218
Views
8
CrossRef citations to date
0
Altmetric
Theme: Breast Cancer - Review

Breast cancer risk after exposure to fertility drugs

, , , , , , , & show all
Pages 149-157 | Published online: 10 Jan 2014

References

  • Boivin J, Bunting L, Collins JA, Nygren KG. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Hum. Reprod. 22(6), 1506–1512 (2007).
  • Mosher WD, Pratt WF. Fecundity and infertility in the United States: incidence and trends. Fertil. Steril. 56(2), 192–193 (1991).
  • Makar RS, Toth TL. The evaluation of infertility. Am. J. Clin. Pathol. 117(Suppl.), S95–103 (2002).
  • Henne MB, Bundorf MK. Insurance mandates and trends in infertility treatments. Fertil. Steril. 89(1), 66–73 (2008).
  • Wysowski DK. Use of fertility drugs in the United States, 1973 through 1991. Fertil. Steril. 60(6), 1096–1098 (1993).
  • Practice Committee of the American Society for Reproductive Medicine. Use of clomiphene citrate in women. Fertil. Steril. 82(1), 90–96 (2004).
  • Bines J, Oleske DM, Cobleigh MA. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer. J. Clin. Oncol. 14(5), 1718–1729 (1996).
  • Tomao F, Spinelli GP, Panici PB, Frati L, Tomao S. Ovarian function, reproduction and strategies for fertility preservation after breast cancer. Crit. Rev. Oncol. Hematol. 76(1), 1–12 (2010).
  • Lipworth L. Epidemiology of breast cancer. Eur. J. Cancer Prev. 4(1), 7–30 (1995).
  • Bernstein L. Epidemiology of endocrine-related risk factors for breast cancer. J. Mammary Gland Biol. Neoplasia 7(1), 3–15 (2002).
  • Key TJ, Verkasalo PK, Banks E. Epidemiology of breast cancer. Lancet Oncol. 2(3), 133–140 (2001).
  • Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN. Proportion of breast cancer cases in the United States explained by well-established risk factors. J. Natl. Cancer Inst. 87(22), 1681–1685 (1995).
  • Kelsey JL, Gammon MD, John EM. Reproductive factors and breast cancer. Epidemiol. Rev. 15(1), 36–47 (1993).
  • Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53,297 women with breast cancer and 100,239 women without breast cancer from 54 epidemiological studies. Lancet 347(9017), 1713–1727 (1996).
  • Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Lancet 350(9084), 1047–1059 (1997).
  • Kotsopoulos J, Librach CL, Lubinski J et al.; Hereditary Breast Cancer Clinical Study Group. Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case–control study. Cancer Causes Control 19(10), 1111–1119 (2008).
  • Gauthier E, Paoletti X, Clavel-Chapelon F; E3N group. Breast cancer risk associated with being treated for infertility: results from the French E3N cohort study. Hum. Reprod. 19(10), 2216–2221 (2004).
  • Doyle P, Maconochie N, Beral V, Swerdlow AJ, Tan SL. Cancer incidence following treatment for infertility at a clinic in the UK. Hum. Reprod. 17(8), 2209–2213 (2002).
  • Potashnik G, Lerner-Geva L, Genkin L, Chetrit A, Lunenfeld E, Porath A. Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study. Fertil. Steril. 71(5), 853–859 (1999).
  • Silva Idos S, Wark PA, McCormack VA et al. Ovulation-stimulation drugs and cancer risks: a long-term follow-up of a British cohort. Br. J. Cancer 100(11), 1824–1831 (2009).
  • Braga C, Negri E, La Vecchia C, Parazzini F, Dal Maso L, Franceschi S. Fertility treatment and risk of breast cancer. Hum. Reprod. 11(2), 300–303 (1996).
  • Modan B, Ron E, Lerner-Geva L et al. Cancer incidence in a cohort of infertile women. Am. J. Epidemiol. 147(11), 1038–1042 (1998).
  • Ricci E, Parazzini F, Negri E, Marsico S, La Vecchia C. Fertility drugs and the risk of breast cancer. Hum. Reprod. 14(6), 1653–1655 (1999).
  • Bernstein L, Hanisch R, Sullivan-Halley J, Ross RK. Treatment with human chorionic gonadotropin and risk of breast cancer. Cancer Epidemiol. Biomarkers Prev. 4(5), 437–440 (1995).
  • Jensen A, Sharif H, Svare EI, Frederiksen K, Kjaer SK. Risk of breast cancer after exposure to fertility drugs: results from a large Danish cohort study. Cancer Epidemiol. Biomarkers Prev. 16(7), 1400–1407 (2007).
  • Burkman RT, Tang MT, Malone KE et al. Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human Development Women’s Contraceptive and Reproductive Experiences Study. Fertil. Steril. 79(4), 844–851 (2003).
  • Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG. Risk of breast cancer in a cohort of infertile women. Gynecol. Oncol. 60(1), 3–7 (1996).
  • Terry KL, Willett WC, Rich-Edwards JW, Michels KB. A prospective study of infertility due to ovulatory disorders, ovulation induction, and incidence of breast cancer. Arch. Intern. Med. 166(22), 2484–2489 (2006).
  • Brinton LA, Scoccia B, Moghissi KS et al. Breast cancer risk associated with ovulation-stimulating drugs. Hum. Reprod. 19(9), 2005–2013 (2004).
  • Lerner-Geva L, Keinan-Boker L, Blumstein T et al. Infertility, ovulation induction treatments and the incidence of breast cancer – a historical prospective cohort of Israeli women. Breast Cancer Res. Treat. 100(2), 201–212 (2006).
  • Calderon-Margalit R, Friedlander Y, Yanetz R et al. Cancer risk after exposure to treatments for ovulation induction. Am. J. Epidemiol. 169(3), 365–375 (2009).
  • Orgéas CC, Sanner K, Hall P et al. Breast cancer incidence after hormonal infertility treatment in Sweden: a cohort study. Am. J. Obstet. Gynecol. 200(1), 72.e1–72.e7 (2009).
  • Fei C, Deroo LA, Sandler DP, Weinberg CR. Fertility drugs and young-onset breast cancer: results from the Two Sister Study. J. Natl. Cancer Inst. 104(13), 1021–1027 (2012).
  • Lerner-Geva L, Geva E, Lessing JB, Chetrit A, Modan B, Amit A. The possible association between in vitro fertilization treatments and cancer development. Int. J. Gynecol. Cancer 13(1), 23–27 (2003).
  • Dor J, Lerner-Geva L, Rabinovici J et al. Cancer incidence in a cohort of infertile women who underwent in vitro fertilization. Fertil. Steril. 77(2), 324–327 (2002).
  • Venn A, Watson L, Bruinsma F, Giles G, Healy D. Risk of cancer after use of fertility drugs with in-vitro fertilisation. Lancet 354(9190), 1586–1590 (1999).
  • Brzezinski A, Peretz T, Mor-Yosef S, Schenker JG. Ovarian stimulation and breast cancer: is there a link? Gynecol. Oncol. 52(3), 292–295 (1994).
  • Venn A, Watson L, Lumley J, Giles G, King C, Healy D. Breast and ovarian cancer incidence after infertility and in vitro fertilisation. Lancet 346(8981), 995–1000 (1995).
  • Jourdain O, Avril A, Mauriac L et al. Breast cancer and in vitro fertilization. About 32 cases. Eur. J. Obstet. Gynecol. Reprod. Biol. 67(1), 47–52 (1996).
  • Kristiansson P, Björ O, Wramsby H. Tumour incidence in Swedish women who gave birth following IVF treatment. Hum. Reprod. 22(2), 421–426 (2007).
  • Katz D, Paltiel O, Peretz T et al. Beginning IVF treatments after age 30 increases the risk of breast cancer: results of a case–control study. Breast J. 14(6), 517–522 (2008).
  • Pappo I, Lerner-Geva L, Halevy A et al. The possible association between IVF and breast cancer incidence. Ann. Surg. Oncol. 15(4), 1048–1055 (2008).
  • Källén B, Finnström O, Lindam A, Nilsson E, Nygren KG, Olausson PO. Malignancies among women who gave birth after in vitro fertilization. Hum. Reprod. 26(1), 253–258 (2011).
  • Zreik TG, Mazloom A, Chen Y et al. Fertility drugs and the risk of breast cancer: a meta-analysis and review. Breast Cancer Res. Treat. 124(1), 13–26 (2010).
  • GoldsteinSR, SiddhantiS, CiacciaAV, PlouffeL Jr. A pharmacological review of selective oestrogen receptor modulators. Hum. Reprod. Update 6(3), 212–224 (2000).
  • Sovino H, Sir-Petermann T, Devoto L. Clomiphene citrate and ovulation induction. Reprod. Biomed. Online 4(3), 303–310 (2002).
  • Henderson BE, Ross RK, Judd HL, Krailo MD, Pike MC. Do regular ovulatory cycles increase breast cancer risk? Cancer 56(5), 1206–1208 (1985).
  • Cowan LD, Gordis L, Tonascia JA, Jones GS. Breast cancer incidence in women with a history of progesterone deficiency. Am. J. Epidemiol. 114(2), 209–217 (1981).
  • Bolton PM. Bilateral breast cancer associated with clomiphene. Lancet 2(8049), 1176 (1977).
  • Richards JF, Griffith DR. Effect of cis-and trans-clomiphene on mammary gland development in the rat. Fertil. Steril. 25(1), 74–78 (1974).
  • Sutherland RL, Watts CK, Hall RE, Ruenitz PC. Mechanisms of growth inhibition by nonsteroidal antioestrogens in human breast cancer cells. J. Steroid Biochem. 27(4–6), 891–897 (1987).
  • Murphy LC, Sutherland RL. Antitumor activity of clomiphene analogs in vitro: relationship to affinity for the estrogen receptor and another high affinity antiestrogen-binding site. J. Clin. Endocrinol. Metab. 57(2), 373–379 (1983).
  • Fisher B, Costantino JP, Wickerham DL et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J. Natl. Cancer Inst. 90(18), 1371–1388 (1998).
  • Lerner LJ, Jordan VC. Development of antiestrogens and their use in breast cancer: eighth Cain memorial award lecture. Cancer Res. 50(14), 4177–4189 (1990).
  • Hecker E, Vegh I, Levy CM et al. Clinical trial of clomiphene in advanced breast cancer. Eur. J. Cancer 10(11), 747–749 (1974).
  • Coulam CB, Annegers JF, Kranz JS. Chronic anovulation syndrome and associated neoplasia. Obstet. Gynecol. 61(4), 403–407 (1983).
  • Ron E, Lunenfeld B, Menczer J et al. Cancer incidence in a cohort of infertile women. Am. J. Epidemiol. 125(5), 780–790 (1987).
  • Gammon MD, Thompson WD. Infertility and breast cancer: a population-based case–control study. Am. J. Epidemiol. 132(4), 708–716 (1990).
  • Brinton LA, Melton LJ 3rd, Malkasian GD Jr, Bond A, Hoover R. Cancer risk after evaluation for infertility. Am. J. Epidemiol. 129(4), 712–722 (1989).
  • Weiss HA, Troisi R, Rossing MA et al. Fertility problems and breast cancer risk in young women: a case–control study in the United States. Cancer Causes Control 9(3), 331–339 (1998).
  • Gips H, Hormel P, Hinz V. Ovarian stimulation in assisted reproduction. Andrologia 28(Suppl. 1), 3–7 (1996).
  • Diedrich K, Felberbaum R. New approaches to ovarian stimulation. Hum. Reprod. 13(Suppl. 3), 1–13; discussion 14 (1998).
  • Leibowitz D, Hoffman J. Fertility drug therapies: past, present, and future. J. Obstet. Gynecol. Neonatal Nurs. 29(2), 201–210 (2000).
  • Holzer H, Casper R, Tulandi T. A new era in ovulation induction. Fertil. Steril. 85(2), 277–284 (2006).
  • Jennings JC, Moreland K, Peterson CM. In vitro fertilisation. A review of drug therapy and clinical management. Drugs 52(3), 313–343 (1996).
  • Check JH, Slovis B. Choosing the right stimulation protocol for in vitro fertilization-embryo transfer in poor, normal, and hyper-responders. Clin. Exp. Obstet. Gynecol. 38(4), 313–317 (2011).
  • Zarek SM, Muasher SJ. Mild/minimal stimulation for in vitro fertilization: an old idea that needs to be revisited. Fertil. Steril. 95(8), 2449–2455 (2011).
  • Oehninger S. Ovulation induction in IVF. Minerva Ginecol. 63(2), 137–156 (2011).
  • Al-Inany HG, Youssef MA, Aboulghar M et al. Gonadotrophin-releasing hormone antagonists for assisted reproductive technology. Cochrane Database Syst. Rev. 5, CD001750 (2011).
  • Kolibianakis EM, Tarlatzis B, Devroey P. GnRH antagonists in IVF. Reprod. Biomed. Online 10(6), 705–712 (2005).
  • Venn A, Hemminki E, Watson L, Bruinsma F, Healy D. Mortality in a cohort of IVF patients. Hum. Reprod. 16(12), 2691–2696 (2001).
  • Källén B, Finnström O, Nygren KG, Otterblad Olausson P, Wennerholm UB. In vitro fertilisation in Sweden: obstetric characteristics, maternal morbidity and mortality. BJOG 112(11), 1529–1535 (2005).
  • Impicciatore GG, Tiboni GM. Ovulation inducing agents and cancer risk: review of literature. Curr. Drug Saf. 6(4), 250–258 (2011).
  • Cetin I, Cozzi V, Antonazzo P. Infertility as a cancer risk factor – a review. Placenta 29(Suppl. B), 169–177 (2008).
  • Brinton LA, Sahasrabuddhe VV, Scoccia B. Fertility drugs and the risk of breast and gynecologic cancers. Semin. Reprod. Med. 30(2), 131–145 (2012).
  • Papanikolaou EG, Polyzos NP, Humaidan P et al. Aromatase inhibitors in stimulated IVF cycles. Reprod. Biol. Endocrinol. 9, 85 (2011).
  • Fouda UM, Sayed AM. Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial. Reprod. Biol. Endocrinol. 9, 84 (2011).
  • Casper RF. Aromatase inhibitors in ovarian stimulation. J. Steroid Biochem. Mol. Biol. 106(1–5), 71–75 (2007).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.