References
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- Williams-Jones B. Where there's a web, there's a way: commercial genetic testing and the Internet. Community Genet. 6(1), 46–57 (2003).
- Guttmacher AE, Collins FS. Genomic medicine — a primer. N. Engl. Med. 347(19), 1512–1520 (2002).
- Campbell AM, Heyer L.J. Discovering Genomics, Proteomics and Bioinfonnatics. CSHL Press, CA, USA, 3 (2003).
- Burke W Genetic testing. N Engl. I Med. 347(23), 1867–1875 (2002).
- Evans JP, Skrzynia C, Burke W The complexities of predictive genetic testing. BE Med. 322(7293), 1052–1056 (2001).
- Khoury MJ, McCabe LL, McCabe ERB. Population screening in the age of genomic medicine. N Engl. J. Med. 348(1), 50–58 (2003).
- ••Useful article to put into perspective thevarious types of DNA screening options available.
- Weinshilboum R. Inheritance and drug response. N. Engl. J Med. 348(6), 529–537 (2003).
- Grody WW Molecular genetic risk screening. Ann. Rev Med. 54,473–490 (2003).
- Higashi MK, Veenstra DL, Kondo LM eta]. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAIVIA 287(13), 1690–1698 (2002).
- ••Provides good insight into futurepersonalized medicine type of DNA testing.
- Burke W, Pinsky LA, Press NA. Categorizing genetic tests to identify their ethical, legal and social implications. Am. Med. Genet. 106(3), 233–240 (2001).
- Haga S, Khoury MJ, Burke W Genomic profiling to promote a health lifestyle: not ready for prime time. Nature Genet. 34(4), 347–350 (2003).
- •Illustrates the potential negative aspects of DNA testing if used inappropriately and that there is little community understanding of the significance of the DNA test.
- Trent RJ. Molecular Medicine — an Introductory Text. Churchill Livingstone, Edinburgh, UK, 212 (1997).
- Van de Vijver MJ, He YD, van'T Veer LJ eta]. A gene expression signature as a predictor of survival in breast cancer. N. Engl. Med. 347(25), 1999–2009 (2002).
- •Key early article showing how microarray technology will impact on clinical practice.
- Collins FS, Green ED, Guttmacher AE, Guyer MS. A vision for the future of genomics research. Nature 422(6934), 835–847 (2003).
- •Any article by Francis Collins is worthwhile reading. This one makes insightful predictions for the future.
- Ratner M, Ratner D. Nanotechnology. a Gentle Introduction to the Next Big Idea.Prentice Hall, NJ, USA, 102–106 (2003).
- ••Provides insight into an area of technology which would not normally be understood by the geneticist.
- Bayat A. Science, medicine and the future: bioinformatics. BE Med. J. 324(7344), 1018–1022 (2002).
- Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex disease. Nature Genet. Suppl 33,228–237 (2003).
- Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD. Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes. Am. Hum. Genet. 72(3), 636–649 (2003).
- Emery J, Walton R, Murphy M et al Computer support for interpreting family histories of breast and ovarian cancer in primary care: comparative study with simulated cases. BE Med J. 321(7252), 28–32 (2000).
- •Although illustrating a straightforward example, this article illustrates the likely impact that computer-based algorithms will have on clinical decision making in genetics.
- Clayton EW. Ethical, legal and social implications of genomic medicine. N. Engl. Med. 349(6), 562–569 (2003).
Websites
- LocusLink www.ncbi.nlm.nih.gov/LocusLink/ RSstatistics.html (Viewed February 2004)
- GeneTests www.geneclinics.org (Viewed February 2004)
- Gendia www.gendia.net (Viewed February 2004)
- Genovations www.genovations.com (Viewed February 2004)
- Australian Law Reform Commission www.alrc.gov.au (Viewed February 2004)
- Nanosphere www.nanosphere-inc.com/index.html (Viewed February 2004)
- Online Mendelian Inheritance in Man www.ncbi.nlm.nih.gov/Omim (Viewed February 2004)
- •Reputable and up-to-date compendium on genetic diseases.
- National Coalition for Health Professional Education in Genetics www.nchpeg.org (Viewed February 2004)
- National Newborn Screening and Genetics Resource Center http://genes-r-us.uthscsa.edu/resources/ genetics/primary_care.htm (Viewed February 2004)
- Genetic Technologies www.gtg.com.au (Viewed February 2004) iii Nuffield Council on Bioethics www.nuffieldbioethics.org/home (Viewed February 2004)
- The Human Genome Organisation www.hugo-international.org/hugo (Viewed February 2004) Affiliations