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Drug Evaluation

Lamivudine for chronic hepatitis B

Pages 173-180 | Published online: 10 Jan 2014

References

  • Lai CL, Chien RN, Leung NWY, et al A 1 year trial of lamivudine for chronic hepatitis Br N Engl j Meal 339,61–68 (1998).
  • Dienstag JL, Schiff ER, Wright TL, et al Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J. Med 341(17), 1256–1263 (1999).
  • Tassopoulos NC, Volepes R, Pastores G, et al Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Mutant Study Group. Hepatology 29(3), 889–896 (1999).
  • Schalm SW, Heathcote J, Cianciara J, et al. Lamivudine and interferon-a combination treatment of patients with chronic hepatitis B infection, a randomized trial. Gut 46,562–568 (2000).
  • Jarvis B, Faulds D. Lamivudine — a review of its therapeutic potential in chronic hepatitis B. Drugs 58(1), 101–104 (1999).
  • Liaw YF, Leung NWY, Chang TT, et al. Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B.Gastroenterology 119, 172–180 (2000).
  • Lim SG, Wai CT, Rajnakova A, Kajiji T, Guan R. Fatal hepatitis B reactivation following discontinuation of nucleoside analogues for chronic hepatitis B. Gut 51(4), 597–599 (2002).
  • Chien RN, Liaw YF, Atkins M. Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Asian Hepatitis Lamivudine Trial Group. Hepatology 30(3), 770–774 (1999).
  • Perillo RP, Lai CL, Liaw YF, et al. Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B. Hepatology 36(10), 186–194 (2002).
  • Guan R, Lai CL, Liaw YF, et al Efficacy and safety of 5 years lamivudine treatment of Chinese patients with chronic hepatitis. Gastroenterol Hepatol 16(Suppl.) 187(2001)
  • Lok AS, Heathcote EJ, Hoofnagle JH. Management of hepatitis B, 2000— summary of a workshop. Gastroenterology 120, 1828–1853 (2001).
  • Liaw YF, Leung N, Guan R, Lau GKK, Merican I. Asia—Pacific consensus statement on the management of chronic hepatitis B, an update. J. Gastroenterol Hepatol 18(3), 239–245 (2003).
  • Proceedings of the European Association for the Study of the Liver (EASL) International Consensus Conference on Hepatitis B. Geneva, Switzerland, 14–16 September 2002.j Heptol 39\(Suppl. 1) S1—S235 (2003).
  • Allen MI, Gauthier J, Des Lauriers M, et al. Two sensitive PCR-based methods for the detection of virus variants associated with reduced susceptibility to lamivudine. J. Clin. Microbial 37,3338–3347 (1999).
  • Stuyver LJ, Lorcarnini SA, Lok A, et al. Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region. Hepatology 33(3), 751–757 (2001).
  • Liaw YF, Chien RN, Yeh CT, Tsai SL, Chu CM. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 30(2), 567–572 (1999).
  • ••Clinical course of patients with lamivudineresistant mutants.
  • Lok A, Lai CL, Leung N, et al. Long term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 125(6), 1417–1422 (2003).
  • Lai CL, Dienstag J, Schiff E, et al Prevalence and clinical corelates of YMDD variants during lamivudine therapy for patients with chronic hepatitis. Br. Clin. Infect. Dis. 36(6), 687–689 (2003).
  • Wong VW, Chan HLY, Leung NW Clinical course after stopping lamivudine in chronic hepatitis B patients with lamivudine-resistant mutant. Aliment. Pharmacol Ther. 19(3), 323–329 (2004).
  • Perrillo R, Hann HWL, Mutimer D, et al Adefovir dipivoxil added to maintenance lamivudine in chronic hepatitis B with YMDD mutants HBV and a reduced response to lamivudine. Gastroenterology 126(1), 81-90(2004)
  • Leung NWY, Lai CL, Chang TT, et al. and the Asia Hepatitis Lamivudine Study Group. Extended lamivudine treatment in patients with chronic hepatitis B enhances heaptitis e antigen seroconversion rates, results after 3 years of therapy. Hepatology 33(6), 1527–1532 (2001).
  • ••Results from 3 years of lamivudine therapy among Asian patients, demonstrating histologic deterioration among patients with lamivudine resistant mutants.
  • Dienstag JL, Goldin RD, Heathecoate EJ, et al. Histological outcome during long term lamividine therapy. Gastroenterology 124(1), 105–117 (2003).
  • Histologic outcome among patients from international trials showed improvement among patients with maintained virologic response but deterioration when viral breakthrough occurs.
  • ••23Leung NWY, Lai CL, Guan R, Liaw Y-F. The effect of longer duration of harbouring lamivudine-resistant hepatitis B virus (YMDD mutants) on liver histology during 3 years lamivudine therapy in Chinese patients. Hepatology 34(4), 348A (2001) (Abstract 706).
  • Leung NW, Liaw Y-F, Chang T-T, et al. Durable HBeAg response in Chinese patients treated with lamivudine. Hepatology 34(4), 348A (2001) (Abstract 705).
  • Dienstag JL, Cianciara J, Karayalcin S, et al. Durabililty of serology after lamivudine treatment of chronic hepatitis B. Hepatology 37(4), 748–755 (2003).
  • Song B-C, Suh DJ, Lee HC, Chung Y-H, Lee YS. Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea. Hepatology 32, 803–806 (2000).
  • Ryu SH, Chung YH, Choi MH, et al. Long term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss, a prospective study. J. Hepatol. 39(4), 614–619 (2003).
  • Van Nunen AB, Hansen BE, Suh DJ, et al. Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B, relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase. Gut 52(3), 420–424 (2003).
  • Chien R-N, Yeh C-T, Tsai S-L, Chu C-M, Liaw Y-F. Determinants for sustained HBeAg response to lamivudine therapy. Hepatology 38,1267–1273 (2003).
  • Chien RN, Lin CH, Liaw YF. The effect of lamivudine therapy in hepatic decompensation during acute exacerbation of chronic hepatitis B. Hepatology 38(3), 322–327 (2003).
  • •Role of lamivudine therapy in hepatic decompensation during acute exacerbation, the importance of early therapy.
  • Chan HL, Tsang SW, Hui Y, Leung NW, Chan FK, Sung JJ. The role of lamivudine and predictors of mortality in severe flare-up of chronic hepatitis B with jaundice. J. Viral. Hepat. 9(6), 424–428 (2002).
  • Villeneuve J-P, Condreay LD, Willems B, et al Lamivudine treatment for decompensated cirrhosis resulting from chronic hepatitis B. Hepatology 31, 207-210(2000).
  • Liaw YF, Sung JY, Chow WC, Shue K, Keene O, Farrell G. Effect of lamivudine on disease progression and development of liver cancer in advanced chronic hepatitis B. A prospective double-blind placebo-controlled clinical trial. Hepatology 38(4) (Suppl. 1), 262A (2003).
  • •Benefit of long term lamivudine therapy among viremic patients with cirrhosis.
  • Perillo RP, Wright T, Rakela J, et al. and the Lamivudine North American Transplant Group. A multicenter United States—Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B. Hepatology 33,424–432 (2001).
  • Nery JR, Nery-Avila C, Reddy KR, et al. Use of grafts from donors positive for antihepatitis B-core antibody (anti-HBc) in the era of prophylaxis with hepatitis IgG immunoglobulin and lamivudine. Transplantation 75(8), 1179–1186 (2003).
  • Fabrega E, Garcia-Suarez C, Guerra A, et al Liver transplantation with allografts from hepatitis B core antibody-positive donors: a new approach. Liver Transpl 9(9), 916–920 (2003).
  • Liao CA, Lee CM, Wu HC, Wang MC, Lu SN, Eng HL. Lamivudine for the treatment of hepatitis B virus reactivation following chemotherapy for non-Hodgkin's lymphoma. Br J. Haematol 116(1), 166–169 (2002).
  • Rossi G, Pelizzari A, Motta M, Puoti M. Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HBsAg carriers with lymphoid malignancies treated with chemotherapy. Br J. Haematol 115(1), 58–62 (2001).
  • Jonas MM, Kelly DA, Mizerski J, et al. and the International Paediatric Lamivudine Investigator Group. Clinical trial of lamivudine in children with chronic hepatitis B. N Engl J. Med. 346(22), 1706–1713. (Zucker SD. Commentary. All kidding aside with the use of lamivudine in children with chronic hepatitis B. Gastroenterology 123[5], 1741–1743) (2002).
  • Jonas MM, Kelly DA, Mizerski J, et al. and the International Paediatric Lamivudine Investigator Group. Extended lamivudine therapy in children with chronic hepatitis B. Hepatology 38(4) (Suppl. 1), 710A (2002).
  • Hartman C, Berkowitz D, Shouval DS, et al. Lamivudine treatment for chronic hepatitis B infection in children unresponsive to interferon. Pediat. Infect. Dis. J. 22(3), 224–229 (2003).
  • Leung NWY. Lamivudine therapy for children with chronic hepatitis B. J. Hepatol. 38, 698–701 (2003).
  • van Nunen AB, de Man R, Heijtink RA, Niesters HGM, Schalm SW. Lamivudine in the last 4 weeks of pregnancy to prevent perinatal transmission in highly viremic chronic hepatitis B virus patients. J. Hepatol. 32(6), 1040–1041 (2000) (Letter).
  • Kazim SN, Wakil SM, Khan LA, Hasnain SE, Sarin SK. Vertical transmission of hepatitis B virus despite maternal lamivudien therapy. Lancet 359, 1488–1489 (2002).
  • van Zonneveld M, van Nunen AB, Niesters HGM, de Man R, Schalm SW Janssen HLA. Lamivudine treatment during pregnancy to prevent perinatal transmission of hepatitis B virus infection. J. Viral. Hepatol. 10,294–297 (2003).
  • Li XIV', Yang YB, Hou HY, et al. Interruption of HBV intrauterine transmission, a clinical study. World J. Gastroenterol. 9(7), 1501–1503 (2003).
  • Lai CL, Leung NWY, Teo EK, et al. Results of a 1-year international Phase JIB comparative trial of telbivudine, lamivudine and the combination, in patients with chronic hepatitis B. Hepatology 38(4) (Suppl. 1), 262A (2003).
  • Schiff ER, DienstagJL, Karayalcin S, et al and the International Lamivudine Investigator Group. Lamivudine and 24 weeks of lamivudine/interferon combination therapy for hepatitis B e antigen-positive chronic hepatitis B in interferon nonresponders. HepatoL 38(6), 818–826 (2003).
  • Sung JJY, Chan HLY, Hui AY, et al. Combination of pegylated interferon and lamivudine is superior to lamivudine monotherapy in the treatment of chronic hepatitis B — a randomized trial. J. Hepatol. 38\(Suppl. 2), 33 (2003).
  • Marcellin P, Lau GKK, Bonino F, et al. A, Phase III, partially double-blinded study evaluating the efficacy and safety of peginterferon-ct, (40 KD) (Pegasis®) alone or in combination with lamivudine vs. lamivudine in 546 patients with HBeAg-negative/anti-HBe positive chronic hepatitis B. Hepatology 38(4) (Suppl. 1), 724A (2003).

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