2,193
Views
3
CrossRef citations to date
0
Altmetric
Editorials

The Progeria Research Foundation: its remarkable journey from obscurity to treatment

&

Bibliography

  • Kieran MW, Gordon LB, Kleinman ME. The role of the farnesyltransferase inhibitor lonafarnib in the treatment of progeria. Exp Opin Orphan Drugs 2014;2:95-105
  • Gordon LB, Rothman FG, López-Otín C, Misteli T. Progeria: a paradigm for translational medicine. Cell 2014;156:400-7
  • Gilford H. Progeria: a form of senilism. The Practitioner; 1904. 188-217
  • De Sandre-Giovannoli A, Bernard R, Cau P, et al. Lamin a truncation in hutchinson-gilford progeria. Science 2003;300:2055
  • Eriksson M, Brown WT, Gordon L, et al. Recurrent de novo point mutations in lamin a cause hutchinson-gilford progeria syndrome. Nature 2003;423:293-7
  • Gordon LB. PRF by the numbers. Available from: www.progeriaresearch.org [Accessed 7 August 2014]
  • Gordon LB, Massaro J, D’Agostino RB, et al. Impact of farnesylation inhibitors on survival in hutchinson-gilford progeria syndrome. Circulation 2014
  • McClintock D, Ratner D, Lokuge M, et al. The mutant form of lamin a that causes hutchinson-gilford progeria is a biomarker of cellular aging in human skin. PloS One 2007;2:1-9
  • Olive M, Harten I, Mitchell R, et al. Cardiovascular pathology in hutchinson-gilford progeria: Correlation with the vascular pathology of aging. Arterioscler Thromb Vasc Biol 2010;30:2301-9
  • Gordon LB, McCarten KM, Giobbie-Hurder A, et al. Disease progression in hutchinson-gilford progeria syndrome: Impact on growth and development. Pediatrics 2007;120:824-33
  • Merideth MA, Gordon L, Clauss S, et al. Phenotype and course of hutchinson-gilford progeria syndrome. N Eng J Med 2008;358:592-604
  • Ullrich NJ, Kieran MW, Miller DT, et al. Neurologic features of hutchinson-gilford progeria syndrome after lonafarnib treatment. Neurology 2013;81:427-30
  • Gordon LB, Kleinman ME, Miller DT, et al. Clinical trial of a farnesyltransferase inhibitor in children with hutchinson-gilford progeria syndrome. Proc Natl Acad Sci USA 2012;109:16666-71
  • Hutchinson J. Congenital absence of hair and mammary glands with atrophic condition of the skin and its appendages in a boy whose mother had been almost wholly bald from alopecia areata from the age of six. Med Chir Trans 1886;69:473-7
  • Scaffidi P, Misteli T. Lamin a-dependent nuclear defects in human aging. Science 2006;312:1059-63

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.