References
- ENCODE Project Consortium, Dunham I, Kundaje A, Aldred SF et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489(7414), 57–74 (2012).
- Djebali S, Davis CA, Merkel A et al. Landscape of transcription in human cells. Nature 489, 101–108 (2012).
- Maurano MT, Humbert R, Rynes E et al. Systematic localization of common disease-associated variation in regulatory DNA. Science 337(6099), 1190–1195 (2012).
- Gerstein MB, Kundaje A, Hariharan M et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489(7414), 91–100 (2012).
- Neph S, Vierstra J, Stergachis AB et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 489(7414), 83–90 (2012).
- Sanyal A, Lajoie BR, Jain G, Dekker J. The long-range interaction landscape of gene promoters. Nature 489, 109–113 (2012).
- Yosef N, Shalek AK, Gaublomme JT. Dynamic regulatory network controlling TH17 cell differentiation. Nature 496(7446), 461–468 (2013).
- Stamatoyannopoulos JA. What does our genome encode? Genome Res. 22(9), 1602–1611 (2012).
- Roukos DH. Disrupting cancer cells’ biocircuits with interactome-based drugs: is ‘clinical’ innovation realistic? Expert Rev. Proteomics 9(4), 349–353 (2012).
- Li MJ, Wang P, Liu X et al. GWASdb: a database for human genetic variants identified by genome-wide association studies. Nucleic Acids Res. 40( Database issue),D1047–D1054 (2012).
- 1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD et al. An integrated map of genetic variation from 1,092 human genomes. Nature 491(7422), 56–65 (2012).
- Janjić V, Pržulj N. Biological function through network topology: a survey of the human diseasome. Brief. Funct. Genomics 11(6), 522–532 (2012).
- Rask-Andersen M, Almén MS, Schiöth HB. Trends in the exploitation of novel drug targets. Nat. Rev. Drug Discov. 10(8), 579–590 (2011).
- Barabási AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nat. Rev. Genet. 12, 56–68 (2011).
- Schaub MA, Boyle AP, Kundaje A, Batzoglou S, Snyder M. Linking disease associations with regulatory information in the human genome. Genome Res. 22(9), 1748–1759 (2012).
- Neph S, Stergachis AB, Reynolds A, Sandstrom R, Borenstein E, Stamatoyannopoulos JA. Circuitry and dynamics of human transcription factor regulatory networks. Cell 150(6), 1274–1286 (2012).
- Cheng TM, Gulati S, Agius R, Bates PA. Understanding cancer mechanisms through network dynamics. Brief. Funct. Genomics 11(6), 543–560 (2012).
- Zhang QC, Petrey D, Garzón JI, Deng L, Honig B. PrePPI: a structure-informed database of protein-protein interactions. Nucleic Acids Res. 41(D1), D828–D833 (2013).
- He Y, Fang J, Taatjes DJ, Nogales E. Structural visualization of key steps in human transcription initiation. Nature 495, 481–486 (2013).
- Nair VS, Maeda LS, Ioannidis JP. Clinical outcome prediction by microRNAs in human cancer: a systematic review. J. Natl. Cancer Inst. 104(7), 528–540 (2012).
- Frankish JA, Gonzalez JM. GENCODE: The reference human genome annotation for The ENCODE Project. Genome Res. 22(9), 1760–1774 (2012).
- Roukos DH, Ziogas DE, Baltogiannis GG. Novel next-generation sequencing and networks-based therapeutic targets: realistic more effective drug design and discovery. Curr. Pharm. Des. (2013) ( In Press).
- Fernãndez A, Lynch M. Non-adaptive origins of interactome complexity. Nature 18(7352), 474502–474505 (2011).
- Chung K, Wallace J, Kim SY. Structural and molecular interrogation of intact biological systems. Nature 497, 332–337 (2013).