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Drug Profile

Rotigotine for the treatment of Parkinson’s disease

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Pages 1275-1282 | Published online: 10 Jan 2014

References

  • DeStefano AL, Lew MF, Golbe LI et al. PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study. Am. J. Hum. Genet.70(5), 1089–1095 (2002).
  • Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976–1990. Neurology52(6), 1214–1220 (1999).
  • Huse DM, Schulman K, Orsini L et al. Burden of illness in Parkinson’s disease. Mov. Disord.20(11), 1449–1454 (2005).
  • Cotzias GC, Van Woert MH, Schiffer LM. Aromatic amino acids and modification of parkinsonism. N. Engl. J. Med.276(7), 374–379 (1967).
  • Shaunak S, Wilkins A, Pilling JB, Dick DJ. Pericardial, retroperitonel and pleural fibrosis induced by pergolide. J. Neurol. Neurosurg. Psychiatr.66(1), 79–81 (1999).
  • Pritchett AM, Morrison JF, Edwards WD, Schaff HV, Connolly HM, Espinosa RE. Valvular heart disease in patients taking pergolide. Mayo Clin. Proc.77(12), 1280–1286 (2002).
  • Management of Parkinson’s disease: an evidence-based review. Mov. Disord.17(Suppl. 4), S1–S166 (2002).
  • Miyasaki JM, Martin W, Suchowersky O, Weiner WJ, Lang AE. Practice parameter: initiation of treatment for Parkinson’s disease: an evidence-based review: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology58(1), 11–17 (2002).
  • Eisler T, Eng N, Plotkin C, Calne DB. Absorption of levodopa after rectal administration. Neurology31(2), 215–217 (1981).
  • Nausieda PA, Pfeiffer RF, Tagliati M et al. A multicenter, open-label, sequential study comparing preferences for carbidopa–levodopa orally disintegrating tablets and conventional tablets in subjects with Parkinson’s disease. Clin. Ther.27(1), 58–63 (2005).
  • Iyer SS, Morgan JC, Sethi KD. Absorption of orally-disintegrating carbidopa–levodopa requires intact small bowel function. Neurology65(9), 1507 (2005).
  • Clarke A, Brewer F, Johnson ES et al. A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition. J. Neural Transm.110(11), 1241–1255 (2003).
  • Waters CH, Sethi KD, Hauser RA, Molho E, Bertoni JM, Zydis Selegiline Study Group. Zydis selegiline reduces off time in Parkinson’s disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study. Mov. Disord.19(4), 426–432 (2004).
  • Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson’s disease. The Parkinson Study Group. N. Engl. J. Med.328(3), 176–183 (1993).
  • Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: the TEMPO study. Arch. Neurol.59(12), 1937–1943 (2002).
  • Parkinson Study Group. A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations: the PRESTO study. Arch. Neurol.62(2), 241–248 (2005).
  • Rascol O, Brooks DJ, Melamed E et al. Rasagiline as an adjunct to levodopa in patients with Parkinson’s disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial. Lancet365(9463), 947–954 (2005).
  • Beaulieu M, Itoh Y, Tepper P et al. N-disubstituted 2-aminotetralins are potent D-2 dopamine receptor agonists. Eur. J. Pharmacol.105(1–2), 15–21 (1984).
  • Timmerman W, Westerink BH, De Vries JB, Tepper PG, Horn AS. Microdialysis and striatal dopamine release: stereoselective actions of the enantiomers on N-0437. Eur. J. Pharmacol.162(1), 143–150 (1989).
  • Van der Weide J, Tendijck ME, Tepper PF, De Vries JB, Dubocovich ML, Horn AS. The enantiomers of the D-2 dopamine receptor agonist N-0437 discriminate between pre- and post-synaptic dopamine receptors. Eur. J. Pharmacol.146(2–3), 319–326 (1988).
  • Jenner P. A novel dopamine agonist for the transdermal treatment of Parkinson’s disease. Neurology65(2 Suppl. 1), S3–S5 (2005).
  • Belluzzi JD, Domino EF, May JM, Bankiewicz KF, McAfee DA. N-0923, a selective D2 receptor agonist, is efficacious in rat and monkey models of Parkinson’s disease. Mov. Disord.9(2), 147–154 (1994).
  • Mucke HA. Rotigotine Schwarz Pharma. IDrugs6(9), 894–899 (2003).
  • Lebsanft HB, Scheller DKA, Heindl M et al. Effect of continuous administration of rotigotine in a rat model of dyskinesia. Mov. Disord.20(Suppl. 10), S89 (2005).
  • Schneider JC, McLaughlin WW, Roeltgen DP. Anti-Parkinson effects of the selective dopamine D-2 agonist N-0923 in hemi-Parkinsonian monkeys. Neurology42(4 Suppl. 3), 443 (1992).
  • Scheller DK. Neuroprotection by rotigotine: investigations in MPTP-lesioned mice under continuous dopaminergic stimulation. Ann. Neurol.56(Suppl. 8), S54 (2004).
  • Stichel CC, Scheller DKA. Rotigotine prevents neurodegeneration in a mouse model of Parkinson’s disease. 9th Congress of the European Federation of Neurological Societies, Athens, Greece (2005) (Abstract 250).
  • Swart PJ, de Zeeuw RA. Extensive gastrointestinal metabolic conversion limits the oral bioavailability of the dopamine D2 agonist N-0923 in freely moving rats. Pharmazie47(8), 613–615 (1992).
  • Swart PJ, de Zeeuw RA. Pharmacokinetics of the dopamine D2 agonist S(-)-2-(N-propyl-N-2-thienlethylamino)-5-hydroxyteralin in freely moving rats. J. Pharm. Sci.82(2), 200–203 (1993).
  • Calabrese VP, Lloyd KA, Brancazio P et al. N-0923, a novel soluble dopamine D2 agonist in the treatment of parkinsonism. Mov. Disord.13(5), 768–774 (1998).
  • Metman LV, Gillespie M, Farmer C et al. Continuous transdermal dopaminergic stimulation in advanced Parkinson’s disease. Clin. Neuropharmacol.24(3), 163–169 (2001).
  • Güldenpfennig WM, Poole KH, Sommerville KW, Boroojerdi B. Safety, tolerability, and efficacy of continuous transdermal dopaminergic stimulation with rotigotine patch in early-stage idiopathic Parkinson disease. Clin. Neuropharmacol.28(3), 106–110 (2005).
  • Cawello W, Braun M, Horstmann R. Pharmacokinetics of transdermal rotigotine in subjects with impaired renal function. J. Clin. Pharmacol.45(9), 1091(2005) (Abstract 102).
  • Watts RL, Wendt RL, Nausied B et al. Efficacy, safety, and tolerability of the rotigotine transdermal patch in patients with early-stage, idiopathic Parkinson’s disease: a multicenter, multinational, randomized, double-blind, placebo-controlled trial. Mov. Disord.19(Suppl. 9), S258 (2004).
  • Braun M, Cawello W, Poole K et al. Steady-state pharmacokinetics of rotigotine in patients with early-stage Parkinson’s disease. 9th Congress of the European Federation of Neurological Societies, Athens, Greece (2005) (Abstract P1245).
  • Swart PJ, Oelen WE, Bruins AP, Tepper PG, de Zeeuw RA. Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry. J. Anal. Toxicol.18(2), 71–77 (1994).
  • Hansen K, Braun M, Horstmann R. Low drug-drug interaction potential of rotigotine. J. Clin. Pharmacol.45(9), 1091 (2005) (Abstract 101).
  • Braun M, Cawello W, Horstmann R. Lack of pharmacokinetic interaction between the dopamine agonist rotigotine and levodopa/carbidopa. 16th International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany (2005) (Abstract 4775).
  • Hutton JT, Metman LV, Chase TN et al. Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson’s disease with N-0923 TDS: a double-blind, placebo-controlled study. Mov. Disord.16(3), 459–463 (2001).
  • Bianchine J, Poole K, Woltering F. Efficacy and dose response of the novel transdermally applied dopamine agonist rotigotine CDS in early Parkinson’s disease. Neurology58(Suppl. 3), A162–A163 (2002).
  • Parkinson Study Group. A controlled trial of rotigotine monotherapy in early Parkinson’s disease. Arch. Neurol.60(12), 1721–1728 (2003).
  • LeWitt PA, Nausieda PA, Chang F et al. Rotigotine transdermal system as adjunctive therapy to levodopa in patients with advanced-stage Parkinson’s disease. Results of a randomized, double-blind, placebo-controlled, multicenter, multinational trial. 18th World Congress of Neurology Meeting, Sydney, Australia (2005) (Abstract).
  • Quinn N, for the SP511 Investigators. Rotigotine Transdermal Delivery System (TDS) (SP-962): a multi-center, double-blind, randomized, placebo-controlled trial to assess the safety and efficacy of rotigotine TDS in patients with advanced Parkinson’s disease. Parkinsonism Relat. Disord.7(Suppl. 1), S66 (2002).
  • Giladi N, Tolosa E, Boothman B et al. Rotigotine transdermal system in patients with idiopathic Parkinson’s disease: results of two placebo- and comparator controlled trials. Late Breaking Abstract presented at the World Parkinson Congress, Washington, DC, February (2006).
  • Poewe W, Giladi N, Boothman B et al. Rotigotine transdermal system in patients with advanced-stage Parkinson’s disease as adjunctive therapy to levodopa: results of a placebo- and pramipexole-controlled trial. Late Breaking Abstract presented at the World Parkinson Congress, Washington, DC, February (2006).
  • Pfutzner W, Przybilla B. Malignant melanoma and levodopa: is there a relationship? Two new cases and a review of the literature. J. Am. Acad. Dermatol.37(2 Pt 2), 332–333 (1997).
  • Siple JF, Schneider DC, Wanlass WA, Rosenblatt BK. Levodopa therapy and the risk of malignant melanoma. Ann. Pharmacother.34(3), 382–385 (2000).
  • Leopold NA, Polanksy M, Hurka MR. Drug adherence in Parkinson’s disease. Mov. Disord.19(5), 513–517 (2004).
  • Bibbiani F, Constantini LC, Patel R, Chase TN. Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates. Exp. Neurol.192(1), 73–78 (2005).
  • Nutt JG, Obeso JA, Stocchi F. Continuous dopamine-receptor stimulation in advanced Parkinson’s disease. Trends Neurosci.23(Suppl. 10), S109–S115 (2000).
  • Olanow W, Schapira AH, Rascol O. Continuous dopamine-receptor stimulation in early Parkinson’s disease. Trends Neurosci.23(10 Suppl.), S117–S126 (2000).
  • Rascol O, Brooks DJ, Korczyn AD et al. A five-year study of the incidence of dyskinesia in patients with early Parkinson’s disease who were treated with ropinirole or levodopa. 056 Study Group. N. Engl. J. Med.342(20), 1484–1491 (2000).
  • Holloway RG, Shoulson I, Fahn S et al. Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial. Arch. Neurol.61(7), 1044–1053 (2004).
  • Stocchi F, Vacca L, Ruggieri S, Olanow CW. Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: a clinical and pharmacokinetic study. Arch. Neurol.62(6), 905–910 (2005).
  • Lake Y, Pinnock S. Improved patient acceptability with a transdermal drug-in-adhesive oestradiol patch. Aust. NZ J. Obstet. Gynaecol.40(3), 313–316 (2000).
  • Stiasny-Kolster K, Kohnen R, Schollmayer E et al. Patch application of the dopamine agonist rotigotine to patients with moderate to advanced stages of restless legs syndrome: a double-blind, placebo-controlled pilot study. Mov. Disord.19(12), 1432–1438 (2004).
  • Foley P, Gerlach M, Double KL, Riederer P. Dopamine receptor agonists in the therapy of Parkinson’s disease. J. Neural Transm.111(10–11), 1375–1446 (2004).

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