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Review

The role of antimicrobials in Crohn’s disease

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Pages 281-288 | Published online: 10 Jan 2014

References

  • Prantera C, Scribano ML. Antibiotics and probiotics in inflammatory bowel disease: why, when, and how. Curr. Opin. Gastroenterol. 25(4), 329–333 (2009).
  • Abraham C, Cho JH. Inflammatory bowel disease. N. Engl. J. Med. 361(21), 2066–2078 (2009).
  • Macfarlane S, Steed H, Macfarlane GT. Intestinal bacteria and inflammatory bowel disease. Crit. Rev. Clin. Lab. Sci. 46(1), 25–54 (2009).
  • BestWR, BecktelJM, SingletonJW, KernF Jr. Development of a Crohn’s disease activity index. National Cooperative Crohn’s Disease Study. Gastroenterology 70(3), 439–444 (1976).
  • Lichtenstein GR, Hanauer SB, Sandborn WJ; Practice Parameters Committee of American College of Gastroenterology. Management of Crohn’s disease in adults. Am. J. Gastroenterol. 104(2), 465–483; quiz 464, 484 (2009).
  • Blichfeldt P, Blomhoff JP, Myhre E, Gjone E. Metronidazole in Crohn’s disease. A double blind cross-over clinical trial. Scand. J. Gastroenterol. 13(1), 123–127 (1978).
  • Sutherland L, Singleton J, Sessions J et al. Double blind, placebo controlled trial of metronidazole in Crohn’s disease. Gut 32(9), 1071–1075 (1991).
  • Rosén A, Ursing B, Alm T et al. A comparative study of metronidazole and sulfasalazine for active Crohn’s disease: the cooperative Crohn’s disease study in Sweden. I. Design and methodologic considerations. Gastroenterology 83(3), 541–549 (1982).
  • Ursing B, Alm T, Bárány F et al. A comparative study of metronidazole and sulfasalazine for active Crohn’s disease: the cooperative Crohn’s disease study in Sweden. II. Result. Gastroenterology 83(3), 550–562 (1982).
  • Ambrose NS, Allan RN, Keighley MR et al. Antibiotic therapy for treatment in relapse of intestinal Crohn’s disease. A prospective randomized study. Dis. Colon Rectum 28(2), 81–85 (1985).
  • Arnold GL, Beaves MR, Pryjdun VO, Mook WJ. Preliminary study of ciprofloxacin in active Crohn’s disease. Inflamm. Bowel Dis. 8(1), 10–15 (2002).
  • West RL, Van Der Woude CJ, Hansen BE et al. Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn’s disease with infliximab: a double-blind placebo-controlled study. Aliment. Pharmacol. Ther. 20(11–12), 1329–1336 (2004).
  • Colombel JF, Lémann M, Cassagnou M et al. A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn’s disease. Groupe d’Etudes Thérapeutiques des Affections Inflammatoires Digestives (GETAID). Am. J. Gastroenterol. 94(3), 674–678 (1999).
  • Thia KT, Mahadevan U, Feagan BG et al. Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn’s disease: a randomized, double-blind, placebo-controlled pilot study. Inflamm. Bowel Dis. 15(1), 17–24 (2009).
  • Steinhart AH, Feagan BG, Wong CJ et al. Combined budesonide and antibiotic therapy for active Crohn’s disease: a randomized controlled trial. Gastroenterology 123(1), 33–40 (2002).
  • Prantera C, Zannoni F, Scribano ML et al. An antibiotic regimen for the treatment of active Crohn’s disease: a randomized, controlled clinical trial of metronidazole plus ciprofloxacin. Am. J. Gastroenterol. 91(2), 328–332 (1996).
  • Leiper K, Martin K, Ellis A, Watson AJ, Morris AI, Rhodes JM. Clinical trial: randomized study of clarithromycin versus placebo in active Crohn’s disease. Aliment. Pharmacol. Ther. 27(12), 1233–1239 (2008).
  • Prantera C, Lochs H, Campieri M et al. Antibiotic treatment of Crohn’s disease: results of a multicentre, double blind, randomized, placebo-controlled trial with rifaximin. Aliment. Pharmacol. Ther. 23(8), 1117–1125 (2006).
  • Prantera C, Lochs H, Grimaldi M, Danese S, Scribano ML, Gionchetti P; Retic Study Group (Rifaximin-Eir Treatment in Crohn’s Disease). Rifaximin-extended intestinal release induces remission in patients with moderately active Crohn’s disease. Gastroenterology 142(3), 473–481.e4 (2012).
  • Rutgeerts P, Hiele M, Geboes K et al. Controlled trial of metronidazole treatment for prevention of Crohn’s recurrence after ileal resection. Gastroenterology 108(6), 1617–1621 (1995).
  • Rutgeerts P, Van Assche G, Vermeire S et al. Ornidazole for prophylaxis of postoperative Crohn’s disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology 128(4), 856–861 (2005).
  • Khan KJ, Ullman TA, Ford AC et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am. J. Gastroenterol. 106(4), 661–673 (2011).
  • Doherty GA, Bennett GC, Cheifetz AS, Moss AC. Meta-analysis: targeting the intestinal microbiota in prophylaxis for post-operative Crohn’s disease. Aliment. Pharmacol. Ther. 31(8), 802–809 (2010).
  • Bernstein LH, Frank MS, Brandt LJ, Boley SJ. Healing of perineal Crohn’s disease with metronidazole. Gastroenterology 79(2), 357–365 (1980).
  • Brandt LJ, Bernstein LH, Boley SJ, Frank MS. Metronidazole therapy for perineal Crohn’s disease: a follow-up study. Gastroenterology 83(2), 383–387 (1982).
  • Jakobovits J, Schuster MM. Metronidazole therapy for Crohn’s disease and associated fistulae. Am. J. Gastroenterol. 79(7), 533–540 (1984).

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