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Rituximab in the treatment of peripheral neuropathy associated with monoclonal gammopathy

Pages 1267-1274 | Published online: 10 Jan 2014

References

  • Kyle RA, Therneau TM, Rajkumar SV et al. Prevalence of monoclonal gammopathy of undetermined significance. N. Engl. J. Med.354(13), 1362–1369 (2006).
  • Kelly JJ Jr, Kyle RA, O’Brien PC, Dyck PJ. Prevalence of monoclonal protein in peripheral neuropathy. Neurology31(11), 1480–1483 (1981).
  • Latov N. Pathogenesis and therapy of neuropathies associated with monoclonal gammopathies. Ann. Neurol.37(Suppl. 1), S32–S42 (1995).
  • Gorson KC, Ropper AH, Weinberg DH, Weinstein R. Treatment experience in patients with anti-myelin-associated glycoprotein neuropathy. Muscle Nerve24(6), 778–786 (2001).
  • Freddo L, Ariga T, Saito M et al. The neuropathy of plasma cell dyscrasia: binding of IgM M-proteins to peripheral nerve glycolipids. Neurology35(10), 1420–1424 (1985).
  • Vital A, Vital C, Julien J, Baquey A, Steck AJ. Polyneuropathy associated with IgM monoclonal gammopathy. Immunological and pathological study in 31 patients. Acta Neuropathol.79(2), 160–167 (1989).
  • Van den Berg L, Hays AP, Nobile-Orazio E et al. Anti-MAG and anti-SGPG antibodies in neuropathy. Muscle Nerve19(5), 637–643 (1996).
  • Weiss MD, Dalakas MC, Lauter CJ, Willison HJ, Quarles RH. Variability in the binding of anti-MAG and anti-SGPG antibodies to target antigens in demyelinating neuropathy and IgM paraproteinemia. J. Neuroimmunol.95(1–2), 174–184 (1999).
  • Hays AP, Latov N, Takatsu M, Sherman WH. Experimental demyelination of nerve induced by serum of patients with neuropathy and an anti-MAG IgM M-protein. Neurology37(2), 242–256 (1987).
  • Ilyas AA, Quarles RH, Dalakas MC, Brady RO. Polyneuropathy with monoclonal gammopathy: glycolipids are frequently antigens for IgM paraproteins. Proc. Natl Acad. Sci. USA82(19), 6697–6700 (1985).
  • Eurelings M, Moons KG, Notermans NC et al. Neuropathy and IgM M-proteins: prognostic value of antibodies to MAG, SGPG, and sulfatide. Neurology56(2), 228–233 (2001).
  • Nobile-Orazio E, Meucci N, Baldini L, Di Troia A, Scarlato G. Long-term prognosis of neuropathy associated with anti-MAG IgM M-proteins and its relationship to immune therapies. Brain123(Pt 4), 710–717 (2000).
  • Gosselin S, Kyle RA, Dyck PJ. Neuropathy associated with monoclonal gammopathies of undetermined significance. Ann. Neurol.30(1), 54–61 (1991).
  • Trojaborg W, Hays AP, van den Berg L, Younger DS, Latov N. Motor conduction parameters in neuropathies associated with anti-MAG antibodies and other types of demyelinating and axonal neuropathies. Muscle Nerve18(7), 730–735 (1995).
  • Magy L, Chassande B, Maisonobe T et al. Polyneuropathy associated with IgG/IgA monoclonal gammopathy: a clinical and electrophysiological study of 15 cases. Eur. J. Neurol.10(6), 677–685 (2003).
  • Simmons Z, Bromberg MB, Feldman EL, Blaivas M. Polyneuropathy associated with IgA monoclonal gammopathy of undetermined significance. Muscle Nerve16(1), 77–83 (1993).
  • Simovic D, Gorson KC, Ropper AH. Comparison of IgM-MGUS and IgG-MGUS polyneuropathy. Acta Neurol. Scand.97(3), 194–200 (1998).
  • Kornberg AJ, Pestronk A. Antibody-associated polyneuropathy syndromes: principles and treatment. Semin. Neurol.23(2), 181–190 (2003).
  • Notermans NC, Lokhorst HM, Franssen H et al. Intermittent cyclophosphamide and prednisone treatment of polyneuropathy associated with monoclonal gammopathy of undetermined significance. Neurology47(5), 1227–1233 (1996).
  • Mariette X, Chastang C, Clavelou P et al. A randomised clinical trial comparing interferon-alpha and intravenous immunoglobulin in polyneuropathy associated with monoclonal IgM. The IgM-associated Polyneuropathy Study Group. J. Neurol. Neurosurg. Psychiatr.63(1), 28–34 (1997).
  • Cook D, Dalakas M, Galdi A, Biondi D, Porter H. High-dose intravenous immunoglobulin in the treatment of demyelinating neuropathy associated with monoclonal gammopathy. Neurology40(2), 212–214 (1990).
  • Oksenhendler E, Chevret S, Leger JM et al. Plasma exchange and chlorambucil in polyneuropathy associated with monoclonal IgM gammopathy. IgM-associated Polyneuropathy Study Group. J. Neurol. Neurosurg. Psychiatr.59(3), 243–247 (1995).
  • Latov N, Sherman WH. Therapy of neuropathy associated with anti-MAG IgM monoclonal gammopathy with rituxan. Neurology52(Suppl. 2), A551 (1999).
  • Levine TD, Pestronk A. IgM antibody-related polyneuropathies: B-cell depletion chemotherapy using rituximab. Neurology52(8), 1701–1704 (1999).
  • Pestronk A, Florence J, Miller T et al. Treatment of IgM antibody associated polyneuropathies using rituximab. J. Neurol. Neurosurg. Psychiatr.74(4), 485–489 (2003).
  • Renaud S, Gregor M, Fuhr P et al. Rituximab in the treatment of polyneuropathy associated with anti-MAG antibodies. Muscle Nerve27(5), 611–615 (2003).
  • Siddiqui K, Cahalane E, Keogan M, Hardiman O. Chronic ataxic neuropathy with cold agglutinins: atypical phenotype and response to anti-CD20 antibodies. Neurology61(9), 1307–1308 (2003).
  • Briani C, Zara G, Zambello R et al. Rituximab-responsive CIDP. Eur. J. Neurol.11(11), 788 (2004).
  • Goldfarb AR, Weimer LH, Brannagan TH 3rd. Rituximab treatment of an IgM monoclonal autonomic and sensory neuropathy. Muscle Nerve31(4), 510–515 (2005).
  • Cai FZ, Ahern M, Smith M. Treatment of cryoglobulinemia associated peripheral neuropathy with rituximab. J. Rheumatol.33(6), 1197–1198 (2006).
  • Kilidireas C, Anagnostopoulos A, Karandreas N, Mouselimi L, Dimopoulos MA. Rituximab therapy in monoclonal IgM-related neuropathies. Leuk. Lymphoma47(5), 859–864 (2006).
  • Renaud S, Fuhr P, Gregor M et al. High-dose rituximab and anti-MAG-associated polyneuropathy. Neurology66(5), 742–744 (2006).
  • Gorson KC. Clinical features, evaluation, and treatment of patients with polyneuropathy associated with monoclonal gammopathy of undetermined significance (MGUS). J. Clin. Apher.14(3), 149–153 (1999).
  • Dyck PJ, Low PA, Windebank AJ et al. Plasma exchange in polyneuropathy associated with monoclonal gammopathy of undetermined significance. N. Engl. J. Med.325(21), 1482–1486 (1991).
  • Kimby E. Tolerability and safety of rituximab (MabThera). Cancer Treat. Rev.31(6), 456–473 (2005).
  • Plosker GL, Figgitt DP. Rituximab: a review of its use in non-Hodgkin’s lymphoma and chronic lymphocytic leukaemia. Drugs63(8), 803–843 (2003).
  • Reff ME, Carner K, Chambers KS et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood83(2), 435–445 (1994).
  • Rastetter W, Molina A, White CA. Rituximab: expanding role in therapy for lymphomas and autoimmune diseases. Annu. Rev. Med.55, 477–503 (2004).
  • O’Keefe TL, Williams GT, Davies SL, Neuberger MS. Mice carrying a CD20 gene disruption. Immunogenetics48(2), 125–132 (1998).
  • Deans JP, Li H, Polyak MJ. CD20-mediated apoptosis: signalling through lipid rafts. Immunology107(2), 176–182 (2002).
  • Davis TA, White CA, Grillo-Lopez AJ et al. Single-agent monoclonal antibody efficacy in bulky non-Hodgkin’s lymphoma: results of a phase II trial of rituximab. J. Clin. Oncol.17(6), 1851–1857 (1999).
  • Rouziere AS, Kneitz C, Palanichamy A, Dorner T, Tony HP. Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody. Arthritis Res. Ther.7(4), R714–R724 (2005).
  • Pescovitz MD. Rituximab, an anti-CD20 monoclonal antibody: history and mechanism of action. Am. J. Transplant6(5), 859–866 (2006).
  • Gong Q, Ou Q, Ye S et al. Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J. Immunol.174(2), 817–826 (2005).
  • McLaughlin P, Grillo-Lopez AJ, Link BK et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. J. Clin. Oncol.16(8), 2825–2833 (1998).
  • Berinstein NL, Grillo-Lopez AJ, White CA et al. Association of serum rituximab (IDEC-C2B8) concentration and anti-tumor response in the treatment of recurrent low-grade or follicular non-Hodgkin’s lymphoma. Ann. Oncol.9(9), 995–1001 (1998).
  • Ng CM, Bruno R, Combs D, Davies B. Population pharmacokinetics of rituximab (anti-CD20 monoclonal antibody) in rheumatoid arthritis patients during a phase II clinical trial. J. Clin. Pharmacol.45(7), 792–801 (2005).
  • Ruhstaller TW, Amsler U, Cerny T. Rituximab: active treatment of central nervous system involvement by non-Hodgkin’s lymphoma? Ann. Oncol.11(3), 374–375 (2000).
  • Rojas-Garcia R, Gallardo E, de Andres I et al. Chronic neuropathy with IgM anti-ganglioside antibodies: lack of long term response to rituximab. Neurology61(12), 1814–1816 (2003).
  • Broglio L, Lauria G. Worsening after rituximab treatment in anti-MAG neuropathy. Muscle Nerve32(3), 378–379 (2005).
  • Treon SP, Hansen M, Branagan AR et al. Polymorphisms in FcgammaRIIIA (CD16) receptor expression are associated with clinical response to rituximab in Waldenstrom’s macroglobulinemia. J. Clin. Oncol.23(3), 474–481 (2005).
  • Stuve O, Cepok S, Elias B et al. Clinical stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis. Arch. Neurol.62(10), 1620–1623 (2005).
  • Baig S, Jiang YP, Olsson T, Cruz M, Link H. Cells secreting anti-MAG antibody occur in cerebrospinal fluid and bone marrow in patients with polyneuropathy associated with M component. Brain114(Pt 1B), 573–583 (1991).
  • Edwards JC, Szczepanski L, Szechinski J et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N. Engl. J. Med.350(25), 2572–2581 (2004).
  • O’Brien SM, Kantarjian H, Thomas DA et al. Rituximab dose-escalation trial in chronic lymphocytic leukemia. J. Clin. Oncol.19(8), 2165–2170 (2001).
  • Treon SP, Emmanouilides C, Kimby E et al. Extended rituximab therapy in Waldenstrom’s macroglobulinemia. Ann. Oncol.16(1), 132–138 (2005).
  • Lambotte O, Kotb R, Maigne G et al. Efficacy of rituximab in refractory polymyositis. J. Rheumatol.32(7), 1369–1370 (2005).
  • Levine TD. Rituximab in the treatment of dermatomyositis: an open-label pilot study. Arthritis Rheum.52(2), 601–607 (2005).
  • Zaja F, Russo D, Fuga G, Perella G, Baccarani M. Rituximab for myasthenia gravis developing after bone marrow transplant. Neurology55(7), 1062–1063 (2000).
  • Hain B, Jordan K, Deschauer M, Zierz S. Successful treatment of MuSK antibody-positive myasthenia gravis with rituximab. Muscle Nerve33(4), 575–580 (2005).
  • Ruegg SJ, Fuhr P, Steck AJ. Rituximab stabilizes multifocal motor neuropathy increasingly less responsive to IVIg. Neurology63(11), 2178–2179 (2004).
  • Maloney DG, Liles TM, Czerwinski DK et al. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood84(8), 2457–2466 (1994).
  • Higashida J, Wun T, Schmidt S, Naguwa SM, Tuscano JM. Safety and efficacy of rituximab in patients with rheumatoid arthritis refractory to disease modifying antirheumatic drugs and anti-tumor necrosis factor-alpha treatment. J. Rheumatol.32(11), 2109–2115 (2005).
  • Noronha V, Fynan TM, Duffy T. Flare in neuropathy following rituximab therapy for Waldenstrom’s macroglobulinemia. J. Clin. Oncol.24(1), E3 (2006).
  • Eisenberg R, Looney RJ. The therapeutic potential of anti-CD20 “what do B-cells do?” Clin. Immunol.117(3), 207–213 (2005).
  • Suzan F, Ammour M, Ribrag V. Fatal reactivation of cytomegalovirus infection after use of rituximab for a post-transplantation lymphoproliferative disorder. N. Engl. J. Med.345(13), 1000 (2001).
  • Tsutsumi Y, Kanamori H, Mori A et al. Reactivation of hepatitis B virus with rituximab. Expert Opin. Drug Saf.4(3), 599–608 (2005).
  • Foxton MR, Knight L, Knisely AS et al. Liver transplantation for HCV-related cirrhosis in a patient with gastric mucosa-associated lymphoma (MALToma) pretreated with rituximab. Liver Transpl.11(7), 839–842 (2005).
  • Quartuccio L, Soardo G, Romano G et al. Rituximab treatment for glomerulonephritis in HCV-associated mixed cryoglobulinaemia: efficacy and safety in the absence of steroids. Rheumatology (Oxford)45(7), 842–846 (2006).
  • Sansonno D, De Re V, Lauletta G et al. Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon alpha with an anti-CD20. Blood101(10), 3818–3826 (2003).
  • Klepfish A, Schattner A, Shvidel L et al. Successful treatment of aggressive HIV-associated non-Hodgkin’s lymphoma with combination chemotherapy, biotherapy with rituximab and HAART: presentation of a therapeutic option. Leuk. Lymphoma44(2), 349–351 (2003).
  • Leandro MJ, Cambridge G, Edwards JC, Ehrenstein MR, Isenberg DA. B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients. Rheumatology (Oxford)44(12), 1542–1545 (2005).
  • Leonard JP. Targeting CD20 in follicular NHL: novel anti-CD20 therapies, antibody engineering, and the use of radioimmunoconjugates. Hematology Am. Soc. Hematol. Educ. Program335–339 (2005).
  • Vugmeyster Y, Beyer J, Howell K et al. Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis. J. Immunother.28(3), 212–219 (2005).
  • Barohn RJ, Rashid I, McVey AL et al. Rituximab for the treatment of IgM associated polyneuropathies. J. Peripher. Nerv. Syst.10(Suppl. 1), 4 (2005).
  • Weide R, Heymanns J, Koppler H. The polyneuropathy associated with Waldenstrom’s macroglobulinaemia can be treated effectively with chemotherapy and the anti-CD20 monoclonal antibody rituximab. Br. J. Haematol.109(4), 838–841 (2000).
  • Delarue R, Deau B, Alyanakian M-A, Varet BR, Hermin O. Rituximab in anti-MAG associated neuropathy: a monocentric experience. Blood104(11), A4909 (2004).

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