419
Views
6
CrossRef citations to date
0
Altmetric
Perspectives

Phosphatase Wip1 as a new therapeutic target for intestinal ischemia-reperfusion injury

, , &

References

  • Hart ML, Jacobi B, Schittenhelm J, et al. Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury. J Immunol 2009;182(7):3965-8
  • Eltzschig HK, Eckle T. Ischemia and reperfusion–from mechanism to translation. Nat Med 2011;17(11):1391-401
  • Kubes P, Hunter J, Granger DN. Ischemia/reperfusion-induced feline intestinal dysfunction: importance of granulocyte recruitment. Gastroenterology 1992;103(3):807-12
  • Tan Z, Jiang R, Wang X, et al. RORgammat+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. Journal of molecular cell biology 2013;5(2):143-6
  • Mantovani A, Cassatella MA, Costantini C, Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nature reviews Immunology 2011;11(8):519-31
  • Kohler D, Straub A, Weissmuller T, et al. Phosphorylation of vasodilator-stimulated phosphoprotein prevents platelet-neutrophil complex formation and dampens myocardial ischemia-reperfusion injury. Circulation 2011;123(22):2579-90
  • Williams IR, Parkos CA. Colonic neutrophils in inflammatory bowel disease: double-edged swords of the innate immune system with protective and destructive capacity. Gastroenterology 2007;133(6):2049-52
  • Kuhl AA, Kakirman H, Janotta M, et al. Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils. Gastroenterology 2007;133(6):1882-92
  • Lu YZ, Wu CC, Huang YC, et al. Neutrophil priming by hypoxic preconditioning protects against epithelial barrier damage and enteric bacterial translocation in intestinal ischemia/reperfusion. Laboratory investigation; a journal of technical methods and pathology 2012;92(5):783-96
  • Fiscella M, Zhang H, Fan S, et al. Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc Natl Acad Sci USA 1997;94(12):6048-53
  • Salminen A, Kaarniranta K. Control of p53 and NF-kappaB signaling by WIP1 and MIF: role in cellular senescence and organismal aging. Cell Signal 2011;23(5):747-52
  • Zhu Y, Demidov ON, Goh AM, et al. Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J Clin Invest 2014;124(7):3263-73
  • Liu G, Hu X, Sun B, et al. Phosphatase Wip1 negatively regulates neutrophil development through p38 MAPK-STAT1. Blood 2013;121(3):519-29
  • Sun B, Hu X, Liu G, et al. Phosphatase Wip1 negatively regulates neutrophil migration and inflammation. J Immunol 2014;192(3):1184-95
  • Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006;124(4):837-48
  • Souza DG, Vieira AT, Soares AC, et al. The essential role of the intestinal microbiota in facilitating acute inflammatory responses. J Immunol 2004;173(6):4137-46
  • Shifflett DE, Bottone FG Jr, Young KM, et al. Neutrophils augment recovery of porcine ischemia-injured ileal mucosa by an IL-1beta- and COX-2-dependent mechanism. Am J Physiol Gastrointest Liver Physiol 2004;287(1):G50-7
  • Kreisel D, Sugimoto S, Tietjens J, et al. Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis. J Clin Invest 2011;121(1):265-76
  • Farrar CA, Asgari E, Schwaeble WJ, Sacks SH. Which pathways trigger the role of complement in ischaemia/reperfusion injury? Frontiers in immunology 2012;3:341
  • Matsuo Y, Onodera H, Shiga Y, et al. Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletion. Stroke 1994;25(7):1469-75
  • Sisley AC, Desai T, Harig JM, Gewertz BL. Neutrophil depletion attenuates human intestinal reperfusion injury. J Surg Res 1994;57(1):192-6
  • Martinez-Mier G, Toledo-Pereyra LH, McDuffie JE, et al. Neutrophil depletion and chemokine response after liver ischemia and reperfusion. J Invest Surg 2001;14(2):99-107
  • Sarma JV, Ward PA. New developments in C5a receptor signaling. Cell health and cytoskeleton 2012;4:73-82
  • Wu MC, Brennan FH, Lynch JP, et al. The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization. Proc Natl Acad Sci U S A 2013;110(23):9439-44
  • Diepenhorst GM, van Gulik TM, Hack CE. Complement-mediated ischemia-reperfusion injury: lessons learned from animal and clinical studies. Ann Surg 2009;249(6):889-99
  • Shernan SK, Fitch JC, Nussmeier NA, et al. Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypass. Ann Thorac Surg 2004;77(3):942-9. discussion 949-950
  • Verrier ED, Shernan SK, Taylor KM, et al. Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial. JAMA 2004;291(19):2319-27
  • Shen X, Du J, Guan W, Zhao Y. The balance of intestinal Foxp3(+) regulatory T cells and Th17 cells and its biological significance. Expert Rev Clin Immunol 2014;10(3):353-62
  • Shichita T, Sugiyama Y, Ooboshi H, et al. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med 2009;15(8):46-950
  • Lee HT, Kim M, Kim JY, et al. Critical role of interleukin-17A in murine intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol 2013;304(1):G12-25
  • Holtta V, Klemetti P, Salo HM, et al. Interleukin-17 immunity in pediatric Crohn disease and ulcerative colitis. J Pediatr Gastroenterol Nutr 2013;57(3):287-92
  • Garrido-Mesa N, Algieri F, Rodriguez Nogales A, Galvez J. Functional plasticity of Th17 cells: implications in gastrointestinal tract function. Int Rev Immunol 2013;32(5-6):493-510
  • Deshmukh HS, Liu Y, Menkiti OR, et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat Med 2014;20(5):524-30
  • Buss MC, Remke M, Lee J, et al. The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants. Oncogene 2014;17. [Epub ahead of print]
  • Zhu YH, Bulavin DV. Wip1-dependent signaling pathways in health and diseases. Prog Mol Biol Transl Sci 2012;106:307-25
  • Lowe J, Cha H, Lee MO, et al. Regulation of the Wip1 phosphatase and its effects on the stress response. Front Biosci (Landmark Ed) 2012;17:1480-98
  • Echemendia-Blanco D, Van Driessche E, Ncube I, et al. Stability, subunit interactions and carbohydrate-binding of the seed lectin from Pterocarpus angolensis. Protein Pept Lett 2009;16(9):1120-34
  • Oshima T, Sasaki M, Kataoka H, et al. Wip1 protects hydrogen peroxide-induced colonic epithelial barrier dysfunction. Cell Mol Life Sci 2007;64(23):3139-47
  • Altshuler AE, Richter MD, Modestino AE, et al. Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. Physiological reports 2013;1(5):e00109
  • Lapchak PH, Ioannou A, Rani P, et al. The role of platelet factor 4 in local and remote tissue damage in a mouse model of mesenteric ischemia/reperfusion injury. PLoS One 2012;7(7):e39934
  • Schmeling DJ, Caty MG, Oldham KT, et al. Evidence for neutrophil-related acute lung injury after intestinal ischemia-reperfusion. Surgery 1989;106(2):195-201. discussion 201-192

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.