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Review

Cardiovascular disease risk reduction with sleep apnea treatment

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Pages 995-1005 | Published online: 10 Jan 2014

References

  • National Commission on Sleep Disorders Research. The National Commission on Sleep Disorders Research. Wake up America: a national sleep alert. US Government Printing Office, Washington DC, USA (2008).
  • Shahar E, Whitney CW, Redline S et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am. J. Respir. Crit. Care Med.163(1), 19–25 (2001).
  • Mehra R, Benjamin EJ, Shahar E et al. Association of nocturnal arrhythmias with sleep-disordered breathing: the Sleep Heart Health Study. Am. J. Respir. Crit. Care Med.173(8), 910–916 (2006).
  • Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea–hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet365(9464), 1046–1053 (2005).
  • Hung J, Whitford EG, Parsons RW, Hillman DR. Association of sleep apnoea with myocardial infarction in men. Lancet336(8710), 261–264 (1990).
  • Valham F, Mooe T, Rabben T, Stenlund H, Wiklund U, Franklin KA. Increased risk of stroke in patients with coronary artery disease and sleep apnea: a 10-year follow-up. Circulation118(9), 955–960 (2008).
  • Somers VK, White DP, Amin R et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J. Am. Coll. Cardiol.52(8), 686–717 (2008).
  • Coccagna G, Mantovani M, Brignani F, Parchi C, Lugaresi E. Tracheostomy in hypersomnia with periodic breathing. Bull. Physiopathol. Respir. (Nancy)8(5), 1217–1227 (1972).
  • Coccagna G, Mantovani M, Brignani F, Parchi C, Lugaresi E. Continuous recording of the pulmonary and systemic arterial pressure during sleep in syndromes of hypersomnia with periodic breathing. Bull. Physiopathol. Respir.(Nancy)8(5), 1159–1172 (1972).
  • Stoohs RA, Guilleminault C, Itoi A, Dement WC. Traffic accidents in commercial long-haul truck drivers: the influence of sleep-disordered breathing and obesity. Sleep17(7), 619–623 (1994).
  • El Ad B, Lavie P. Effect of sleep apnea on cognition and mood. Int. Rev. Psychiatry17(4), 277–282 (2005).
  • Sharafkhaneh A, Giray N, Richardson P, Young T, Hirshkowitz M. Association of psychiatric disorders and sleep apnea in a large cohort. Sleep28(11), 1405–1411 (2005).
  • Punjabi NM, Caffo BS, Goodwin JL et al. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med.6(8), e1000132 (2009).
  • Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive sleep apnea as a risk factor for stroke and death. N. Engl. J. Med.353(19), 2034–2041 (2005).
  • Aartz M, Young T, Finn L, Skatrud JB, Bradley D. Association of sleep-disordered breathing and the occurence of stroke. Am. J. Respir. Crit. Care Med.172, 1447–1451 (2005).
  • Lavie P, Lavie L, Herer P. All-cause mortality in males with sleep apnoea syndrome: declining mortality rates with age. Eur. Respir. J.25(3), 514–520 (2005).
  • Gami AS, Pressman G, Caples SM. Association of atrial fibrillation and obstructive sleep apnea. Circulation27(364), 364–367 (2004).
  • Kiely JL, McNicholas WT, Zgierska A et al. Cardiovascular risk factors in patients with obstructive sleep apnoea syndrome. Eur. Respir. J.16(1), 128–133 (2000).
  • Bradley TD, Floras JS. Obstructive sleep apnoea and its cardiovascular consequences. Lancet373(9657), 82–93 (2009).
  • Shepard JW Jr, Garrison MW, Grither DA, Evans R, Schweitzer PK. Relationship of ventricular ectopy to nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease. Am. J. Med.78(1), 28–34 (1985).
  • Shamsuzzaman AS, Gersh BJ, Somers VK. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA290(14), 1906–1914 (2003).
  • Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J. Clin. Invest96(4), 1897–1904 (1995).
  • Dyken ME, Somers VK, Yamada T, Ren ZY, Zimmerman MB. Investigating the relationship between stroke and obstructive sleep apnea. Stroke27(3), 401–407 (1996).
  • Sanner BM, Konermann M, Tepel M, Groetz J, Mummenhoff C, Zidek W. Platelet function in patients with obstructive sleep apnoea syndrome. Eur. Respir. J.16(4), 648–652 (2000).
  • Franklin KA, Nilsson JB, Sahlin C, Naslund U. Sleep apnoea and nocturnal angina. Lancet345(8957), 1085–1087 (1995).
  • Bradley TD. Right and left ventricular functional impairment and sleep apnea. Clin. Chest Med.13(3), 459–479 (1992).
  • Lavie L. Obstructive sleep apnoea syndrome – an oxidative stress disorder. Sleep Med. Rev.7(1), 35–51 (2003).
  • Kasasbeh E, Chi DS, Krishnaswamy G. Inflammatory aspects of sleep apnea and their cardiovascular consequences. South Med. J.99(1), 58–67 (2006).
  • Ip MS, Lam B, Chan LY et al. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am. J. Respir. Crit. Care Med.162(6), 2166–2171 (2000).
  • von Kanel R, Loredo JS, Powell FL, Adler KA, Dimsdale JE. Short-term isocapnic hypoxia and coagulation activation in patients with sleep apnea. Clin. Hemorheol. Microcirc.33(4), 369–377 (2005).
  • Mills PJ, von Kanel R, Norman D, Natarajan L, Ziegler MG, Dimsdale JE. Inflammation and sleep in healthy individuals. Sleep30(6), 729–735 (2007).
  • Young T, Finn L. Epidemiological insights into the public health burden of sleep disordered breathing: sex differences in survival among sleep clinic patients. Thorax53(Suppl. 3), S16–S19 (1998).
  • Young T, Peppard P, Palta M et al. Population-based study of sleep-disordered breathing as a risk factor for hypertension. Arch. Intern. Med.157(15), 1746–1752 (1997).
  • Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N. Engl. J. Med.328(17), 1230–1235 (1993).
  • Remmers JE, Launois S, Feroah T, Whitelaw WA. Mechanics of the pharynx in patients with obstructive sleep apnea. Prog. Clin. Biol. Res.345, 261–268 (1990).
  • Guilleminault C, Tilkian A, Dement WC. The sleep apnea syndromes. Annu. Rev. Med.27(465), 465–484 (1976).
  • Rechtshaffen A, Kales A. A manual of standardized terminology, techniques, and scoring systems of sleep stages of human subjects. UCLA Brain Information Service/Brain Research Institute, Los Angeles, USA (1968).
  • Chesson AL Jr, Ferber RA, Fry JM et al. The indications for polysomnography and related procedures. Sleep20(6), 423–487 (1997).
  • Principles and Practice of Sleep Medicine. Kryger M, Roth T, Dement W (Eds). WB Saunders Co., PA, USA, 1–1336 (2002).
  • Giles TL, Lasserson TJ, Smith BH, White J, Wright J, Cates CJ. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst. Rev.3, CD001106 (2006).
  • Stepnowsky CJ, Palau JJ, Gifford AL, Ancoli-Israel S. A self-management approach to improving continuous positive airway pressure adherence and outcomes. Behav. Sleep Med.5(2), 131–146 (2007).
  • Strobel RJ, Rosen RC. Obesity and weight loss in obstructive sleep apnea: a critical review. Sleep19(2), 104–115 (1996).
  • Malone S, Liu PP, Holloway R, Rutherford R, Xie A, Bradley TD. Obstructive sleep apnoea in patients with dilated cardiomyopathy: effects of continuous positive airway pressure. Lancet338(8781), 1480–1484 (1991).
  • Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J. Clin. Invest.96(4), 1897–1904 (1995).
  • Buchner NJ, Sanner BM, Borgel J, Rump LC. Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk. Am. J. Respir. Crit. Care Med.176(12), 1274–1280 (2007).
  • Doherty LS, Kiely JL, Swan V, McNicholas WT. Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome. Chest127(6), 2076–2084 (2005).
  • Ohike Y, Kozaki K, Iijima K et al. Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure – possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine. Circ. J.69(2), 221–226 (2005).
  • Yokoe T, Minoguchi K, Matsuo H et al. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation107(8), 1129–1134 (2003).
  • Ryan S, Taylor CT, McNicholas WT. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation112(17), 2660–2667 (2005).
  • Dorkova Z, Petrasova D, Molcanyiova A, Popovnakova M, Tkacova R. Effects of continuous positive airway pressure on cardiovascular risk profile in patients with severe obstructive sleep apnea and metabolic syndrome. Chest134(4), 686–692 (2008).
  • Schulz R, Schmidt D, Blum A et al. Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy. Thorax55(12), 1046–1051 (2000).
  • Tasali E, Ip MS. Obstructive sleep apnea and metabolic syndrome: alterations in glucose metabolism and inflammation. Proc. Am. Thorac. Soc.5(2), 207–217 (2008).
  • Vgontzas AN, Papanicolaou DA, Bixler EO et al. Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia. J. Clin. Endocrinol. Metab.85(3), 1151–1158 (2000).
  • Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care28(11), 2745–2749 (2005).
  • Alberti KG, Eckel RH, Grundy SM et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation120(16), 1640–1645 (2009).
  • Grundy SM. A constellation of complications: the metabolic syndrome. Clin. Cornerstone7(2–3), 36–45 (2005).
  • Alexander CM. The coming of age of the metabolic syndrome. Diabetes Care26(11), 3180–3181 (2003).
  • Parish JM, Adam T, Facchiano L. Relationship of metabolic syndrome and obstructive sleep apnea. J. Clin. Sleep Med.3(5), 467–472 (2007).
  • Ambrosetti M, Lucioni AM, Conti S, Pedretti RF, Neri M. Metabolic syndrome in obstructive sleep apnea and related cardiovascular risk. J. Cardiovasc. Med. (Hagerstown)7(11), 826–829 (2006).
  • Drager LF, Bortolotto LA, Maki-Nunes C et al. The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome. Atherosclerosis208(2), 490–495 (2010).
  • Oktay B, Akbal E, Firat H, Ardic S, Kizilgun M. CPAP treatment in the coexistence of obstructive sleep apnea syndrome and metabolic syndrome, results of one year follow up. Acta Clin. Belg.64(4), 329–334 (2009).
  • Grunstein R, Wilcox I, Yang TS, Gould Y, Hedner J. Snoring and sleep apnoea in men: association with central obesity and hypertension. Int. J. Obes. Relat. Metab. Disord.17(9), 533–540 (1993).
  • Kushida CA, Efron B, Guilleminault C. A predictive morphometric model for the obstructive sleep apnea syndrome. Ann. Intern. Med.127(8 Pt 1), 581–587 (1997).
  • Punjabi NM, Sorkin JD, Katzel LI, Goldberg AP, Schwartz AR, Smith PL. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am. J. Respir. Crit. Care Med.165(5), 677–682 (2002).
  • Peppard PE, Young T, Palta M, Dempsey J, Skatrud J. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA284(23), 3015–3021 (2000).
  • Dixon JB, Schachter LM, O’Brien PE. Polysomnography before and after weight loss in obese patients with severe sleep apnea. Int. J. Obes. (Lond.)29(9), 1048–1054 (2005).
  • Rao A, Tey BH, Ramalingam G, Poh AG. Obstructive sleep apnoea (OSA) patterns in bariatric surgical practice and response of OSA to weight loss after laparoscopic adjustable gastric banding (LAGB). Ann. Acad. Med. Singapore38(7), 587–587 (2009).
  • Cunneen SA. Review of meta-analytic comparisons of bariatric surgery with a focus on laparoscopic adjustable gastric banding. Surg. Obes. Relat Dis.4(3 Suppl.), S47–S55 (2008).
  • Redenius R, Murphy C, O’Neill E, Al Hamwi M, Zallek SN. Does CPAP lead to change in BMI? J. Clin. Sleep Med.4(3), 205–209 (2008).
  • Kajaste S, Brander PE, Telakivi T, Partinen M, Mustajoki P. A cognitive-behavioral weight reduction program in the treatment of obstructive sleep apnea syndrome with or without initial nasal CPAP: a randomized study. Sleep Med.5(2), 125–131 (2004).
  • Marcus DM, Lynn J, Miller JJ, Chaudhary O, Thomas D, Chaudhary B. Sleep disorders: a risk factor for pseudotumor cerebri? J. Neuroophthalmol.21(2), 121–123 (2001).
  • Lavie P, Herer P, Hoffstein V. Obstructive sleep apnoea syndrome as a risk factor for hypertension: population study. Br. Med. J.320(7233), 479–482 (2000).
  • Ohayon MM, Guilleminault C, Priest RG, Zulley J, Smirne S. Is sleep-disordered breathing an independent risk factor for hypertension in the general population (13,057 subjects)? J. Psychosom. Res.48(6), 593–601 (2000).
  • Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N. Engl. J. Med.342(19), 1378–1384 (2000).
  • Kaneko Y, Floras JS, Usui K et al. Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea. N. Engl. J. Med.348(13), 1233–1241 (2003).
  • Mayer J, Becker H, Brandenburg U, Penzel T, Peter JH, von Wichert P. Blood pressure and sleep apnea: results of long-term nasal continuous positive airway pressure therapy. Cardiology79(2), 84–92 (1991).
  • Coughlin SR, Mawdsley L, Mugarza JA, Wilding JP, Calverley PM. Cardiovascular and metabolic effects of CPAP in obese males with OSA. Eur. Respir. J.29(4), 720–727 (2007).
  • Duran-Cantolla J, Aizpuru F, Martinez-Null C, Barbe-Illa F. Obstructive sleep apnea/hypopnea and systemic hypertension. Sleep Med. Rev.13(5), 323–331 (2009).
  • Alajmi M, Mulgrew AT, Fox J et al. Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea: a meta-analysis of randomized controlled trials. Lung185(2), 67–72 (2007).
  • Harris MI. Diabetes in America: epidemiology and scope of the problem. Diabetes Care21(Suppl. 3), C11–C14 (1998).
  • Vgontzas AN, Bixler EO, Chrousos GP. Metabolic disturbances in obesity versus sleep apnoea: the importance of visceral obesity and insulin resistance. J. Intern.Med.254(1), 32–44 (2003).
  • Punjabi NM, Polotsky VY. Disorders of glucose metabolism in sleep apnea. J. Appl. Physiol.99(5), 1998–2007 (2005).
  • Punjabi NM, Ahmed MM, Polotsky VY, Beamer BA, O’Donnell CP. Sleep-disordered breathing, glucose intolerance, and insulin resistance. Respir. Physiol. Neurobiol.136(2–3), 167–178 (2003).
  • Punjabi NM, Shahar E, Redline S, Gottlieb DJ, Givelber R, Resnick HE. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am. J. Epidemiol.160(6), 521–530 (2004).
  • Lam JC, Lam B, Yao TJ et al. A randomised controlled trial of nasal continuous positive airway pressure on insulin sensitivity in obstructive sleep apnoea. Eur. Respir. J.35(1), 138–145 (2010).
  • Dawson A, Abel SL, Loving RT et al. CPAP therapy of obstructive sleep apnea in Type 2 diabetics improves glycemic control during sleep. J. Clin. Sleep Med.4(6), 538–542 (2008).
  • Babu AR, Herdegen J, Fogelfeld L, Shott S, Mazzone T. Type 2 diabetes, glycemic control, and continuous positive airway pressure in obstructive sleep apnea. Arch. Intern. Med.165(4), 447–452 (2005).
  • Cuhadaroglu C, Utkusavas A, Ozturk L, Salman S, Ece T. Effects of nasal CPAP treatment on insulin resistance, lipid profile, and plasma leptin in sleep apnea. Lung187(2), 75–81 (2009).
  • Stamler J, Wentworth D, Neaton JD. Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT). JAMA256(20), 2823–2828 (1986).
  • Goff DC Jr, D’Agostino RB Jr, Haffner SM, Otvos JD. Insulin resistance and adiposity influence lipoprotein size and subclass concentrations. Results from the Insulin Resistance Atherosclerosis Study. Metabolism54(2), 264–270 (2005).
  • Tan KC, Chow WS, Lam JC et al. HDL dysfunction in obstructive sleep apnea. Atherosclerosis184(2), 377–382 (2006).
  • Borgel J, Sanner BM, Bittlinsky A et al Obstructive sleep apnoea and its therapy influence high-density lipoprotein cholesterol serum levels. Eur. Respir. J.27(1), 121–127 (2006).
  • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA285(19), 2486–2497 (2001).
  • Brown G, Albers JJ, Fisher LD et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N. Engl. J. Med.323(19), 1289–1298 (1990).
  • Lee PY, Yun AJ, Bazar KA. Acute coronary syndromes and heart failure may reflect maladaptations of trauma physiology that was shaped during pre-modern evolution. Med. Hypotheses62(6), 861–867 (2004).
  • Fletcher EC. Cardiovascular disease associated with obstructive sleep apnea. Monaldi Arch. Chest Dis.59(3), 254–261 (2003).
  • Mansfield DR, Gollogly NC, Kaye DM, Richardson M, Bergin P, Naughton MT. Controlled trial of continuous positive airway pressure in obstructive sleep apnea and heart failure. Am. J. Respir. Crit. Care Med.169(3), 361–366 (2004).
  • Milleron O, Pilliere R, Foucher A et al. Benefits of obstructive sleep apnoea treatment in coronary artery disease: a long-term follow-up study. Eur. Heart J.25(9), 728–734 (2004).
  • Sajkov D, Wang T, Saunders NA, Bune AJ, Neill AM, Douglas MR. Daytime pulmonary hemodynamics in patients with obstructive sleep apnea without lung disease. Am. J. Respir. Crit. Care Med.159(5 Pt 1), 1518–1526 (1999).
  • Harsch IA, Hahn EG, Konturek PC. Insulin resistance and other metabolic aspects of the obstructive sleep apnea syndrome. Med. Sci. Monit.11(3), RA70–RA75 (2005).
  • Eastwood PR, Malhotra A, Palmer LJ et al. Obstructive sleep apnoea: from pathogenesis to treatment: current controversies and future directions. Respirology15(4), 587–595 (2010).
  • Sanner M, Ko N, Oberauemr C, Thomaws EBS, Walzide KM. Sleep-disordered breathing in patients referred for angina evaluation – association with left ventricular dysfunction. Clin. Cardiol.24, 146–150 (2001).
  • Schäfer H, Koehler U, Ewig S, Hasper E, Tasci S, Lüderitz B. Obstructive sleep apnea as a risk marker in coronary artery disease. Cardiology92(2), 79–84 (1999).
  • Einhorn D, Stewart DA, Erman MK, Gordon N, Philis-Tsimikas A, Casal E. Prevalence of sleep apnea in a population of adults with Type 2 diabetes mellitus. Endocr. Pract.13(4), 355–362 (2007).
  • Sjöström C, Lindberg E, Elmasry A, Hägg A, Svärdsudd K, Janson C. Prevalence of sleep apnoea and snoring in hypertensive men: a population based study. Thorax57(7), 602–607 (2002).
  • Gami AS, Pressman G, Caples SM et al. Association of atrial fibrillation and obstructive sleep apnea. Circulation110, 364–367 (2004).
  • Javaheri S, Storfer-Isser A, Rosen CL, Redline S. Sleep quality and elevated blood pressure in adolescents. Circulation118(10), 1034–1040 (2008).
  • Logan AG, Perlikowski SM, Mente A et al. High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J. Hypertens.19(12), 2271–2277 (2001).

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