buonocore G, Bracci R, Weindling M, editors. Neonatology: a practical approach to neonatal diseases. © Springer-Verlag Italia; 2011
   Google Scholar
• Platt MJ, Cans C, Johnson A, et al. Trends in cerebral palsy among infants of very low birthweight (< 1500 g) or born prematurely (< 32 weeks) in 16 European centres: a database study. Lancet 2007;369(9555):43-50
   PubMed Web of Science ®Google Scholar
• Allin M, Walshe M, Fern A, et al. Cognitive maturation in preterm and term born adolescents. J Neurol Neurosurg Psychiatry 2008;79(4):381-6
   PubMed Web of Science ®Google Scholar
• Larroque B, Ancel PY, Marret S, et al. Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study. Lancet 2008;371(9615):813-20
   PubMed Web of Science ®Google Scholar
• Azzopardi DV, Strohm B, Edwards AD, et al. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med 2009;361(14):1349-58
   PubMed Web of Science ®Google Scholar
• Gluckman PD, Hanson MA, Pinal C. The developmental origins of adult disease. Matern Child Nutr 2005;1(3):130-41
   PubMed Web of Science ®Google Scholar
• Himmelmann K, Hagberg G, Beckung E, et al. The changing panorama of cerebral palsy in Sweden. IX. Prevalence and origin in the birth-year period 1995-1998. Acta Paediatr 2005;94(3):287-94
   PubMed Web of Science ®Google Scholar
• Hossmann KA. Experimental models for the investigation of brain ischemia. Cardiovasc Res 1998;39(1):106-20
   PubMed Web of Science ®Google Scholar
• Perrone S, Stazzoni G, Tataranno ML, Buonocore G. New pharmacologic and therapeutic approaches for hypoxic-ischemic encephalopathy in the newborn. J Matern Fetal Neonatal Med 2012;25(Suppl 1):83-8
   PubMed Web of Science ®Google Scholar
• Buonocore G, Perrone S, Turrisi G, et al. New pharmacological approaches in infants with hypoxic-ischemic encephalopathy. Curr Pharm Des 2012;18(21):3086-100
   PubMed Web of Science ®Google Scholar
• Reith J, Jørgensen HS, Pedersen PM, et al. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet 1996;347(8999):422-5
   PubMed Web of Science ®Google Scholar
• Cilio MR, Ferriero DM. Synergistic neuroprotective therapies with hypothermia. Semin Fetal Neonatal Med 2010;15(5):293-8
   PubMed Web of Science ®Google Scholar
• Hobbs C, Thoresen M, Tucker A, et al. Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia. Stroke 2008;39(4):1307-13
   PubMed Web of Science ®Google Scholar
• Nita DA, Nita V, Spulber S, et al. Oxidative damage following cerebral ischemia depends on reperfusion - a biochemical study in rat. J Cell Mol Med 2001;5(2):163-70
   PubMed Web of Science ®Google Scholar
• Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 2001;21(1):2-14
   PubMed Web of Science ®Google Scholar
• Budd SL. Mechanisms of neuronal damage in brain hypoxia/ischemia: focus on the role of mitochondrial calcium accumulation. Pharmacol Ther 1998;80(2):203-29
   PubMed Web of Science ®Google Scholar
• Mori T, Tateishi N, Kagamiishi Y, et al. Attenuation of a delayed increase in the extracellular glutamate level in the peri-infarct area following focal cerebral ischemia by a novel agent ONO-2506. Neurochem Int 2004;45(2-3):381-7
   PubMed Web of Science ®Google Scholar
• Kortenbruck G, Berger E, Speckmann EJ, et al. RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients. Neurobiol Dis 2001;8(3):459-68
   PubMed Web of Science ®Google Scholar
• Hollmann M, Heinemann S. Cloned glutamate receptors. Annu Rev Neurosci 1994;17:31-108
   PubMed Web of Science ®Google Scholar
• Kondo M, Sumino R, Okado H. Combinations of AMPA receptor subunit expression in individual cortical neurons correlate with expression of specific calcium-binding proteins. J Neurosci 1997;17(5):1570-81
   PubMed Web of Science ®Google Scholar
• Kilb W. Development of the GABAergic system from birth to adolescence. Neuroscientist 2012;18(6):613-30
   PubMed Web of Science ®Google Scholar
• Takayama C, Inoue Y. Morphological development and maturation of the GABAergic synapses in the mouse cerebellar granular layer. Brain Res Dev Brain Res 2004;150(2):177-90
   PubMedGoogle Scholar
• Nowak L, Bregestovski P, Ascher P, et al. Magnesium gates glutamate-activated channels in mouse central neurones. Nature 1984;307(5950):462-5
   PubMed Web of Science ®Google Scholar
• Mishina M, Sakimura K, Mori H, et al. A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels. Biochem Biophys Res Commun 1991;180(2):813-21
   PubMed Web of Science ®Google Scholar
• Boucher JL, Moali C, Tenu JP. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. Cell Mol Life Sci 1999;55:1015e28
   Web of Science ®Google Scholar
• Sutton HC, Winterbourn CC. On the participation of higher oxidation states of iron and copper in Fenton reactions. Free Radic Biol Med 1989;6:53e60
   Web of Science ®Google Scholar
• Turrens JF. Superoxide production by the mitochondrial respiratory chain. Biosci Rep 1997;17:3-8
   PubMed Web of Science ®Google Scholar
• Kowaltowski AJ, Vercesi AE. Mitochondrial damage induced by conditions of oxidative stress. Free Radic Biol Med 1999;26:463e71
   Web of Science ®Google Scholar
• Liberatori S, Canas B, Tani C, et al. Proteomic approach to the identification of voltage-dependent anion channel protein isoforms in guinea pig brain synaptosomes. Proteomics 2004;4:1335e40
   Web of Science ®Google Scholar
• Beal MF, Palomo T, Kostrzewa RM, Archer T. Neuroprotective and neurorestorative strategies for neuronal injury. Neurotox Res 2000;2(2-3):71-84
   PubMed Web of Science ®Google Scholar
• Chen H, Chan DC. Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases. Hum Mol Genet 2009;18(R2):R169-76
   PubMed Web of Science ®Google Scholar
• Ginet V, Puyal J, Clarke PG, Truttmann AC. Enhancement of autophagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms. Am J Pathol 2009;175(5):1962-74
   PubMed Web of Science ®Google Scholar
• Goldman SJ, Taylor R, Zhang Y, Jin S. Autophagy and the degradation of mitochondria. Mitochondrion 2010;10(4):309-15
   PubMed Web of Science ®Google Scholar
• Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005;2:1509-18
   Web of Science ®Google Scholar
• Wong E, Cuervo AM. Integration of clearance mechanisms: the proteasome and autophagy. Cold Spring Harb Perspect Biol 2010;2(12):a006734
   PubMed Web of Science ®Google Scholar
• Cheng L, Wang SH, Jia N, et al. Environmental stimulation influence the cognition of developing mice by inducing changes in oxidative and apoptosis status. Brain Dev 2012(12):S0387-7604; 00304-X
   Google Scholar
• Sies H. Damage to plasmid DNA by singlet oxygen and its protection. Mutat Res 1993;299(3-4):183-91
   PubMed Web of Science ®Google Scholar
• Namura S, Nagata I, Takami S, et al. Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 2001;32(8):1906-11
   PubMed Web of Science ®Google Scholar
• Charriaut-Marlangue C, Pollard H, Ben-Ari Y. Is ischemic cell death of the apoptotic type? Adv Neurol 1996;71:425-30
   PubMedGoogle Scholar
• Guégan C, Ceballos-Picot I, Nicole A, et al. Recruitment of several neuroprotective pathways after permanent focal ischemia in mice. Exp Neurol 1998;154(2):371-80
   PubMed Web of Science ®Google Scholar
• Wen J, Watanabe K, Ma M, et al. Edaravone inhibits JNK-c-Jun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats. Biol Pharm Bull 2006;29(4):713-18
   PubMed Web of Science ®Google Scholar
• Mishra OP, Akhter W, Ashraf QM, Delivoria-Papadopoulos M. Hypoxia-induced modification of poly (ADP-ribose) polymerase and dna polymerase beta activity in cerebral cortical nuclei of newborn piglets: role of nitric oxide. Neuroscience 2003;119(4):1023-32
   PubMed Web of Science ®Google Scholar
• Amé JC, Spenlehauer C, de Murcia G. The PARP superfamily. Bioessays 2004;26(8):882-93
   PubMed Web of Science ®Google Scholar
• Hong SJ, Dawson TM, Dawson VL. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol Sci 2004;25(5):259-64
   PubMed Web of Science ®Google Scholar
• Plesnila N, Zhu C, Culmsee C, et al. Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J Cereb Blood Flow Metab 2004;24(4):458-66
   PubMed Web of Science ®Google Scholar
• Cipriani G, Rapizzi E, Vannacci A, et al. Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction. J Biol Chem 2005;280(17):17227-34
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhang X, Park TS, Gidday JM. Cerebral endothelial cell apoptosis after ischemia-reperfusion: role of PARP activation and AIF translocation. J Cereb Blood Flow Metab 2005;25(7):868-77
   PubMed Web of Science ®Google Scholar
• Ermak G, Davies KJ. Calcium and oxidative stress: from cell signaling to cell death. Mol Immunol 2002;38(10):713-21
   PubMed Web of Science ®Google Scholar
• Rousset CI, Baburamani AA, Thornton C, Hagberg H. Mitochondria and perinatal brain injury. J Matern Fetal Neonatal Med 2012;25 Suppl 1:35-8
   PubMed Web of Science ®Google Scholar
• Shi Y. Caspase activation, inhibition, and reactivation: a mechanistic view. Protein Sci 2004;13(8):1979-87
   PubMed Web of Science ®Google Scholar
• Qi JP, Wu AP, Wang DS, et al. Correlation between neuronal injury and Caspase-3 after focal ischemia in human hippocampus. Chin Med J (Engl) 2004;117(10):1507-12
   PubMed Web of Science ®Google Scholar
• Hagberg H, Mallard C, Rousset CI, Xiaoyang W. Apoptotic mechanisms in the immature brain: involvement of mitochondria. J Child Neurol 2009;24:1141-6
   PubMed Web of Science ®Google Scholar
• Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Curr Med Chem 2007;14:1189-97
   PubMed Web of Science ®Google Scholar
• Hailer NP. Immunosuppression after traumatic or ischemic CNS damage: it is neuroprotective and illuminates the role of microglial cells. Prog Neurobiol 2008;84:211-33
   PubMed Web of Science ®Google Scholar
• Schlichter LC, Kaushal V, Moxon-Emre I, et al. The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro. J Neuroinflammation 2010;7:4
   PubMed Web of Science ®Google Scholar
• Nijboer CH, Heijnen CJ, Groenendaal F, et al. Strong neuroprotection by inhibition of NF-kappaB after neonatal hypoxia-ischemia involves apoptotic mechanisms but is independent of cytokines. Stroke 2008;39:2129-3
   PubMed Web of Science ®Google Scholar
• Jin Y, Silverman AJ, Vannucci SJ. Mast cells are early responders after hypoxia-ischemia in immature rat brain. Stroke 2009;40:3107-12
   PubMed Web of Science ®Google Scholar
• Russell JC, Kishimoto K, O'Driscoll C, Hossain MA. Neuronal pentraxin 1 induction in hypoxic-ischemic neuronal death is regulated via a glycogen synthase kinase-3alpha/beta dependent mechanism. Cell Signal 2010;23:673-82
   PubMed Web of Science ®Google Scholar
• Rathmell JC, Thompson CB. The central effectors of cell death in the immune system. Annu Rev Immunol 1999;17:781-828
   PubMed Web of Science ®Google Scholar
• Dong Z, Saikumar P, Weinberg JM, Venkatachalam MA. Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases. Am J Pathol 1997;151(5):1205-13
   PubMed Web of Science ®Google Scholar
• Sup SJ, Green BG, Grant SK. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun 1994;204(2):962-8
   PubMed Web of Science ®Google Scholar
• Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998;281(5381):1305-8
   PubMed Web of Science ®Google Scholar
• Brown GC, Borutaite V. Nitric oxide, mitochondria, and cell death. IUBMB Life 2001;52(3-5):189-95
   PubMed Web of Science ®Google Scholar
• Crow JP, Beckman JS. The role of peroxynitrite in nitric oxide-mediated toxicity. Curr Top Microbiol Immunol 1995;196:57-73
   PubMedGoogle Scholar
• Wink DA, Mitchell JB. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic Biol Med 1998;25(4-5):434-56
   PubMed Web of Science ®Google Scholar
• Zhu C, Wang X, Qiu L, et al. Nitrosylation precedes caspase-3 activation and translocation of apoptosis-inducing factor in neonatal rat cerebral hypoxia-ischaemia. J Neurochem 2004;90(2):462-71
   PubMed Web of Science ®Google Scholar
• Dorrepaal CA, van Bel F, Moison RM, et al. Oxidative stress during post-hypoxic-ischemic reperfusion in the newborn lamb: the effect of nitric oxide synthesis inhibition. Pediatr Res 1997;41(3):321-6
   PubMed Web of Science ®Google Scholar
• Peeters-Scholte C, Koster J, van den Tweel E, et al. Effects of selective nitric oxide synthase inhibition on IGF-1, caspases and cytokines in a newborn piglet model of perinatal hypoxia-ischaemia. Dev Neurosci 2002;24(5):396-404
   PubMed Web of Science ®Google Scholar
• van den Tweel ER, van Bel F, Kavelaars A, et al. Long-term neuroprotection with 2-iminobiotin, an inhibitor of neuronal and inducible nitric oxide synthase, after cerebral hypoxia-ischemia in neonatal rats. J Cereb Blood Flow Metab 2005;25(1):67-74
   PubMed Web of Science ®Google Scholar
• Nijboer CH, Groenendaal F, Kavelaars A, et al. Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway. J Cereb Blood Flow Metab 2007;27(2):282-92
   PubMed Web of Science ®Google Scholar
• Bjorkman ST, Ireland Z, Fan X, et al. Short-term dose-response characteristics of 2-iminobiotin immediately postinsult in the neonatal piglet after hypoxia-ischemia. Stroke 2013;44(3):809-11
   PubMed Web of Science ®Google Scholar
• Van Bel F, Shadid M, Moison RM, et al. Effect of allopurinol on postasphyxial free radical formation, cerebral hemodynamics, and electrical brain activity. Pediatrics 1998;101(2):185-93
   PubMed Web of Science ®Google Scholar
• Kaandorp JJ, van Bel F, Veen S, et al. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials. Arch Dis Child Fetal Neonatal Ed 2012;97(3):F162-6
   PubMed Web of Science ®Google Scholar
• Derks JB, Oudijk MA, Torrance HL, et al. Allopurinol reduces oxidative stress in the ovine fetal cardiovascular system after repeated episodes of ischemia-reperfusion. Pediatr Res 2010;68(5):374-80
   PubMed Web of Science ®Google Scholar
• Balduini W, Carloni S, Perrone S, et al. The use of melatonin in hypoxic-ischemic brain damage: an experimental study. J Matern Fetal Neonatal Med 2012;25(Suppl 1):119-24
   PubMed Web of Science ®Google Scholar
• Elmahdy H, El-Mashad AR, El-Bahrawy H, et al. Human recombinant erythropoietin in asphyxia neonatorum: pilot trial. Pediatrics 2010;125:e1135-42
   PubMed Web of Science ®Google Scholar
• Zhu C, Kang W, Xu F, et al. Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy. Pediatrics 2009;124(2):e218-26
   PubMed Web of Science ®Google Scholar
• Khan M, Sekhon B, Jatana M, et al. Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci Res 2004;76:519-27
   PubMed Web of Science ®Google Scholar
• Yang L, Tan P, Zhou W, et al. N-acetylcysteine protects against hypoxia mimetic-induced autophagy by targeting the HIF-1α pathway in retinal ganglion cells. Cell Mol Neurobiol 2012;
   Web of Science ®Google Scholar
• Horowitz RS, Dart RC, Jarvie DR, et al. Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity. J Toxicol Clin Toxicol 1997;35(5):447-51
   PubMed Web of Science ®Google Scholar
• Ahola T, Lapatto R, Raivio KO, et al. N-acetylcysteine does not prevent bronchopulmonary dysplasia in immature infants: a randomized controlled trial. J Pediatr 2003;143(6):713-19
   PubMed Web of Science ®Google Scholar
• Perrone S, Negro S, Tataranno ML, Buonocore G. Oxidative stress and antioxidant strategies in newborns. J Matern Fetal Neonatal Med 2010;23(Suppl 3):63-5
   PubMed Web of Science ®Google Scholar
• Uttara B, Singh AV, Zamboni P, Mahajan RT. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009;7(1):65-74
   PubMed Web of Science ®Google Scholar
• Miller SL, Wallace EM, Walker DW. Antioxidant therapies: a potential role in perinatal medicine. Neuroendocrinology 2012;96(1):13-23
   PubMed Web of Science ®Google Scholar