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Drug Profile

Docetaxel in the management of ovarian cancer

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Pages 203-214 | Published online: 10 Jan 2014

References

  • Guastalla JP III, Dieras V. The taxanes: toxicity and quality of life considerations in advanced ovarian cancer. Br. J. Cancer 89(Suppl. 3), S16–S22 (2003).
  • Vasey PA, Paul J, Birt A et al. Docetaxel and cisplatin in combination as first-line chemotherapy for advanced epithelial ovarian cancer. J. Clin. Oncol. 17, 2069–2080 (1999).
  • Vasey PA, Jayson GC, Gordon A et al. Scottish Gynaecological Cancer Trials Group. Phase III randomized trial of docetaxel–carboplatin versus paclitaxel–carboplatin as first-line chemotherapy for ovarian carcinoma. J. Natl Cancer Inst. 96(22), 1682–1691 (2004).
  • Young RC, Perez CA, Hoskins WJ. Cancer of the ovary. In: Cancer: Principles and Practice of Oncology, 4th edition. deVita VT, Hellman S, Rosenberg SA (Eds), JB Lippincott Co., PA, USA, 1226–1263 (1993).
  • Verschraegen CF, Sittisomwong T, Kudelka AP et al. Docetaxel for patients with paclitaxel-resistant Müllerian carcinoma. J. Clin. Oncol. 18(14), 2733–2739 (2000).
  • New PZ, Jackson CE, Rinaldi D, Burris H, Barohn RJ. Peripheral neuropathy secondary to docetaxel (Taxotere). Neurology 46(1), 108–111 (1996).
  • Cragg GM, Boyd MR, Cardellina JH II, Newman DJ, Snader KM, McCloud TG. Ethnobotany and drug discovery: the experience of the US National Cancer Institute. CIBA Found. Symp. 185, 178–190 (1994).
  • Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by Taxol. Nature 277(5698), 665–667 (1980).
  • Denis JN, Correa A, Greene AE. An improved synthesis of the Taxol side chain and of RP 56976. J. Org. Chem. 55, 1957–1959 (1990).
  • Mastropaolo D, Camerman A, Luo Y, Brayer GD, Camerman N. Crystal and molecular structure of paclitaxel (Taxol). Proc. Natl Acad. Sci. USA 92, 6920–6924 (1995).
  • Lam YW, Chan CY, Kuhn JG. Pharmacokinetics and pharmacodynamics of the taxanes. J. Clin. Pharm. Pract. 3, 76–93 (1997).
  • Hanauske AR, Degen D, Hilsenbeck SG et al. Effects of Taxotere and Taxol on in vitro colony formation of freshly explanted human tumor cells. Anticancer Drugs 3, 121–124 (1992).
  • Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nature Rev. Cancer 4(4), 253–265 (2004).
  • Garcia P, Braguer D, Carles G et al. Comparative effects of Taxol and Taxotere on two different human carcinoma cell lines. Cancer Chemother. Pharmacol. 34(4), 335–343 (1994).
  • Ringel I, Horwitz SB. Studies with RP 56976 (Taxotere): a semisynthetic analogue of Taxol. J. Natl Cancer Inst. 83(4), 288–291 (1991).
  • Dumontet C, Sikic BI. Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death. J. Clin. Oncol. 17(3), 1061–1070 (1999).
  • Hennequin C, Giocanti N, Favaudon V. S-phase specificity of cell killing by docetaxel (Taxotere) in synchronised HeLa cells. Br. J. Cancer 71(6), 1194–1198 (1995).
  • Miller ML, Ojima I. Chemistry and chemical biology of taxane anticancer agents. Chem. Rec. 1(3), 195–211 (2001).
  • Gligorov J, Lotz JP. Preclinical pharmacology of the taxanes: implications of the differences. Oncologist 9(Suppl. 2), 3–8 (2004).
  • Grant DS, Williams TL, Zahaczewsky M, Dicker AP. Comparison of anti-angiogenic activities using paclitaxel (Taxol) and docetaxel (Taxotere) Int. J. Cancer 104, 121–129 (2003).
  • Moos PJ, Fitzpatrick FA. Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis. Proc. Natl Acad. Sci. USA 95(7), 3896–3901 (1998).
  • Rigas JR. Taxane–platinum combinations in advanced non-small cell lung cancer: a review. Oncologist 9(Suppl. 2), 16–23 (2004).
  • Synold TW, Dussault I, Forman BM. The orphan nuclear receptor SXR co-ordinately regulates drug metabolism and efflux. Nature Med. 7(5), 584–590. (2001).
  • Extra JM, Rousseau F, Bruno R, Clavel M, Le Bail N, Marty M. Phase I and pharmacokinetic study of Taxotere (RP 56976; NSC 628503) given as a short intravenous infusion. Cancer Res. 53(5), 1037–1042 (1993).
  • van Tellingen O, Huizing MT, Panday VR, Schellens JH, Nooijen WJ, Beijnen JH. Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients. Br. J. Cancer 81(2), 330–335 (1999).
  • Riou JF, Petitgenet O, Combeau C et al. Cellular uptake and efflux of docetaxel (Taxotere®) and paclitaxel (Taxol®) in P388 cell line. Proc. Am. Assoc. Cancer Res. 35, 385 (1994) (Abstract 2292).
  • Pazdur R, Newman RA, Newman BA et al. Phase I trial of Taxotere: five-day schedule. J. Natl Cancer Inst. 84(23), 1781–1786 (1992).
  • de Valeriola D, Brassinne C, Piccart M et al. Phase I and pharmacokinetic study of Taxotere as a weekly infusion. Proc. Am. Assoc. Cancer Res. 33, 261 (1992).
  • Cortes JE, Pazdur R. Docetaxel. J. Clin. Oncol. 13, 2643–2655 (1995).
  • Burris H, Irvin R, Kuhn J et al. Phase I clinical trial of Taxotere administered as either a 2-hour or 6-hour intravenous infusion. J. Clin. Oncol. 11(5), 950–958 (1993).
  • Bissett D, Setanoians A, Cassidy J et al. Phase I and pharmacokinetic study of Taxotere (RP 56976) administered as a 24-hour infusion. Cancer Res. 53(3), 523–527 (1993).
  • Hong WK. The current status of docetaxel in solid tumors. An MD Anderson Cancer Center Review. Oncology (Huntingt.) 16(6 Suppl. 6), 9–15 (2002).
  • Ravdin P, Erban J, Overmoyer B et al. Phase III comparison of docetaxel (D) and paclitaxel (P) in patients with metastatic breast cancer (MBC). Eur. J. Cancer 1(Suppl. 5), S201 (2003).
  • Petrylak DP, Tangen CM, Hussain MH et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N. Engl. J. Med. 351(15), 1513–1520 (2004).
  • Tannock IF, de Wit R, Berry WR et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. 351(15), 1502–1512 (2004).
  • McGuire WP, Hoskins WJ, Brady MF et al. Cyclophosphamide and cisplatin versus paclitaxel and cisplatin: a Phase III randomized trial in patients with sub optimal Stage III/IV ovarian cancer (from the Gynecologic Oncology Group). Semin. Oncol. 23(5 Suppl. 12), 40–47 (1996).
  • Piccart MJ, Bertelsen K, James K et al. Randomized intergroup trial of cisplatin–paclitaxel versus cisplatin–cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results. J. Natl Cancer Inst. 92(9), 699–708 (2000).
  • Muggia FM, Braly PS, Brady MF et al. Phase III randomised study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal Stage III or IV ovarian cancer: a Gynaecologic Oncology Group study. J. Clin. Oncol. 18, 106–115 (2000).
  • Harper P, on behalf of the ICON Collaborators. A randomised comparison of paclitaxel (T) and carboplatin (J) versus a control arm of single agent carboplatin (J) or CAP (cyclophosphamide, doxorubicin and cisplatin): 2075 patients randomised into the third International Collaborative Ovarian Neoplasm Study (ICON3). Proc. Am. Soc. Clin. Oncol. 18, 356a (1999) (Abstract 1375).
  • Colombo N. Randomised trial of paclitaxel (PTX) and carboplatin (CBDCA) versus a control arm of carboplatin or CAP (cyclophosphamide, doxorubicin and cisplatin): the Third International Collaborative Ovarian Neoplasm Study (ICON3). Proc. Am. Soc. Clin. Oncol. (2000) (Abstract 1500).
  • Sandercock J, Parmar MKB, Torri V, Qian W. First-line treatment for advanced ovarian cancer: paclitaxel, platinum and the evidence. Br. J. Cancer 87, 815–824 (2002).
  • Bunn PA Jr, Kelly K. New chemotherapeutic agents prolong survival and improve quality of life in non-small cell lung cancer: a review of the literature and future directions. Clin. Cancer Res. 4(5), 1087–1100 (1998).
  • Calabro F, Sternberg CN. New drugs and new approaches for the treatment of metastatic urothelial cancer. World J. Urol. 20(3), 158–166 (2002).
  • Aabo K, Adams M, Adnitt P et al. Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists’ Group. Br. J. Cancer 78(11), 1479–1487(1998).
  • Neijt JP, Engelholm SA, Tuxen MK et al. Exploratory Phase III study of paclitaxel and cisplatin versus paclitaxel and carboplatin in advanced ovarian cancer. J. Clin. Oncol. 18(17), 3084–3092 (2000).
  • du Bois A, Luck HJ, Meier W et al. A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer. J. Natl Cancer Inst. 95(17), 1320–1329 (2003).
  • Ozols RF, Bundy BN, Greer BE et al. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected Stage III ovarian cancer: a Gynecologic Oncology Group study. J. Clin. Oncol. 21(17), 3194–3200 (2003).
  • Slichenmyer WJ, Von Hoff DD. Taxol: a new and effective anticancer drug. Anticancer Drugs 2(6), 519–530 (1991).
  • McNally OM, Delaney E, Petty RD, Cruickshank ME, Hutcheon AW, Parkin DE. Is optimal first-line chemotherapy deliverable in all newly diagnosed ovarian cancers? A population-based study. Br. J. Cancer 89(6), 966–967 (2003).
  • Eisenhauer EA, Vermorken JB, van Glabbeke M. Predictors of response to subsequent chemotherapy in platinum pretreated ovarian cancer: a multivariate analysis of 704 patients. Ann. Oncol. 8(10), 963–968 (1997).
  • Parmar MK, Ledermann JA, Colombo N et al. Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial. Lancet 361(9375), 2099–2106 (2003).
  • Pfisterer J, Plante M, Vergote I et al. Gemcitabine/carboplatin (GC) vs. carboplatin (C) in platinum sensitive recurrent ovarian cancer (OVCA). Results of a gynaecologic cancer intergroup randomized Phase III trial of the AGO OVAR, the NCIC CTG and the EORTC GCG. Proc. Am. Soc. Clin. Oncol. 22(14S) (2004) (Abstract 5005).
  • Harries M, Gore M. Part II: chemotherapy for epithelial ovarian cancer – treatment of recurrent disease. Lancet Oncol. 3(9), 537–545 (2002).
  • Kaern J, Baekelandt M, Trope CG. A Phase II study of weekly paclitaxel in platinum and paclitaxel-resistant ovarian cancer patients. Eur. J. Gynaecol. Oncol. 23(5), 383–389 (2002).
  • Aapro M, Bruno R. Early clinical studies with docetaxel. Docetaxel Investigators Group. Eur. J. Cancer 31A(Suppl. 4), S7–S10 (1995).
  • Piccart MJ, Gore M, Ten Bokkel Huinink W et al. Docetaxel: an active new drug for treatment of advanced epithelial ovarian cancer. J. Natl Cancer Inst. 87(9), 676–681 (1995).
  • Francis P, Schneider J, Hann L et al. Phase II trial of docetaxel in patients with platinum-refractory advanced ovarian cancer. J. Clin. Oncol. 12(11), 2301–2308 (1994).
  • Kavanagh JJ, Kudelka AP, de Leon CG et al. Phase II study of docetaxel in patients with epithelial ovarian carcinoma refractory to platinum. Clin. Cancer Res. 2(5), 837–842 (1996).
  • Kaye SB, Piccart M, Aapro M, Francis P, Kavanagh J. Phase II trials of docetaxel (Taxotere) in advanced ovarian cancer – an updated overview. Eur. J. Cancer 33, 2167–2170 (1997).
  • Schrijvers D, Wanders J, Dirix L et al. Coping with toxicities of docetaxel (Taxotere). Ann. Oncol. 4(7), 610–611 (1993).
  • Kaye SB, Scottish Gynaecological Cancer Trials Group. The integration of docetaxel into first-line chemotherapy for ovarian cancer. Int. J. Gynaecol. Cancer 11, 31–33 (2001).
  • Dieras V, Guastalla JP, Ferrero JM et al. A multicenter Phase II study of cisplatin and docetaxel (Taxotere) in the first-line treatment of advanced ovarian cancer: a GINECO study. Cancer Chemother. Pharmacol. 53(6), 489–495 (2004).
  • Vasey PA, Atkinson R, Coleman R et al. Docetaxel–carboplatin as first line chemotherapy for epithelial ovarian cancer. Br. J. Cancer 84(2), 170–178 (2001).
  • Katsimbri P, Bamias A, Pavlidis N. Prevention of chemotherapy-induced alopecia using an effective scalp cooling system. Eur. J. Cancer 36(6), 766–771 (2000).
  • Hsu Y, Sood AK, Sorosky JI. Docetaxel versus paclitaxel for adjuvant treatment of ovarian cancer: case-control analysis of toxicity. Am. J. Clin. Oncol. 27(1), 14–18 (2004).
  • Rustin GJ, Atkinson RA, Osborne R et al. Preliminary results of SCOTROC 2A, a randomised feasibility study of carboplatin (C) then sequential docetaxel (D) or two schedules of docetaxel + gemcitabine (G) in ovarian/Müllerian cancers Proc. Am. Soc. Clin. Oncol. (2002) (Abstract 810).
  • Vasey P, Atkinson R, Osborne R et al. Carboplatin (Cb) followed sequentially by docetaxel (D) ± gemcitabine (G) in ovarian, peritoneal and fallopian tube cancers. Results of SCOTROC 2A. Proc. Am. Soc. Clin. Oncol. 22(449) (2003) (Abstract 1804).
  • Jayson GC, Maenpaa J, Wilkinson PM et al. Randomized feasibility study of carboplatin followed by docetaxel or docetaxel/irinotecan in ovarian cancer (SCOTROC IIB). Proc. Am. Soc. Clin. Oncol. 22(449) (2003) (Abstract 1805).
  • Agarwal R, Kaye S, Vasey P et al. Erlotinib (E) in combination with docetaxel (D) and carboplatin (C): a Phase Ib trial in patients with untreated ovarian, fallopian tube and primary peritoneal cancers. Ann. Oncol. 15(20) (2004) (Abstract 475).
  • Untch M, Untch A, Sevin BU et al. Comparison of paclitaxel and docetaxel (Taxotere) in gynecologic and breast cancer cell lines with the ATP-cell viability assay. Anticancer Drugs 5(1), 24–30 (1994).
  • Valero V, Jones SE, Von Hoff DD et al. A Phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer. J. Clin. Oncol. 16(10), 3362–3368 (1998).
  • Rose PG, Blessing JA, Ball HG et al. A Phase II study of docetaxel in paclitaxel-resistant ovarian and peritoneal carcinoma: a Gynaecologic Oncology Group study. Gynaecol. Oncol. 88(2), 130–135 (2003).
  • Kavanagh JJ, Winn R, Steger M et al. Docetaxel for patients with ovarian cancer refractory to paclitaxel, an update. Proc. Am. Soc. Clin. Oncol. 18, 368a (1999) (Abstract 1423).
  • Verschraegen CF, Sittisomwong T, Kudelka AP et al. Docetaxel for patients with paclitaxel-resistant Müllerian carcinoma. J. Clin. Oncol. 18, 2733–2739 (2000).
  • Hirth J, Watkins PB, Strawderman M, Schott A, Bruno R, Baker LH. The effect of an individual’s cytochrome cYP3A4 activity on docetaxel clearance. Clin. Cancer Res. 6(4), 1255–1258 (2000).
  • McNeil C. Herceptin raises its sights beyond advanced breast cancer. J. Natl Cancer Inst. 90(12), 882–883 (1998).
  • Pegram MD, Lopez A, Konecny G, Slamon DJ. Trastuzumab and chemotherapeutics: drug interactions and synergies. Semin. Oncol. 27(6 Suppl. 11), 21–25 (2000).
  • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785), 177–182 (1987).
  • Slamon DJ, Godolphin W, Jones LA et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244(4905), 707–712 (1989).
  • Bookman MA, Darcy KM, Clarke-Pearson D, Boothby RA, Horowitz IR. Evaluation of monoclonal humanized antiHER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a Phase II trial of the Gynecologic Oncology Group. J. Clin. Oncol. 21(2), 283–290 (2003).
  • Chatta GS, Fakih M, Ramalingam S et al. Phase I pharmacokinetic (PK) study of daily imatinib in combination with docetaxel for patients with advanced solid tumors. Proc. Am. Soc. Clin. Oncol. 22, 14S (2004) (Abstract 2047).
  • Overmoyer B, Silverman P, Leeming R et al. Phase II trial of neoadjuvant docetaxel with or without bevacizumab in patients with locally advanced breast cancer. Proc. Am. Soc. Clin. Oncol. 22, 14S (2004) (Abstract 727).
  • Forero L, Patnaik A, Hammond LA et al. Phase I, pharmacokinetic (PK) and biologic study of OSI-774, a selective epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor in combination with paclitaxel and carboplatin. Proc. Am. Soc. Clin. Oncol. (2002) (Abstract 1908).
  • Reid T, Weeks A, Vakil M et al. Dose escalation study of pivanex (a histone deacetylase inhibitor) in combination with docetaxel for advanced non-small cell lung cancer. Proc. Am. Soc. Clin. Oncol. 22, 14S (2004) (Abstract 7279).
  • Messersmith WA, Baker SD, Dinh K et al. Phase I trial of bortezomib (PS-341) in combination with docetaxel in patients with advanced solid tumors. Proc. Am. Soc. Clin. Oncol. 22, 14S (2004) (Abstract 3052).
  • Rathkopf D, Fornier M, Shah M et al. A Phase I dose finding study of weekly, sequential docetaxel (Doc) followed by flavopiridol (F) in patients with advanced solid tumors. Proc. Am. Soc. Clin. Oncol. 22, 14S (2004) (Abstract 3072).
  • Pietras K, Stumm M, Hubert M et al. STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake. Clin. Cancer Res. 9(10 Pt 1), 3779–3787 (2003).
  • Kim SJ, Uehara H, Yazici S et al. Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice. Cancer Res. 64(12), 4201–4208 (2004).
  • Dranitsaris G, Elia-Pacitti J, Cottrell W. Measuring treatment preferences and willingness to pay for docetaxel in advanced ovarian cancer. Pharmacoeconomics 22(6), 375–387 (2004).
  • Roila F, Cortesi E. Quality of life as a primary end point in oncology. Ann. Oncol. 12(Suppl. 3), S3–S6 (2001).
  • Fulton B, Spencer CM. Docetaxel. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of metastatic breast cancer. Drugs 51(6), 1075–1092 (1996).
  • Hilkens PH, Verweij J, Vecht CJ, Stoter G, van den Bent MJ. Clinical characteristics of severe peripheral neuropathy induced by docetaxel (Taxotere). Ann. Oncol. 8(2), 187–190 (1997).
  • Verstappen CC, Heimans JJ, Hoekman K, Postma TJ. Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management. Drugs 63(15), 1549–1563 (2003).
  • Rose PG, Smrekar M. Improvement of paclitaxel-induced neuropathy by substitution of docetaxel for paclitaxel. Gynecol. Oncol. 91(2), 423–425 (2003).
  • Hagiwara H, Sunada Y. Mechanism of taxane neurotoxicity. Breast Cancer 11(1), 82–85 (2004).
  • Aaronson NK, Ahmedzai S, Bergman B et al.The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J. Natl Cancer Inst. 85(5), 365–376 (1993).
  • Cull A, Howat S, Greimel E et al. Development of a European organisation for research and treatment of cancer questionnaire module to address the quality of life of ovarian cancer patients in clinical trials: a progress report. Eur. J. Cancer 37, 47–53 (2001).

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