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Reviews

The spread and acquisition of NDM-1: a multifactorial problem

Alexander M WailanThe University of Queensland, UQ Centre for Clinical Research, Herston QLD 4029, Australia.
&
David L PatersonCorrespondence[email protected]
Pages 91-115 | Published online: 26 Nov 2013

References

  • Alekshun MN, Levy SB. Molecular mechanisms of antibacterial multidrug resistance. Cell 128(6), 1037–1050 (2007).
  • Mingeot-Leclercq MP, Glupczynski Y, Tulkens PM. Aminoglycosides: activity and resistance. Antimicrob. Agents Chemother. 43(4), 727–737 (1999).
  • Yong D, Toleman MA, Giske CG et al. Characterization of a new metallo-beta-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob. Agents Chemother. 53(12), 5046–5054 (2009).
  • Walsh TR, Weeks J, Livermore DM, Toleman MA. Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study. Lancet Infect. Dis. 11(5), 355–362 (2011).
  • Escobar PJA, Olarte ENM, Castro-Cardozo B et al. Outbreak of NDM-1-Producing Klebsiella pneumoniae in a Neonatal Unit in Colombia. Antimicrob. Agents Chemother. 57(4), 1957–1960 (2013).
  • Poirel L, Revathi G, Bernabeu S, Nordmann P. Detection of NDM-1-producing Klebsiella pneumoniae in Kenya. Antimicrob. Agents Chemother. 55(2), 934–936 (2011).
  • Chen Y, Zhou Z, Jiang Y, Yu Y. Emergence of NDM-1-producing Acinetobacter baumannii in China. J. Antimicrob. Chemother. 66(6), 1255–1259 (2011).
  • Sole M, Pitart C, Roca I et al. First description of an Escherichia coli strain producing NDM-1 carbapenemase in Spain. Antimicrob. Agents Chemother. 55(9), 4402–4404 (2011).
  • Bogaerts P, Bouchahrouf W, De CRR et al. Emergence of NDM-1-producing Enterobacteriaceae in Belgium. Antimicrob. Agents Chemother. 55(6), 3036–3038 (2011).
  • Poirel L, Ros A, Carricajo A et al. Extremely drug-resistant Citrobacter freundii isolate producing NDM-1 and other carbapenemases identified in a patient returning from India. Antimicrob. Agents Chemother. 55(1), 447–448 (2011).
  • Kumarasamy KK, Toleman MA, Walsh TR et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect. Dis. 10(9), 597–602 (2010).
  • Samuelsen O, Naseer U, Karah N et al. Identification of Enterobacteriaceae isolates with OXA-48 and coproduction of OXA-181 and NDM-1 in Norway. J. Antimicrob. Chemother. 68(7), 1682–1685 (2013).
  • Poirel L, Benouda A, Hays C, Nordmann P. Emergence of NDM-1-producing Klebsiella pneumoniae in Morocco. J. Antimicrob. Chemother. 66(12), 2781–2783 (2011).
  • Zowawi HM, Balkhy HH, Walsh TR, Paterson DL. β-Lactamase production in key gram-negative pathogen isolates from the Arabian peninsula. Clin. Microbiol. Rev. 26(3), 361–380 (2013).
  • Bogaerts P, Rezende DCR, Roisin S et al. Emergence of NDM-1-producing Acinetobacter baumannii in Belgium. J. Antimicrob. Chemother. 67(6), 1552–1553 (2012).
  • Birgy A, Doit C, Mariani-Kurkdjian P et al. Early detection of colonization by VIM-1-producing Klebsiella pneumoniae and NDM-1-producing Escherichia coli in two children returning to France. J. Clin. Microbiol. 49(8), 3085–3087 (2011).
  • Hrabak J, Stolbova M, Studentova V, Fridrichova M, Chudackova E, Zemlickova H. NDM-1 producing Acinetobacter baumannii isolated from a patient repatriated to the Czech Republic from Egypt, July 2011. Euro Surveill. 17(7) (2012).
  • Poirel L, Fortineau N, Nordmann P. International transfer of NDM-1-producing Klebsiella pneumoniae from Iraq to France. Antimicrob. Agents Chemother. 55(4), 1821–1822 (2011).
  • El-Herte RI, Araj GF, Matar GM, Baroud M, Kanafani ZA, Kanj SS. Detection of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae producing NDM-1 in Lebanon. J. Infect. Dev. Ctries. 6(5), 457–461 (2012).
  • Jamal W, Rotimi VO, Albert MJ, Khodakhast F, Udo EE, Poirel L. Emergence of nosocomial New Delhi metallo-beta-lactamase-1 (NDM-1)-producing Klebsiella pneumoniae in patients admitted to a tertiary care hospital in Kuwait. Int. J. Antimicrob. Agents 39(2), 183–184 (2012).
  • Dortet L, Poirel L, Al YF, Nordmann P. NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman. Clin. Microbiol. Infect. 18(5), e144–e148 (2012).
  • Baroud M, Dandache I, Araj GF et al. Underlying mechanisms of carbapenem resistance in extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli isolates at a tertiary care centre in Lebanon: role of OXA-48 and NDM-1 carbapenemases. Int. J. Antimicrob. Agents 41(1), 75–79 (2013).
  • Mcgann P, Hang J, Clifford RJ et al. Complete sequence of a novel 178-kilobase plasmid carrying blaNDM-1 in a Providencia stuartii strain isolated in Afghanistan. Antimicrob. Agents Chemother. 56(4), 1673–1679 (2012).
  • Kim MN, Yong D, An D et al. Nosocomial clustering of NDM-1-producing Klebsiella pneumoniae sequence type 340 strains in four patients at a South Korean tertiary care hospital. J. Clin. Microbiol. 50(4), 1433–1436 (2012).
  • Chien JM, Koh TH, Chan KS, Chuah TH, Tan TT. Successful treatment of NDM-1 Klebsiella pneumoniae bacteraemia in a neutropenic patient. Scand. J. Infect. Dis. 44(4), 312–314 (2012).
  • Denis C, Poirel L, Carricajo A et al. Nosocomial transmission of NDM-1-producing Escherichia coli within a non-endemic area in France. Clin. Microbiol. Infect. 18(5), e128–e130 (2012).
  • Gaibani P, Ambretti S, Berlingeri A et al. Outbreak of NDM-1-producing Enterobacteriaceae in northern Italy, July to August 2011. Euro Surveill. 16(47), 20027 (2011).
  • Barantsevich EP, Churkina IV, Barantsevich NE, Pelkonen J, Schlyakhto EV, Woodford N. Emergence of Klebsiella pneumoniae producing NDM-1 carbapenemase in Saint Petersburg, Russia. J. Antimicrob. Chemother. 68(5), 1204–1206 (2013).
  • Pasteran F, Albornoz E, Faccone D et al. Emergence of NDM-1-producing Klebsiella pneumoniae in Guatemala. J. Antimicrob. Chemother. 67(7), 1795–1797 (2012).
  • Williamson DA, Sidjabat HE, Freeman JT et al. Identification and molecular characterisation of New Delhi metallo-beta-lactamase-1 (NDM-1)- and NDM-6-producing Enterobacteriaceae from New Zealand hospitals. Int. J. Antimicrob. Agents 39(6), 529–533 (2012).
  • Sidjabat H, Nimmo GR, Walsh TR et al. Carbapenem resistance in Klebsiella pneumoniae due to the New Delhi Metallo-beta-lactamase. Clin. Infect. Dis. 52(4), 481–484 (2011).
  • Mochon AB, Garner OB, Hindler JA et al. New Delhi metallo-beta-lactamase (NDM-1)-producing Klebsiella pneumoniae: case report and laboratory detection strategies. J. Clin. Microbiol. 49(4), 1667–1670 (2011).
  • Wang Y, Wu C, Zhang Q et al. Identification of New Delhi metallo-beta-lactamase 1 in Acinetobacter lwoffii of food animal origin. PLoS ONE 7(5), e37152 (2012).
  • Castanheira M, Deshpande LM, Farrell SE, Shetye S, Shah N, Jones RN. Update on the prevalence and genetic characterization of NDM-1-producing Enterobacteriaceae in Indian hospitals during 2010. Diagn. Microbiol. Infect. Dis. 75(2), 210–213 (2013).
  • Poirel L, Dortet L, Bernabeu S, Nordmann P. Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrob. Agents Chemother. 55(11), 5403–5407 (2011).
  • Poirel L, Al Maskari Z, Al Rashdi F, Bernabeu S, Nordmann P. NDM-1-producing Klebsiella pneumoniae isolated in the Sultanate of Oman. J Antimicrob. Chemother. 66(2), 304–306 (2011).
  • Poirel L, Schrenzel J, Cherkaoui A, Bernabeu S, Renzi G, Nordmann P. Molecular analysis of NDM-1-producing enterobacterial isolates from Geneva, Switzerland. J. Antimicrob. Chemother. 66(8), 1730–1733 (2011).
  • Lascols C, Hackel M, Marshall SH et al. Increasing prevalence and dissemination of NDM-1 metallo-beta-lactamase in India: data from the SMART study (2009). J. Antimicrob. Chemother. 66(9), 1992–1997 (2011).
  • Giske CG, Froding I, Hasan CM et al. Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of blaNDM-1 in India, Sweden, and the United Kingdom. Antimicrob. Agents Chemother. 56(5), 2735–2738 (2012).
  • Halaby T, Reuland AE, Al NN et al. A case of New Delhi metallo-beta-lactamase 1 (NDM-1)-producing Klebsiella pneumoniae with putative secondary transmission from the Balkan region in the Netherlands. Antimicrob. Agents Chemother. 56(5), 2790–2791 (2012).
  • Arpin C, Noury P, Boraud D et al. NDM-1-producing Klebsiella pneumoniae resistant to colistin in a French community patient without history of foreign travel. Antimicrob. Agents Chemother. 56(6), 3432–3434 (2012).
  • Poirel L, Lascols C, Bernabeu S, Nordmann P. NDM-1-producing Klebsiella pneumoniae in Mauritius. Antimicrob. Agents Chemother. 56(1), 598–599 (2012).
  • Poirel L, Ozdamar M, Ocampo-Sosa AA, Turkoglu S, Ozer UG, Nordmann P. NDM-1-producing Klebsiella pneumoniae now in Turkey. Antimicrob. Agents Chemother. 56(5), 2784–2785 (2012).
  • Yamamoto T, Takano T, Fusegawa T et al. Electron microscopic structures, serum resistance, and plasmid restructuring of New Delhi metallo-beta-lactamase-1 (NDM-1)-producing ST42 Klebsiella pneumoniae emerging in Japan. J. Infect. Chemother. 19(1), 118–127 (2013).
  • Nordmann P, Couard JP, Sansot D, Poirel L. Emergence of an autochthonous and community-acquired NDM-1-producing Klebsiella pneumoniae in Europe. Clin. Infect. Dis. 54(1), 150–151 (2012).
  • Ahmed-Bentley J, Chandran AU, Joffe AM, French D, Peirano G, Pitout JD. Gram-negative bacteria that produce carbapenemases causing death attributed to recent foreign hospitalization. Antimicrob. Agents Chemother. 57(7), 3085–3091 (2013).
  • Mazzariol A, Bosnjak Z, Ballarini P et al. NDM-1-producing Klebsiella pneumoniae, Croatia. Emerg. Infect. Dis. 18(3), 532–534 (2012).
  • Isozumi R, Yoshimatsu K, Yamashiro T et al. blaNDM-1-positive Klebsiella pneumoniae from environment, Vietnam. Emerg. Infect. Dis. 18(8), 1383–1385 (2012).
  • Ho PL, Li Z, Lai EL, Chiu SS, Cheng VC. Emergence of NDM-1-producing Enterobacteriaceae in China. J. Antimicrob. Chemother. 67(6), 1553–1555 (2012).
  • Nielsen JB, Hansen F, Littauer P, Schonning K, Hammerum AM. An NDM-1-producing Escherichia coli obtained in Denmark has a genetic profile similar to an NDM-1-producing E. coli isolate from the UK. J. Antimicrob. Chemother. 67(8), 2049–2051 (2012).
  • Castanheira M, Deshpande LM, Mathai D, Bell JM, Jones RN, Mendes RE. Early Dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian Hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006-2007. Antimicrob. Agents Chemother. 55(3), 1274–1278 (2011).
  • Poirel L, Lagrutta E, Taylor P, Pham J, Nordmann P. Emergence of metallo-beta-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia. Antimicrob. Agents Chemother. 54(11), 4914–4916 (2010).
  • Pfeifer Y, Witte W, Holfelder M, Busch J, Nordmann P, Poirel L. NDM-1-Producing Escherichia coli in Germany. Antimicrob. Agents Chemother. 55(3), 1318–1319 (2011).
  • Dortet L, Poirel L, Anguel N, Nordmann P. New Delhi metallo-beta-lactamase 4-producing Escherichia coli in Cameroon. Emerg. Infect. Dis. 18(9), 1540–1542 (2012).
  • Mushtaq S, Irfan S, Sarma JB et al. Phylogenetic diversity of Escherichia coli strains producing NDM-type carbapenemases. J. Antimicrob. Chemother. 66(9), 2002–2005 (2011).
  • Samuelsen O, Thilesen CM, Heggelund L, Vada AN, Kummel A, Sundsfjord A. Identification of NDM-1-producing Enterobacteriaceae in Norway. J. Antimicrob. Chemother. 66(3), 670–672 (2011).
  • Peirano G, Schreckenberger PC, Pitout JD. Characteristics of NDM-1-producing Escherichia coli isolates that belong to the successful and virulent clone ST131. Antimicrob. Agents Chemother. 55(6), 2986–2988 (2011).
  • Poirel L, Herve V, Hombrouck-Alet C, Nordmann P. Long-term carriage of NDM-1-producing Escherichia coli. J. Antimicrob. Chemother. 66(9), 2185–2186 (2011).
  • Yamamoto T, Takano T, Iwao Y, Hishinuma A. Emergence of NDM-1-positive capsulated Escherichia coli with high resistance to serum killing in Japan. J. Infect. Chemother. 17(3), 435–439 (2011).
  • Totsika M, Beatson SA, Sarkar S et al. Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms. PloS ONE 6(10), e26578 (2011).
  • Perry JD, Naqvi SH, Mirza IA et al. Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media. J. Antimicrob. Chemother. 66(10), 2288–2294 (2011).
  • Lai CC, Lin TL, Tseng SP et al. Pelvic abscess caused by New Delhi metallo-beta-lactamase-1-producing Klebsiella oxytoca in Taiwan in a patient who underwent renal transplantation in China. Diagn. Microbiol. Infect. Dis. 71(4), 474–475 (2011).
  • Mirovic V, Tomanovic B, Lepsanovic Z, Jovcic B, Kojic M. Isolation of Klebsiella pneumoniae producing NDM-1 metallo-beta-lactamase from the urine of an outpatient baby boy receiving antibiotic prophylaxis. Antimicrob. Agents Chemother. 56(11), 6062–6063 (2012).
  • Islam MA, Talukdar PK, Hoque A et al. Emergence of multidrug-resistant NDM-1-producing Gram-negative bacteria in Bangladesh. Eur. J. Clin. Microbiol. Infect. Dis. 31(10), 2593–2600 (2012).
  • Cabanes F, Lemant J, Picot S et al. Emergence of Klebsiella pneumoniae and Salmonella metallo-beta-lactamase (NDM-1) producers on reunion island. J. Clin. Microbiol. 50(11), 3812 (2012).
  • Bogaerts P, Huang TD, Rezende DCR, Bouchahrouf W, Glupczynski Y. Could Acinetobacter pittii act as an NDM-1 reservoir for Enterobacteriaceae? J. Antimicrob. Chemother. 68(10), 2414–2415 (2013).
  • Toleman MA, Spencer J, Jones L, Walsh TR. blaNDM-1 is a chimera likely constructed in Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(5), 2773–2776 (2012).
  • Nakazawa Y, Ii R, Tamura T et al. A case of NDM-1-producing Acinetobacter baumannii transferred from India to Japan. J. Infect. Chemother. 19(2), 330–332 (2012).
  • Zong Z, Zhang X. blaNDM-1-carrying Acinetobacter johnsonii detected in hospital sewage. J. Antimicrob. Chemother. 68(5), 1007–1010 (2013).
  • Zhou Z, Guan R, Yang Y et al. Identification of New Delhi metallo-beta-lactamase gene (NDM-1) from a clinical isolate of Acinetobacter junii in China. Can. J. Microbiol. 58(1), 112–115 (2012).
  • Hu H, Hu Y, Pan Y et al. Novel plasmid and its variant harboring both a blaNDM-1 gene and type IV secretion system in clinical isolates of Acinetobacter lwoffii. Antimicrob. Agents Chemother. 56(4), 1698–1702 (2012).
  • Yang J, Chen Y, Jia X et al. Dissemination and characterization of NDM-1-producing Acinetobacter pittii in an intensive care unit in China. Clin. Microbiol. Infect. 18(12), e506–e513 (2012).
  • Janvier F, Jeannot K, Tesse S et al. Molecular characterization of blaNDM-1 in a Sequence Type 235 Pseudomonas aeruginosa isolate from France. Antimicrob. Agents Chemother. 57(7), 3408–3411 (2013).
  • Maatallah M, Cheriaa J, Backhrouf A et al. Population structure of Pseudomonas aeruginosa from five Mediterranean countries: evidence for frequent recombination and epidemic occurrence of CC235. PloS ONE 6(10), e25617 (2011).
  • Zhang C, Qiu S, Wang Y et al. Higher isolation of NDM-1 producing Acinetobacter baumannii from the sewage of the hospitals in Beijing. PloS ONE 8(6), e64857 (2013).
  • Libisch B, Poirel L, Lepsanovic Z et al. Identification of PER-1 extended-spectrum beta-lactamase producing Pseudomonas aeruginosa clinical isolates of the international clonal complex CC11 from Hungary and Serbia. FEMS Immunol. Med. Microbiol. 54(3), 330–338 (2008).
  • Lanka E, Barth PT. Plasmid RP4 specifies a deoxyribonucleic acid primase involved in its conjugal transfer and maintenance. J. Bacteriol. 148(3), 769–781 (1981).
  • Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. Identification of plasmids by PCR-based replicon typing. J. Microbiol. Methods 63(3), 219–228 (2005).
  • Dolejska M, Villa L, Poirel L, Nordmann P, Carattoli A. Complete sequencing of an IncHI1 plasmid encoding the carbapenemase NDM-1, the ArmA 16S RNA methylase and a resistance-nodulation-cell division/multidrug efflux pump. J. Antimicrob. Chemother. 68(1), 34–39 (2013).
  • Han SH, Kim YA, Wang M et al. Comparison of the genetic structures surrounding qnrA1 in Korean Enterobacter cloacae and Chinese Escherichia coli strains isolated in the early 2000s: evidence for qnrA mobilization via Inc HI2 type plasmid. J. Microbiol. 50(1), 166–169 (2012).
  • Stone NR, Woodford N, Livermore DM et al. Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo-beta-lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis. J. Antimicrob. Chemother. 66(11), 2677–2678 (2011).
  • Chatfield LK, Orr E, Boulnois GJ, Wilkins BM. DNA primase of plasmid ColIb is involved in conjugal DnA synthesis in donor and recipient bacteria. J. Bacteriol. 152(3), 1188–1195 (1982).
  • Garcillan-Barcia MP, Alvarado A, De LCF. Identification of bacterial plasmids based on mobility and plasmid population biology. FEMS Microbiol. Rev. 35(5), 936–956 (2011).
  • Toleman MA, Bennett PM, Walsh TR. ISCR elements: novel gene-capturing systems of the 21st century? Microbiol. Mol. Biol. Rev. 70(2), 296–316 (2006).
  • Poirel L, Bonnin RA, Boulanger A, Schrenzel J, Kaase M, Nordmann P. Tn125-related acquisition of blaNDM-like genes in Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(2), 1087–1089 (2012).
  • Jovcic B, Lepsanovic Z, Suljagic V et al. Emergence of NDM-1 metallo-beta-lactamase in Pseudomonas aeruginosa clinical isolates from Serbia. Antimicrob. Agents Chemother. 55(8), 3929–3931 (2011).
  • Pfeifer Y, Wilharm G, Zander E et al. Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007. J. Antimicrob. Chemother. 66(9), 1998–2001 (2011).
  • Dortet L, Nordmann P, Poirel L. Association of the emerging carbapenemase NDM-1 with a bleomycin resistance protein in Enterobacteriaceae and Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(4), 1693–1697 (2012).
  • Walsh TR, Toleman MA. The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response. J. Antimicrob. Chemother. 67(1), 1–3 (2012).
  • Nordmann P, Poirel L, Dortet L. Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg. Infect. Dis. 18(9), 1503–1507 (2012).
  • Peirano G, Pillai DR, Pitondo-Silva A, Richardson D, Pitout JD. The characteristics of NDM-producing Klebsiella pneumoniae from Canada. Diagn. Microbiol. Infect. Dis. 71(2), 106–109 (2011).
  • Peirano G, Ahmed-Bentley J, Woodford N, Pitout JD. New Delhi metallo-beta-lactamase from traveler returning to Canada. Emerg. Infect. Dis. 17(2), 242–244 (2011).
  • Rogers BA, Sidjabat HE, Silvey A et al. Treatment options for New Delhi metallo-beta-lactamase-harboring enterobacteriaceae. Microb. Drug Resist. 19(2), 100–103 (2013).
  • Garonzik SM, Li J, Thamlikitkul V et al. Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrob. Agents Chemother. 55(7), 3284–3294 (2011).
  • Tumbarello M, Viale P, Viscoli C et al. Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy. Clin. Infect. Dis. 55(7), 943–950 (2012).
  • Zarkotou O, Pournaras S, Tselioti P et al. Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment. Clin. Microbiol. Infect. 17(12), 1798–1803 (2011).
  • Qureshi ZA, Paterson DL, Potoski BA et al. Treatment outcome of bacteremia due to KPC-producing Klebsiella pneumoniae: superiority of combination antimicrobial regimens. Antimicrob. Agents Chemother. 56(4), 2108–2113 (2012).
  • Darley E, Weeks J, Jones L et al. NDM-1 polymicrobial infections including Vibrio cholerae. Lancet 380(9850), 1358 (2012).
  • D’andrea MM, Venturelli C, Giani T et al. Persistent carriage and infection by multidrug-resistant Escherichia coli ST405 producing NDM-1 carbapenemase: report on the first Italian cases. J. Clin. Microbiol. 49(7), 2755–2758 (2011).
  • Oteo J, Domingo-Garcia D, Fernandez-Romero S et al. Abdominal abscess due to NDM-1-producing Klebsiella pneumoniae in Spain. J. Med. Microbiol. 61(Pt 6), 864–867 (2012).
  • Tsang KY, Luk S, Lo JY, Tsang TY, Lai ST, Ng TK. Hong Kong experiences the ‘Ultimate superbug’: NDM-1 Enterobacteriaceae. Hong Kong Med. J. 18(5), 439–441 (2012).
  • Chan HL, Poon LM, Chan SG, Teo JW. The perils of medical tourism: NDM-1-positive Escherichia coli causing febrile neutropenia in a medical tourist. Singapore Med. J. 52(4), 299–302 (2011).
  • Papagiannitsis CC, Studentova V, Chudackova E et al. Identification of a New Delhi metallo-beta-lactamase-4 (NDM-4)-producing Enterobacter cloacae from a Czech patient previously hospitalized in Sri Lanka. Folia Microbiol. (Praha) 58, 547–549 (2013).
  • Flateau C, Janvier F, Delacour H et al. Recurrent pyelonephritis due to NDM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in a patient returning from Serbia, France, 2012. Euro Surveill. 17(45) (2012).
  • Chen YT, Lin AC, Siu LK, Koh TH. Sequence of closely related plasmids encoding blaNDM-1 in two unrelated Klebsiella pneumoniae isolates in Singapore. PLoS ONE 7(11), e48737 (2012).
  • Roy S, Singh AK, Viswanathan R, Nandy RK, Basu S. Transmission of imipenem resistance determinants during the course of an outbreak of NDM-1 Escherichia coli in a sick newborn care unit. J. Antimicrob. Chemother. 66(12), 2773–2780 (2011).
  • Hidalgo L, Hopkins KL, Gutierrez B et al. Association of the novel aminoglycoside resistance determinant RmtF with NDM carbapenemase in Enterobacteriaceae isolated in India and the UK. J. Antimicrob. Chemother. 68(7), 1543–1550 (2013).
  • Hammerum AM, Larsen AR, Hansen F et al. Patients transferred from Libya to Denmark carried OXA-48-producing Klebsiella pneumoniae, NDM-1-producing Acinetobacter baumannii and meticillin-resistant Staphylococcus aureus. Int. J. Antimicrob. Agents 40(2), 191–192 (2012).
  • Mcdermott H, Morris D, Mcardle E et al. Isolation of NDM-1-producing Klebsiella pnemoniae in Ireland, July 2011. Euro surveillance : bulletin europeen sur les maladies transmissibles = European communicable disease bulletin 17(7) (2012).
  • Murali S, Jambulingam M, Tiru V et al. A study on isolation rate and prevalence of drug resistance among microorganisms isolated from multiorgan donor and donor corneal rim along with a report on existence of bla NDM-1 among Indian population. Curr. Eye Res. 37(3), 195–203 (2012).
  • Roy S, Viswanathan R, Singh AK, Das P, Basu S. Sepsis in neonates due to imipenem-resistant Klebsiella pneumoniae producing NDM-1 in India. J. Antimicrob. Chemother. 66(6), 1411–1413 (2011).
  • Kumarasamy K, Kalyanasundaram A. Emergence of Klebsiella pneumoniae isolate co-producing NDM-1 with KPC-2 from India. J. Antimicrob. Chemother. 67(1), 243–244 (2012).
  • Seema K, Ranjan SM, Upadhyay S, Bhattacharjee A. Dissemination of the New Delhi metallo-beta-lactamase-1 (NDM-1) among Enterobacteriaceae in a tertiary referral hospital in north India. J. Antimicrob. Chemother. 66(7), 1646–1647 (2011).
  • Sarma JB, Bhattacharya PK, Kalita D, Rajbangshi M. Multidrug-resistant Enterobacteriaceae including metallo-beta-lactamase producers are predominant pathogens of healthcare-associated infections in an Indian teaching hospital. Indian J. Med. Microbiol. 29(1), 22–27 (2011).
  • Bharadwaj R, Joshi S, Dohe V, Gaikwad V, Kulkarni G, Shouche Y. Prevalence of New Delhi metallo-beta-lactamase (NDM-1)-positive bacteria in a tertiary care centre in Pune, India. Int. J. Antimicrob. Agents 39(3), 265–266 (2012).
  • Islam MA, Huq M, Nabi A et al. Occurrence and characterization of multidrug-resistant New Delhi metallo-beta-lactamase-1-producing bacteria isolated between 2003 and 2010 in Bangladesh. J. Med. Microbiol. 62(Pt 1), 62–68 (2013).
  • Rimrang B, Chanawong A, Lulitanond A et al. Emergence of NDM-1- and IMP-14a-producing Enterobacteriaceae in Thailand. J. Antimicrob. Chemother. 67(11), 2626–2630 (2012).
  • Boulanger A, Naas T, Fortineau N, Figueiredo S, Nordmann P. NDM-1-producing Acinetobacter baumannii from Algeria. Antimicrob. Agents Chemother. 56(4), 2214–2215 (2012).
  • Carvalho-Assef AP, Pereira PS, Albano RM et al. Isolation of NDM-producing Providencia rettgeri in Brazil. J. Antimicrob. Chemother. doi:10.1093/jac/dkt298 (2013) ( Epub ahead of print).
  • Brink AJ, Coetzee J, Clay CG et al. Emergence of New Delhi metallo-beta-lactamase (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC-2) in South Africa. J. Clin. Microbiol. 50(2), 525–527 (2012).
  • Leski T, Vora GJ, Taitt CR. Multidrug resistance determinants from NDM-1-producing Klebsiella pneumoniae in the USA. Int. J. Antimicrob. Agents 40(3), 282–284 (2012).
  • Carattoli A, Villa L, Poirel L, Bonnin RA, Nordmann P. Evolution of IncA/C blaCMY-2-carrying plasmids by acquisition of the blaNDM-1 carbapenemase gene. Antimicrob. Agents Chemother. 56(2), 783–786 (2012).
  • Chihara S, Okuzumi K, Yamamoto Y, Oikawa S, Hishinuma A. First case of New Delhi metallo-beta-lactamase 1-producing Escherichia coli infection in Japan. Clin. Infect. Dis. 52(1), 153–154 (2011).
  • Sekizuka T, Matsui M, Yamane K et al. Complete sequencing of the blaNDM-1-positive IncA/C plasmid from Escherichia coli ST38 isolate suggests a possible origin from plant pathogens. PLoS ONE 6(9), e25334 (2011).
  • Bonnin RA, Poirel L, Naas T et al. Dissemination of New Delhi metallo-beta-lactamase-1-producing Acinetobacter baumannii in Europe. Clin. Microbiol. Infect. 18(9), e362–e365 (2012).
  • Tijet N, Alexander DC, Richardson D et al. New Delhi metallo-beta-lactamase, Ontario, Canada. Emerg. Infect. Dis. 17(2), 306–307 (2011).
  • Poirel L, Bonnin RA, Nordmann P. Analysis of the resistome of a multidrug-resistant NDM-1-producing Escherichia coli strain by high-throughput genome sequencing. Antimicrob. Agents Chemother. 55(9), 4224–4229 (2011).
  • Ho PL, Lo WU, Yeung MK et al. Complete sequencing of pNDM-HK encoding NDM-1 carbapenemase from a multidrug-resistant Escherichia coli strain isolated in Hong Kong. PLoS ONE 6(3), e17989 (2011).
  • Bonnin RA, Poirel L, Carattoli A, Nordmann P. Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131. PLoS ONE 7(4), e34752 (2012).
  • Villa L, Poirel L, Nordmann P, Carta C, Carattoli A. Complete sequencing of an IncH plasmid carrying the blaNDM-1, blaCTX-M-15 and qnrB1 genes. J. Antimicrob. Chemother. 67(7), 1645–1650 (2012).
  • Kaase M, Nordmann P, Wichelhaus TA, Gatermann SG, Bonnin RA, Poirel L. NDM-2 carbapenemase in Acinetobacter baumannii from Egypt. J. Antimicrob. Chemother. 66(6), 1260–1262 (2011).
  • Nordmann P, Boulanger AE, Poirel L. NDM-4 metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli. Antimicrob. Agents Chemother. 56(4), 2184–2186 (2012).
  • Hornsey M, Phee L, Wareham DW. A novel variant, NDM-5, of the New Delhi metallo-beta-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom. Antimicrob. Agents Chemother. 55(12), 5952–5954 (2011).
  • Espedido BA, Steen JA, Ziochos H et al. Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution. PloS ONE 8(3), e59920 (2013).
  • Tada T, Miyoshi-Akiyama T, Dahal RK et al. NDM-8 metallo-beta-lactamase in a multidrug-resistant Escherichia coli strain isolated in Nepal. Antimicrob. Agents Chemother. 57(5), 2394–2396 (2013).

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