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Editorial

Is it over for ezetimibe?

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Pages 781-783 | Published online: 10 Jan 2014

References

  • Kastelein JJP, Akdim F, Stroes ESG et al. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N. Engl. J. Med.358, 1431–1443 (2008).
  • Smilde TJ, van Wissen S, Awollersheim H, Trip MD, Kastelein JJP, Stalenhoef AFH. Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolemia (ASAP): a prospective, randomised, double-blind trial. Lancet357, 577–581 (2001).
  • Johnson HM, Douglas PS, Srinivasan SR et al. Predictors of carotid intima-media thickness progression in young adults: the Bogalusa Heart Study. Stroke38, 900–905 (2007).
  • Underhill HR, Yuan C, Zhao X-Q et al. Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am. Heart J.155, 584.e581–584.e588 (2008).
  • van Wissen S, Smilde TJ, Trip MD, Stalenhoef AFH, Kastelein JJP. Long-term safety and efficacy of high-dose atorvastatin treatment in patients with familial hypercholesterolemia. Am. J. Cardiol.95, 264–266 (2005).
  • Robinson J, Davidson M. Combination therapy with ezetimibe and simvastatin to acheive aggressive LDL reduction. Expert Rev. Cardiovasc. Ther.4(5), 461–476 (2006).
  • Robinson JG, Smith B, Maheshwari N, Schrott H. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J. Am. Coll. Cardiol.46, 1855–1862 (2005).
  • Brown BG, Taylor AJ. Does ENHANCE diminish confidence in lowering LDL or in ezetimibe? N. Engl. J. Med.358, 1504–1507 (2008).
  • Wong J, Quinn CM, Gelissen IC, Jessup W, Brown AJ. The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation. Atherosclerosis196, 180–189 (2008).
  • Drazen JM, Jarcho JA, Morrissey S, Curfman GD. Cholesterol lowering and ezetimibe. N. Engl. J. Med.358, 1507–1508 (2008).
  • Davidson M, Robinson JG. Safety of aggressive lipid management. J. Am. Coll. Cardiol.49, 1753–1762 (2007).
  • Cholesterol Treatment Trialists’ (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet366, 1267–1278 (2005).

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