Advances in the management of childhood portal hypertension

References

• Witters P, Libbrecht L, Roskams T, et al. Noncirrhotic presinusoidal portal hypertension is common in cystic fibrosis-associated liver disease. Hepatology 2011;53(3):1064-5
   PubMed Web of Science ®Google Scholar
• Feu F, Garcia-Pagan JC, Bosch J, et al. Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet 1995;346(8982):1056-9
   PubMed Web of Science ®Google Scholar
• Garcia-Tsao G, Bosch J, Groszmann RJ. Portal hypertension and variceal bleeding--unresolved issues. Summary of an American Association for the study of liver diseases and European Association for the study of the liver single-topic conference. Hepatology 2008;47(5):1764-72
   PubMedGoogle Scholar
• De Franchis R. Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2010;53(4):762-8
   PubMed Web of Science ®Google Scholar
• Woolfson J, John P, Kamath B, et al. Measurement of hepatic venous pressure gradient is feasible and safe in children. J Pediatr Gastroenterol Nutr 2013;57(5):634-7
   PubMed Web of Science ®Google Scholar
• Miraglia R, Luca A, Maruzzelli L, et al. Measurement of hepatic vein pressure gradient in children with chronic liver diseases. J Hepatol 2010;53(4):624-9
   PubMed Web of Science ®Google Scholar
• Heyman MB, LaBerge JM. Role of transjugular intrahepatic portosystemic shunt in the treatment of portal hypertension in pediatric patients. J Pediatr Gastroenterol Nutr 1999;29(3):240-9
   PubMed Web of Science ®Google Scholar
• Gugig R, Rosenthal P. Management of portal hypertension in children. World J Gastroenterol 2012;18(11):1176-84
   PubMed Web of Science ®Google Scholar
• Fagundes ED, Ferreira AR, Roquete ML, et al. Clinical and laboratory predictors of esophageal varices in children and adolescents with portal hypertension syndrome. J Pediatr Gastroenterol Nutr 2008;46(2):178-83
   PubMed Web of Science ®Google Scholar
• de Alcantara RV, Yamada RM, Cardoso SR, et al. Ultrasonographic predictors of esophageal varices. J Pediatr Gastroenterol Nutr 2013;57(6):700-3
   PubMed Web of Science ®Google Scholar
• McKiernan PJ, Sharif K, Gupte GL. The role of endoscopic ultrasound for evaluating portal hypertension in children being assessed for intestinal transplantation. Transplantation 2008;86(10):1470-3
   PubMed Web of Science ®Google Scholar
• De Lisi S, Buscarini E. Endoscopic ultrasonography and portal hypertension: where are we in 2009? Eur J Gastroenterol Hepatol 2009;21(12):1327-32
   PubMed Web of Science ®Google Scholar
• Thabut D, Moreau R, Lebrec D. Noninvasive assessment of portal hypertension in patients with cirrhosis. Hepatology 2011;53(2):683-94
   PubMed Web of Science ®Google Scholar
• Gana JC, Turner D, Roberts EA, Ling SC. Derivation of a clinical prediction rule for the noninvasive diagnosis of varices in children. J Pediatr Gastroenterol.Nutr 2010;50(2):188-93
   PubMed Web of Science ®Google Scholar
• Gana JC, Turner D, Mieli-Vergani G, et al. A clinical prediction rule and platelet count predict esophageal varices in children. Gastroenterology 2011;141(6):2009-16
   PubMed Web of Science ®Google Scholar
• Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003;38(2):518-26
   PubMed Web of Science ®Google Scholar
• Park SH, Park TE, Kim YM, et al. Non-invasive model predicting clinically-significant portal hypertension in patients with advanced fibrosis. J Gastroenterol Hepatol 2009;24(7):1289-93
   PubMed Web of Science ®Google Scholar
• Giannini EG, Zaman A, Kreil A, et al. Platelet count/spleen diameter ratio for the noninvasive diagnosis of esophageal varices: results of a multicenter, prospective, validation study. Am J Gastroenterol 2006;101(11):2511-19
   PubMed Web of Science ®Google Scholar
• Adami MR, Ferreira CT, Kieling CO, et al. Noninvasive methods for prediction of esophageal varices in pediatric patients with portal hypertension. World J Gastroenterol 2013;19(13):2053-9
   PubMed Web of Science ®Google Scholar
• Jalan R, Hayes PC. UK guidelines on the management of variceal haemorrhage in cirrhotic patients. British Society of Gastroenterology. Gut 2000;46(Suppl 3-4):III1-III15
   PubMedGoogle Scholar
• De Franchis R. Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2005;43(1):167-76
   PubMed Web of Science ®Google Scholar
• Bernard O, Alvarez F, Brunelle F, et al. Portal hypertension in children. Clin Gastroenterol 1985;14(1):33-55
   PubMedGoogle Scholar
• Wanty C, Helleputte T, Smets F, et al. Assessment of risk of bleeding from esophageal varices during management of biliary atresia in children. J Pediatr Gastroenterol Nutr 2013;56(5):537-43
   PubMed Web of Science ®Google Scholar
• Shneider BL, Bosch J, De Franchis R, et al. Portal hypertension in children: expert pediatric opinion on the report of the Baveno v Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension. Pediatr Transplant 2012;16(5):426-37
   PubMed Web of Science ®Google Scholar
• Ling SC, Walters T, McKiernan PJ, et al. Primary prophylaxis of variceal hemorrhage in children with portal hypertension: a framework for future research. J Pediatr Gastroenterol Nutr 2011;52(3):254-61
   PubMed Web of Science ®Google Scholar
• Lykavieris P, Gauthier F, Hadchouel P, et al. Risk of gastrointestinal bleeding during adolescence and early adulthood in children with portal vein obstruction. J Pediatr 2000;136(6):805-8
   PubMed Web of Science ®Google Scholar
• McKiernan PJ. Treatment of variceal bleeding. Gastrointest Endosc Clin N Am 2001;11(4):789-812; viii
   PubMedGoogle Scholar
• Duche M, Ducot B, Tournay E, et al. Prognostic value of endoscopy in children with biliary atresia at risk for early development of varices and bleeding. Gastroenterology 2010;139(6):1952-60
   PubMed Web of Science ®Google Scholar
• Goncalves ME, Cardoso SR, Maksoud JG. Prophylactic sclerotherapy in children with esophageal varices: long-term results of a controlled prospective randomized trial. J Pediatr Surg 2000;35(3):401-5
   PubMed Web of Science ®Google Scholar
• Cano I, Urruzuno P, Medina E, et al. Treatment of esophageal varices by endoscopic ligation in children. Eur J Pediatr Surg 1995;5(5):299-302
   PubMed Web of Science ®Google Scholar
• Sasaki T, Hasegawa T, Nakajima K, et al. Endoscopic variceal ligation in the management of gastroesophageal varices in postoperative biliary atresia. J Pediatr Surg 1998;33(11):1628-32
   PubMed Web of Science ®Google Scholar
• Celinska-Cedro D, Teisseyre M, Woynarowski M, et al. Endoscopic ligation of esophageal varices for prophylaxis of first bleeding in children and adolescents with portal hypertension: preliminary results of a prospective study. J Pediatr Surg 2003;38(7):1008-11
   PubMed Web of Science ®Google Scholar
• Duche M, Habes D, Roulleau P, et al. Prophylactic endoscopic sclerotherapy of large esophagogastric varices in infants with biliary atresia. Gastrointest Endosc 2008;67(4):732-7
   PubMed Web of Science ®Google Scholar
• Reiberger T, Ulbrich G, Ferlitsch A, et al. Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol. Gut 2012
   Google Scholar
• D’Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a meta-analytic review. Hepatology 1995;22(1):332-54
   PubMed Web of Science ®Google Scholar
• Ozsoylu S, Kocak N, Demir H, et al. Propranolol for primary and secondary prophylaxis of variceal bleeding in children with cirrhosis. Turk J Pediatr 2000;42(1):31-3
   PubMed Web of Science ®Google Scholar
• Erkan T, Cullu F, Kutlu T, et al. Management of portal hypertension in children: a retrospective study with long-term follow-up. Acta Gastroenterol Belg 2003;66(3):213-17
   PubMed Web of Science ®Google Scholar
• Shashidhar H, Langhans N, Grand RJ. Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study. J Pediatr Gastroenterol Nutr 1999;29(1):12-17
   PubMed Web of Science ®Google Scholar
• Eroglu Y, Emerick KM, Whitingon PF, Alonso EM. Octreotide therapy for control of acute gastrointestinal bleeding in children. J Pediatr Gastroenterol Nutr 2004;38(1):41-7
   PubMed Web of Science ®Google Scholar
• Stringer MD, Howard ER, Mowat AP. Endoscopic sclerotherapy in the management of esophageal varices in 61 children with biliary atresia. J Pediatr Surg 1989;24(5):438-42
   PubMed Web of Science ®Google Scholar
• van Heurn LW, Saing H, Tam PK. Portoenterostomy for biliary atresia: long-term survival and prognosis after esophageal variceal bleeding. J Pediatr Surg 2004;39(1):6-9
   PubMed Web of Science ®Google Scholar
• Mitra SK, Kumar V, Datta DV, et al. Extrahepatic portal hypertension: a review of 70 cases. J Pediatr Surg 1978;13(1):51-7
   PubMed Web of Science ®Google Scholar
• Alvarez F, Bernard O, Brunelle F, et al. Portal obstruction in children. I. Clinical investigation and hemorrhage risk. J Pediatr 1983;103(5):696-702
   PubMed Web of Science ®Google Scholar
• Shneider B, Emre S, Groszmann R, et al. Expert pediatric opinion on the Report of the Baveno IV Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension. Pediatr Transplant 2006;10(8):893-907
   PubMed Web of Science ®Google Scholar
• Banares R, Albillos A, Rincon D, et al. Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis. Hepatology 2002;35(3):609-15
   PubMed Web of Science ®Google Scholar
• McKiernan PJ, Beath SV, Davison SM. A prospective study of endoscopic esophageal variceal ligation using a multiband ligator. J Pediatr Gastroenterol Nutr 2002;34(2):207-11
   PubMed Web of Science ®Google Scholar
• Fox VL, Carr-Locke DL, Connors PJ, Leichtner AM. Endoscopic ligation of esophageal varices in children. J Pediatr Gastroenterol Nutr 1995;20(2):202-8
   PubMed Web of Science ®Google Scholar
• Hall RJ, Lilly JR, Stiegmann GV. Endoscopic esophageal varix ligation: technique and preliminary results in children. J Pediatr Surg 1988;23(12):1222-3
   PubMed Web of Science ®Google Scholar
• Wilde J, Teixeira P, Bramhall SR, et al. Liver transplantation in haemophilia. Br J Haematol 2002;117(4):952-6
   PubMed Web of Science ®Google Scholar
• Steventon DM, Kelly DA, McKiernan P, et al. Emergency transjugular intrahepatic portosystemic shunt prior to liver transplantation. Pediatr Radiol 1997;27(1):84-6
   PubMed Web of Science ®Google Scholar
• Superina RA, Alonso EM. Medical and surgical management of portal hypertension in children. Curr Treat Options Gastroenterol 2006;9:432-43
   PubMedGoogle Scholar
• Fidelman N, Kwan SW, LaBerge JM, et al. The transjugular intrahepatic portosystemic shunt: an update. AJR Am J Roentgenol 2012;199(4):746-55
   PubMed Web of Science ®Google Scholar
• Pomier-Layrargues G, Bouchard L, Lafortune M, et al. The transjugular intrahepaticportosystemic shunt in the treatment of portal hypertension:current status. Int J Hepatol 2012;2012: 167868
   PubMedGoogle Scholar
• Leblebisatan G, Sasmaz I, Antmen B, et al. Management of life-threatening hemorrhages and unsafe interventions in nonhemophiliac children by recombinant factor VIIa. Clin Appl Thromb Hemost 2010;16(1):77-82
   PubMed Web of Science ®Google Scholar
• Vickers CR, O’Connor HJ, Quintero GA, et al. Delayed perforation of the esophagus after variceal sclerotherapy and hepatic transplantation. Gastrointest Endosc 1989;35(5):459-61
   PubMed Web of Science ®Google Scholar
• Shneider B, Emre S, Groszmann R, et al. Expert pediatric opinion on the Report of the Baveno IV Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension. Pediatr Transplant 2006;10(8):893-907
   PubMed Web of Science ®Google Scholar
• Zargar SA, Javid G, Khan BA, et al. Endoscopic ligation vs. sclerotherapy in adults with extrahepatic portal venous obstruction: a prospective randomized study. Gastrointest Endosc 2005;61(1):58-66
   PubMed Web of Science ®Google Scholar
• De Ville de Goyet J, Lo Zupone C, Grimaldi C. D_Ambrosio G, Candusso M, Torre G, et al. Meso-Rex bypass as an alternative technique for portal vein reconstruction at or after liver transplantation in children: review and perspectives. Pediatr Transplantation 2013;17:19-26
   PubMed Web of Science ®Google Scholar
• Superina R, Bambini DA, Lokar J, et al. Correction of Extrahepatic Portal Vein Thrombosis by the Mesenteric to Left Portal Vein Bypass.Ann Surg. 2006;243(4):515-21
   Google Scholar
• Puppala S, Patel J, Woodley H, et al. Preoperative imaging of left portal vein at the Rex recess for Rex shunt formation using wedged hepatic vein carbon dioxide portography. J Pediatr Surg 2009;44(10):2043-7
   PubMed Web of Science ®Google Scholar
• Lawson AJ, Rischbieter P, Numanoglu A, et al. Imaging the Rex vein preoperatively using wedged hepatic venous portography. Pediatr Radiol 2011;41:1246-9
   PubMed Web of Science ®Google Scholar
• Mack CL, Zelko FA, Lokar J, et al. Surgically restoring portal blood flow to the liver in children with primary extrahepatic portal vein thrombosis improves fluid neurocognitive ability. Pediatrics 2006;117(3):e405-12
   Web of Science ®Google Scholar
• Sharif K, McKiernan P, De Ville de Goyet J. Mesoportal bypass for extrahepatic portal vein obstruction in children: close to a cure for most!. J Pediatr Surg 2010;45(1):272-6
   PubMed Web of Science ®Google Scholar
• Superina R, Shneider B, Emre S, et al. Surgical guidelines for the management of extra-hepatic portal vein obstruction. Pediatr Transplant 2006;10(8):908-13
   PubMed Web of Science ®Google Scholar
• Orloff MJ, Orloff MS, Girard B, Orloff SL. Bleeding esophagogastric varices from extrahepatic portal hypertension: 40 years’ experience with portal-systemic shunt. J Am Coll Surg 2002;194(6):717-28
   PubMed Web of Science ®Google Scholar
• Chiu B, Superina RA. Encephalopathy caused by a splenorenal shunt can be reversed by performing a mesenteric-to-left portal vein bypass. J Pediatr Surg 2006;41(6):1177-9
   PubMed Web of Science ®Google Scholar
• Willis AD, Miloh TA, Arnon R, et al. Hepatopulmonary syndrome in children - is conventional liver transplantation always needed? Clin Transplant 2011;25(6):849-55
   PubMed Web of Science ®Google Scholar
• Fuchs J, Warmann S, Kardorff R, et al. Mesenterico-left portal vein bypass in children with congenital extrahepatic portal vein thrombosis: a unique curative approach. J Pediatr Gastroenterol Nutr 2003;36(2):213-16
   PubMed Web of Science ®Google Scholar
• GROOVE. Available from: http://groovestudy.org/
   Google Scholar