341
Views
10
CrossRef citations to date
0
Altmetric
Perspective

Atypical lymphoid proliferations: the pathologist’s viewpoint

Pages 139-153 | Published online: 10 Jan 2014

References

  • Schratt G, Philippar U, Hockemeyer D, Schwarz H, Alberti S, Nordheim A. SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development. EMBO J. 23(8), 1834–1844 (2004).
  • Hartmann S, Kriener S, Hansmann ML. Diagnostic spectrum of reactive lymph node changes. Pathologe 29(4), 253–263 (2008).
  • Kojima M, Motoori T, Asano S, Nakamura S. Histological diversity of reactive and atypical proliferative lymph node lesions in systemic lupus erythematosus patients. Pathol. Res. Pract. 203(6), 423–431 (2007).
  • Kojima M, Nakamura S, Motoori T et al. Follicular hyperplasia presenting with a marginal zone pattern in a reactive lymph node lesion. APMIS 110(4), 325–331 (2002).
  • Yasuda M, Taura Y, Yokomizo Y, Ekino S. A comparative study of germinal center: fowls and mammals. Comp. Immunol. Microbiol. Infect. Dis. 21(3), 179–189 (1998).
  • Roulland S, Suarez F, Hermine O, Nadel B. Pathophysiological aspects of memory B-cell development. Trends Immunol. 29(1), 25–33 (2008).
  • Smith JP, Burton GF, Tew JG, Szakal AK. Tingible body macrophages in regulation of germinal center reactions. Dev. Immunol. 6(3–4), 285–294 (1998).
  • Förster R, Braun A, Worbs T. Lymph node homing of T cells and dendritic cells via afferent lymphatics. Trends Immunol. 33(6), 271–280 (2012).
  • Fooksman DR, Schwickert TA, Victora GD, Dustin ML, Nussenzweig MC, Skokos D. Development and migration of plasma cells in the mouse lymph node. Immunity 33(1), 118–127 (2010).
  • Gretz JE, Anderson AO, Shaw S. Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex. Immunol. Rev. 156, 11–24 (1997).
  • Good DJ, Gascoyne RD. Atypical lymphoid hyperplasia mimicking lymphoma. Hematol. Oncol. Clin. North Am. 23(4), 729–745 (2009).
  • Czuczman M, Straus D, Gribben J, Bredenfeld H, Friedberg J, Bollard C. Management options, survivorship, and emerging treatment strategies for follicular and Hodgkin lymphomas. Leuk. Lymphoma 51(Suppl. 1), 41–49 (2010).
  • Kojima M, Nakamura S, Shimizu K et al. Reactive lymphoid hyperplasia of the lymph nodes with giant follicles: a clinicopathologic study of 14 Japanese cases, with special reference to Epstein–Barr virus infection. Int. J. Surg. Pathol. 13(3), 267–272 (2005).
  • Abe S. Molecular genetic analysis of malignant lymphoma. Rinsho. Shinkeigaku 42(11), 1124–1126 (2002).
  • Delsol G. Molecular abnormalities in lymphomas. Bull. Cancer 97(11), 1347–1364 (2010).
  • Böer A, Tirumalae R, Bresch M, Falk TM. Pseudoclonality in cutaneous pseudolymphomas: a pitfall in interpretation of rearrangement studies. Br. J. Dermatol. 159(2), 394–402 (2008).
  • Gilliam AC, Wood GS. Cutaneous lymphoid hyperplasias. Semin. Cutan. Med. Surg. 19(2), 133–141 (2000).
  • Carbone A, De Re V, Gloghini A et al. Immunoglobulin and T cell receptor gene rearrangements and in situ immunophenotyping in lymphoproliferative disorders. Virchows Arch. A. Pathol. Anat. Histopathol. 414(3), 223–230 (1989).
  • Henopp T, Quintanilla-Martínez L, Fend F, Adam P. Prevalence of follicular lymphoma in situ in consecutively analysed reactive lymph nodes. Histopathology 59(1), 139–142 (2011).
  • Edlefsen KL, Greisman HA, Yi HS, Mantei KM, Fromm JR. Early lymph node involvement by mantle cell lymphoma limited to the germinal center: report of a case with a novel ‘follicular in situ’ growth pattern. Am. J. Clin. Pathol. 136(2), 276–281 (2011).
  • Roullet MR, Martinez D, Ma L et al. Coexisting follicular and mantle cell lymphoma with each having an in situ component: A novel, curious, and complex consultation case of coincidental, composite, colonizing lymphoma. Am. J. Clin. Pathol. 133(4), 584–591 (2010).
  • Jegalian AG, Eberle FC, Pack SD et al. Follicular lymphoma in situ: clinical implications and comparisons with partial involvement by follicular lymphoma. Blood 118(11), 2976–2984 (2011).
  • Hussein MR, Al-Sabae TM, Georgis MN. Analysis of the Bcl-2 and p53 protein expression in the lymphoproliferative lesions in the upper Egypt. Cancer Biol. Ther. 4(3), 324–328 (2005).
  • Kojima M, Motoori T, Nakamura S. Benign, atypical and malignant lymphoproliferative disorders in rheumatoid arthritis patients. Biomed. Pharmacother. 60(10), 663–672 (2006).
  • Kojima M, Nakamura N, Itoh H et al. Epstein–Barr virus-related atypical lymphoproliferative disorders in Waldeyer’s ring: a clinicopathological study of 9 cases. Pathobiology 77(4), 218–224 (2010).
  • Canioni D, Arnulf B, Asso-Bonnet M, Raphael M, Brousse N. Nasal natural killer lymphoma associated with Epstein–Barr virus in a patient infected with human immunodeficiency virus. Arch. Pathol. Lab. Med. 125(5), 660–662 (2001).
  • Joncas JH, Russo P, Brochu P et al. Epstein–Barr virus polymorphic B-cell lymphoma associated with leukemia and with congenital immunodeficiencies. J. Clin. Oncol. 8(3), 378–384 (1990).
  • Elenitoba-Johnson KS, Jaffe ES. Lymphoproliferative disorders associated with congenital immunodeficiencies. Semin. Diagn. Pathol. 14(1), 35–47 (1997).
  • Ibrahim HA, Menasce LP, Pomplun S, Burke M, Bower M, Naresh KN. Epstein–Barr virus (EBV) genotypes among human immunodeficiency virus (HIV)-related B-cell lymphomas and B-cell post-transplant lymphoproliferative disorders (B-PTLD) – late-onset lymphomas, especially in the HIV setting, are associated with type-B-EBV. Eur. J. Haematol. 85(3), 227–230 (2010).
  • Tiemann M, Asbeck R, Wacker HH. Clonal B-cell reactions and prelymphoma in autoimmune diseases. Verh. Dtsch. Ges. Pathol. 80, 169–177 (1996).
  • Matutes E. Persistent polyclonal B-cell lymphocytosis: benign disease or prelymphoma? Med. Clin. (Barc). 136(13), 578–579 (2011).
  • Lennert K, Schmid U. Prelymphoma, early lymphoma, and manifest lymphoma in immunosialadenitis (Sjögren’s syndrome) – a model of lymphomagenesis. Haematol. Blood Transfus. 28, 418–422 (1983).
  • Indzhiia LV, Iakovleva LA, Kokosha LV, Chepnian ER, Chikobava MG. Imbalance in the immunoregulatory cells and decreased activity of natural killers in a prelymphoma state in baboons. Vestn. Akad. Med. Nauk SSSR 10, 78–82 (1987).
  • Iakovleva LA. Prelymphoma as a stage of malignant lymphoma (baboon malignant lymphoma model). Vopr. Onkol. 54(3), 338–343 (2008).
  • Zhang LY, Lin HY, Gao LX et al. Primary central nervous system plasmablastic lymphoma presenting in human immunodeficiency virus-negative but Epstein–Barr virus-positive patient: a case report. Diagn. Pathol. 7, 51 (2012).
  • Addeo R, Montella L, Baldi A et al. Atypical cutaneous lymphoid hyperplasia induced by chemotherapy in a patient with advanced colon carcinoma. Clin. Colorectal Cancer 6(10), 728–730 (2007).
  • Louissaint A Jr, Ferry JA, Soupir CP, Hasserjian RP, Harris NL, Zukerberg LR. Infectious mononucleosis mimicking lymphoma: distinguishing morphological and immunophenotypic features. Mod. Pathol. 25(8), 1149–1159 (2012).
  • Vasef MA, Alsabeh R, Medeiros LJ, Weiss LM. Immunophenotype of Reed–Sternberg and Hodgkin’s cells in sequential biopsy specimens of Hodgkin’s disease: a paraffin-section immunohistochemical study using the heat-induced epitope retrieval method. Am. J. Clin. Pathol. 108(1), 54–59 (1997).
  • Carbone A, Gloghini A, Dotti G. EBV-associated lymphoproliferative disorders: classification and treatment. Oncologist 13(5), 577–585 (2008).
  • Audouin J, Diebold J, Nathwani B et al. Epstein–Barr virus and Hodgkin’s lymphoma in Cairo, Egypt. J. Hematop. 3(1), 11–18 (2010).
  • Liu Y, Zhu X, Zhuang H et al. Diagnosis and differential diagnosis of nodular lymphocyte-predominant Hodgkin’s lymphoma. Zhonghua Bing Li Xue Za Zhi 31(3), 227–230 (2002).
  • Siddiqui N, Al-Diab AI. Nodular lymphocyte predominant Hodgkin’s lymphoma. Saudi Med. J. 26(2), 241–245 (2005).
  • Kojima M, Motoori T, Hosomura Y, Tanaka H, Sakata N, Masawa N. Atypical lymphoplasmacytic and immunoblastic proliferation from rheumatoid arthritis: a case report. Pathol. Res. Pract. 202(1), 51–54 (2006).
  • Dargent JL, Haller A, Durdurez JP, Gennotte AF. Atypical hyperplasia of the marginal zone of B follicles in a polymorphic Epstein–Barr virus-associated lymphoproliferative disorder occurring in an adolescent with human immunodeficiency virus infection. Pediatr. Dev. Pathol. 12(1), 59–62 (2009).
  • Werner B, Massone C, Kerl H, Cerroni L. Large CD30-positive cells in benign, atypical lymphoid infiltrates of the skin. J. Cutan. Pathol. 35(12), 1100–1107 (2008).
  • Chadburn A, Inghirami G, Knowles DM. The kinetics and temporal expression of T-cell activation-associated antigens CD15 (LeuM1), CD30 (Ki-1), EMA, and CD11c (LeuM5) by benign activated T cells. Hematol. Pathol. 6(4), 193–202 (1992).
  • Cajaiba MM, Kahwash SB. Interfollicular Hodgkin lymphoma in children: an uncommon mimicker of reactive lymphadenopathy. Leuk. Lymphoma 53(9), 1814–1816 (2012).
  • Fellbaum C, Hansmann ML, Lennert K. Lymphadenitis mimicking Hodgkin’s disease. Histopathology 12(3), 253–262 (1988).
  • Vicandi B, Jiménez-Heffernan JA, López-Ferrer P, Gamallo C, Viguer JM. Hodgkin’s disease mimicking suppurative lymphadenitis: a fine-needle aspiration report of five cases. Diagn. Cytopathol. 20(5), 302–306 (1999).
  • Klapper W. Pathobiology and diagnosis of follicular lymphoma. Semin. Diagn. Pathol. 28(2), 146–160 (2011).
  • Freedman A. Follicular lymphoma: 2011 update on diagnosis and management. Am. J. Hematol. 86(9), 768–775 (2011).
  • Hussein MR, Al-Sabae TM, Georgis MN. Analysis of Bcl-2 and p53 protein expression in non-Hodgkin’s lymphoma. Ann. Oncol. 15(12), 1849–1850 (2004).
  • de Leval L, Harris NL, Longtine J, Ferry JA, Duncan LM. Cutaneous B-cell lymphomas of follicular and marginal zone types: use of Bcl-6, CD10, Bcl-2, and CD21 in differential diagnosis and classification. Am. J. Surg. Pathol. 25(6), 732–741 (2001).
  • Schraders M, de Jong D, Kluin P, Groenen P, van Krieken H. Lack of BCL-2 expression in follicular lymphoma may be caused by mutations in the BCL2 gene or by absence of the t(14;18) translocation. J. Pathol. 205(3), 329–335 (2005).
  • Xie JL, Zhou XG, Jin Y et al. Value of loss of CD10 expression in pathologic diagnosis of follicular lymphoma. Zhonghua Bing Li Xue Za Zhi 38(11), 754–758 (2009).
  • Goteri G, Lucarini G, Zizzi A et al. Comparison of germinal center markers CD10, BCL6 and human germinal center-associated lymphoma (HGAL) in follicular lymphomas. Diagn. Pathol. 6, 97 (2011).
  • Weiss LM, Loera S, Bacchi CE. Immunoglobulin light chain immunohistochemistry revisited, with emphasis on reactive follicular hyperplasia versus follicular lymphoma. Appl. Immunohistochem. Mol. Morphol. 18(3), 199–205 (2010).
  • Korac P, Horvat T, Kardum Paro MM, Ajdukovic R, Džebro S, Dominis M. Follicular and mantle cell lymphoma characteristics present simultaneously in the same lymph node. Appl. Immunohistochem. Mol. Morphol. doi:10.1097/PAI.0b013e3182582bd8 (2012) (Epub ahead of print).
  • Carbone A, Gloghini A, Santoro A. In situ follicular lymphoma: pathologic characteristics and diagnostic features. Hematol. Oncol. 30(1), 1–7 (2012).
  • Stacy RC, Jakobiec FA, Schoenfield L, Singh AD. Unifocal and multifocal reactive lymphoid hyperplasia vs follicular lymphoma of the ocular adnexa. Am. J. Ophthalmol. 150(3), 412–426 e2 (2010).
  • Utz GL, Swerdlow SH. Distinction of follicular hyperplasia from follicular lymphoma in B5-fixed tissues: comparison of MT2 and bcl-2 antibodies. Hum. Pathol. 24(11), 1155–1158 (1993).
  • Hu E, Weiss LM, Hoppe RT, Horning SJ. Follicular and diffuse mixed small-cleaved and large-cell lymphoma – a clinicopathologic study. J. Clin. Oncol. 3(9), 1183–1187 (1985).
  • Yih WY, Stewart JC, Kratochvil FJ, Zieper MB. Angiocentric T-cell lymphoma presenting as midface destructive lesion: case report and literature review. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 94(3), 353–360 (2002).
  • Metgud RS, Doshi JJ, Gaurkhede S, Dongre R, Karle R. Extranodal NK/T-cell lymphoma, nasal type (angiocentric T-cell lymphoma): a review about the terminology. J. Oral Maxillofac. Pathol. 15(1), 96–100 (2011).
  • Harning R, Myers C, Merluzzi VJ. Monoclonal antibodies to lymphocyte function-associated antigen-1 inhibit invasion of human lymphoma and metastasis of murine lymphoma. Clin. Exp. Metastasis 11(4), 337–342 (1993).
  • Mitrovic Z, Ilic I, Nola M et al. CD43 expression is an adverse prognostic factor in diffuse large B-cell lymphoma. Clin. Lymphoma Myeloma 9(2), 133–137 (2009).
  • Adam P, Schiefer AI, Prill S et al. Incidence of preclinical manifestations of mantle cell lymphoma and mantle cell lymphoma in situ in reactive lymphoid tissues. Mod. Pathol. 25(12), 1629–1636 (2012).
  • Espinet B, Solé F, Pedro C et al. Clonal proliferation of cyclin D1-positive mantle lymphocytes in an asymptomatic patient: an early-stage event in the development or an indolent form of a mantle cell lymphoma? Hum. Pathol. 36(11), 1232–1237 (2005).
  • Zapata M, Budnick SD, Bordoni R, Li S. An uncommon case of de novo CD10+ CD5- mantle cell lymphoma mimics follicle center B cell lymphoma. Int. J. Clin. Exp. Pathol. 3(4), 430–436 (2010).
  • Tohda S. Overview of lymphoid neoplasms in the fourth edition of the WHO classification. Rinsho Byori. 60(6), 560–564 (2012).
  • Kelemen K, White CR, Gatter K, Braziel RM, Fan G. Immunophenotypic correlation between skin biopsy and peripheral blood findings in mycosis fungoides. Am. J. Clin. Pathol. 134(5), 739–748 (2010).
  • Gulia A, Saggini A, Wiesner T et al. Clinicopathologic features of early lesions of primary cutaneous follicle center lymphoma, diffuse type: implications for early diagnosis and treatment. J. Am. Acad. Dermatol. 65(5), 991–1000 (2011).
  • Ormsby A, Bergfeld WF, Tubbs RR, Hsi ED. Evaluation of a new paraffin-reactive CD7 T-cell deletion marker and a polymerase chain reaction-based T-cell receptor gene rearrangement assay: implications for diagnosis of mycosis fungoides in community clinical practice. J. Am. Acad. Dermatol. 45(3), 405–413 (2001).
  • Cotta AC, Cintra ML, de Souza EM et al. Diagnosis of mycosis fungoides: a comparative immunohistochemical study of T-cell markers using a novel anti-CD7 antibody. Appl. Immunohistochem. Mol. Morphol. 14(3), 291–295 (2006).
  • Bristeau-Leprince A, Mateo V, Lim A et al. Human TCR α/β+ CD4-CD8- double-negative T cells in patients with autoimmune lymphoproliferative syndrome express restricted Vβ TCR diversity and are clonally related to CD8+ T cells. J. Immunol. 181(1), 440–448 (2008).
  • Holzelova E, Vonarbourg C, Stolzenberg MC et al. Autoimmune lymphoproliferative syndrome with somatic Fas mutations. N. Engl. J. Med. 351(14), 1409–1418 (2004).
  • Bugalia A, Manipadam MT, Nair S. Immunomorphologic profile and Epstein–Barr virus status of a cohort of 35 cases of extranodal natural killer/T-cell lymphoma, nasal type of upper aerodigestive tract from a tertiary care center in South India. Leuk. Lymphoma doi:10.3109/10428194.2012.740668 (2012) (Epub ahead of print).
  • Sitthinamsuwan P, Pongpruttipan T, Chularojmontri L, Pattanaprichakul P, Khuhapinant A, Sukpanichnant S. Extranodal NK/T cell lymphoma, nasal type, presenting with primary cutaneous lesion mimicking granulomatous panniculitis: a case report and review of literature. J. Med. Assoc. Thai. 93(8), 1001–1007 (2010).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.