Single-dose azithromycin for the treatment of children with acute otitis media

References

• Klein JO. Otitis media. Clin. Infect. Dis. 19, 823–833 (1994).
   PubMed Web of Science ®Google Scholar
• Schappert SM. Office visits for otitis media: United States, 1975–90. Adv. Data 214, 1–19 (1992).
   Google Scholar
• Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective, cohort study. J. Infect. Dis. 160, 83–94 (1989).
   PubMed Web of Science ®Google Scholar
• Shireman TI, Kelsey KA. Prescribing patterns and retreatment rates in patients with otitis media. Clin. Drug Invest. 22, 303–311 (2002).
   Web of Science ®Google Scholar
• Block SL, Hedrick J, Tyler RD, Smith RA, Harrison CJ. Microbiology of acute otitis media recently treated with aminopenicillins. Pediatr. Infect. Dis. J. 20, 1017–1021 (2001).
   PubMed Web of Science ®Google Scholar
• Arguedas A, Loaiza C, Perez A et al. Microbiology of acute otitis media in Costa Rican children. Pediatr. Infect. Dis. J. 17, 680–689 (1998).
   PubMed Web of Science ®Google Scholar
• American Academy of Pediatrics, American Academy of Family Physicians, subcommittee on management of acute otitis media. Diagnosis and management of acute otitis media. Pediatrics 113, 1451–1465 (2004).
   PubMed Web of Science ®Google Scholar
• Piglansky L, Leibovitz E, Raiz S et al. Bacteriologic and clinical efficacy of high dose amoxicillin for therapy of acute otitis media in children. Pediatr. Infect. Dis. J. 22, 405–413 (2003).
   PubMed Web of Science ®Google Scholar
• Dowell SF, Marcy MS, Phillips WR, Gerber MA, Schwartz B. Otitis media – principles of judicious use of antimicrobial agents. Pediatrics 101, 165–171 (1998).
   Web of Science ®Google Scholar
• Roger G, Carles P, Pangon B et al. Management of acute otitis media caused by resistant pneumococci in infants. Pediatr. Infect. Dis. J. 17, 631–638 (1998).
   PubMed Web of Science ®Google Scholar
• Dagan R, Leibovitz E. Bacterial eradication in the treatment of otitis media. Lancet Infect. Dis. 2, 593–604 (2002).
   PubMed Web of Science ®Google Scholar
• Dowell SF, Butler JC, Giebink GS et al. Acute otitis media: management and surveillance in an era of pneumococcal resistance – a report from the drug-resistant Streptococcus pneumoniae Therapeutic Working Group. Pediatr. Infect. Dis. J. 18, 1–9 (1999).
   PubMed Web of Science ®Google Scholar
• Girard AD, Girard D, English AR et al. Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution. Antimicrob. Agents Chemother. 32, 1948–1954 (1987).
   Google Scholar
• Thornsberry C, Ogilvie PT, Holley HP Jr, Sahm DF. Survey of susceptibilities of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates to 26 antimicrobial agents: a prospective US study. Antimicrob. Agents Chemother. 43, 2612–2623 (1999).
   PubMed Web of Science ®Google Scholar
• Foulds G, Shepard RM, Johnson RB. The pharmacokinetics of azithromycin in human serum and tissues. J. Antimicrob. Chemother. 25(Suppl. A), 73–82 (1990).
   PubMed Web of Science ®Google Scholar
• Foulds G, Johnson RB. Selection of dose regimens of azithromycin. J. Antimicrob. Chemother. 31(Suppl. E), 39–50 (1993).
   PubMedGoogle Scholar
• Rothermel CD. Single-dose azithromycin for acute otitis media: a pharmacokinetic/pharmacodynamic rationale. Curr. Ther. Res. 64(Suppl. A), A4–A15 (2003).
   PubMedGoogle Scholar
• Gordon EM, Blumer JL. Rationale for single and high dose treatment regimens with azithromycin. Pediatr. Infect. Dis. J. 23, S102–S107 (2004).
   Google Scholar
• Girard AD, Cimochowski CR, Faiella JA. The comparative activity of azithromycin, macrolides and amoxicillin against streptococci in experimental infections. J. Antimicrob. Chemother. 31(Suppl. E), 29–37 (1993).
   PubMedGoogle Scholar
• Girard D, Finegan SM, Cimochowski CR et al. Accelerated dosing of azithromycin in preclinical infection models. 102nd General Meeting of the American Society for Microbiology. UT, USA (2002).
   Google Scholar
• Babl FE, Pelton SI, Li Z. Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo. Antimicrob. Agents Chemother. 46, 2194–2199 (2002).
   PubMed Web of Science ®Google Scholar
• Pukander J, Rautianen M. Penetration of azithromycin into middle ear effusions in acute and secretory otitis media in children. J. Antimicrob. Chemother. 37(Suppl. C), 53–61 (1996).
   PubMed Web of Science ®Google Scholar
• Dagan R, Leibovitz E, Fliss DM et al. Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. Antimicrob. Agents Chemother. 44, 43–50 (2000).
   PubMed Web of Science ®Google Scholar
• Scaglioni F, Demartini G, Dugnani S, Arcidiacono MM, Pintucci JP, Fraschini F. Interpretation of middle-ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. J. Clin. Pharmacol. 47, 167–271 (1999).
   Web of Science ®Google Scholar
• Arguedas A, Dagan R, Soley C et al. Microbiology of otitis media in Costa Rican children, 1999 through 2001. Pediatr. Infect. Dis. J. 22, 1063–1068 (2003).
   PubMed Web of Science ®Google Scholar
• Jacobs MR. Increasing antibiotic resistance among otitis media pathogens and their susceptibility to oral agents based on pharmacodynamic parameters. Pediatr. Infect. Dis. J. 19, S47–S56 (2000).
   PubMed Web of Science ®Google Scholar
• Hyde TB, Gey K, Stephens DS et al. Macrolide resistance among invasive Streptococcus pneumoniae isolates. J. Am. Med. Assoc. 286, 1857–1862 (2001).
   PubMed Web of Science ®Google Scholar
• Mason EO, Wald ER, Bradley JS et al. Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes. Pediatr. Infect. Dis. J. 22, 623–627 (2003).
   PubMed Web of Science ®Google Scholar
• Black S, Shinefield H, Baxter R et al. Postlicensure surveillance of pneumococcal invasive disease after use of heptavalent pneumococcal conjugate vaccine in northern California Kaiser Permanente. Pediatr. Infect. Dis. J. 23, 485–489 (2004).
   PubMed Web of Science ®Google Scholar
• Doern GV, Richter SS, Miller A et al. Antimicrobial resistance among Streptococcus pneumoniae in the United States: have we begun to turn the corner on resistance to certain antimicrobial classes? Clin. Infect. Dis. J. 41, 139–148 (2005).
   PubMed Web of Science ®Google Scholar
• Segal N, Givon-Lavi N, Leibovitz E, Yagupsky P, Leiberman A, Dagan R. Acute otitis media caused by Streptococcus pyogenes in children. Clin. Infect. Dis. J. 41, 35–41 (2005).
   PubMed Web of Science ®Google Scholar
• Reinert R, Lütticken R, Bryskier A, Al-Lahham A. Macrolide-resistant Streptococcus pneumoniae and Streptococcus pyogenes in the pediatric population in Germany during 2000–2001. Antimicrob. Agents Chemother. 47, 489–493 (2003).
   Google Scholar
• Perez-Trallero E, Fernandez-Mazarrasa C, Garcia-Rey C et al. Antimicrobial susceptibilities of 1,684 Streptococcus pneumoniae and 2,039 Streptococcus pyogenes isolates and their ecological relationships: results of a 1 year (1998–1999) multicenter suveillance study in Spain. Antimicrob. Agents Chemother. 45, 3334–3340 (2001).
   PubMed Web of Science ®Google Scholar
• Arguedas A, Loaiza C, Herrera ML, Mohs E. Comparative trial of three days azithromycin versus ten days of amoxicillin clavulanate potassium in the treatment of children with acute otitis media with effusion. Int. J. Antimicrob. Agents 6, 233–238 (1996).
   PubMed Web of Science ®Google Scholar
• Arguedas A, Loaiza C, Herrera ML, Mohs E. Comparative trial of three days azithromycin versus ten days clarithromycin in the treatment of children with acute otitis media with effusion. J. Chemother. 9, 44–50 (1997).
   PubMed Web of Science ®Google Scholar
• McLinn S. A multicenter, double-blind comparison of azithromycin and amoxicillin/clavulanate for the treatment of acute otitis media in children. Pediatr. Infect. Dis. J. 15, S20–S23 (1996).
   PubMed Web of Science ®Google Scholar
• Principi N. Multicentre comparative study of the efficacy and safety of azithromycin compared with amoxicillin/clavulanic acid in the treatment of paediatric patients with otitis media. Eur. J. Clin. Microbiol. Infect. Dis. 14, 669–676 (1995).
   PubMed Web of Science ®Google Scholar
• Khurana CM. A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school. Pediatr. Infect. Dis. J. 15(9 Suppl.), S24–S29 (1996).
   Google Scholar
• Arguedas A, Loaiza C, Perez A, Gutierrez A, Herrera ML, Rothermel CD. A pilot study of single-dose azithromycin versus 3-day azithromycin or single-dose ceftriaxone for uncomplicated acute otitis media in children. Curr. Ther. Res. 64(Suppl. A), A16–A29 (2003).
   PubMedGoogle Scholar
• Dunne MW, Khurana C, Arguedas A et al. Efficacy of single dose azithromycin in the treatment of acute otitis media in children receiving a baseline tympanocentesis. Antimicrob. Agents Chemother. 47, 2663–2665 (2003).
   PubMed Web of Science ®Google Scholar
• Block, SL, Arrieta A, Seibel M, McLinn S, Eppes S, Murphy MJ. Single-dose (30 mg/kg) azithromycin compared with 10-day amoxicillin/clavulanate for the treatment of uncomplicated acute otitis media. Curr. Ther. Res. 64(Suppl. A), A30–A42 (2003).
   Google Scholar
• Arguedas A, Emparanza P, Schwartz R et al. A randomized, multicenter, double-blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media. Pedriatr. Infect. Dis. J. 24, 153–161 (2005).
   PubMed Web of Science ®Google Scholar
• US Department of Health and Human Services. Guidance for Industry, Acute Otitis Media – Developing Antimicrobial Drugs for Treatment. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), WA, USA (1998).
   Google Scholar
• Arguedas A, Jorgensen D, Soley C, Dunne M. Single dose (SD) azithromycin (AZM) for treatment (TX) of acute otitis media (AOM) in children < 2 years of age. 43rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy. IL, USA (2003).
   Google Scholar
• Arrieta A, Arguedas A, Fernandez P et al. High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. Antimicrob. Agents Chemother. 47, 3179–3186 (2003).
   PubMed Web of Science ®Google Scholar
• Quach C, Moore DL, Collet JP, Lelorier J. Antibiotic utilization and outcomes in the treatment of recurrent acute otitis media in children. 43rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy. IL, USA (2003).
   Google Scholar
• Leibovitz E, Jacobs M, Dagan R. Haemophilus influenzae: a significant pathogen in acute otitis media. Pediatr. Infect. Dis. J. 23(12), 1142–1152 (2004).
   PubMed Web of Science ®Google Scholar
• Dagan R, Johnson C, Mclinn S et al. Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media. Pediatr. Infect. Dis. J. 19, 95–104 (2000).
   PubMed Web of Science ®Google Scholar
• Hoberman A, Dagan R, Leibovitz E et al. Large dose amoxicillin/clavulanate, compared with azithromycin, for the treatment of bacterial acute otitis media in children. Pediatr. Infect. Dis. J. 24, 525–532 (2005).
   PubMed Web of Science ®Google Scholar
• Cohen R, Reinert P, De La Rocque R et al. Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. Pediatr. Infect. Dis. J. 21, 297–303 (2002).
   PubMed Web of Science ®Google Scholar