Blood glucose in acute stroke

References

• Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke32, 2426–2432 (2001).
   PubMed Web of Science ®Google Scholar
• Moustafa RR, Baron J-C. Pathophysiology of ischaemic stroke: insights from imaging, and implications for therapy and drug discovery. Br. J. Pharmacol.153, S44–S54 (2008).
   Google Scholar
• Jørgensen HS, Sperling B, Nakayama H, Raaschou Olsen TS. Spontaneous reperfusion of cerebral infarcts in acute stroke patients. Incidence, time course and clinical outcome: the Copenhagen Stroke Study. Arch. Neurol.51, 865–873 (1994).
   PubMed Web of Science ®Google Scholar
• Neumann-Haefelin T, du Mesnil de Rochemont R, Fiebach JB et al. Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusiona magnetic resonance imaging study. Stroke35(1), 109–115 (2004).
   PubMed Web of Science ®Google Scholar
• Bowler JV, Wade JPH, Jones BE, Nijran KS, Steiner TJ. HMPAO SPECT human cerebral infarcts as assessed by 99mTc. J. Neurol. Neurosurg. Psychiatry64, 90–97 (1998).
   PubMed Web of Science ®Google Scholar
• Aur RN, Siesjö B. Biological differences between ischemia, hypoglycemia and epilepsy. Ann. Neurol.24, 699–707 (1988).
   PubMed Web of Science ®Google Scholar
• Pulsinelli WA, Waldman S, Rawlinson D, Plum F. Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat. Neurology32, 1239–1246 (1982).
   PubMed Web of Science ®Google Scholar
• Rehncrona S, Rosen I, Siesjo BK. Brain lactic acidosis and ischemic cell damage: 1. Biochemistry and neurophysiology. J. Cereb. Blood Flow Metab.1, 297–311 (1981).
   PubMed Web of Science ®Google Scholar
• Kawai N, Keep RF, Betz AL. Effects of hyperglycemia on cerebral blood flow and edema formation after carotid artery occlusion in Fischer 344 rats. Acta Neurochir.70(Suppl. 2), 34–36 (1997).
   Google Scholar
• Dietrich WD, Alonso O, Busto R. Moderate hyperglycemia worsens acute blood–brain barrier injury after forebrain ischemia in rats. Stroke24, 111–116 (1993).
   PubMed Web of Science ®Google Scholar
• de Courten-Myers GM, Kleinholz M, Holm P, Schmitt G, Wagner KR, Myers RE. Hemorrhagic infarct conversion in experimental stroke. Ann. Emerg. Med.21, 120–125 (1992).
   PubMed Web of Science ®Google Scholar
• Vriensendorp TM, DeVries JH, Hoekstra JBL. Hypoglycemia and strict glycemic control in critically ill patients. Curr. Opin. Crit. Care14, 397–402 (2008).
   PubMed Web of Science ®Google Scholar
• de Courten–Myers GM, Kleinholz M, Wagner KR, Myers RE. Fatal strokes in hyperglycemic cats. Stroke20, 1707–1715 (1989).
   PubMed Web of Science ®Google Scholar
• Prado R, Ginsberg MD, Dietrich WD, Watson BD, Busto R. Hyperglycemia increases infarct size in collaterally perfused but not end-arterial vascular territories. J. Cereb. Blood Flow Metab.8, 186–192 (1988).
   PubMed Web of Science ®Google Scholar
• Kawai N, Keep RF, Betz AL. Hyperglycemia and the vascular effects of cerebral ischemia. Stroke28, 149–154 (1997).
   PubMed Web of Science ®Google Scholar
• Ginsberg MD, Prado R, Dietrich WD, Busto R, Watson BD. Hyperglycemia reduces the extent of cerebral infarction in rats. Stroke18, 570–574 (1987).
   PubMed Web of Science ®Google Scholar
• Nedergaard M, Gjedde A, Diemer NH. Hyperglycemia protects against neuronal injury around experimental brain infarcts. Neurol. Res.9, 241–244 (1987).
   PubMedGoogle Scholar
• Zasslow MA, Pearl RG, Shuer LM, Steinberg GK, Lieberson RE, Larson CPJ. Hyperglycemia decreases acute neuronal ischemic changes after middle cerebral artery occlusion in cats. Stroke20, 519–523 (1989).
   PubMed Web of Science ®Google Scholar
• Kraft SA, Larson CPJ, Shuer LM, Steinberg GK, Benson GV, Pearl RG. Effect of hyperglycemia on neuronal changes in a rabbit model of focal cerebral ischemia. Stroke21, 447–450 (1990).
   PubMed Web of Science ®Google Scholar
• Combs DJ, Dempsey RJ, Kumar S, Donaldson D. Focal cerebral infarction in cats in the presence of hyperglycemia and increased insulin. Metab. Brain Dis.5, 169–178 (1990).
   PubMed Web of Science ®Google Scholar
• Voll C, Auer R. The effect of postischemic blood glucose levels on ischemic brain damage in the rat. Ann. Neurol.24, 638–646 (1988).
   PubMed Web of Science ®Google Scholar
• Parsons MW, Barber PA, Desmond PM et al. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study. Ann. Neurol.52, 20–28 (2002).
   PubMed Web of Science ®Google Scholar
• Baird TA, Parsons MW, Phanh T et al. Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome. Stroke34, 2208–2214 (2003).
   PubMed Web of Science ®Google Scholar
• Alvarez-Sabin J, Molina CA, Montaner J et al. Effects of admission hyperglycemia on strokeoutcome in reperfused tissue plasminogen activator-treated patients. Stroke34, 1235–1241 (2003).
   PubMed Web of Science ®Google Scholar
• Williams LS, Rotich J, Qi R et al. Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke. Neurology59, 67–71 (2002).
   PubMed Web of Science ®Google Scholar
• Yong M, Kaste M. Dynamic of Hyperglycemia as a predictor of stroke outcome in the ECASS-II trial. Stroke39, 2749–2755 (2008).
   PubMed Web of Science ®Google Scholar
• Allport LE, Baird TA, Butcher KS et al. Frequency and temporal profile of poststroke hyperglycemia using continuous glucose monitoring. Diabetes Care29, 1839–1844 (2006).
   PubMed Web of Science ®Google Scholar
• Bruno A, Levine SR, Frankel MR et al. Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology59, 669–674 (2002).
   PubMed Web of Science ®Google Scholar
• Jørgensen HS, Nakayama H, Raaschou HO, Olsen TS. Stroke in patients with diabetes: the Copenhagen Stroke Study. Stroke25, 1977–1984 (1994).
   PubMed Web of Science ®Google Scholar
• Gray C, Hildreth A, Sandercock P et al.; for the GIST Trialists Collaboration. Glucose–potassium–insulin infusions in the management of post stroke hyperglycaemia. The United Kingdom Glucose Insulin in Stroke Trial (GIST-UK): a randomised controlled trial. Lancet Neurol.6, 397–406 (2007).
   PubMed Web of Science ®Google Scholar
• Walters MR, Weir CJ, Lees K. A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hyperglycaemic acute ischemic stroke patients. Cerebrovasc. Dis.22, 116–122 (2006).
   PubMed Web of Science ®Google Scholar
• Christensen H, Boysen G. Blood glucose increases early after stroke onset: a study on serial measurements of blood glucose in acute stroke. Eur. J. Neurol.9, 297–301 (2002).
   PubMed Web of Science ®Google Scholar
• Wong AA, Schluter PJ, Henderson RD, O’Sullivan JD, Read SJ. Natural history of blood glucose within the first 48 hours after ischemic stroke. Neurology70, 1036–1041 (2008).
   PubMed Web of Science ®Google Scholar
• Stead LG, Rachel GM. Gilmore RM et al. Hyperglycemia as an independent predictor of worse outcome in non-diabetic patients presenting with acute ischemic stroke. Neurocrit. Care DOI: 10.1007/s12028-008-9080-9080 (2008) (Epub ahead of print).
   Google Scholar
• Scott JF, Robinson GM, French JM et al. Prevalence of admission hyperglycemia across clinical subtypes of acute stroke. Lancet353, 376–377 (1999).
   PubMed Web of Science ®Google Scholar
• Passero S, Ciacci G, Ulivelli M. The influence of diabetes and hyperglycemia on clinical course after intracerebral hemorrhage. Neurology61, 1351–1356 (2003).
   PubMed Web of Science ®Google Scholar
• Franke CL, van Swieten JC, Algra A, van Gijn J. Prognostic factors in patients with intracerebral hematoma. J. Neurol. Neurosurg. Psychiatry55, 653–657 (1992).
   PubMed Web of Science ®Google Scholar
• Fogelholm R, Murros K, Rissanen A, Avikainen S. Admission blood glucose and short term survival in primary intracerebral hemorrhage: a population based study. J. Neurol. Neurosurg. Psychiatry76, 349–353 (2005).
   PubMed Web of Science ®Google Scholar
• Kimura K, Iguchi Y, Inoue T et al. Hyperglycemia independently increases the risk of early death in acute spontaneous intracerebral hemorrhage. J. Neurol. Sci.255, 90–94 (2007).
   PubMed Web of Science ®Google Scholar
• Weir CJ, Murray GD, Dyker AG, Lees KR. Is hyperglycemia an independent predictor of poor outcome after stroke? Results of a long term follow up study. BMJ314, 1303–1306 (1997).
   PubMed Web of Science ®Google Scholar
• Bruno A, Biller J, Adams HP Jr et al. Acute blood glucose level and outcome from ischemic stroke. Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. Neurology52, 280–284 (1999).
   PubMed Web of Science ®Google Scholar
• van Kooten F, Hoogerbrugge N, Naarding P, Koudstaal PJ. Hyperglycemia in the acute phase of stroke is not caused by stress. Stroke24, 1129–1132 (1993).
   PubMed Web of Science ®Google Scholar
• Candelise L, Landi G, Orazio EN, Boccardi E. Prognostic significance of hyperglycemia in acute stroke. Arch. Neurol.42, 661–663 (1985).
   PubMedGoogle Scholar
• O’Neill PA, Davies I, Fullerton KJ, Bennett D. Stress hormone and blood glucose response following acute stroke in the elderly. Stroke22, 842–847 (1991).
   PubMed Web of Science ®Google Scholar
• Tracey F, Crawford VL, Lawson JT, Buchanan KD, Stout RW. Hyperglycaemia and mortality from acute stroke. Q J Med.86, 439–446 (1993).
   PubMedGoogle Scholar
• Murros K, Fogelholm R, Kettunen S, Vuorela AL. Serum cortisol and outcome of ischemic brain infarction. J. Neurol. Sci.116, 12–17 (1993).
   PubMed Web of Science ®Google Scholar
• The NINDS rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med.333, 1581–1587 (1995).
   PubMed Web of Science ®Google Scholar
• Els T, Klisch J, Orszagh M et al. Hyperglycemia in patients with focal cerebral ischemia after intravenous thrombolysis: influence on clinical outcome and infarct size. Cerebrovasc. Dis.13, 89–94 (2002).
   PubMed Web of Science ®Google Scholar
• Ribo M, Molina CA, Delgado P et al. Hyperglycaemia during ischaemia rapidly accelerates brain damage in stroke patients treated with tPa. J. Cereb. Blood Flow Metabol.27, 1616–1622 (2007).
   PubMed Web of Science ®Google Scholar
• Ribo M, Molina C, Montaner J et al. Acute hyperglycemia state is associated with lower tPA-induced recanalization rates in stroke patients. Stroke36, 1705–1709 (2005).
   PubMed Web of Science ®Google Scholar
• Wahlgren N, Ahmed N, Davalos A et al. Thrombolysis with alteplase for acute ischaemic stroke in Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet369, 275–282 (2007).
   PubMed Web of Science ®Google Scholar
• Lansberg MG, Albers GW, Wijman CAC. Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Cerebrovasc. Dis.24, 1–10 (2007).
   PubMed Web of Science ®Google Scholar
• Van den Berghe G, Wouters PJ, Weekers F et al. Intensive insulin therapy in critically ill patients. N. Engl. J. Med.345, 1359–1367 (2001).
   PubMed Web of Science ®Google Scholar
• Malmberg K, Ryden L, Efendic S et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J. Am. Coll. Cardiol.26, 57–65 (1995).
   PubMed Web of Science ®Google Scholar
• Pittas AG, Siegel RD, Lau J. Insulin therapy and in-hospital mortality in critically ill patients: systematic review and meta-analysis of randomized controlled trials. J. Parenter. Enteral Nutr.30, 164–172 (2006).
   PubMed Web of Science ®Google Scholar
• Malmberg K, Rydén L, Wedel H et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur. Heart J.26, 650–661 (2005).
   PubMed Web of Science ®Google Scholar
• The Action to Control Cardiovasular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J. Med.358, 2545–2549 (2008).
   PubMed Web of Science ®Google Scholar
• Van den Berghe G, Wilmer A, Hermans G et al. Intensive insulin therapy in the medical ICU. N. Engl. J. Med.354, 449–461 (2006).
   PubMed Web of Science ®Google Scholar
• The CREATE-ECLA Trial Group Investigators. Effect of glucose–insulin–potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction. JAMA293, 437–446 (2005).
   PubMed Web of Science ®Google Scholar
• Devos P, Preiser JC, Melot C; for the Glucontrol Steering Committee: Impact of tight glucose control by intensive insulin therapy on ICU mortality and the rate of hypoglycaemia: final results of the Glucontrol study. Intensive Care Med.33, S189 (2007).
   Google Scholar
• Brunkhorst FM, Engel C, Bloos F et al. Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis. N. Engl. J. Med.358, 125–139 (2008).
   PubMed Web of Science ®Google Scholar
• Treggiari MM, Karir V, Yanez ND, Weiss NS, Daniel S, Deem SA. Intensive insulin therapy and mortality in critically ill patients. Crit. Care12(1), R29 (2008).
   PubMed Web of Science ®Google Scholar
• Wiener RS, Wiener DC, Larson RJ. Benefits and risks of tight glucose control in critically ill adults. A metaanalysis. JAMA300, 933–944 (2008).
   PubMed Web of Science ®Google Scholar
• Braatvedt GD. Glucose control peri-myocardial infarction. Int. Med. J.38, 341–344 (2008).
   Google Scholar
• Gandhi GY, Nuttall GA, Abel MD et al. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery. Ann. Intern. Med.146, 233–243 (2007).
   PubMed Web of Science ®Google Scholar
• Finfer S, Delaney A. Tight glycemic control in critically ill adults. JAMA300, 963–965 (2008).
   PubMed Web of Science ®Google Scholar
• Hacke W, Kaste M, Fieschi C et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators. Lancet352, 1245–1251 (1998).
   PubMed Web of Science ®Google Scholar
• Walters MR, Weir CJ, Lees KR. A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hyperglycaemic acute stroke patients. Cerebrovasc. Dis.22, 116–122 (2006).
   PubMed Web of Science ®Google Scholar
• Bruno A, Kent T, Coull BM et al. Treatment of hyperglycemia in ischemic stroke (THIS). A randomized pilot trial. Stroke39, 384–389 (2008).
   PubMed Web of Science ®Google Scholar
• Adams HP Jr, del Zoppo G, Alberts MJ et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups. Stroke38, 1655–1711 (2007).
   PubMed Web of Science ®Google Scholar
• Gray CS, Hildreth AJ, Alberti GKMM, O’Connell JE. Poststroke hyperglycemia natural history and immediate management. Stroke35, 122–126 (2004).
   PubMed Web of Science ®Google Scholar