The role of sports and exercise in allergic disease: drawbacks and benefits

References

• Carlsen K-H, Anderson S, Bjermer L, et al. Exercise-induced asthma, respiratory and allergic disorders in elite athletes: epidemiology, mechanisms and diagnosis: part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA2LEN. Allergy 2008;63(4):387-403
   PubMed Web of Science ®Google Scholar
• Helenius I, Tikkanen H, Haahtela T. Occurrence of exercise induced bronchospasm in elite runners: dependence on atopy and exposure to cold air and pollen. Br J Sports Med 1998;32:125-9
   PubMed Web of Science ®Google Scholar
• Bougault V, Turmel J, St-Laurent J, et al. Asthma, airway inflammation and epithelial damage in swimmers and cold-air athletes. Eur Respir J 2009;33:740-6
   PubMed Web of Science ®Google Scholar
• Bonini S, Bonini M, Bousquet J, et al. Rhinitis and asthma in athletes: an ARIA document in collaboration with GA2LEN. Allergy 2006;61(6):681-92
   PubMed Web of Science ®Google Scholar
• Dijkstra HP, Robson-Ansley P. The prevalence and current opinion of treatment of allergic rhinitis in elite athletes. Curr Opin Allergy Clin Immunol 2011;11(2):103-8
   PubMed Web of Science ®Google Scholar
• Anderson SD, Daviskas E. The mechanism of exercise-induced asthma is. J Allergy Clin Immunol 2000;106(3):453-9
   PubMed Web of Science ®Google Scholar
• Carlsen KH. Sports in extreme conditions: the impact of exercise in cold temperatures on asthma and bronchial hyper-responsiveness in athletes. Br J Sports Med 2012;46(11):796-9
   PubMed Web of Science ®Google Scholar
• Warburton DE, Nicol CW, Bredin SS. Health benefits of physical activity: the evidence. CMAJ 2006;174(6):801-9
   PubMed Web of Science ®Google Scholar
• Carson KV, Chandratilleke MG, Picot J, et al. Physical training for asthma. Cochrane Database Syst Rev 2013;9:CD001116
   PubMedGoogle Scholar
• Schwartz LB, Delgado L, Craig T, et al. Exercise-induced hypersensitivity syndromes in recreational and competitive athletes: a PRACTALL consensus report (what the general practitioner should know about sports and allergy). Allergy 2008;63(8):953-61
   PubMed Web of Science ®Google Scholar
• Haahtela T, Malmberg P, Moreira A. Mechanisms of asthma in Olympic athletes–practical implications. Allergy 2008;63(6):685-94
   PubMed Web of Science ®Google Scholar
• Hull J, Ansley L, Garrod R, Dickinson J. Exercise-Induced Bronchoconstriction in Athletes-Should We Screen? Med Sci Sports Exerc 2007;39(12):2117-24
   PubMed Web of Science ®Google Scholar
• Haatela T, Larsson K, Bonini S. Epidemiology of asthma, allergy and bronchial hyperresponsiveness in sports. Eur Respir Mon 2005;33:1-4
   Google Scholar
• Helenius I, Haahtela T. Allergy and asthma in elite summer sport athletes. J Allergy Clin Immunol 2000;106(3):444-52
   PubMed Web of Science ®Google Scholar
• Larsson K, Ohlsén P, Larsson L, et al. High prevalence of asthma in cross-country skiers. Br Med J 1993;307:1326-9
   PubMed Web of Science ®Google Scholar
• Helenius I, Tikkanen H, Sarna S, Haahtela T. Asthma and increased bronchial responsiveness in elite athletes: atopy and sport event as risk factors. J Allergy Clin Immunol 1998;101(5):646-52
   PubMed Web of Science ®Google Scholar
• Fitch KD. An overview of asthma and airway hyper-responsiveness in Olympic athletes. Br J Sports Med 2012;46(6):413-16
   PubMed Web of Science ®Google Scholar
• Carbonnelle S, Francaux M, Doyle I, et al. Changes in serum pneumoproteins caused by short-term exposures to nitrogen trichloride in indoor chlorinated swimming pools. Biomarkers 2002;7:464-78
   PubMed Web of Science ®Google Scholar
• Kanazawa H. VEGF, angiopoietin-1 and -2 in bronchial asthma: new molecular targets in airway angiogenesis and microvascular remodeling. Recent Pat Inflamm Allergy Drug Discov 2007;1(1):1-8
   PubMedGoogle Scholar
• Stang J, Couto M, Carlsen KH, Stensrud T. Increased bronchial parasympathetic tone in elite cross-country and biathlon skiers: a randomised crossover study. Br J Sports Med 2014;10.1136/bjsports-2014-094053. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Filipe JA, Falcao-Reis F, Castro-Correia J, Barros H. Assessment of autonomic function in high level athletes by pupillometry. Auton Neurosci 2003;104(1):66-72
   PubMed Web of Science ®Google Scholar
• Kaltsatou A, Kouidi E, Fotiou D, Deligiannis P. The use of pupillometry in the assessment of cardiac autonomic function in elite different type trained athletes. Eur J Appl Physiol 2011;111(9):2079-87
   PubMed Web of Science ®Google Scholar
• Ramalho R, Pirraco A, Soares R, et al. Neurogenic inflammation in the airways of elite swimmers. J Sports Med Phys Fitness 2014;54(2):252-3
   PubMed Web of Science ®Google Scholar
• Kanazawa H, Asai K, Hirata K, Yoshikawa J. Vascular involvement in exercise-induced airway narrowing in patients with bronchial asthma. Chest 2002;122(1):166-70
   PubMed Web of Science ®Google Scholar
• Moreira A, Palmares C, Lopes C, Delgado L. Airway vascular damage in elite swimmers. Respir Med 2011;105(11):1761-5
   PubMed Web of Science ®Google Scholar
• Bonsignore MR, Morici G, Riccobono L, et al. Airway cells after swimming outdoors or in the sea in nonasthmatic athletes. Med Sci Sports Exerc 2003;35(7):1146-52
   PubMed Web of Science ®Google Scholar
• Carlsen K-H. The breathless adolescent asthmatic athlete. Eur Resp J 2011;38:713-20
   PubMed Web of Science ®Google Scholar
• Moreira A, Delgado L, Carlsen KH. Exercise-induced asthma: why is it so frequent in Olympic athletes? Expert Rev Respir Med 2011;5(1):1-3
   PubMed Web of Science ®Google Scholar
• Butler CA, Heaney LG. Neurogenic inflammation and asthma. Inflamm Allergy Drug Targets 2007;6(2):127-32
   PubMedGoogle Scholar
• Ramalho R, Almeida J, Beltrao M, et al. Neurogenic inflammation in allergen-challenged obese mice: A missing link in the obesity-asthma association? Exp Lung Res 2012;38(6):316-24
   PubMed Web of Science ®Google Scholar
• Ramalho R, Almeida J, Fernandes R, et al. Neurokinin-1 receptor, a new modulator of lymphangiogenesis in obese-asthma phenotype. Life Sci 2013;93(4):169-77
   PubMed Web of Science ®Google Scholar
• Couto M, de Diego A, Perpina M, et al. Cough reflex testing with inhaled capsaicin and trpv1 activation in asthma and comorbid conditions. J Investig Allergol Clin Immunol 2013;23(5):289-301
   PubMed Web of Science ®Google Scholar
• Ramalho R, Soares R, Couto N, Moreira A. Tachykinin receptors antagonism for asthma: a systematic review. BMC Pulmonary Med 2011;11:41
   PubMed Web of Science ®Google Scholar
• Colsoul B, Nilius B, Vennekens R. On the putative role of transient receptor potential cation channels in asthma. Clin Exp Allergy 2009;39:1456-66
   PubMed Web of Science ®Google Scholar
• Banner K, Igney F, Poll C. TRP channels: emerging targets for respiratory disease. Pharmacol Ther 2011;130(3):371-84
   PubMed Web of Science ®Google Scholar
• Hallstrand T, Debley J, Farin F, Henderson WJr. Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction. J Allergy Clin Immunol 2007;119(5):1092-8
   PubMed Web of Science ®Google Scholar
• Tremblay MS, Colley RC, Saunders TJ, et al. Physiological and health implications of a sedentary lifestyle. Appl Physiol Nutr Metab 2010;35(6):725-40
   PubMed Web of Science ®Google Scholar
• Walsh NP, Gleeson M, Shephard RJ, et al. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev 2011;17:6-63
   PubMed Web of Science ®Google Scholar
• Nieman DC, Luo B, Dreau D, et al. Immune and inflammation responses to a 3-day period of intensified running versus cycling. Brain behavior Immunity 2014;39:180-5
   PubMed Web of Science ®Google Scholar
• Cox AJ, Pyne DB, Saunders PU, et al. Cytokine responses to treadmill running in healthy and illness-prone athletes. Med Sci Sports Exerc 2007;39(11):1918-26
   PubMed Web of Science ®Google Scholar
• Teixeira AM, Rama L, Carvalho HM, et al. Changes in naive and memory T-cells in elite swimmers during a winter training season. Brain Behav Immun 2014;39:186-93
   PubMed Web of Science ®Google Scholar
• Moreira A, Delgado L, Moreira P, Haahtela T. Does exercise increase the risk of upper respiratory tract infections? Br Med Bull 2009;90:111-31
   PubMed Web of Science ®Google Scholar
• Nieman DC. Exercise, upper respiratory tract infection, and the immune system. Med Sci Sports Exerc 1994;26(2):128-39
   PubMed Web of Science ®Google Scholar
• Kurowski M, Jurczyk J, Jarzebska M, et al. Association of serum Clara cell protein CC16 with respiratory infections and immune response to respiratory pathogens in elite athletes. Respir Res 2014;15:45
   PubMed Web of Science ®Google Scholar
• Nieman DC, Henson DA, Smith LL, et al. Cytokine changes after a marathon race. J Appl Physiol 2001;91(1):109-14
   PubMed Web of Science ®Google Scholar
• Moreira A, Kekkonen RA, Delgado L, et al. Nutritional modulation of exercise-induced immunodepression in athletes: a systematic review and meta-analysis. Eur J Clin Nutr 2007;61(4):443-60
   PubMed Web of Science ®Google Scholar
• Horn PL, West NP, Pyne DB, et al. Routine exercise alters measures of immunity and the acute phase reaction. Eur J Appl Physiol 2015;115(2):407-15
   PubMed Web of Science ®Google Scholar
• Lira FS, Rosa JC, Pimentel GD, et al. Endotoxin levels correlate positively with a sedentary lifestyle and negatively with highly trained subjects. Lipids Health Dis 2010;9:82
   PubMedGoogle Scholar
• Moreira A, Kekkonen R, Korpela R, et al. Allergy in marathon runners and effect of Lactobacillus GG supplementation on allergic inflammatory markers. Respir Med 2007;101(6):1123-31
   PubMed Web of Science ®Google Scholar
• Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008;63(Suppl 86):8-160
   PubMed Web of Science ®Google Scholar
• Katelaris CH, Carrozzi FM, Burke TV, Byth K. Patterns of allergic reactivity and disease in Olympic athletes. Clin J Sport Med 2006;16(5):401-5
   PubMed Web of Science ®Google Scholar
• Diana S, André M, Luís D. Allergic Rhinitis and Sports. In: Kowalski M, editor. Allergic Rhinitis 2012. Available from: http://www.intechopen.com/books/allergic-rhinitis/allergic-rhinitis-and-sports. ISBN: 978-953-51-0288-5, InTech, DOI: 10.5772/26061
   Google Scholar
• Lancaster GI, Halson SL, Khan Q, et al. Effects of acute exhaustive exercise and chronic exercise training on type 1 and type 2 T lymphocytes. Exerc Immunol Rev 2004;10:91-106
   PubMed Web of Science ®Google Scholar
• Li J, Lu Y, Huang K, et al. Chinese response to allergy and asthma in Olympic athletes. Allergy 2008;63(8):962-8
   PubMed Web of Science ®Google Scholar
• Braat JP, Mulder PG, Fokkens WJ, et al. Intranasal cold dry air is superior to histamine challenge in determining the presence and degree of nasal hyperreactivity in nonallergic noninfectious perennial rhinitis. Am J Respir Crit Care Med 1998;157(6 Pt 1):1748-55
   PubMed Web of Science ®Google Scholar
• Koskela HO. Cold air-provoked respiratory symptoms: the mechanisms and management. Int J Circumpolar Health 2007;66(2):91-100
   PubMed Web of Science ®Google Scholar
• Alves A, Martins C, Delgado L, et al. Exercise-induced rhinitis in competitive swimmers. Am J Rhinol Allergy 2010;24(5):e114-17
   Google Scholar
• Katelaris CH, Carrozzi FM, Burke TV. Allergic rhinoconjunctivitis in elite athletes: optimal management for quality of life and performance. Sports Med 2003;33(6):401-6
   PubMed Web of Science ®Google Scholar
• Katelaris CH, Carrozzi FM, Burke TV, Byth K. Effects of intranasal budesonide on symptoms, quality of life, and performance in elite athletes with allergic rhinoconjunctivitis. Clin J Sport Med 2002;12(5):296-300
   PubMed Web of Science ®Google Scholar
• Rundell K. High levels of airborne ultrafine and fine particulate matter in indoor ice arenas. Inhal Toxicol 2003;15:237-50
   PubMed Web of Science ®Google Scholar
• Haahtela T, Malmberg P, Moreira A. Mechanisms of asthma in Olympic athletes – practical implications. Allergy 2008;63(6):685-94
   PubMed Web of Science ®Google Scholar
• Guidelines for safe recreational waters. Volume 2 – Swimming pools and similar recreational-water environments. World Health Organization hwwiwshbbe
   Google Scholar
• Centers for Disease Control and Prevention (CDC). Ocular and respiratory illness associated with an indoor swimming pool–Nebraska, 2006. MMWR Morb Mortal Wkly Rep 2007;56(36):929-32
   PubMedGoogle Scholar
• Bonetto G, Corradi M, Carraro S, et al. Longitudinal monitoring of lung injury in children after acute chlorine exposure in a swimming pool. Am J Respir Crit Care Med 2006;174(5):545-9
   PubMed Web of Science ®Google Scholar
• Drobnic F, Freixa A, Casan P, et al. Assessment of chlorine exposure in swimmers during training. Med Sci Sports Exerc 1996;28(2):271-4
   PubMed Web of Science ®Google Scholar
• Massin N, Bohadana AB, Wild P, et al. Respiratory symptoms and bronchial responsiveness in lifeguards exposed to nitrogen trichloride in indoor swimming pools. Occup Environ Med 1998;55(4):258-63
   PubMed Web of Science ®Google Scholar
• Thickett KM, McCoach JS, Gerber JM, et al. Occupational asthma caused by chloramines in indoor swimming-pool air. Eur Respir J 2002;19(5):827-32
   PubMed Web of Science ®Google Scholar
• Jacobs JH, Spaan S, van Rooy GB, et al. Exposure to trichloramine and respiratory symptoms in indoor swimming pool workers. Eur Respir J 2007;29(4):690-8
   PubMed Web of Science ®Google Scholar
• Rosenman KD, Millerick-May M, Reilly MJ, et al. Swimming facilities and work-related asthma. J Asthma 2015;52(1):52-8
   PubMed Web of Science ®Google Scholar
• Bernard A, Carbonnelle S, Michel O, et al. Lung hyperpermeability and asthma prevalence in schoolchildren: unexpected associations with the attendance at indoor chlorinated swimming pools. Occup Environ Med 2003;60(6):385-94
   PubMed Web of Science ®Google Scholar
• Bernard A, Carbonnelle S, Dumont X, Nickmilder M. Infant swimming practice, pulmonary epithelium integrity, and the risk of allergic and respiratory diseases later in childhood. Pediatrics 2007;119(6):1095-103
   PubMed Web of Science ®Google Scholar
• Nickmilder M, Bernard A. Ecological association between childhood asthma and availability of indoor chlorinated swimming pools in Europe. Occup Environ Med 2007;64(1):37-46
   PubMed Web of Science ®Google Scholar
• Schoefer Y, Zutavern A, Brockow I, et al. Health risks of early swimming pool attendance. Int J Hyg Environ Health 2008;211(3-4):367-73
   PubMed Web of Science ®Google Scholar
• Font-Ribera L, Villanueva CM, Gracia-Lavedan E, et al. Indoor swimming pool attendance and respiratory and dermal health in schoolchildren–HITEA Catalonia. Respir Med 2014;108(7):1056-9
   PubMed Web of Science ®Google Scholar
• Beggs S, Foong YC, Le HC, et al. Swimming training for asthma in children and adolescents aged 18 years and under. Paediatr Respir Rev 2013;14(2):96-7
   PubMed Web of Science ®Google Scholar
• Seys SF, Hox V, Van Gerven L, et al. Damage-associated molecular pattern and innate cytokine release in the airways of competitive swimmers. Allergy 2015;70(2):187-94
   PubMed Web of Science ®Google Scholar
• Pedersen L, Lund TK, Barnes PJ, et al. Airway responsiveness and inflammation in adolescent elite swimmers. J Allergy Clin Immunol 2008;122(2):322-7. 327 e321
   PubMed Web of Science ®Google Scholar
• Helenius I, Rytila P, Sarna S, et al. Effect of continuing or finishing high-level sports on airway inflammation, bronchial hyperresponsiveness, and asthma: a 5-year prospective follow-up study of 42 highly trained swimmers. J Allergy Clin Immunol 2002;109(6):962-8
   PubMed Web of Science ®Google Scholar
• Couto M, Andrade P, Pereira M, et al. Effect of competitive swimming on airway inflammation: a 3-yr longitudinal study. Pediatr Allergy Immunol 2014;25(2):193-5
   PubMed Web of Science ®Google Scholar
• Eichenberger PA, Diener SN, Kofmehl R, Spengler CM. Effects of exercise training on airway hyperreactivity in asthma: a systematic review and meta-analysis. Sports Med 2013;43(11):1157-70
   PubMed Web of Science ®Google Scholar
• Moreira A, Delgado L, Haahtela T, et al. Physical training does not increase allergic inflammation in asthmatic children. Eur Respir J 2008;32(6):1570-5
   PubMed Web of Science ®Google Scholar
• Fanelli A, Cabral AL, Neder JA, et al. Exercise training on disease control and quality of life in asthmatic children. Med Sci Sports Exerc 2007;39(9):1474-80
   PubMed Web of Science ®Google Scholar
• Wicher IB, Ribeiro MA, Marmo DB, et al. Effects of swimming on spirometric parameters and bronchial hyperresponsiveness in children and adolescents with moderate persistent atopic asthma. J Pediatr 2010;86(5):384-90
   Google Scholar
• Mendes FA, Almeida FM, Cukier A, et al. Effects of aerobic training on airway inflammation in asthmatic patients. Med Sci Sports Exerc 2011;43(2):197-203
   PubMed Web of Science ®Google Scholar
• Silva RA, Almeida FM, Olivo CR, et al. Exercise reverses OVA-induced inhibition of glucocorticoid receptor and increases anti-inflammatory cytokines in asthma. Scandinavian J Med Sci Sports 2015
   Google Scholar
• Turner S, Eastwood P, Cook A, Jenkins S. Improvements in symptoms and quality of life following exercise training in older adults with moderate/severe persistent asthma. Respiration 2011;81(4):302-10
   PubMed Web of Science ®Google Scholar
• Silva D, Couto M, Moreira P, et al. Physical training improves quality of life both in asthmatic children and their caregivers. Ann Allergy Asthma Immunol 2013;111(5):427-8
   PubMed Web of Science ®Google Scholar
• Mendes FA, Goncalves RC, Nunes MP, et al. Effects of aerobic training on psychosocial morbidity and symptoms in patients with asthma: a randomized clinical trial. Chest 2010;138(2):331-7
   PubMed Web of Science ®Google Scholar
• Moreira A, Bonini M, Garcia-Larsen V, et al. Weight loss interventions in asthma: EAACI evidence-based clinical practice guideline (part I). Allergy 2013;68(4):425-39
   PubMed Web of Science ®Google Scholar
• Stenius-Aarniala B, Poussa T, Kvarnstrom J, et al. Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study. BMJ 2000;320(7238):827-32
   PubMed Web of Science ®Google Scholar
• Scott HA, Gibson PG, Garg ML, et al. Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial. Clin Exp Allergy 2013;43(1):36-49
   PubMed Web of Science ®Google Scholar
• Ma J, Strub P, Xiao L, et al. Behavioral weight loss and physical activity intervention in obese adults with asthma. A randomized trial. Ann Am Thorac Soc 2015;12(1):1-11
   PubMed Web of Science ®Google Scholar
• Branca F, Nikogosian H, Lobstein T. World Health Organization. Regional Office for Europe. The challenge of obesity in the WHO European Region and the strategies for response. WHO Regional Office for Europe; Copenhagen, Denmark: 2007
   Google Scholar
• Lees C, Hopkins J. Effect of aerobic exercise on cognition, academic achievement, and psychosocial function in children: a systematic review of randomized control trials. Prev Chronic Dis 2013;10:E174
   PubMed Web of Science ®Google Scholar
• Laukkanen A, Pesola A, Havu M, et al. Relationship between habitual physical activity and gross motor skills is multifaceted in 5- to 8-year-old children. Scandinavian J Med Sci Sports 2014;24(2):e102-10
   PubMed Web of Science ®Google Scholar
• Clarke SF, Murphy EF, O’Sullivan O, et al. Exercise and associated dietary extremes impact on gut microbial diversity. Gut 2014;63(12):1913-20
   PubMed Web of Science ®Google Scholar
• Haahtela T, Holgate S, Pawankar R, et al. The biodiversity hypothesis and allergic disease: world allergy organization position statement. World Allergy Organization J 2013;6(1):3
   Google Scholar