261
Views
14
CrossRef citations to date
0
Altmetric
Reviews

State of the art syphilis diagnostics: rapid point-of-care tests

, &

References

  • Schaudinn F, Hoffmann P. Vorlaufiger Bericht uber das Vorkommen von Spirochaten in syphilitischen Krankheitprodukten und bei Papillomen. Arb. Gesundheitsamt. Berlin 22, 527–534 (1904–1905).
  • Newman L, Kamb M, Hawkes S et al. Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data. PLoS Med. 10(2), e1001396 (2013).
  • Gloyd S, Chai S, Mercer MA. Antenatal syphilis in sub-Saharan Africa: missed opportunities for mortality reduction. Health Policy Plan. 16(1), 29–34 (2001).
  • Watson-Jones D, Changalucha J, Gumodoka B et al. Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy. J. Infect. Dis. 186, 940–947 (2002).
  • Health Protection Agency. Syphilis and Lymphogranuloma Venereum: Resurgent Sexually Transmitted Infections in the UK: 2009 report. Public Health England, London, UK (2009).
  • Chen ZQ, Zhang GC, Gong XD et al. Syphilis in China: results of a national surveillance programme. Lancet 369,132–138 (2007).
  • Yang L. Annual STD surveillance for Guangdong province, China. Presented at: Guangdong Annual STI Control Conference. Huidong, China, 15–16 April 2010.
  • Li Y, Detels R, Lin P et al. Prevalence of HIV and STIs and associated risk factors among female sex workers in Guangdong province, China. J. Acquir. Immune Defic. Syndr. 53( Suppl. 1), S48–S53 (2010).
  • Feng TJ, Liu XL, Cai YM et al. Prevalence of syphilis and human immunodeficiency virus infections among men who have sex with men in Shenzen, China: 2005 to 2007. Sex. Transm. Dis. 35, 1022–1024 (2008).
  • Hutchinson CM, Rompalo AM, Reichart CA, Hook EW. Characteristics of patients with syphilis attending Baltimore STD clinics. Arch. Intern. Med. 151, 511–516 (1991).
  • Mwapasa V, Rogerson SJ, Kwelk JJ et al. Maternal syphilis infection is associated with increased risk of mother-to-child transmission of HIV in Malawi. AIDS 20, 1869–1877 (2006).
  • Chibwesh CJ, Giganti MJ, Putta N et al. Optimal time on HAART for prevention of mother-to-child transmission of HIV. J. Acquir. Immune Defic. Syndr. 58, 224–228 (2011).
  • Temmerman M, Ali FM, Ndinya-Achola J, Moses S, Plummer FA, Piot P. Rapid increase of both HIV-1 infection and syphilis among pregnant women in Nairobi, Kenya. AIDS 6, 1181–1185 (1992).
  • Kalichman S, Pellowski J, Turner C. Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: systematic review with implications for using HIV treatments for prevention. Sex. Transm. Infect. 87, 183–190 (2011).
  • Larsen SA, Steiner BM, Rudolph AH. Laboratory diagnosis and interpretation of tests for syphilis. Clin. Microbiol. Rev. 8(1), 1–21 (1995).
  • Gayet-Ageron A, Lautenschalger S, Ninet B, Perneger TV, Combescure C. Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis. Sex. Transm. Infect. 18(3), 251–256 (2013).
  • Jafari Y, Peeling RW, Shivkumar S, Claessens C, Joseph L, Pant Pai N. Are Treponema pallidum specific rapid and point-of-care tests for syphilis accurate enough for screening in resource limited settings? Evidence from a meta-analysis. PLoS ONE 8(2), e54695 (2013).
  • Peeling RW, Ye H. Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview. Bull. World Health Organ. 82(6), 439–446 (2004).
  • Creegan L, Bauer HM, Samuel MC et al. An evaluation of the relative sensitivities of the venereal disease research laboratory test and the Treponema pallidum particle agglutination test among patients diagnosed with primary syphilis. Sex. Transm. Dis. 34, 1016–1018 (2007).
  • Kingston M, French P, Goh B et al. UK National guidelines on the management of syphilis 2008. Int. J. STD AIDS 19, 729–740 (2008).
  • Marseille E, Kahn JG, Pitter C et al. The cost effectiveness of home-based provision of antiretroviral therapy in rural Uganda. Appl. Health Econ. Health Policy 7, 229–243 (2009).
  • Terris-Prestholt F, Watson-Jones D, Mugeye K et al. Is antenatal syphilis screening still cost effective in sub-Saharan Africa. Sex. Transm. Infect. 79, 375–381 (2003).
  • Watson-Jones D, Gumodoka B, Weiss H et al. Syphilis in Pregnancy in Tanzania. II.The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes. J. Infect. Dis. 186, 948–957 (2002).
  • Schmid GP, Stoner BP, Hawkes S, Broutet N. The need and plan for global elimination of congenital syphilis. Sex. Transm. Dis. 34 (7), S5–S10 (2007).
  • Gift TL, Pate MS, Hook EW 3rd, Kassler WJ. The rapid test paradox: when fewer cases detected lead to more cases treated: a decision analysis of tests for Chlamydia trachomatis. Sex. Transm. Dis. 26, 232–240 (1999).
  • Kettler H, White K, Hawkes S. Mapping the landscape of diagnostics for sexually transmitted infections. WHO/TDR, Geneva, Switzerland (2004).
  • Peeling RW, Mabey D. Point-of-care tests for diagnosing infections in the developing world. Clin. Microbiol. Infect. 16, 1062–1069 (2010).
  • Mabey D, Peeling RW, Ballard R et al. Prospective, multi-centre clinic-based evaluation of four rapid diagnostic tests for syphilis. Sex Transm Infect 82(5) v13–v16 (2006).
  • Tucker JD, Bu J, Brown LB, Yin YP, Chen XS, Cohen MS. Accelerating worldwide syphilis screening through rapid testing: a systematic review. Lancet Infect. Dis. 10, 381–386 (2010).
  • Benzaken AS, Sabido M, Galban EG et al. Field evaluation of the performance and testing costs of a rapid point-of-care test for syphilis in a red-light district of Manaus, Brazil. Sex. Transm. Infect. 84, 297–302 (2008).
  • Tinajeros F, Grossman D, Richmond K et al. Diagnostic accuracy of a point-of-care syphilis test when used among pregnant women in Bolivia. Sex. Transm. Infect. 82(Suppl 5), v17–v21 (2006).
  • Gianino MM, Dal Conte I, Sciole K et al. Performance and costs of a rapid syphilis test in an urban population at high risk for sexually transmitted infections. J. Prev. Med. Hyg. 48, 118–122 (2007).
  • Nessa K, Alam A, Chawdhury FA et al. Field evaluation of simple rapid tests in the diagnosis of syphilis. Int. J. STD AIDS 19, 316–320 (2008).
  • Villazon-Vargas N, Conde-Glez CJ, Juarez-Figueroa L, Uribe-Salas F. Evaluation of a rapid diagnostic test to assess the prevalence of maternal syphilis in Bolivia. Rev. Med. Chil. 137, 515–521 (2009).
  • Hernandez-Trejo M, Hernandez-Prado B, Uribe-Salas F, Juarez-Figueroa L, Conde-Gonzalez CJ. Maternal and congenital syphilis in two Mexican hospitals: evaluation of a rapid diagnostic test. Rev. Invest. Clin. 58, 119–125 (2006).
  • West B, Walraven G, Morison L, Brouwers J, Bailey R. Performance of the rapid plasma regain and the rapid syphilis screening tests in the diagnosis of syphilis in field conditions in rural Africa. Sex. Transm. Infect. 78(4), 282–285 (2002).
  • Montoya PJ, Lukehart SA, Brentlinger PE et al. Comparison of the diagnostic accuracy of a rapid immunochromatographic test and the rapid plasma regain test for antenatal syphilis screening in Mozambique. Bull. World Health Organ. 84(2), 97–104 (2006).
  • Hawkes SJ, Gomez GB, Broutet N. Early antenatal care: does it make a difference to outcomes of pregnancy associated with syphilis? A systematic review and meta-analysis. PLoS ONE 8(2), e56713 (2013).
  • Schmid G. Economic and programmatic aspects of congenital syphilis prevention. Bull. World Health Organ. 82(6), 402–409 (2004).
  • Yang LG, Tucker JD, Wang C et al. Syphilis test availability and uptake at medical facilities in southern China. Bull. World Health Organ. 89, 798–805 (2011).
  • Hawkes S, Matin N, Broutet N, Low N. Effectiveness of interventions to improve screening for syphilis in pregnancy: a systematic review and meta-analysis. Lancet Infect. Dis. 11, 684–691 (2011).
  • Mabey DC, Sollis KA, Kelly HA et al. Point-of-care tests to strengthen health systems and save newborn lives: the case of syphilis. PLoS Med. 9(6), e1001233 (2012).
  • Mitchell KM, Cox AP, Mabey D, Tucker JD, Peeling RW, Vickerman P. The impact of syphilis screening among female sex workers in China: a modelling study. PLoS ONE 8(1), e55622. (2013).
  • Benzaken AS, Bazzo ML, Galban E et al. External quality assurance with dried tube specimens (DTS) for point of care syphilis and HIV tests: experience in an indigenous populations screening programme in the Brazilian Amazon. Sex. Transm. Infect. doi:10.1136/sextrans-2013-051181 (2013) ( Epub ahead of print).
  • Smit PW, van der Vlis T, Mabey D et al. The development and validation of dried blood spots for external quality assurance of syphilis serology. BMC Infect. Dis. 13, 102 (2013).
  • Bronzan RN, Mwesigwa-Kayongo DC, Narkunas D et al. On-site rapid antenatal syphilis screening with an immunochromatographic strip improves case detection and treatment in rural South African clinics. Sex. Transm. Dis. 34(7), S55–S60 (2007).
  • Castro AR, Esfandiari J, Kumar S et al. Novel point-of-care test for simultaneous detection of nontreponemal and treponemal antibodies in patients with syphilis. J. Clin. Microbiol. 48 (12), 4615–4619 (2010).
  • Yin YP, Chen XS, Wei WH et al. A dual point-of-care test shows good performance in simultaneously detecting nontreponemal and treponemal antibodies in patients with syphilis- A multi-site evaluation study in China. Clin. Infect. Dis. 56, 659–665 (2013).
  • Strasser S, Bitarakwate E, Gill M et al. Introduction of rapid syphilis testing within prevention of mother-to-child transmission of HIV programs in Uganda and Zambia: a field acceptability and feasibility study. J. Acquir. Immune Defic. Syndr. 61(3), e40–e46 (2012).
  • Chin CD, Lakasanasopin L, Cheung YK et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nat. Med. 17(8), 1015–1019 (2011).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.