TNF-α-induced programmed cell death in the pathogenesis of acquired aplastic anemia

References

• Rovó A, Tichelli A, Dufour C, SAA-WP EBMT. Diagnosis of acquired aplastic anemia. Bone Marrow Transplant 2013;48:162-7
   PubMed Web of Science ®Google Scholar
• Bacigalupo A, Podestà M, Mingari MC, et al. Immune suppression of hematopoiesis in aplastic anemia: activity of T-gamma lymphocytes. J Immunol 1980;125:1449-53
   PubMed Web of Science ®Google Scholar
• Zoumbos NC, Gascón P, Djeu JY, et al. Circulating activated suppressor T lymphocytes in aplastic anemia. N Engl J Med 1985;312(5):257-65
   PubMedGoogle Scholar
• Neal SY, Rodrigo TC, Phillip S. Current concepts in the pathophysiology and treatment of aplastic anemia. Blood 2006;108:2509-19
   PubMed Web of Science ®Google Scholar
• Li JP, Zheng CL, Han ZC. Abnormal immunity and stem/progenitor cells in acquired aplastic anemia. Crit Rev Oncol Hematol 2010;75:79-93
   PubMed Web of Science ®Google Scholar
• Nakao S, Feng X, Sugimori C. Immune pathophysiology of aplastic anemia. Int J Hematol 2005;82:196-200
   PubMed Web of Science ®Google Scholar
• Shuh M, Bohorquez H, Loss GEJr, et al. Tumor Necrosis Factor-α: Life and Death of Hepatocytes During Liver Ischemia/Reperfusion Injury. Ochsner J 2013;13:119-30
   PubMedGoogle Scholar
• Popa C, Netea MG, van Riel PL, et al. The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 2007;48:751-62
   PubMed Web of Science ®Google Scholar
• Hara T, Ando K, Tsurumi H, et al. Excessive production of tumor necrosis factor-alpha by bone marrow T lymphocytes is essential in causing bone marrow failure in patients with aplastic anemia. Eur J Haematol 2004;73:10-16
   PubMed Web of Science ®Google Scholar
• Dufour C, Ferretti E, Bagnasco F, et al. Changes in cytokine profile pre- and post-immunosuppression in acquired aplastic anemia. Haematologica 2009;94:1743-7
   PubMedGoogle Scholar
• Matthews GM, Newbold A, Johnstone RW. Intrinsic and extrinsic apoptotic pathway signaling as determinants of histone deacetylase inhibitor antitumor activity. Adv Cancer Res 2012;116:165-97
   PubMed Web of Science ®Google Scholar
• Muñoz-Pinedo C. Signaling pathways that regulate life and cell death: evolution of apoptosis in the context of self-defense. Adv Exp Med Biol 2012;738:124-43
   PubMed Web of Science ®Google Scholar
• Lavrik IN. Systems biology of apoptosis signaling networks. Curr Opin Biotechnol 2010;21:551-5
   PubMed Web of Science ®Google Scholar
• Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004;116:205-19
   PubMed Web of Science ®Google Scholar
• Lawen A. Apoptosis-an introduction. Bioessays 2003;25:888-96
   PubMed Web of Science ®Google Scholar
• Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007;35:495-516
   PubMed Web of Science ®Google Scholar
• Tsuda H, Ning Z, Yamaguchi Y, et al. Programmed cell death and its possible relationship with periodontal disease. J Oral Sci 2012;54:137-49
   PubMed Web of Science ®Google Scholar
• Degterev A, Huang Z, Boyce M, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005;1:112-19
   PubMed Web of Science ®Google Scholar
• Dunai Z, Bauer PI, Mihalik R. Necroptosis: biochemical, physiological and pathological aspects. Pathol Oncol Res 2011;17:791-800
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Maiuri MC, Vitale I, et al. Cell death modalities: classification and pathophysiological implications. Cell Death Differ 2007;14:1237-43
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Kroemer G. Necroptosis: a specialized pathway of programmed necrosis. Cell 2008;135:1161-3
   PubMed Web of Science ®Google Scholar
• Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 2010;22:263-8
   PubMed Web of Science ®Google Scholar
• Fink SL, Cookson BT. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun 2005;73:1907-16
   PubMed Web of Science ®Google Scholar
• Majno G, Joris L. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3-15
   PubMed Web of Science ®Google Scholar
• Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000;290:1717-21
   PubMed Web of Science ®Google Scholar
• Levin S. Apoptosis, necrosis, or oncosis: what is your diagnosis? A report from the Cell Death Nomenclature Committee of the Society of Toxicologic Pathologists. Toxicol Sci 1998;41:155-6
   PubMed Web of Science ®Google Scholar
• Cookson BT, Brennan MA. Pro-inflammatory programmed cell death. Trends Microbiol 2001;9:113-14
   PubMed Web of Science ®Google Scholar
• Halida Y, Guo XH, Aliya R. Expression of plasma TNF-α and TNF-β in different subtypes lymphoma and its significance. Zhonghua Xue Ye Xue Za Zhi 2011;32:695-7
   PubMedGoogle Scholar
• Xin L, Wang J, Zhang H, et al. Dual regulation of soluble tumor necrosis factor-alpha induced activation of human monocytic cells via modulating transmembrane TNF-alpha-mediated ’reverse signaling’. Int J Mol Med 2006;18:885-92
   PubMed Web of Science ®Google Scholar
• Peng XM, Zhou ZG, Glorioso JC, et al. Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury. Ann Neurol 2006;59:843-51
   PubMed Web of Science ®Google Scholar
• Kapadia S, Lee J, Torre-Amione G, et al. Tumor necrosis factor alpha gene and protein experission in adult feline myocardium after endotoxin administration. J Clin Invest 1995;96:1042-52
   PubMed Web of Science ®Google Scholar
• Zelová H, Hošek J. TNF-α signalling and inflammation: interactions between old acquaintances. Inflamm Res 2013;62:641-51
   PubMed Web of Science ®Google Scholar
• Dreschers S, Gille C, Haas M, et al. Infection-induced bystander-apoptosis of monocytes is TNF-alpha-mediated. PLoS One 2013;8:e53589
   Google Scholar
• Jacobsen SE, Jacobsen FW, Fahlman C, et al. TNF-alpha, the great imitator: role of p55 and p75 TNF receptors in hematopoiesis. Stem Cells 1994;12 Suppl 1:111-26
   PubMed Web of Science ®Google Scholar
• Rezzoug F, Huang Y, Tanner MK, et al. TNF-alpha is critical to facilitate hemopoietic stem cell engraftment and function. J Immunol 2008;180:49-57
   PubMed Web of Science ®Google Scholar
• Dubey S, Shukla P, Nityanand S. Expression of interferon-gamma and tumor necrosis factor-alpha in bone marrow T cells and their levels in bone marrow plasma in patients with aplastic anemia. Ann Hematol 2005;84:572-7
   PubMed Web of Science ®Google Scholar
• Dufour C, Corcione A, Svahn J, et al. Interferon gamma and tumour necrosis factor alpha are overexpressed in bone marrow T lymphocytes from paediatric patients with aplastic anaemia. Br J Haematol 2001;115:1023-31
   PubMed Web of Science ®Google Scholar
• Martínez-Jaramillo G, Flores-Figueroa E, Gómez-Morales E, et al. Tumor necrosis factor-alpha levels in long-term marrow cultures from patients with aplastic anemia: modulation by granulocyte-macrophage colony-stimulating factor. Am J Hematol 2001;68:144-8
   PubMedGoogle Scholar
• Rusten LS, Smeland EB, Jacobsen FW, et al. Tumor necrosis factor-alpha inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. Role of p55 and p75 tumor necrosis factor receptors. J Clin Invest 1994;94:165-72
   PubMed Web of Science ®Google Scholar
• Gu Y, Hu X, Liu C, et al. Interleukin (IL)-17 promotes macrophages to produce IL-8, IL-6 and tumour necrosis factor-alpha in aplastic anaemia. Br J Haematol 2008;142:109-14
   PubMed Web of Science ®Google Scholar
• Li J, Zhao Q, Xing W, et al. Interleukin-27 enhances the production of tumour necrosis factor-α and interferon-γ by bone marrow T lymphocytes in aplastic anaemia. Br J Haematol 2011;153:764-72
   PubMed Web of Science ®Google Scholar
• Speeckaert MM, Speeckaert R, Laute M, et al. Tumor necrosis factor receptors: biology and therapeutic potential in kidney diseases. Am J Nephrol 2012;36:261-70
   PubMed Web of Science ®Google Scholar
• Aggarwal BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 2003;3:745-56
   PubMed Web of Science ®Google Scholar
• Pennica D. Characterization of a recombinant extracellular domain of the type I tumor necrosis factor receptor: evidence for tumor necrosis factor-alpha induced receptor aggregation. Biochemistry 1992;31:1134-41
   PubMed Web of Science ®Google Scholar
• Gruss HJ, Duyster J, Herrmann F. Structural and biological features of the TNF receptor and TNF ligand superfamilies: interactive signals in the pathobiology of Hodgkin’s disease. Ann Oncol 1996;7 Suppl 4:19-26
   PubMedGoogle Scholar
• Apostolaki M, Armaka M, Victoratos P, et al. Cellular mechanisms of TNF function in models of inflammation and autoimmunity. Curr Dir Autoimmun 2010;11:1-26
   PubMedGoogle Scholar
• Croft M, Duan W, Choi H, et al. TNF superfamily in inflammatory disease: translating basic insights. Trends Immunol 2012;33:144-52
   PubMed Web of Science ®Google Scholar
• Pfeffer K. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine Growth Factor Rev 2003;14:185-91
   PubMed Web of Science ®Google Scholar
• Rusten LS, Jacobsen FW, Lesslauer W, et al. Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors. Blood 1994;83:3152-9
   PubMed Web of Science ®Google Scholar
• MacEwan DJ. TNF ligands and receptors-a matter of life and death. Br J Pharmacol 2002;135:855-75
   PubMed Web of Science ®Google Scholar
• Doganavsargil-Baysal O, Cinemre B, Aksoy UM, et al. Levels of TNF-α, soluble TNF receptors (sTNFR1, sTNFR2), and cognition in bipolar disorder. Hum Psychopharmacol 2013;28:160-7
   PubMed Web of Science ®Google Scholar
• Owczarek D, Cibor D, Głowacki MK, et al. TNF-α and soluble forms of TNF receptors 1 and 2 in the serum of patients with Crohn’s disease and ulcerative colitis. Pol Arch Med Wewn 2012;122:616-23
   PubMed Web of Science ®Google Scholar
• Shen R, Xu CG, Li LZ, et al. Study of the cellular immunity and Soluble TNF receptor in aplastic anemia. Curr Immunol 2004;24:206-9
   Google Scholar
• Laveder F, Marcolongo K. Uncontrolled triggering of programmed cell death (apoptosis) in haematopoietic stem cells; a new hypothesis for the pathogenesis of aplastic anaemia. Immunol Cell Biol 1996;74:159-62
   PubMed Web of Science ®Google Scholar
• Chen YF, Wu ZM, Xie C, et al. Expression level of IL-6 secreted by bone marrow stromal cells in mice with aplastic anemia. ISRN Hematol 2013;2013:986219
   PubMedGoogle Scholar
• Scopes J, Bagnara M, Gordon-Smith EC, et al. Haemopoietic progenitor cells are reduced in aplastic anaemia. Br J Haematol 1994;86:427-30
   PubMed Web of Science ®Google Scholar
• Philpott NJ, Scopes J, Marsh JC, et al. Increased apoptosis in aplastic anemia bone marrow progenitor cells: possible pathophysiologic significance. Exp Haematol 1995;23:1642-8
   PubMed Web of Science ®Google Scholar
• Liu CY, Fu R, Wang HQ, et al. Fas/FasL in the immune pathogenesis of severe aplastic anemia. Genet Mol Res 2014;13:4083-8
   PubMed Web of Science ®Google Scholar
• Imai Y, Kouzmenko A, Kato S. Targeting Fas/FasL signaling, a new strategy for maintaining bone health. Expert Opin Ther Targets 2011;15:1143-5
   PubMed Web of Science ®Google Scholar
• Killick SB, Cox CV, March JC, et al. Mechanisms of bone marrow progenitor cell apoptosis in aplastic anaemia and the effect of anti-thymocyte globulin: examination of the role of the Fas-FasL interaction. Br J Haematol 2000;111:1164-9
   PubMed Web of Science ®Google Scholar
• Maciejewski J, Sellei C, Auderson S, et al. Fas antigen expression CD34+ human marrow cells is induced by inferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 1995;85:3183-90
   PubMed Web of Science ®Google Scholar
• Maciejewski JP, Selleri C, Sato T, et al. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia. Br J Haematol 1995;91:245-52
   PubMed Web of Science ®Google Scholar
• Gersuk GM, Beckham C, Loken MR, et al. A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome. Br J Haematol 1998;103:176-88
   PubMed Web of Science ®Google Scholar
• Kasahara S, Hara T, Itoh H, et al. Hypoplastic myelodysplastic syndromes can be distinguished from acquired aplastic anaemia by bone marrow stem cell expression of the tumour necrosis factor receptor. Br J Haematol 2002;118:181-8
   PubMed Web of Science ®Google Scholar
• Welsh JP, Rutherford TR, Flynn J, et al. In vitro effects of interferon-gamma and tumor necrosis factor-alpha on CD34+ bone marrow progenitor cells from aplastic anemia patients and normal donors. Hematol J 2004;5:39-46
   PubMedGoogle Scholar
• Dybedal I, Bryder D, Fossum A, et al. Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells. Blood 2001;98:1782-91
   PubMed Web of Science ®Google Scholar
• Buck I, Morceau F, Cristofanon S, et al. Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. Biochem Pharmacol 2008;76:1229-39
   PubMed Web of Science ®Google Scholar
• Degterev A, Huang Z, Boyce M, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005;1:112-19
   PubMed Web of Science ®Google Scholar
• Lim SY, Davidson SM, Mocanu MM, et al. The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore. Cardiovasc Drugs Ther 2007;21:467-9
   PubMed Web of Science ®Google Scholar
• Smith CC, Davidson SM, Lim SY, et al. Necrostatin: a potentially novel cardioprotective agent? Cardiovasc Drugs Ther 2007;21:227-33
   PubMed Web of Science ®Google Scholar
• Cho YS, Challa S, Moquin D, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009;137:1112-23
   PubMed Web of Science ®Google Scholar
• Upton JW, Kaiser WJ, Mocarski ES. Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe 2010;7:302-13
   PubMed Web of Science ®Google Scholar
• Han W, Li L, Qiu S, et al. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther 2007;6:1641-9
   PubMedGoogle Scholar
• Zhang QL, Niu Q, Niu PY, et al. Novel interventions targeting on apoptosis and necrosis induced by aluminum chloride in neuroblastoma cells. J Biol Regul Homeost Agents 2010;24:137-48
   PubMedGoogle Scholar
• Chen IL, Tsau JS, Molkentin JD, et al. Mechanism of necroptosis in T cells. J Exp Med 2011;208:633-41
   PubMedGoogle Scholar
• Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006;443:787-95
   PubMed Web of Science ®Google Scholar
• Zhu S, Zhang Y, Bai G, et al. Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington’s disease. Cell Death Dis 2011;2:e115
   PubMed Web of Science ®Google Scholar
• Li Y, Yang X, Ma C, et al. Necroptosis contributes to the NMDA-induced excitotoxicity in rat’s cultured cortical neurons. Neurosci Lett 2008;447:120-3
   PubMed Web of Science ®Google Scholar
• Bonnet MC, Preukschat D, Welz PS, et al. The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 2011;35:572-82
   PubMed Web of Science ®Google Scholar
• Günther C, Martini E, Wittkopf N, et al. Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. Nature 2011;477:335-9
   PubMed Web of Science ®Google Scholar
• Xie WL, Wang HQ, Wu QP. The molecular mechanism of necroptosis. Int J Anesth Resus 2012;33:829-32
   Google Scholar
• He S, Wang L, Miao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009;137:1100-11
   PubMed Web of Science ®Google Scholar
• Vandenabeele P, Galluzzi L, Vanden Berghe T, et al. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 2010;11:700-14
   PubMed Web of Science ®Google Scholar
• Li J, McQuade T, Siemer AB, et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 2012;150:339-50
   PubMed Web of Science ®Google Scholar
• Kikuchi M, Kuroki S, Kayama M, et al. Protease activity of procaspase-8 is essential for cell survival by inhibiting both apoptotic and nonapoptotic cell death dependent on receptor-interacting protein kinase 1 (RIP1) and RIP3. J Biol Chem 2012;287:41165-73
   PubMed Web of Science ®Google Scholar
• Hitomi J, Christofferson DE, Ng A, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008;135:1311-23
   PubMed Web of Science ®Google Scholar
• He S, Wang L, Miao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009;137:1100-11
   PubMed Web of Science ®Google Scholar
• Zhang DW, Shao J, Lin J, et al. RIP3,an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009;325:332-6
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Vitale I, Abrams JM, et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 2012;19:107-20
   PubMed Web of Science ®Google Scholar
• Xiao Y, Li H, Zhang J, et al. TNF-α/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations. Blood 2011;118:6057-67
   PubMed Web of Science ®Google Scholar
• Chen YF, Zhao ZQ, Wu ZM, et al. The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. Int J Clin Exp Pathol 2014;7:8411-20
   PubMed Web of Science ®Google Scholar
• Liu P, Xu B, Shen W, et al. Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1. Leukemia 2012;26:1293-300
   PubMed Web of Science ®Google Scholar
• Li J, Zhao Q, Xing W, et al. Interleukin-27 enhances the production of tumour necrosis factor-α and interferon-γ by bone marrow T lymphocytes in aplastic anaemia. Br J Haematol 2011;153:764-72
   PubMed Web of Science ®Google Scholar
• Espinoza JL, Takamatsu H, Lu X, et al. Anti-moesin antibodies derived from patients with aplastic anemia stimulate monocytic cells to secrete TNF-alpha through an ERK1/2-dependent pathway. Int Immunol 2009;21:913-23
   PubMed Web of Science ®Google Scholar
• Bestach Y, Sieza Y, Attie M, et al. Polymorphisms in TNF and IFNG are associated with clinical characteristics of aplastic anemia in Argentinean population. Leuk Lymphoma 2014;24:1-12
   Google Scholar
• Zhao S, Mei K, Qian L, et al. Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo. Cell Physiol Biochem 2013;32:549-60
   PubMedGoogle Scholar
• Zhai CY, Wei W, Ji AF. et al. Effect of brucine on secretion function and proliferation capability of T lymphocytes in patients with aplastic anemia. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2011;19:435-8
   PubMedGoogle Scholar