60
Views
2
CrossRef citations to date
0
Altmetric
Drug Evaluations

Dexamethasone intravitreal implant (Allergan) for the treatment of noninfectious uveitis

, MD (Clinical Fellow in Uveitis and Ocular Inflammatory diseases) & , MD (Director Uveitis Service)

Bibliography

  • Addison T. On the constitutional and local effects of disease of the supra-renal capsules. New Sydenham Soc 1868;36:211-39
  • Hench PS, Kendall EC, Slocumb CH, et al. Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions. Arch Intern Med (Chic) 1950;85:545-666
  • Gordon DM, McLean JM, Koteen H. Present status of corticotropin; ACTH, cortisone, and hydrocortisone in ophthalmology. Br J Ophthalmol 1953;37:85-98
  • Gordon DM. Prednisone and prednisolone in ocular disease. Am J Ophthalmol 1956;41:593-600
  • Leopold IH, Sawyer JL, Green H. Intraocular penetration of locally applied steroids. AMA Arch Ophthalmol 1955;54:916-21
  • Gallant C, Kenny P. Oral glucocorticoids and their complications. A review. J Am Acad Dermatol 1986;14:161-77
  • Schimmer BP, Funder JW. ACTH, adrenal steroids, and pharmacology of the adrenal cortex. In: Brunton LL, Chabner BA, Knollmann BC, editors, Goodman & Gillman's the pharmacological basis of therapeutics. McGraw-Hill, New York; 2011
  • Melby JC. Clinical pharmacology of systemic corticosteroids. Annu Rev Pharmacol Toxicol 1977;17:511-27
  • Vadot E, Barth E, Billet P. Epidemiology of uveitis- preliminary results of a prospective study in Savoy. In: Saari K, editor, Uveitis update. Elsevier, Amsterdam; 1984. p. 13-16
  • Miettinen R. Incidence of uveitis in northern finland. Acta Ophthalmol (Copenh) 1977;55:252-60
  • Dandona L, Dandona R, John RK, et al. Population based assessment of uveitis in an urban population in southern India. Br J Ophthalmol 2000;84:706-9
  • Durrani OM, Tehrani NN, Marr JE, et al. Degree, duration, and causes of visual loss in uveitis. Br J Ophthalmol 2004;88:1159-62
  • Rothova A, Suttorp-van Schulten MS, Frits Treffers W, et al. Causes and frequency of blindness in patients with intraocular inflammatory disease. Br J Ophthalmol 1996;80:332-6
  • Nussenblatt RB. The natural history of uveitis. Int Ophthalmol 1990;14:303-8
  • Suttorp-Schulten MS, Rothova A. The possible impact of uveitis in blindness: a literature survey. Br J Ophthalmol 1996;80:844-8
  • Gritz DC, Wong IG. Incidence and prevalence of uveitis in northern california; the northern california epidemiology of uveitis study. Ophthalmology 2004;111:491-500
  • Wakefield D, Chang JH. Epidemiology of uveitis. Int Ophthalmol Clin 2005;45(2):1-13
  • Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of uveitis nomenclature for reporting clinical data. Results of the first international workshop. Am J Ophthalmol 2005;140:509-16
  • Yasukawa T, Ogura Y, Sakurai E, et al. Intraocular sustained drug delivery using implantable polymeric devices. Adv Drug Deliv Rev 2005;57(14):2033-46
  • Kwak HW, D'Amico DJ. Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection. Arch Ophthalmol 1992;110:259-66
  • Weijtens O, Schoemaker RC, Romijn FP, et al. Intraocular penetration and systemic absorption after topical application of dexamethasone disodium phosphate. Ophthalmology 2002;109:1887-91
  • Kuppermann BD, Blumenkranz MS, Haller JA, et al. Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema. Arch Ophthalmol 2007;125:309-17
  • Williams GA, Haller JA, Kuppermann BD, et al. Dexamethasone posterior-segment drug delivery system in the treatment of macular edema resulting from uveitis or irvine-gass syndrome. Am J Ophthalmol 2009;147:1048-54. 1054.e1-2
  • Lowder C, Belfort R Jr, Lightman S, et al. Dexamethasone intravitreal implant for noninfectious intermediate or posterior uveitis. Arch Ophthalmol 2011;129:545-53
  • Chang-Lin JE, Attar M, Acheampong AA, et al. Pharmacokinetics and pharmacodynamics of a sustained-release dexamethasone intravitreal implant. Invest Ophthalmol Vis Sci 2011;52:80-6
  • Lightman S, Belfort R Jr, Naik RK, et al. Vision-related functioning outcomes of dexamethasone intravitreal implant in noninfectious intermediate or posterior uveitis. Invest Ophthalmol Vis Sci 2013;54:4864-70
  • Gupta A, Ram J, Gupta A, Gupta V. Intraoperative dexamethasone implant in uveitis patients with cataract undergoing phacoemulsification. Ocul Immunol Inflamm 2013;21(6):462-7
  • Saraiya NV, Patel SS, Goldstein DA. A report of high intraocular pressure with the dexamethasone intravitreal implant. Arch Ophthalmol 2011;129:1638-9; author reply 1639-40
  • Meyer LM, Schonfeld CL. Secondary glaucoma after intravitreal dexamethasone 0.7 mg implant in patients with retinal vein occlusion: a one-year follow-up. J Ocul Pharmacol Ther 2013;29:560-5
  • Goldstein DA, Godfrey DG, Hall A, et al. Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants. Arch Ophthalmol 2007;125:1478-85
  • Capone A Jr, Singer MA, Dodwell DG, et al. Efficacy and safety of two or more dexamethasone intravitreal implant injections for treatment of macular edema related to retinal vein occlusion (shasta study). Retina 2014;34(2):342-51
  • Arcinue CA, Cerón OM, Foster CS. A comparison between the fluocinolone acetonide (retisert) and dexamethasone (dexamethasone implant) intravitreal implants in uveitis. J Ocul Pharmacol Ther 2013;29(5):501-7
  • Nguyen QD, Callanan D, Dugel P, et al. Treating chronic noninfectious posterior segment uveitis: the impact of cumulative damage. Proceedings of an expert panel roundtable discussion. Retina 2006;(Suppl):1-16
  • Callanan DG, Jaffe GJ, Martin DF, et al. Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results. Arch Ophthalmol 2008;126:1191-201
  • Kempen JH, Altaweel MM, Holbrook JT, et al. The multicenter uveitis steroid treatment trial: rationale, design, and baseline characteristics. Am J Ophthalmol 2010;149:550-61.e10
  • Kempen JH, Altaweel MM, Holbrook JT, et al. Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial. Ophthalmology 2011;118:1916-26
  • Lai WW, Pulido JS. Intermediate uveitis. Ophthalmol Clin North Am 2002;15:309-17
  • Forrester JV. Intermediate and posterior uveitis. Chem Immunol Allergy 2007;92:228-43
  • Kok H, Lau C, Maycock N, et al. Outcome of intravitreal triamcinolone in uveitis. Ophthalmology 2005;112:1916-e1-7
  • Sallam A, Taylor SR, Habot-Wilner Z, et al. Repeat intravitreal triamcinolone acetonide injections in uveitic macular oedema. Acta Ophthalmol 2012;90:e323-5
  • Zaborowski AG. Cytomegalovirus retinitis following intravitreal triamcinolone acetonide in a patient with chronic uveitis on systemic immunosuppression. Ocul Immunol Inflamm 2013;21(2):148-9
  • Vertes D, Snyers B, De Potter P. Cytomegalovirus retinitis after low-dose intravitreous triamcinolone acetonide in an immunocompetent patient: a warning for the widespread use of intravitreous corticosteroids. Int Ophthalmol 2010;30(5):595-7
  • Tugal-Tutkun I, Araz B, Cagatay A. CMV retinitis after intravitreal triamcinolone acetonide injection in a patient with Behçet's uveitis. Int Ophthalmol 2010;30(5):591-3
  • Delyfer MN, Rougier MB, Hubschman JP, et al. Cytomegalovirus retinitis following intravitreal injection of triamcinolone: report of two cases. Acta Ophthalmol Scand 2007;85(6):681-3
  • Shah AM, Oster SF, Freeman WR. Viral retinitis after intravitreal triamcinolone injection in patients with predisposing medical comorbidities. Am J Ophthalmol 2010;149(3):433-40
  • Ufret-Vincenty RL, Singh RP, Lowder CY, et al. Cytomegalovirus retinitis after fluocinolone acetonide (retisert) implant. Am J Ophthalmol 2007;143(2):334-5
  • Haller JA, Bandello F, Belfort R Jr, et al.; OZURDEX GENEVA Study Group. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology 2010;117(6):1134-46

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.