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Are proton pump inhibitors associated with the development of community-acquired pneumonia? A meta-analysis

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Pages 337-344 | Published online: 10 Jan 2014

References

  • Ahrens D, Chenot JF, Behrens G, Grimmsmann T, Kochen MM. Appropriateness of treatment recommendations for PPI in hospital discharge letters. Eur. J. Clin. Pharmacol.66(12), 1265–1271 (2010).
  • Grant K, Al-Adhami N, Tordoff J, Livesey J, Barbezat G, Reith D. Continuation of proton pump inhibitors from hospital to community. Pharm. World Sci.28(4), 189–193 (2006).
  • Heidelbaugh JJ, Goldberg KL, Inadomi JM. Magnitude and economic effect of overuse of antisecretory therapy in the ambulatory care setting. Am. J. Manag. Care16(9), E228–E234 (2010).
  • Naunton M, Peterson G, Bleasel M. Overuse of proton pump inhibitors. J. Clin. Pharm. Ther.25(5), 333–340 (2000).
  • Berardi RR. A critical evaluation of proton pump inhibitors in the treatment of gastroesophageal reflux disease. Am. J. Manag. Care6(Suppl. 9), S491–S505 (2000).
  • Berardi RR, Welage LS. Proton-pump inhibitors in acid-related diseases. Am. J. Health Syst. Pharm.55(21), 2289–2298 (1998).
  • Eom CS, Jeon CY, Lim JW, Cho EG, Park SM, Lee KS. Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis. CMAJ183(3), 310–319 (2011).
  • Johnstone J, Nerenberg K, Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia. Aliment. Pharmacol. Ther.31(11), 1165–1177 (2010).
  • Deshpande A, Pant C, Pasupuleti V et al. Association between proton pump inhibitor therapy and Clostridium difficile infection in a meta-analysis. Clin. Gastroenterol. Hepatol.10(3), 225–233 (2011).
  • Yang YX, Lewis JD, Epstein S, Metz DC. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA296(24), 2947–2953 (2006).
  • Harmark L, van Der Wiel HE, De Groot MC, van Grootheest AC. Proton pump inhibitor-induced acute interstitial nephritis. Br. J. Clin. Pharmacol.64(6), 819–823 (2007).
  • Christensen KL, Holman RC, Steiner CA, Sejvar JJ, Stoll BJ, Schonberger LB. Infectious disease hospitalizations in the United States. Clin. Infect. Dis.49(7), 1025–1035 (2009).
  • Marrie TJ, Shariatzadeh MR. Community-acquired pneumonia requiring admission to an intensive care unit: a descriptive study. Medicine (Baltimore)86(2), 103–111 (2007).
  • Restrepo MI, Mortensen EM, Velez JA, Frei C, Anzueto A. A comparative study of community-acquired pneumonia patients admitted to the ward and the ICU. Chest133(3), 610–617 (2008).
  • Lim WS, van Der Eerden MM, Laing R et al. Defining community-acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax58(5), 377–382 (2003).
  • Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the medicare fee-for-service program. N. Engl. J. Med.360(14), 1418–1428 (2009).
  • Schappert SM, Rechtsteiner EA. Ambulatory medical care utilization estimates for 2006. Natl Health Stat. Report8, 1–29 (2008).
  • File TM Jr, Marrie TJ. Burden of community-acquired pneumonia in North American adults. Postgrad. Med.122(2), 130–141 (2010).
  • Theisen J, Nehra D, Citron D et al. Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J. Gastrointest. Surg.4(1), 50–54 (2000).
  • Thorens J, Froehlich F, Schwizer W et al. Bacterial overgrowth during treatment with omeprazole compared with cimetidine: a prospective randomized double blind study. Gut39, 54–59 (1996).
  • Thomson AB, Sauve MD, Kassam N, Kamitakahara H. Safety of the long-term use of proton pump inhibitors. World J. Gastroenterol.16(19), 2323–2330 (2010).
  • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ339, B2535 (2009).
  • Wessling A, Boethius G. Measurement of drug use in a defined population. Evaluation of the defined daily dose (DDD) methodology. Eur. J. Clin. Pharmacol.39(3), 207–210 (1990).
  • Eurich DT, Sadowski CA, Simpson SH, Marrie TJ, Majumdar SR. Recurrent community-acquired pneumonia in patients starting acid-suppressing drugs. Am. J. Med.123(1), 47–53 (2010).
  • Herzig SJ, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA301(20), 2120–2128 (2009).
  • Estborn L, Joelson S. Occurrence of community-acquired respiratory tract infection in patients receiving esomeprazole: retrospective analysis of adverse events in 31 clinical trials. Drug Saf.31(7), 627–636 (2008).
  • Roughead EE, Ramsay EN, Pratt NL, Ryan P, Gilbert AL. Proton-pump inhibitors and the risk of antibiotic use and hospitalisation for pneumonia. Med. J. Aust.190(3), 114–116 (2009).
  • Redelmeier DA, Mcalister FA, Kandel CE, Lu H, Daneman N. Postoperative pneumonia in elderly patients receiving acid suppressants: a retrospective cohort analysis. BMJ340, C2608 (2010).
  • Dublin S, Walker RL, Jackson ML, Nelson JC, Weiss NS, Jackson LA. Use of proton pump inhibitors and H2 blockers and risk of pneumonia in older adults: a population-based case–control study. Pharmacoepidemiol. Drug Saf.19(8), 792–802 (2010).
  • Gulmez SE, Holm A, Frederiksen H, Jensen TG, Pedersen C, Hallas J. Use of proton pump inhibitors and the risk of community-acquired pneumonia: a population-based case–control study. Arch. Intern. Med.167(9), 950–955 (2007).
  • Laheij RJ, Sturkenboom MC, Hassing RJ, Dieleman J, Stricker BH, Jansen JB. Risk of community-acquired pneumonia and use of gastric acid-suppressive drugs. JAMA292(16), 1955–1960 (2004).
  • Marciniak C, Korutz AW, Lin E, Roth E, Welty L, Lovell L. Examination of selected clinical factors and medication use as risk factors for pneumonia during stroke rehabilitation: a case–control study. Am. J. Phys. Med. Rehabil.88(1), 30–38 (2009).
  • Myles PR, Hubbard RB, Mckeever TM, Pogson Z, Smith CJ, Gibson JE. Risk of community-acquired pneumonia and the use of statins, ace inhibitors and gastric acid suppressants: a population-based case–control study. Pharmacoepidemiol. Drug Saf.18(4), 269–275 (2009).
  • Rodriguez LA, Ruigomez A, Wallander MA, Johansson S. Acid-suppressive drugs and community-acquired pneumonia. Epidemiology20(6), 800–806 (2009).
  • Sarkar M, Hennessy S, Yang YX. Proton-pump inhibitor use and the risk for community-acquired pneumonia. Ann. Intern. Med.149(6), 391–398 (2008).
  • Stang A. Critical evaluation of the Newcastle–Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur. J. Epidemiol.25(9), 603–605 (2010).
  • Welte T. Risk factors and severity scores in hospitalized patients with community-acquired pneumonia: prediction of severity and mortality. Eur. J. Clin. Microbiol. Infect. Dis.31(1), 33–47 (2011).
  • Gupta R, Garg P, Kottoor R et al. Overuse of acid suppression therapy in hospitalized patients. South Med. J.103(3), 207–211 (2010).
  • Zink DA, Pohlman M, Barnes M, Cannon ME. Long-term use of acid suppression started inappropriately during hospitalization. Aliment. Pharmacol. Ther.21(10), 1203–1209 (2005).
  • Murphy CE, Stevens AM, Ferrentino N et al. Frequency of inappropriate continuation of acid suppressive therapy after discharge in patients who began therapy in the surgical intensive care unit. Pharmacotherapy28(8), 968–976 (2008).
  • Wohlt PD, Hansen LA, Fish JT. Inappropriate continuation of stress ulcer prophylactic therapy after discharge. Ann. Pharmacother.41(10), 1611–1616 (2007).

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