Genetic aspects of cluster headache

References

• Nappi G, Micieli G, Cavallini A, Zanferrari C, Sandrini G, Manzoni GC. Accompanying symptoms of cluster attacks: their relevance to the diagnostic criteria. Cephalalgia12(3), 165–168 (1992).
   PubMed Web of Science ®Google Scholar
• Schurks M, Kurth T, de Jesus J, Jonjic M, Rosskopf D, Diener HC. Cluster headache: clinical presentation, lifestyle features, and medical treatment. Headache46(8), 1246–1254 (2006).
   PubMed Web of Science ®Google Scholar
• Bahra A, May A, Goadsby PJ. Cluster headache: a prospective clinical study with diagnostic implications. Neurology58(3), 354–361 (2002).
   PubMed Web of Science ®Google Scholar
• Ekbom K, Svensson DA, Traff H, Waldenlind E. Age at onset and sex ratio in cluster headache: observations over three decades. Cephalalgia22(2), 94–100 (2002).
   PubMed Web of Science ®Google Scholar
• D’Alessandro R, Gamberini G, Benassi G, Morganti G, Cortelli P, Lugaresi E. Cluster headache in the Republic of San Marino. Cephalalgia6(3), 159–162 (1986).
   PubMed Web of Science ®Google Scholar
• Ekbom K, Ahlborg B, Schele R. Prevalence of migraine and cluster headache in Swedish men of 18. Headache18(1), 9–19 (1978).
   PubMed Web of Science ®Google Scholar
• Sjaastad O, Bakketeig LS. Cluster headache prevalence. Vaga study of headache epidemiology. Cephalalgia23(7), 528–533 (2003).
   PubMed Web of Science ®Google Scholar
• Tonon C, Guttmann S, Volpini M, Naccarato S, Cortelli P, D’Alessandro R. Prevalence and incidence of cluster headache in the Republic of San Marino. Neurology58(9), 1407–1409 (2002).
   PubMed Web of Science ®Google Scholar
• Ekbom K, Svensson DA, Pedersen NL, Waldenlind E. Lifetime prevalence and concordance risk of cluster headache in the Swedish twin population. Neurology67(5), 798–803 (2006).
   PubMed Web of Science ®Google Scholar
• Torelli P, Beghi E, Manzoni GC. Cluster headache prevalence in the Italian general population. Cephalalgia23, 598 (2003).
   Google Scholar
• Torelli P, Beghi E, Manzoni GC. Cluster headache prevalence in the Italian general population. Neurology64(3), 469–474 (2005).
   PubMed Web of Science ®Google Scholar
• Incidence, age at onset, sex and ethnic distribution. In: Cluster Headache Mechanisms and Managements. Kudrow L (Ed.). Oxford University Press, NY, USA 11 (1980).
   Google Scholar
• Black DF, Swanson JW, Stang PE. Decreasing incidence of cluster headache: a population-based study in Olmsted County, Minnesota. Headache45(3), 220–223 (2005).
   PubMedGoogle Scholar
• Waldenlind E, Gustafsson SA, Ekbom K, Wetterberg L. Circadian secretion of cortisol and melatonin in cluster headache during active cluster periods and remission. J. Neurol. Neurosurg. Psychiatr.50(2), 207–213 (1987).
   PubMed Web of Science ®Google Scholar
• Waldenlind E, Gustafsson SA. Prolactin in cluster headache: diurnal secretion, response to thyrotropin-releasing hormone, and relation to sex steroids and gonadotropins. Cephalalgia7(1), 43–54 (1987).
   PubMed Web of Science ®Google Scholar
• Waldenlind E, Ekbom K, Wetterberg L et al. Lowered circannual urinary melatonin concentrations in episodic cluster headache. Cephalalgia14(3), 199–204 (1994).
   PubMed Web of Science ®Google Scholar
• Leone M, Lucini V, D’Amico D et al. Twenty-four-hour melatonin and cortisol plasma levels in relation to timing of cluster headache. Cephalalgia15(3), 224–229 (1995).
   PubMed Web of Science ®Google Scholar
• Leone M, Lucini V, D’Amico D et al. Abnormal 24-hour urinary excretory pattern of 6-sulphatoxymelatonin in both phases of cluster headache. Cephalalgia18(10), 664–667 (1998).
   PubMed Web of Science ®Google Scholar
• Leone M, Bussone G. A review of hormonal findings in cluster headache. Evidence for hypothalamic involvement. Cephalalgia13(5), 309–317 (1993).
   PubMed Web of Science ®Google Scholar
• Waldenlind E, Ross SB, Saaf J, Ekbom K, Wetterberg L. Concentration and uptake of 5-hydroxytryptamine in platelets from cluster headache and migraine patients. Cephalalgia5(1), 45–54 (1985).
   PubMed Web of Science ®Google Scholar
• May A, Bahra A, Buchel C, Frackowiak RS, Goadsby PJ. Hypothalamic activation in cluster headache attacks. Lancet352(9124), 275–278 (1998).
   PubMed Web of Science ®Google Scholar
• May A, Ashburner J, Buchel C et al. Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat. Med.5(7), 836–838 (1999).
   PubMed Web of Science ®Google Scholar
• Goadsby PJ, Edvinsson L. Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute attacks therapies. Brain117(Pt 3), 427–434 (1994).
   PubMed Web of Science ®Google Scholar
• Hardebo JE. How cluster headache is explained as an intracavernous inflammatory process lesioning sympathetic fibers. Headache34(3), 125–131 (1994).
   PubMed Web of Science ®Google Scholar
• Hannerz J. Orbital phlebography and signs of inflammation in episodic and chronic cluster headache. Headache31(8), 540–542 (1991).
   PubMed Web of Science ®Google Scholar
• Martelletti P, Romiti A, Gallo MF et al. HLA-B14 antigen in cluster headache. Headache24(3), 152–154 (1984).
   PubMed Web of Science ®Google Scholar
• Giacovazzo M. New findings in cluster headache. Ann. Ital. Med. Int.5(3 Pt 3), 303–311 (1990).
   PubMedGoogle Scholar
• Giacovazzo M, Martelletti P, Romiti A, Gallo MF, Iuvara E. Relationship between HLA system in cluster headache and clinical response to lithium therapy. Headache25(5), 268–270 (1985).
   PubMed Web of Science ®Google Scholar
• Covelli V, Maffione AB, Ruggeri O et al. Assessment of the immune status in patients with cluster headache. Frequency of immunocompetent cells and analysis of Salmonella spontaneous binding to peripheral blood lymphocytes. Acta Neurol. (Napoli)10(6), 322–330 (1988).
   PubMedGoogle Scholar
• Martelletti P, Giacovazzo M. Putative neuroimmunological mechanisms in cluster headache. An integrated hypothesis. Headache36(5), 312–315 (1996).
   PubMed Web of Science ®Google Scholar
• Martelletti P, Granata M, Giacovazzo M. Serum interleukin-1 β is increased in cluster headache. Cephalalgia13(5), 343–345 (1993).
   PubMed Web of Science ®Google Scholar
• Martelletti P, Stirparo G, De Stefano L, Di Sabato F, Giacovazzo M, Rinaldi-Garaci C. Defective expression of IL-2 receptors on peripheral blood lymphocytes from patients with cluster headache. Headache30(4), 228–231 (1990).
   PubMed Web of Science ®Google Scholar
• Sjostrand C, Duvefelt K, Steinberg A, Remahl IN, Waldenlind E, Hillert J. Gene expression profiling in cluster headache: a pilot microarray study. Headache46(10), 1518–1534 (2006).
   PubMed Web of Science ®Google Scholar
• Olesen J, Thomsen LL, Iversen H. Nitric oxide is a key molecule in migraine and other vascular headaches. Trends Pharmacol. Sci.15(5), 149–153 (1994).
   PubMed Web of Science ®Google Scholar
• Martelletti M, Stirparo G, Giacovazzo M. Nitric oxide synthase activation in cluster headache florid phase. In: Cluster Headache and Related Conditions. Olesen J, Goadsby P (Eds). Oxford University Press, Oxford, UK 135–139 (1999).
   Google Scholar
• El Amrani M, Ducros A, Boulan P et al. Familial cluster headache: a series of 186 index patients. Headache42(10), 974–977 (2002).
   PubMed Web of Science ®Google Scholar
• Kudrow L, Kudrow DB. Inheritance of cluster headache and its possible link to migraine. Headache34(7), 400–407 (1994).
   PubMed Web of Science ®Google Scholar
• Russell MB, Andersson PG, Thomsen LL. Familial occurrence of cluster headache. J. Neurol. Neurosurg. Psychiatr.58(3), 341–343 (1995).
   PubMed Web of Science ®Google Scholar
• Leone M, Russell MB, Rigamonti A et al. Increased familial risk of cluster headache. Neurology56(9), 1233–1236 (2001).
   PubMed Web of Science ®Google Scholar
• Russell MB. Epidemiology and genetics of cluster headache. Lancet Neurol.3(5), 279–283 (2004).
   PubMed Web of Science ®Google Scholar
• Russell MB, Andersson PG, Thomsen LL, Iselius L. Cluster headache is an autosomal dominantly inherited disorder in some families: a complex segregation analysis. J. Med. Genet.32(12), 954–956 (1995).
   PubMed Web of Science ®Google Scholar
• Eadie MJ Sutherland JM. Migrainous neuralgia. Med. J. Aust.1, 1053–1057 (1966).
   PubMedGoogle Scholar
• Couturier EG, Hering R, Steiner TJ. The first report of cluster headache in identical twins [see comments]. Neurology41(5), 761 (1991).
   PubMed Web of Science ®Google Scholar
• Roberge C, Bouchard JP, Simard D, Gagne R. Cluster headache in twins [letter; comment]. Neurology42(6), 1255–1256 (1992).
   PubMedGoogle Scholar
• Sjaastad O, Shen JM, Stovner LJ, Elsas T. Cluster headache in identical twins. Headache33(4), 214–217 (1993).
   PubMed Web of Science ®Google Scholar
• Sjaastad O, Salvesen R. Cluster headache: are we only seeing the tip of the iceberg? Cephalalgia6(3), 127–129 (1986).
   PubMed Web of Science ®Google Scholar
• Lampl C. Left-sided migraine headache interrupted by periods of right-sided cluster headaches in identical twins – another puzzle for modular headache theory. Cephalalgia22, 583 (2002).
   Google Scholar
• Motulsky AG. Biased ascertainment and the natural history of diseases. N. Engl. J. Med.298, 1196–1197 (1978).
   PubMed Web of Science ®Google Scholar
• Svensson D, Ekbom K, Pedersen NL, Traff H, Waldenlind E. A note on cluster headache in a population-based twin register. Cephalalgia23(5), 376–380 (2003).
   PubMed Web of Science ®Google Scholar
• Russell MB, Andersson PG. Clinical intra- and interfamilial variability of cluster headache. Eur. J. Neurol.1, 253–257 (1995).
   PubMedGoogle Scholar
• Manzoni GC. Cluster headache and lifestyle: remarks on a population of 374 male patients. Cephalalgia19(2), 88–94 (1999).
   PubMed Web of Science ®Google Scholar
• Levi R, Edman GV, Ekbom K, Waldenlind E. Episodic cluster headache. II: High tobacco and alcohol consumption in males. Headache32(4), 184–187 (1992).
   PubMed Web of Science ®Google Scholar
• Graham JR, Rogado AZ, Rahman M, Gramer IV. Some physical, physiological and psychological characteristics of patients with cluster headache. In: Background to Migraine. Cochrane AL (Ed.). Heinemann, London, UK 38–51 (1970).
   Google Scholar
• Rozen TD. Childhood exposure to second-hand tobacco smoke and the development of cluster headache. Headache45(4), 393–394 (2005).
   PubMedGoogle Scholar
• Headache Classification Committee of the International Headache Society. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalalgia8(Suppl. 7), 1–96 (1988).
   Web of Science ®Google Scholar
• Torelli P, Manzoni GC. Clinical observations on familial cluster headache. Neurol. Sci.24(2), 61–64 (2003).
   PubMed Web of Science ®Google Scholar
• Leone M, Rigamonti A, Bussone G. Cluster headache sine headache: two new cases in one family. Cephalalgia22(1), 12–14 (2002).
   PubMed Web of Science ®Google Scholar
• van Vliet JA, Ferrari MD, Haan J. Genetic factors in cluster headache. Expert Rev. Neurother.3(3), 301–306 (2003).
   PubMedGoogle Scholar
• The International Classification of Headache Disorders. Cephalalgia24(Suppl. 1), 1–160 (2004).
   Web of Science ®Google Scholar
• Sjostrand C, Russell MB, Ekbom K, Hillert J, Waldenlind E. Familial cluster headache. Is atypical cluster headache in family members part of the clinical spectrum? Cephalalgia25(11), 1068–1077 (2005).
   PubMed Web of Science ®Google Scholar
• Sjaastad O, de Souza Carvalho D, Zhao JM. “Mild”cluster headache(?). Cephalalgia8(2), 121–126 (1988).
   PubMed Web of Science ®Google Scholar
• Martins IP, Gouveia RG, Parreira E. Cluster headache without autonomic symptoms: why is it different? Headache45(3), 190–195 (2005).
   PubMedGoogle Scholar
• Shimomura T, Kitano A, Marukawa H et al. Point mutation in platelet mitochondrial tRNA(Leu(UUR)) in patient with cluster headache. Lancet344(8922), 625 (1994).
   PubMed Web of Science ®Google Scholar
• Seibel P, Grunewald T, Gundolla A, Diener HC, Reichmann H. Investigation on the mitochondrial transfer RNA(Leu)(UUR) in blood cells from patients with cluster headache. J. Neurol.243(4), 305–307 (1996).
   PubMed Web of Science ®Google Scholar
• Cortelli P, Zacchini A, Barboni P, Malpassi P, Carelli V, Montagna P. Lack of association between mitochondrial tRNA(Leu(UUR)) point mutation and cluster headache. Lancet345(8957), 1120–1121 (1995).
   PubMed Web of Science ®Google Scholar
• Odawara M, Tamaoka A, Mizusawa H, Yamashita K. A case of cluster headache associated with mitochondrial DNA deletions. Muscle Nerve20(3), 394–395 (1997).
   PubMed Web of Science ®Google Scholar
• Ophoff RA, Terwindt GM, Vergouwe MN et al. Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell87(3), 543–552 (1996).
   PubMed Web of Science ®Google Scholar
• Sjostrand C, Giedratis V, Ekbom K, Waldenlind E, Hillert J. CACNA1A gene polymorphisms in cluster headache. Cephalalgia21(10), 953–958 (2001).
   PubMed Web of Science ®Google Scholar
• Haan J, van Vliet JA, Kors EE et al. No involvement of the calcium channel gene (CACNA1A) in a family with cluster headache. Cephalalgia21(10), 959–962 (2001).
   PubMed Web of Science ®Google Scholar
• Sjostrand C, Modin H, Masterman T, Ekbom K, Waldenlind E, Hillert J. Analysis of nitric oxide synthase genes in cluster headache. Cephalalgia22(9), 758–764 (2002).
   PubMed Web of Science ®Google Scholar
• Aridon P, D’Andrea G, Rigamonti A, Leone M, Casari G, Bussone G. Elusive amines and cluster headache: mutational analysis of trace amine receptor cluster on chromosome 6q23. Neurol Sci, 25(Suppl. 3), S279–S280 (2004).
   Google Scholar
• Rainero I, Rivoiro C, Rubino E et al. Prevalence of HFE (hemochromatosis) gene mutations in patients with cluster headache. Headache45(9), 1219–1223 (2005).
   PubMed Web of Science ®Google Scholar
• Peyron C, Faraco J, Rogers W et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat. Med.6(9), 991–997 (2000).
   PubMed Web of Science ®Google Scholar
• Rainero I, Gallone S, Valfre W et al. A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache. Neurology63(7), 1286–1288 (2004).
   PubMed Web of Science ®Google Scholar
• Rainero I, Rivoiro C, Gallone S et al. Lack of association between the 3092 T-->C Clock gene polymorphism and cluster headache. Cephalalgia25(11), 1078–1081 (2005).
   PubMed Web of Science ®Google Scholar
• Cevoli S, Mochi M, Pierangeli G et al. Investigation of the T3111C CLOCK gene polymorphism in cluster headache. J. Neurol.255(2), 299–300 (2008).
   PubMed Web of Science ®Google Scholar
• Schurks M, Kurth T, Stude P et al. G protein β3 polymorphism and triptan response in cluster headache. Clin. Pharmacol. Ther.82(4), 396–401 (2007).
   PubMed Web of Science ®Google Scholar
• Baumber L, Sjostrand C, Leone M et al. A genome-wide scan and HCRTR2 candidate gene analysis in a European cluster headache cohort. Neurology66(12), 1888–1893 (2006).
   PubMed Web of Science ®Google Scholar
• Schurks M, Kurth T, Geissler I, Tessmann G, Diener HC, Rosskopf D. Cluster headache is associated with the G1246A polymorphism in the hypocretin receptor 2 gene. Neurology66(12), 1917–1919 (2006).
   PubMed Web of Science ®Google Scholar
• Schurks M, Kurth T, Geissler I, Tessmann G, Diener HC, Rosskopf D. The G1246A polymorphism in the hypocretin receptor 2 gene is not associated with treatment response in cluster headache. Cephalalgia27(4), 363–367 (2007).
   PubMed Web of Science ®Google Scholar
• Rainero I, Rubino E, Valfrè W et al. Association between the G1246A polymorphism of the hypocretin receptor 2 gene and cluster headache: a meta-analysis. J. Headache Pain8(3), 152–156 (2007).
   PubMed Web of Science ®Google Scholar
• Rainero I, Gallone S, Rubino E et al. Haplotype analysis confirms the association between the HCRTR2 gene and cluster headache. Headache48(7), 1108–1114 (2008).
   PubMed Web of Science ®Google Scholar