Omega-3 fatty acids: a potential future treatment for asthma?

References

• Horrobin DF. Low prevalences of coronary heart disease (CHD), psoriasis, asthma and rheumatoid arthritis in Eskimos: are they caused by high dietary intake of eicosapentaenoic acid (EPA), a genetic variation of essential fatty acid (EFA) metabolism or a combination of both? Med. Hypotheses 22(4), 421–428 (1987).
   PubMed Web of Science ®Google Scholar
• Serhan CN. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol. 25, 101–137 (2007).
   PubMed Web of Science ®Google Scholar
• Mickleborough TD, Lindley MR, Ionescu AA, Fly AD. Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma. Chest 29(1), 39–49 (2006).
   Google Scholar
• Mickleborough TD, Tecklenburg SL, Montgomery GS, Lindley MR. Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. Clin. Nutr. 28(1), 71–77 (2009).
   PubMed Web of Science ®Google Scholar
• Tecklenburg-Lund S, Mickleborough TD, Turner LA, Fly AD, Stager JM, Montgomery GS. Randomized controlled trial of fish oil and montelukast and their combination on airway inflammation and hyperpnea-induced bronchoconstriction. PLoS ONE 5(10), e13487 (2010).
   Web of Science ®Google Scholar
• Dry J, Vincent D. Effect of a fish oil diet on asthma: results of a 1-year double-blind study. Int. Arch. Allergy Appl. Immunol. 95(2–3), 156–157 (1991).
   PubMedGoogle Scholar
• Nagakura T, Matsuda S, Shichijyo K, Sugimoto H, Hata K. Dietary supplementation with fish oil rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma. Eur. Respir. J. 16(5), 861–865 (2000).
   PubMed Web of Science ®Google Scholar
• Biltagi MA, Baset AA, Bassiouny M, Kasrawi MA, Attia M. Omega-3 fatty acids, vitamin C and Zn supplementation in asthmatic children: a randomized self-controlled study. Acta Paediatr. 98(4), 737–742 (2009).
   PubMed Web of Science ®Google Scholar
• Broughton KS, Johnson CS, Pace BK, Liebman M, Kleppinger KM. Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production. Am. J. Clin. Nutr. 65(4), 1011–1017 (1997).
   PubMed Web of Science ®Google Scholar
• Schubert R, Kitz R, Beermann C et al. Effect of n-3 polyunsaturated fatty acids in asthma after low-dose allergen challenge. Int. Arch. Allergy Immunol. 148(4), 321–329 (2009).
   PubMed Web of Science ®Google Scholar
• Sallam M, Motaleb F, Ahmed M, Mahmoud A. Anti-inflammatory effect of Omega-3 polyunsaturated fatty acids in children with bronchial asthma; relation to nuclear factor-kappa B (NF-κB) and inflammatory cytokines IL-12 and IL-13. Egypt. J. Biochem. Mol. Biol. 28(2), (2010).
   Google Scholar
• Mihrshahi S, Peat JK, Marks GB et al. Eighteen-month outcomes of house dust mite avoidance and dietary fatty acid modification in the Childhood Asthma Prevention Study (CAPS). J. Allergy Clin. Immunol. 111(1), 162–168 (2003).
   PubMed Web of Science ®Google Scholar
• Kremmyda LS, Vlachava M, Noakes PS, Diaper ND, Miles EA, Calder PC. Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fatty acids: a systematic review. Clin. Rev. Allergy Immunol. 41(1), 36–66 (2011).
   PubMed Web of Science ®Google Scholar
• Thien FC, De Luca S, Woods RK, Abramson MJ. Dietary marine fatty acids (fish oil) for asthma in adults and children. Cochrane Database Syst. Rev. (2), CD001283 (2010).
   Google Scholar
• Mickleborough TD, Vaughn CL, Shei R-J, Davis EM, Wilhite DP. Marine lipid fraction PCSO-524 (lyprinol/omega XL) of the New Zealand green lipped mussel attenuates hyperpnea-induced bronchoconstriction in asthma. Respir. Med. 197, 1152–1163 (2013).
   Web of Science ®Google Scholar
• Emelyanov A, Fedoseev G, Krasnoschekova O, Abulimity A, Trendeleva T, Barnes PJ. Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial. Eur. Respir. J. 20(3), 596–600 (2002).
   PubMed Web of Science ®Google Scholar
• Wood LG, Hazlewood LC, Foster PS, Hansbro PM. Lyprinol reduces inflammation and improves lung function in a mouse model of allergic airways disease. Clin. Experiment. Allergy 40(12), 1785–1793 (2010).
   PubMed Web of Science ®Google Scholar
• Wakimoto T, Kondo H, Nii H et al. Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus. Proc. Natl Acad. Sci. U.S.A. 108(42), 17533–17537 (2011).
   PubMed Web of Science ®Google Scholar
• Bouchard-Mercier A, Rudkowska I, Lemieux S, Couture P, Vohl M-C. Polymorphisms, de novo lipogenesis and plasma triglyceride response following fish oil supplementation. J. Lipid Res. (2013).
   Google Scholar
• Fortenko O, Zeki A, Schuster G et al. Asthma patients with specific genotypes identified for fish oil treatment trial. Calif. Agr. 65(3), 112–117 (2011).
   Web of Science ®Google Scholar