Prevention and treatment of leptospirosis

References

• World Health Organization. Leptospirosis worldwide, 1999. WklyEpidemiol. Rec. 74,237–242 (1999).
   PubMedGoogle Scholar
• •Summary of global surveillance conducted by the International Leptospirosis Society.
   Google Scholar
• Edwards CN. `Leptospirosis'. In: Infectious Diseases. Cohen J, Powderly WG (Eds). Mosby, PA, USA (2004).
   Google Scholar
• Johnson RC, Faine S. Teptospird. In: Bergey's Manual of Systematic Bacteriology, Vol. 1. Krieg NR, Holt JG (Eds). Williams & Wilkins, BA, USA, 62–67 (1984).
   Google Scholar
• Dikken H, Kmety E. 'Serological typing methods of leptospires'. In: Methods in Microbiology Vol. 11. Bergan T, Norris JR (Eds). Academic Press, London, UK, 259–307 (1978).
   Google Scholar
• Terpstra WJ. Typing leptospira from the perspective of a reference laboratory. Acta Leiden. 60,79–87 (1992).
   PubMedGoogle Scholar
• Yasuda PH, Steigerwalt AG, Sulzer KR, Kaufmann AF, Rogers F, Brenner DJ. Deoxyribonucleic acid relatedness between serogroups and serovars in the family Leptospiraceae with proposals for seven new Leptospira species. Int. J. Syst. Bacterial. 37, 407–415 (1987).
   Google Scholar
• Ramadass R, Jarvis BDW, Corner RJ, Penny D, Marshall RB. Genetic characterization of pathogenic Leptospira species by DNA hybridization. Int. J. Syst. Bacterial. 42, 215–219 (1992).
   PubMedGoogle Scholar
• Brenner DJ, Kaufmann AF, Sulzer KR, Steigerwalt AG, Rogers FC, Weyant RS. Further determination of DNA relatedness between serogroups and serovars in the family Leptospinveae with a proposal for Leptospira alexanderi sp. nov. and four new Leptospira genomospecies. Int. J. Syst. Bacterial. 49,839–858 (1999).
   PubMedGoogle Scholar
• •Describes the molecular basis for modern taxonomy of Lepto.spira.
   Google Scholar
• Perolat P, Chappel RJ, Adler B, et al Leptospira fainei sp. nov., isolated from pigs in Australia. Int. J. Syst. Bacterial. 48,851–858 (1998).
   PubMedGoogle Scholar
• Levett PN. Leptospirosis. Clin. MicrobiaL Rev. 14,296–326 (2001).
   PubMed Web of Science ®Google Scholar
• ••Most current review of this field.
   Google Scholar
• Morgan J, Bornstein SL, Karpati AM, et al Outbreak of leptospirosis among Triathlon participants and community residents in Springfield, Illinois, 1998. Clin. Infect. Dis. 34,1593–1599 (2002).
   PubMed Web of Science ®Google Scholar
• •Describes the investigation of the largest outbreak of leptospirosis in North America.
   Google Scholar
• Sejvar J, Bancroft E, Winthrop K, et al Leptospirosis in Tco-Challenge athletes, Malaysian Borneo, 2000. Emerg. Infect. Dis. 9,702–707 (2003).
   PubMed Web of Science ®Google Scholar
• Sakamoto M, Sagara H, Koizumi N, Watanabe H. A case of leptospirosis infection in Borneo Island, Malaysia. Kansenshogaku Zasshi. 75,1057–1061 (2001).
   PubMedGoogle Scholar
• Evans M, Baranton G. Leptospirosis outbreak in Eco Challenge 2000 participants. EurosurveiL Wkly (2000).
   Google Scholar
• Douglin CP, Jordan C, Rock R, Hurley A, Levett PN. Risk factors for severe leptospirosis in the parish of St. Andrew, Barbados. Emerg Infect. Dis. 3,78–80 (1997).
   PubMedGoogle Scholar
• Ko Al, Galva° O; Reis M, Ribeiro Dourado CM, Johnson WD, Riley LW Salvador Leptospirosis Study Group. Urban epidemic of severe leptospirosis in Brazil. Lancet 354, 820–825 (1999).
   PubMed Web of Science ®Google Scholar
• Vinetz JM, Glass GE, Flexner CE, Mueller 794–798 (1996).
   Google Scholar
• Trevejo RT, Rigau-Perez JG, Ashford DA, et al. Epidemic leptospirosis associated with pulmonary hemorrhage — Nicaragua, 1995.J. Infect. Dis. 178,1457–1463 (1998).
   PubMed Web of Science ®Google Scholar
• •Describes an outbreak of leptospirosis in Nicaragua.
   Google Scholar
• Pan American Health Organization. Impact of Hurricane Mitch on Central America. EpidemiaL Bull. 19,1–13 (1998).
   Google Scholar
• World Health Organization. Leptospirosis, India. Report of the investigation of a post-cyclone outbreak in Orissa, November 1999. Wkly EpidemiaL Rec. 75,217–223 (2000).
   Google Scholar
• Sanders EJ, Rigau-Perez JG, Smits HL, et al. Increase of leptospirosis in dengue-negative patients after a hurricane in Puerto Rico in 1996. Am. J. Trap. Med. Hyg. 61,399–404 (1999).
   Google Scholar
• Bharti AR, Nally JE, RicaMi JN, et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect. Dis. 3,757–771 (2003).
   PubMed Web of Science ®Google Scholar
• Brown CA, Roberts AW, Miller MA, et al. Leptospira interrogans serovar Grippotyphosa infection in dogs. J. Am. Vet. Med. Assoc. 209,1265–1267 (1996).
   PubMedGoogle Scholar
• Birnbaum N, Barr SC, Center SA, Schermerhorn T, Randolph JF, Simpson KW. Naturally acquired leptospirosis in 36 dogs: serological and dinicopathological features. J. Small Animal Prac. 39, 231–236 (1998).
   PubMed Web of Science ®Google Scholar
• Prescott JF, McEwen B, Taylor J, Woods JP, Abrams-Ogg A, Wilcock B. Resurgence of leptospirosis in dogs in Ontario: recent findings. Can. vet.J. 43,955–961 (2002).
   PubMedGoogle Scholar
• Faine S, Adler B, Bolin C, Perolat Leptospira and leptospirosis, 2nd Edition. MedSci, Melbourne, Australia (1999). Most complete monograph on all aspects of leptospirosis.
   Google Scholar
• Matthias MA, Levett PN. Leptospiral carriage by mice and mongooses on the island of Barbados. W Indian Med. J. 51, 10–13 (2002).
   Google Scholar
• Naiman BM, Alt D, Bolin CA, Zuerner R, Baldwin CL. Protective killed Leptospira borgpetersenii vaccine induces potent Thl immunity comprising responses by CD4 and gammadelta T-lymphocytes. Infect. Immun. 69,7550–7558 (2001).
   PubMed Web of Science ®Google Scholar
• ••Demonstrates the occurrence of a cell-mediated immune response in leptospirosis.
   Google Scholar
• Bolin CA, Alt DR Use of a monovalent leptospiral vaccine to prevent renal colonization and urinary shedding in cattle exposed to Leptospira borgpetersenii serovar hardjo. Am. J. Vet. Res. 62, 995–1000 (2001).
   PubMed Web of Science ®Google Scholar
• •Shows the potential for immunization to prevent renal infection and shedding.
   Google Scholar
• Martinez Sanchez R, Perez Sierra A, Bare Suarez M, et al. Evaluación de la efectividad de una nueva vacuna contra la leptospirosis humana en grupos en riesgo. Pan. Am. J. Public Health 8,385–392 (2000).
   Google Scholar
• Takafuji ET, Kirkpatrick JW, Miller RN, et al. An efficacy trial of doxycycline chemoprophylaxis against leptospirosis. N EngL J. Med. 310,497–500 (1984).
   PubMed Web of Science ®Google Scholar
• ••Demonstrates the value of doxycyclineprophylaxis in healthy young adults.
   Google Scholar
• Gonsalez CR, Casseb J, Monteiro FG, et al. Use of doxycycline for leptospirosis after high-risk exposure in Sao Paulo, Brazil. Rev. Inst. Med.Trop. Sao Paulo. 41, 59–61 (1998).
   Google Scholar
• Sehgal SC, Sugunan AP, Murhekar MV, Sharma S, Vijayachari R Randomized controlled trial of doxycycline prophylaxis against leptospirosis in an endemic area. Int. J. Antimicrob. Agents. 13,249–255 (2000).
   PubMed Web of Science ®Google Scholar
• McClain JBL, Ballou WR, Harrison SM, Steinweg DL. Doxycycline therapy for leptospirosis. Ann. Int. Med. 100, 696–698 (1984).
   PubMed Web of Science ®Google Scholar
• ••Describes a randomized, double-blind, placebo-controlled trial of doxycycline.
   Google Scholar
• Edwards CN, Nicholson GD, Hassell TA, Everard COR, Callender J. Leptospirosis in Barbados: a clinical study. W Indian Med. J. 39,27–34 (1990).
   Google Scholar
• Tse KC, Yip PS, Hui KM, et al. Potential benefit of plasma exchange in treatment of severe icteric leptospirosis complicated by acute renal failure. Clin. Diagn. Lab. ImmunoL 9,482–484 (2002).
   PubMedGoogle Scholar
• Borer A, Metz I, Gilad J, et al Massive pulmonary hemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration. J. Infect. 38,42–45 (1999).
   PubMed Web of Science ®Google Scholar
• Pea L, Roda L, Boussaud V, Lonjon B. Desmopressin therapy for massive hemoptysis associated with severe leptospirosis. Am. J. Rev. Crit. Care Med. 167,726–728 (2003).
   PubMed Web of Science ®Google Scholar
• Guidugli F, Castro AA, Atallah AN. Antibiotics for treating leptospirosis (Cochrane Review). In: Cochrane Library, Issue 3. Oxford: Update Software (2003).
   Google Scholar
• ••Meta-analysis of treatment studies.
   Google Scholar
• Edwards CN, Nicholson GD, Hassell TA, Everard COR, Callender J. Penicillin therapy in icteric leptospirosis. Am. J. Prop. Med. Hyg. 39,388–390 (1988).
   PubMedGoogle Scholar
• •• Describes a randomized placebo-controlled trial of penicillin in patients with severe, icteric leptospirosis.
   Google Scholar
• Watt G, Padre LP, Tuazon ML, et al. Placebo-controlled trial of intravenous penicillin for severe and late leptospirosis. Lancet 433–435 (1988).
   PubMedGoogle Scholar
• •• Describes a randomized, double-blind, placebo-controlled trial of penicillin.
   Google Scholar
• Costa E, Lopes AA, Sacramento E, et al. Penicillin at the late stage ofleptospirosis: a randomized controlled trial. Rev. Inst. Med. Prop. Sao Paulo 45,141–145 (2003).
   PubMedGoogle Scholar
• •• Describes a large, randomized placebo-controlled trial of penicillin in patients with severe, icteric leptospirosis.
   Google Scholar
• Vientz J. A mountain out of a molehill: do we treat acute leptospirosis and if so, with what? Clin. Infect. Dis. 36, 1514–1515 (2003).
   PubMedGoogle Scholar
• Panaphut T, Domrongkitchaiporn S, Vibhagool A, Thinkamrop B, Susaengrat W. Ceftriaxone compared with sodium penicillin G for treatment of severe leptospirosis. Clin. Infect. Dis. 36, 1507–1513 (2003).
   PubMed Web of Science ®Google Scholar
• •• Describes a large, randomized trial of penicillin versus ceftriaxone.
   Google Scholar