Design properties of hydrogel tissue-engineering scaffolds

References

• Kopecek J. Hydrogel biomaterials: a smart future? Biomaterials28(34), 5185–5192 (2007).
   PubMed Web of Science ®Google Scholar
• Lutolf MP. Biomaterials: Spotlight on hydrogels. Nat. Mater.8(6), 451–453 (2009).
   PubMed Web of Science ®Google Scholar
• Chung HK, Park TG. Self-assembled and nanostructured hydrogels for drug delivery and tissue engineering. Nano Today4(5), 429–437 (2009).
   Web of Science ®Google Scholar
• Oh JK. Engineering of nanometer-sized cross-linked hydrogels for biomedical applications. Can. J. Chem.88(3), 173–184 (2010).
   Web of Science ®Google Scholar
• Ulijn RV, Bibi N, Jayawarna V et al. Bioresponsive hydrogels. Mater. Today10(4), 40–48 (2007).
   Web of Science ®Google Scholar
• Lee J, Cuddihy MJ, Kotov NA. Three-dimensional cell culture matrices: state of the art. Tissue. Eng. Part B14(1), 61–86 (2008)
   PubMed Web of Science ®Google Scholar
• Zhu J. Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering. Biomaterials31(17), 4639–4656 (2010).
   PubMed Web of Science ®Google Scholar
• Geckil H, Xu F, Zhang XH, Moon S, Demirici U. Engineering hydrogels as extracellular matrix mimics. Nanomedicine5(3), 469–484 (2010).
   PubMed Web of Science ®Google Scholar
• Hunt NC, Grover LM. Cell encapsulation using biopolymer gels for regenerative medicine. Biotechnol. Lett.32(6), 733–742 (2010).
   PubMed Web of Science ®Google Scholar
• Drury JL, Mooney DJ. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials24(24), 4337–4351 (2003).
   PubMed Web of Science ®Google Scholar
• Liu SQ, Tay R, Khan M, Ee PLR, Hedrick JL, Yang YY. Synthetic hydrogels for controlled stem cell differentiation. Soft Matter6(1), 67–81 (2010).
   Web of Science ®Google Scholar
• Slaughter BV, Khurshid SS, Fisher OZ, Khademhosseini A, Peppas NA. Hydrogels in regenerative medicine. Adv. Mater.21(32–33), 3307–3329 (2009).
   PubMed Web of Science ®Google Scholar
• Nicodemus GD, Bryant SJ. Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng. Part B Rev.14(2), 149–165 (2008).
   PubMed Web of Science ®Google Scholar
• Cushing MC, Anseth KS. Hydrogel cell culture. Science316(5828), 1133–1134 (2007).
   PubMed Web of Science ®Google Scholar
• Nuttelman CR, Rice MA, Rydholm AE, Salinas CN, Shah DN, Anseth KS. Macromolecular monomers for the synthesis of hydrogel niches and their application in cell encapsulation and tissue engineering. Prog. Polym. Sci.33(2), 167–170 (2008).
   PubMed Web of Science ®Google Scholar
• Brandl F, Sommer F, Goepferich A. Rational design of hydrogels for tissue engineering: Impact of physical factors on cell behavior. Biomaterials28(2), 134–146 (2007).
   PubMed Web of Science ®Google Scholar
• Varghese S, Elisseeff JH. Hydrogels for musculoskeletal tissue engineering. Adv. Polym. Sci.203, 95–144 (2006).
   Web of Science ®Google Scholar
• Tan H, Marra KG. Injectable, biodegradable hydrogels for tissue engineering applications. Materials3, 1746–1767 (2010).
   Web of Science ®Google Scholar
• Kretlow JD, Klouda L, Mikos AG. Injectable matrices and scaffolds for drug delivery in tissue engineering. Adv. Drug Deliver. Rev.59(4–5), 263–273 (2007).
   PubMed Web of Science ®Google Scholar
• Ifkovits JL, Burdick JA. Review: photopolymerizable and degradable biomaterials for tissue engineering applications. Tissue Eng.13(10), 2369–2385 (2007).
   PubMedGoogle Scholar
• Nguyen TK, West JL. Photopolymerizable hydrogels for tissue engineering applications. Biomaterials23(22), 4307–4314 (2002).
   PubMed Web of Science ®Google Scholar
• Hoffman AS. Hydrogels for biomedical applications. Adv. Drug Deliver. Rev.43(1), 3–12 (2002).
   Web of Science ®Google Scholar
• Lin CC, Metters AT. Hydrogels in controlled release formulations: network design and mathematical modeling. Adv. Drug Deliver. Rev.58(12–13), 1379–1408 (2006).
   PubMed Web of Science ®Google Scholar
• Peppas NA, Huang Y, Torres-Lugo M, Ward JH, Zhang J. Physicochemical foundations and structural design of hydrogels in medicine and biology. Annu. Rev. Biomed. Eng.2, 9–29 (2000).
   PubMed Web of Science ®Google Scholar
• Peppas NA, Hilt JZ, Khademhosseini A, Langer R. Hydrogels in biology and medicine: From Molecular principles to bionanotechnology. Adv. Mater.18(11), 1345–1360 (2006).
   Web of Science ®Google Scholar
• Deiber JA, Ottone ML, Piaggio MV, Peirotti MB. Characterization of cross-linked polyampholytic gelatin hydrogels through the rubber elasticity and thermodynamic theories. Polymer50(25), 6065–6075 (2009).
   Web of Science ®Google Scholar
• Freudenberg U, Herman A, Welzel PB et al. A star-PEG-heaprin hydrogel platform to aid cell replacement therapies for neurodegeneration diseases. Biomaterials30(28), 5049–5060 (2009).
   PubMedGoogle Scholar
• Glowacki J, Mizuno S. Collagen scaffolds for tissue engineering. Biopolymers89(5), 338–344 (2007).
   Web of Science ®Google Scholar
• Sakai S, Hirose K, Taguchi K, Ogushi Y, Kawakami K. An injectable, in situ enzymatically gellable, gelatin derivative for drug delivery and tissue engineering. Biomaterials30(20), 3371–3377 (2009).
   PubMed Web of Science ®Google Scholar
• Kimelman-Bleich N, Pelled G, Sheyn D et al. The use of a synthetic oxygen carrier-enriched hydrogel to enhance mesenchymal stem cell-based bone formation in vivo. Biomaterials30(27), 4639–4648 (2009).
   PubMed Web of Science ®Google Scholar
• Wang Y, Kim HJ, Vunjak-Novakovic G, Kaplan DL. Stem cell-based tissue engineering with silk biomaterials. Biomaterials27(36), 6064–6082 (2006).
   PubMed Web of Science ®Google Scholar
• Daamen WF, Veerkamp JH, van Hest JCM, van Kuppevelt TH. Elastin as a biomaterial for tissue engineering. Biomaterials28(30), 4378–4398 (2007).
   PubMed Web of Science ®Google Scholar
• Mol A, van Lieshout MI, Dam-de Veen CG et al. Fibrin as a cell carrier in cardiovascular tissue engineering applications. Biomaterials26(16), 3113–3121 (2005).
   PubMed Web of Science ®Google Scholar
• Osathanon T, Linnes ML, Rajachar RM, Ratner BD, Somerman MJ, Giachelli CM. Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering. Biomaterials29(30), 4091–4099 (2008).
   PubMed Web of Science ®Google Scholar
• Yan H, Saiani A, Gough JE, Miller AF. Thermoreversible protein hydrogel as cell scaffold. Biomacromolecules7(10), 2776–2782 (2006).
   PubMed Web of Science ®Google Scholar
• Yan H, Frielinghaus H, Nykanen A, Ruokolainen J, SaianiA, Miller AF. Thermoreversible lysozyme hydrogels: properties and an insight into the gelation pathway. Soft Matter4(6), 1313–1325 (2008).
   PubMed Web of Science ®Google Scholar
• Kleinman HK, Martin GR. Matrigel: basement membrane matrix with biological activity. Semin. Cancer Biol.15(5), 378–386 (2005).
   PubMed Web of Science ®Google Scholar
• Morritt AN, Bortolotto SK, Dilley RJ et al. Cardiac tissue engineering in an in vivo vascularized chamber. Circulation115(3), 353–360 (2007).
   PubMed Web of Science ®Google Scholar
• Ponce ML. Tube formation: an in vitro matrigel angiogenesis assay. Methods Mol. Biol.467, 183–188 (2009).
   PubMedGoogle Scholar
• Ehrick JD, Deo SK, Browning TW, Bachas LG, Madou MJ, Daunert S. Genetically engineered protein in hydrogels tailors stimuli-responsive characteristic. Nat. Mater.4(4), 298–302 (2005).
   PubMed Web of Science ®Google Scholar
• Sengupta D, Heilshorn S. Protein-engineered biomaterials: Highly tunable tissue engineering scaffolds. Tissue Eng. Part B16(3), 285–293 (2010).
   Google Scholar
• Wong Po Foo CTS, Lee JS, Mulyasasmita W, Parisi-Amon A, Heilshorn SC. Two-component protein-engineered physical hydrogels for cell encapsulation. Proc. Natl Acad. Sci. USA105(52), 22067–22072 (2009).
   Google Scholar
• MacEwan SR, Chilkoti A. Elastin-like polypeptides: biomedical applications of tunable biopolymers. Pept. Sci.94(1), 60–77 (2010).
   Web of Science ®Google Scholar
• Romano NH, Sengupta D, Chung C, Heilshorn SC. Protein-engineering biomaterials: nanoscale mimcs of the extracellular matrix. Bioichim. Biophy. Acta1810(3), 339–349 (2011).
   PubMed Web of Science ®Google Scholar
• Dinerman AA, Cappello J, Ghandehari H, Hoag SW. Swelling behavior of a genetically engineered silk-elastin like protein polymer hydrogel. Biomaterials23(21), 4203–4210 (2002).
   PubMed Web of Science ®Google Scholar
• Greish K, Araki K, Li D et al. Silk-elastin like protein polymer hydrogels for localized adenoviral gene therapy of head and neck tumors. Biomacromolecules10(10), 2183–2188 (2009).
   PubMed Web of Science ®Google Scholar
• Davis NE, Ding S, Forster RE, Pinkas DM, Barron AE. Modular enzymatically crosslinked protein polymer hydrogels for in situ gelation. Biomaterials31(28), 7288–7297 (2010).
   Google Scholar
• Banta S, Wheeldon IR, Blenner M. Protein engineering in the development of functional hydrogels. Annu. Rev. Biomed. Eng.12, 167–186 (2010).
   PubMed Web of Science ®Google Scholar
• Kaufmann D, Fiedler A, Junger A, Auernheimer J, Kessler H, Weberskirch R. Chemical conjugation of linear and cyclic RGD moieties to a recombinant elastin-mimetic polypeptide – a versatile approach towards bioactive protein hydrogels. Macromol. Biosci.8(6), 577–588 (2008).
   Google Scholar
• Leach JB, Bivens KA, Patrick CW, Schmidt CE. Photocrosslinked hyaluronic acid hydrogels: Natural, biodegradable tissue engineering scaffolds. Biotechnol. Bioeng.82(5), 578–589 (2003).
   PubMed Web of Science ®Google Scholar
• Ramamurthi A, Vesely I. Ultraviolet light-induced modification of crosslinked hyaluronan gels. J. Biomed. Mater. Res. A66(2), 317–329 (2003).
   PubMedGoogle Scholar
• Denizli BK, Can HK, Rzaev ZMO, Guner A. Preparation conditions and swelling equilibria of dextran hydrogels prepared by some crosslinked agents. Polymer45(19), 6431–6435 (2004).
   Web of Science ®Google Scholar
• Kuo CK, Ma PX. Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: part I. Structure, gelation rate and mechanical properties. Biomaterials22(6), 511–521 (2001).
   PubMed Web of Science ®Google Scholar
• Kim IY, Seo SJ, Moon HS et al. Chitosan and its derivatives for tissue engineering applications. Biotechnol. Adv.26(1), 1–21 (2008).
   PubMed Web of Science ®Google Scholar
• Liang Y, Liu W, Han B et al. An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium. Coll. Surf. B82(1), 1–7 (2011).
   PubMed Web of Science ®Google Scholar
• Davidenko N, Campbell JJ, Thian ES, Watson CJ, Cameron RE. Collagen-hyaluronic acid scaffolds for adipose tissue engineering. Acta Biomater.6(10), 3957–3968 (2010).
   PubMed Web of Science ®Google Scholar
• Stabenfeldt SE, Garcia AJ, LaPlaca MC. Thermoreversible laminin-functionalized hydrogel for neural tissue engineering. J. Biomed. Mater. Res. A77(4), 718–725 (2006).
   PubMed Web of Science ®Google Scholar
• Shikanov A, Xu M, Woodruff TK, Shea LD. Interpenetrating fibrin-alginate matrices for in vitro ovarian follicle development. Biomaterials30(29), 5476–5485 (2009).
   Google Scholar
• Sakai S, Hashimoto I, Kawakami K. Synthesis of an agarose-gelatin conjugate for use as a tissue engineering scaffold. J. Biosci. Bioeng.103(10), 22–26 (2007).
   PubMed Web of Science ®Google Scholar
• Huang Y, Onyeri S, Siewe M, Moshfeghian A, Madihally SV. In vitro characterization of chitosan–gelatin scaffolds for tissue engineering. Biomaterials26(36), 7616–7627 (2005).
   PubMed Web of Science ®Google Scholar
• Dhandayuthapani B, Krishnan UM, Sethuraman S. Fabrication and characterization of chitosan-gelatin blend nanofiber for skin tissue engineering. J. Biomed. Mater. Res. B Appl. Biomater.94(1), 264–272 (2010).
   PubMed Web of Science ®Google Scholar
• Tan H, Wu J, Lao L, Gao C. Gelatin/chitosan/hyaluronan scaffold intergrated with PLGA microspheres for cartilage tissue engineering. Acta Biomater.5(1), 328–337 (2009).
   PubMed Web of Science ®Google Scholar
• Rosellini E, Cristallini C, Barbani N, Vozzi G, Giusti P. Preparation and characterization of alginate/gelatin blend films for cardiac tissue engineering. J. Biomed. Mater. Res. A91(2), 447–453 (2009).
   PubMed Web of Science ®Google Scholar
• Liu Y, Chan-Park MB. Hydrogel based on interpenetrating polymer networks of dextran and gelatin for vascular tissue engineering. Biomaterials30(2), 196–207 (2009).
   PubMed Web of Science ®Google Scholar
• Um SH, Lee JB, Park N, Kwon SY, Umbach CC, Luo D. Enzyme-catalysed assembly of DNA hydrogel. Nat. Mater.5(10), 797–801 (2006).
   PubMed Web of Science ®Google Scholar
• Xing Y, Cheng E, Yang Y et al. Self-assembled DNA hydrogels with designable thermal and enzymatic responsiveness. Adv. Mater.23(9), 1117–1121 (2011).
   PubMed Web of Science ®Google Scholar
• Lee CK, Shin SR, Lee SH et al. DNA hydrogel fiber with self-entanglement prepared by using an ionic liquid. Angew. Chem. Int. Ed.47(13), 2470–2474 (2008).
   Google Scholar
• Park N, Kahn J, Rice EJ et al. High-yield cell-free protein production from P-gel. Nat. Proto.4(12), 1759–1770 (2009).
   Google Scholar
• Park N, Um SH, Funabashi H, Xu J, Luo D. A cell-free protein-production gel. Nat. Mater.8(5), 432–437 (2009).
   PubMed Web of Science ®Google Scholar
• Schneider GB, English A, Abraham M, Zaharias R, Stanford C, Keller J. The effect of hydrogel charge density on cell attachment. Biomaterials25(15), 3023–3028 (2004).
   PubMed Web of Science ®Google Scholar
• Hejcl A, Sedy J, Kapcalova M et al. HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic spinal cord injury. Stem Cells Delvelop.19(10), 1535–1546 (2010).
   PubMed Web of Science ®Google Scholar
• Woerly S, Pinet E, de Robertis P, Van Diep D, Bousmina M. Spinal cord repair with PHPMA hydrogel containing RGD peptide (NeuroGel™). Biomaterials22(10), 1095–1111 (2001).
   PubMed Web of Science ®Google Scholar
• Takezawa T, Mori Y, Yoshizato K. Cell culture on a thermo-responsive polymer surface. Nat. Biotechnol.8(9), 854–856 (1990).
   Google Scholar
• Vihola H, Laukkanen A, Valtola L, Tenhu H, Hirvonen J. Cytotoxicity of thermosensitive polymers poly(N-isopropylacrylamide), poly(N-vinylcaprolactam) and amphiphilically modified poly(N-vinylcaprolactam). Biomaterials26(16), 3055–3064 (2005).
   PubMed Web of Science ®Google Scholar
• Park KH. Improved long-term culture of hepatocytes in a hydrogel containing Arg-Gly-Asp (RGD). Biotechnol. Lett.24(14), 1131–1135 (2002).
   Google Scholar
• Buxton AN, Zhu J, Marchant RE, West JL, Yoo JU, Johnstone B. Design and characterization of poly(ethylene glycol) photopolymerizable semi-interpenetrating networks for chondrogenesis of human mesenchymal stem cells. Tissue Eng.13(10), 2549–2560 (2007).
   PubMedGoogle Scholar
• Beamish JA, Zhu J, Kottke-Marchant K, Marchant RE. The effects of monoacrylate poly(ethylene glycol) on the properties of poly(ethylene glycol) diacrylate hydrogels used for tissue engineering. J. Biomed. Mater. Res. A92(2), 441–450 (2010).
   PubMedGoogle Scholar
• Yang F, Williams CG, Wang D, Lee H, Manson PN, Elisseeff J. The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. Biomaterials26(30), 5991–5998 (2005).
   PubMed Web of Science ®Google Scholar
• Higuchi A, Aoki N, Yamamoto T et al. Temperature-induced cell deattachment on immobilized pluronic surface. J. Biomed. Mater. Res. A79(2), 380–392 (2006).
   Google Scholar
• Schmedlen RH, Masters KS, West JL. Photocrosslinked polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. Biomaterials23(22), 4325–4332 (2002).
   PubMed Web of Science ®Google Scholar
• Ossipov DA, Brannvall K, Forsberg-Nilsson K, Hilborn J. Formation of the first injectable poly(vinyl alcohol) hydrogel by mixing of functional PVA precursors. J. Appl. Polym. Sci.106(1), 60–70 (2007).
   Web of Science ®Google Scholar
• Sawhney AS, Pathak CP, Hubbell JA. Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(α-hydroxy acid) diacrylate macromers. Macromolecules26(4), 581–587 (1993).
   Web of Science ®Google Scholar
• Jiang Z, Hao J, You Y, Liu Y, Wang Z, Deng X. Biodegradable and thermosensitive hydrogels of poly(ethylene glycol)-poly(ε-caprolactone-co-glycolide)-poly(ethylene glycol) aqueous solutions. J. Biomed. Mater. Res. A87(1), 45–51 (2008).
   PubMedGoogle Scholar
• Clapper JD, Skeie JM, Mullins RF, Guymon A. Development and characterization of photopolymerizable biodegradable materials from PEG–PLA–PEG block macromonomers. Polymer48(22), 6554–6564 (2007).
   Web of Science ®Google Scholar
• Sanabria-DeLong N, Agrawal SK, Bhatia SR, Tew GN. Impact of synthetic technique on PLA–PEO–PLA physical hydrogel properties. Macromolecules40(22), 7864–7873 (2007).
   Google Scholar
• Hudalla GA, Eng TS, Murphy WL. An approach to modulate degradation and mesenchymal stem cell behavior in poly(ethylene glycol) networks. Biomacromolecules9(3), 842–849 (2008).
   PubMed Web of Science ®Google Scholar
• Rydholm AE, Anseth KS, Bowman CN. Effects of neighboring sulfides and pH on ester hydrolysis in thiol-acrylate photopolymers. Acta Biomater.3(4), 449–455 (2007).
   PubMed Web of Science ®Google Scholar
• Zhang J, Skardal A, Prestwich GD. Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery. Biomaterials29(34), 4521–4531 (2008).
   PubMed Web of Science ®Google Scholar
• Deshmukh M, Singh Y, Gunaseelan S, Gao D, Stein S, Sinko PJ. Biodegradable poly(ethylene glycol) hydrogels based on a self-elimination degradation mechanism. Biomaterials.31(26), 6675–6684 (2010).
   Google Scholar
• Zustiak SP, Leach JB. Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties. Biomacromolecules11(5), 1348–1357 (2010).
   PubMed Web of Science ®Google Scholar
• Li Q, Wang J, Shahani S et al. Biodegradable and photocrosslinkable poly(phophoester hydrogel. Biomaterials27(7), 1027–1034 (2006).
   PubMed Web of Science ®Google Scholar
• Haihara S, Matsumura S, Fisher JP. Synthesis and characterization of cyclic acetal based degradable hydrogels. Eur. J. Pharm. Biopharm.68(1), 67–73 (2008).
   Google Scholar
• Malkoch M, Vestberg R, Gupta N et al. Synthesis of well-defined hydrogel networks using Click chemistry. Chem. Commun.26, 2774–2776 (2006).
   PubMedGoogle Scholar
• Jo S, Engel PS, Mikos AG. Synthesis of poly(ethylene glycol)-tethered poly(propylene fumarate) and its modification with GRGD peptide. Polymer41(21), 7595–7604 (2000).
   Web of Science ®Google Scholar
• He X, Ma J, Jabbari E. Effect of grafting RGD and BMP-2 protein-derived peptides to a hydrogel substrate on osteogenic diffierentiation of marrow stromal cells. Langmuir24(21), 12508–12516 (2008).
   PubMed Web of Science ®Google Scholar
• Atzet S, Curtin S, Trinh P, Bryant S, Ratner B. Degradation poly(2-hydroxyl methacrylate)-co-polycaprolactone hydrogels for tissue engineering scaffolds. Biomacromolecules9(12), 3370–3377 (2008).
   PubMed Web of Science ®Google Scholar
• Hauser CAE, Zhang S. Designer self-assembling peptides nanofiber biological materials. Chem. Soc. Rev.39, 2780–2790 (2010).
   PubMed Web of Science ®Google Scholar
• Zhao X, Zhang S. Designer self-assembling peptide materials. Macromol. Biosci.7(1), 13–22 (2007).
   PubMed Web of Science ®Google Scholar
• Stupp SI. Self-assembly and biomaterials. Nano Lett.10(12), 4783–4786 (2010).
   Web of Science ®Google Scholar
• Capito RM, Azevedo HS, Velichko YS, Mata A, Stupp SI. Self-assembly of large and small molecules into hierarchically ordered sacs and membranes. Science319(5871), 1812–1816 (2008).
   PubMed Web of Science ®Google Scholar
• Ulijin RV, Smith AM. Designing peptide based nanomaterials. Chem. Soc. Rev.37, 664–675 (2008).
   PubMed Web of Science ®Google Scholar
• Jayawarna V, Richardson SM, Hirst AR et al. Introducing chemical functionality into Fmoc-peptide gels for cell culture. Acta Biomater.5(3), 934–943 (2009).
   Google Scholar
• Galler KM, Aulisa L, Regan KR, D’Souza RN, Hartgerink JD. Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading. J. Am. Chem. Soc.132(9), 3217–3223 (2010).
   Google Scholar
• Kopesky PW, Vanderploeg EJ, Sandy JS, Kurz B, Grodzinsky AJ. Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells. Tissue Eng. A16(2), 465–477 (2010).
   PubMedGoogle Scholar
• Anderson JM, Andukuri A, Lim DJ, Jun HW. Modulating the gelation properties of self-assembling peptide amphiphiles. ACS Nano3(10), 3447–3454 (2009).
   Google Scholar
• Liu J, Song H, Zhang L, Xu H, Zhao X. Self-assembly-peptide hydrogels as tissue engineering scaffolds for three-dimensional culture of chondrocytes in vitro. Macromol. Biosci.10(10), 1164–1170 (2010).
   PubMed Web of Science ®Google Scholar
• Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J. Biomed. Mater. Res.39(2), 266–276 (1998).
   PubMed Web of Science ®Google Scholar
• Shin H, Jo S, Mikos AG. Biomimetic materials for tissue engineering. Biomaterials24(24), 4353–4364 (2003).
   PubMed Web of Science ®Google Scholar
• Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol.23(1), 47–55 (2005).
   PubMed Web of Science ®Google Scholar
• Silva AKA, Richard C, Bessodes M, Scherman D, Merten OW. Growth factor delivery approaches in hydrogels. Biomacromolecules10(1), 9–18 (2009).
   PubMed Web of Science ®Google Scholar
• Zisch AH, Lutolf MP, Hubbell JA. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovasc. Pathol.12(6), 295–310 (2003).
   PubMed Web of Science ®Google Scholar
• Lee HJ, Lee JS, Chansakul T, Yu C, Elisseef JH, Yu SM. Collagen mimetic peptide-conjugated photopolymerizable PEG hydrogel. Biomaterials27(30), 5268–5276 (2006).
   PubMed Web of Science ®Google Scholar
• Jing P, Rudra JS, Herr AB, Collier JH. Self-assembling peptide-polymer hydrogels designed from the coiled coil region of fibrin. Biomacromolecules9(9), 2438–2446 (2008).
   PubMed Web of Science ®Google Scholar
• Salinas CN, Anseth KS. Decorin moieties tethered into PEG networks induce chondrogenesis of human mesenchymal stem cells. J. Biomed. Mater. Res. A90(2), 456–464 (2009).
   PubMedGoogle Scholar
• Cheung CY, McCartney SJ, Anseth KS. Synthesis of polymerizable superoxide dismutase mimetics to reduce reactive oxygen species damage in transplanted biomedical devices. Adv. Funct. Mater.18(20), 3119–3126 (2008).
   Google Scholar
• Cheung CY, Anseth KS. Synthesis of immunoisolation barriers that provide localized immunosuppression for encapsulated pancreatic islets. Bioconjug. Chem.17(4), 1036–1042 (2006).
   PubMed Web of Science ®Google Scholar
• Lin CC, Metters AT, Anseth KS. Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFα. Biomaterials30(28), 4907–4914 (2009).
   PubMed Web of Science ®Google Scholar
• Su J, Hu BH, Lowe WL, Kaufman DB, Messersmith PB. Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation. Biomaterials31(2), 308–314 (2010).
   PubMed Web of Science ®Google Scholar
• Lipke EA, West JL. Localized delivery of nitric oxide from hydrogels inhibits neointima formation in a rat carotid balloon injury model. Acta Biomater.1(6), 597–606 (2005).
   PubMed Web of Science ®Google Scholar
• Jia X, Kiick KL. Hybrid multicomponent hydrogels for tissue engineering. Macromol. Biosci.9(2), 140–156 (2009).
   PubMed Web of Science ®Google Scholar
• Hiemstra C, van der Aa LJ, Zhong Z, Kijkstra PJ, Feijen Jan. Rapidly in situ-forming degradable hydrogels form dextran thiols through Michael addition. Biomacromolecules8(5), 1548–1556 (2007).
   PubMed Web of Science ®Google Scholar
• Zieris A, Prokoph S, Levental KR et al. FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis. Biomaterials31(31), 7985–7994 (2010).
   PubMed Web of Science ®Google Scholar
• Jin R, Teixeira LSM, Krouwels A et al. Synthesis and characterization of hyaluronic acid-poly(ethylene glycol) hydrogels via Michael addition: an injectable biomaterial for cartilage repair. Acta Biomater.6(6), 1968–1977 (2010).
   PubMed Web of Science ®Google Scholar
• Strehin I, Nahas Z, Arora K, Nguyen T, Elisseeff J. A versatile pH sensitive chondroitin sulphate–PEG tissue adhesive and hydrogel. Biomaterials31(10), 2788–2797 (2010).
   PubMed Web of Science ®Google Scholar
• Rizzi SC, Hubbell JA. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part I: development and physiochemical characteristics. Biomacromolecules6(3), 1226–1238 (2005).
   PubMed Web of Science ®Google Scholar
• Appelman TP, Mizrahi J, Elisseeff JH, Seliktar D. The influence of biological motifs and dynamic mechanical stiulation in hydrogel scaffold systems on the phenotype of chondrocytes. Biomaterials32(6), 1508–1516 (2011).
   Google Scholar
• Li F, Griffith M, Li Z et al. Recruitment of multiple cell lines by collagen-synthetic copolymer matrices in corneal regeneration. Biomaterials26(16), 3093–3104 (2005).
   PubMed Web of Science ®Google Scholar
• Wang C, Stewart RJ, Kopecek J. Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains. Nature397(6718), 417–420 (1999).
   PubMed Web of Science ®Google Scholar
• Chen JP, Cheng TH. Thermo-responsive chitosan-graft-poly(N-isopropylacrylamide) injectable hydrogel for cultivation of chondrocytes and meniscus cells. Macromol. Biosci.6(12), 1026–1039 (2006).
   PubMed Web of Science ®Google Scholar
• Tan H, Ramirez CM, Miljkovic N, Li H, Rubin JP, Marra KG. Thermosensitive injectable hyaluronic acid hydrogel for adipose tissue engineering. Biomaterials30(36), 6844–6853 (2009).
   PubMed Web of Science ®Google Scholar
• Prabaharan M, Mano JF. Stimuli-responsive hydrogels based on polysaccharides incorporated with thermo-resoponsive polymers as novel biomaterials. Macromol. Biosci.6(12), 991–1008 (2006).
   PubMed Web of Science ®Google Scholar
• Myles JL, Burgess BT, Dickinson RB. Modification of the adhesive properties of collagen by covalent grafting with RGD peptides. J. Biomater. Sci. Polym. Ed.11(1), 69–86 (2000).
   PubMed Web of Science ®Google Scholar
• Shachar M, Tsur-Gang O, Dvir T, Leor J, Cohen S. The effect of immobilized RGD peptide in alginate scaffolds on cardiac tissue engineering. Acta Biomater.7(1), 152–162 (2011).
   PubMed Web of Science ®Google Scholar
• Connelly JT, Garcia AJ, Levenston ME. Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. Biomaterials28(6), 1071–1083 (2007).
   PubMed Web of Science ®Google Scholar
• Khetan S, Katz JS, Burdick JA. Sequential crosslinking to control cellular spreading in 3-dimensional hydrogels. Soft Matter5(8), 1601–1606 (2009).
   Google Scholar
• Shu XZ, Ghosh K, Liu Y, Palumbo FS, Clark RA, Prestwich GD. Attachment and spreading of fibroblasts on an RGD peptide-modified hyaluronan hydrogel. J. Biomed. Mater. Res. A68(2), 365–375 (2004).
   PubMed Web of Science ®Google Scholar
• Kimura T, Nam K, Mutsuo S et al. Preparation of poly(vinyl alcohol)/DNA hydrogels via hydrogen bonds formed on ultra-high pressurization and controlled release of DNA from the hydrogels for gene delivery. J. Artif. Organs10(2), 104–108 (2007).
   Google Scholar
• Bryant SJ, Davis-Arehart KA, Luo N, Shoemaker RK, Arthur JA, Anseth KS. Synthesis and characterization of photopolymerized multifunctional hydrogels: water-soluble poly(vinyl alcohol) and chondroitin sulfate macromers for chondrocyte encapsulation. Macromolecules37(18), 6726–6733 (2004).
   Web of Science ®Google Scholar
• Lin C, Zhao P, Li F, Guo F, Li Z, Wen X. Thermosensitive in situ-forming dextran-pluronic hydrogels through Michael addition. Mater. Sci. Eng. C30(8), 1236–1244 (2010).
   Web of Science ®Google Scholar
• Wang C, Kopecek J, Stewart RJ. Hybrid hydrogels cross-linked by genetically engineered coiled-coil block proteins. Biomacromolecules2(3), 912–920 (2001).
   Google Scholar
• Scott JE. Extracellular matrix, supramolecular organization and shape. J. Anat.187, 259–269 (1995).
   PubMed Web of Science ®Google Scholar
• Rhodes JM, Simons M. The extracellular matrix and blood vessel formation; not just a scaffold. J. Cell. Mol. Med.11(2), 176–205 (2007).
   PubMed Web of Science ®Google Scholar
• Ma PX. Biomimetic materials for tissue engineering. Adv. Drug Deliver. Rev.60(2), 184–198 (2008).
   PubMed Web of Science ®Google Scholar
• Chen R, Hunt JA. Biomimetic materials processing for tissue-engineering processes. J. Mater. Chem.17(38), 3974–3979 (2007).
   Web of Science ®Google Scholar
• Tibbitt MW, Anseth KS. Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol. Bioeng.103(4), 655–663 (2009).
   PubMed Web of Science ®Google Scholar
• Zhu J, Beamish JA, Tang C, Kottke-Marchant K, Marchant RE. Extracellular matrix-like cell-adhesive hydrogels form RGD-containing poly(ethylene glycol) diacrylate. Macromolecules39(4), 1305–1307 (2006).
   Web of Science ®Google Scholar
• Zhu J, Tang C, Kottke-Marchant K, Marchant RE. Design and synthesis of biomimetic hydrogel scaffolds with controlled organization of cyclic RGD peptides. Bioconjug. Chem.20(2), 333–339 (2009).
   Google Scholar
• Zhu J, Marchant RE. Solid-phase synthesis of tailed cyclic RGD peptides using glutamic acid: unexpected glutarimide formation. J. Pept. Sci.14, 690–696 (2008).
   Google Scholar
• Liu SQ, Ee PLR, Ke CY, Hedrick JL, Yang YY. Biodegradable poly(ethylene glycol)-peptide hydrogels with well-defined structure and properties for cell delivery. Biomaterials30(8), 1453–1461 (2009).
   PubMed Web of Science ®Google Scholar
• Polizzotti BD, Fairbanks BD, Anseth KS. Three-dimensional biochemical patterning of Click-based composite hydrogels via thiolene photopolymerization. Biomacromolecules9(4), 1084–1087 (2008).
   PubMed Web of Science ®Google Scholar
• Liu SQ, Tian Q, Wang L et al. Injectable biodegradable poly(ethylene glycol)/RGD peptide hybrid hydrogels for in vitro chondrogenesis of human mesenchymal stem cells. Macromol. Rapid Commun.31(13), 1148–1154 (2010).
   Google Scholar
• Zhou M, Smith AM, Das AK et al. Self-assembled peptide-based hydrogels as scaffolds for anchorage-dependent cells. Biomaterials30(13), 2523–2530 (2009).
   PubMed Web of Science ®Google Scholar
• Comisar WA, Hsiong SX, Kong HJ, Mooney MJ, Linderman JJ. Multi-scale modeling to predict ligand presentation within RGD nanopatterned hydrogels. Biomaterials27(10), 2322–2329 (2006).
   PubMed Web of Science ®Google Scholar
• Studenovska H, Vodicka P, Proks V, Hlucilova J, Motlik J, Rypacek F. Synthetic poly(amino acid) hydrogels with incorporated cell-adhesive peptide for tissue engineering. J. Tissue Eng. Regen. Med.4(6), 454–463 (2010).
   Google Scholar
• Herten M, Jung TE, Rothamel D et al. Biodegradation of different synthetic hydrogels made of polyethylene glycol hydrogel/RGD-peptide modificaitons: an immunohistochemical study in rats. Clin. Oral. Impl. Res.20(2), 116–125 (2009).
   Google Scholar
• Schmidt DR, Kao WJ. Monocyte activation in response to polyethylene glycol hydrogels grafted with RGD and PHSRN separated by interpositional spacers of various length. J. Biomed. Mater. Res. A83(3), 617–625 (2007).
   PubMed Web of Science ®Google Scholar
• Benoit DSW, Anseth KS. The effect on osteoblast function of coloclized RGD and PHSRN epitopes on PEG surfaces. Biomaterials26(25), 5209–5220 (2005).
   PubMed Web of Science ®Google Scholar
• Masters KS, Shah DN, Walker G, Leinwand LA, Anseth KS. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J. Biomed. Mater. Res. A71(1), 172–180 (2004).
   PubMedGoogle Scholar
• Peyton SR, Raub CB, Keschrumrus VP, Putnam AJ. The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells. Biomaterials27(28), 4881–4893 (2006).
   PubMed Web of Science ®Google Scholar
• Park CH, Hong YJ, Park K, Han DK. Peptide-grafted lactide-based poly(ethylene glycol) porous scaffolds for specific cell adhesion. Macromol. Res.18(5), 526–532 (2010).
   Google Scholar
• Massia SP, Hubbell JA. Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin α4 β1. J. Biol. Chem.267(20), 14019–14036 (1992).
   PubMed Web of Science ®Google Scholar
• Drake SL, Varnum J, Mayo KH, Letourneau PC, Furcht LT, McCarthy JB. Structure features of fibronectin synthetic peptide FN-C/H II, responsive for cell adhesion, neurite extension, and heparin. J. Biol. Chem.268(21), 15859–15867 (1993).
   Google Scholar
• Hansen LK, O’Leary JJ, Skubitz APN, Furcht LT, McCarthy JB. Identification of a homologous heparin binding peptide sequence present in fibronectin and the 70 kDa family of heat-shock proteins. Biochim. Biophys. Acta1252(1), 135–145 (1995).
   Google Scholar
• Woods A, McCarthy JB, Furcht LT, Couchman JR. A synthetic peptide from the COOH-terminal heparin-binding domain of fibronectin promotes focal adhesion formation. Mol. Biol. Cell4(6), 605–613 (1993).
   PubMed Web of Science ®Google Scholar
• Klim JR, Li L, Wrighton PJ, Piekarczyk MS, Kiessling LL. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat. Methods7(12), 989–994 (2010).
   PubMed Web of Science ®Google Scholar
• Nomizu M, Weeks BS, Weston CA, Kim WH, Kleinman HK, Yamada Y. Structure–activity study of a laminin α1 chain active peptide segment Ile–Lys–Val–Ala–Val (IKVAV). FEBS Lett.365(2–3), 227–231 (1995).
   Google Scholar
• Hynd MR, Frampton JP, Dowell-Mesfin N, Turner JN, Shain W. Directed cell growth on protein-functionalized hydrogel surfaces. J. Neurosci. Meth.162(1–2), 255–263 (2007).
   PubMedGoogle Scholar
• Saha K, Irwin EF, Kozhukh J, Schaffer DV, Healy KE. Biomimetic interfacial interpenetrating polymer networks control neural stem cell behavior. J. Biomed. Mater. Res. A81(1), 240–249 (2007).
   PubMed Web of Science ®Google Scholar
• Santiago LY, Nowak RW, Rubin JP, Marra KG. Peptide-surface modification of poly(caprolactone) with laminin-derived sequences for adipose-derived stem cell applications. Biomaterials27(15), 2962–2969 (2006).
   PubMed Web of Science ®Google Scholar
• Zustiak SP, Durbal R, Leach JB. Influence of cell-adhesive peptide ligands on poly(ethylene glycol) hydrogel physical, mechanical and transport properties. Acta Biomater.6(9), 3404–3414 (2010).
   Google Scholar
• Tsur-Gang O, Ruvinov E, Landa N et al. The effects of peptide-based modification of alginate on left ventricular remodeling and function after myocardial infarction. Biomaterials30(2), 189–195 (2009).
   PubMed Web of Science ®Google Scholar
• Xu J, Zhou X, Ge H et al. Endothelial cells anchoring by functionalized yeast polypeptide. J. Biomed. Mater. Res. A87(3), 819–821 (2008).
   Google Scholar
• Fittkau MH, Zilla P, Bezuidenhout D et al. The selective modulating of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides. Biomaterials26(2), 167–174 (2005).
   PubMed Web of Science ®Google Scholar
• Webber LM, Anseth KS. Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion. Matrix Biol.27(8), 667–673 (2008).
   Google Scholar
• Webber LM, Haydam KN, Haskins K, Anseth KS. The effects of cell-matrix interactions on encapsulated β-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials28(19), 3004–3011 (2007).
   Google Scholar
• Luzak B, Golanski J, Rozalski M, Boncler MA, Watala C. Inhibition of collagen-induced platelet reactivity by DGEA peptide. Acta Biochim. Pol.50(4), 1119–1128 (2003).
   PubMed Web of Science ®Google Scholar
• Mineur P, Guignandon A, Lambert CA, Lapiere CM, Nusgens BV. RGDS and DGEA-induced [Ca2+]i signaling in human dermal fibroblast. Biochim. Biophys. Acta1746(1), 28–37 (2005).
   Google Scholar
• Renner C, Sacca B, Moroder L. Synthetic heterotrimeric collagen peptides as mimics of cell adhesion sites of the basement membrane. Biopolymers76(1), 34–47 (2004).
   PubMed Web of Science ®Google Scholar
• Mann BK, West JL. Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds. J. Biomed. Mater. Res.60(1), 86–93 (2002).
   PubMed Web of Science ®Google Scholar
• Mann BK, Schmedlen RH, West JL. Tethered-TGF-β increases extracellular matrix production of vascular smooth muscle cells. Biomaterials22(5), 439–444 (2001).
   PubMed Web of Science ®Google Scholar
• Mann BK, Tsa AT, Scott-Burden T, West JL. Modification of surfaces with cell adhesion peptides alters extracellular matrix deposition. Biomaterials20(23–24), 2281–2286 (1999).
   PubMed Web of Science ®Google Scholar
• Nagase H, Fields GB. Human matrix metalloproteinase specificity studies using collagen sequence-based synthetic peptides. Biopolymers40(4), 399–416 (1996).
   PubMed Web of Science ®Google Scholar
• Turk BE, Huang LL, Piro ET, Cantley LC. Determination of protease cleavage site motifs using mixture-based oriented peptide libraries. Nat. Biotechnol.19(7), 661–667 (2001).
   PubMed Web of Science ®Google Scholar
• Miller JS, Shen CJ, Legant WR, Baranski JD, Blakely BL, Chen CS. Bioactive hydrogels made from step-growth derived PEG-peptide macromers. Biomaterials31(13), 3736–3743 (2010).
   Google Scholar
• Tsubota Y, Mizushima H, Hirosaki T, Higashi S, Yasumitsu H, Miyazaki K. Isolation and activity of proteolytic fragment of laminin-5 α3 chain. Biochem. Biophys. Res. Commun.278(3), 614–620 (2000).
   PubMedGoogle Scholar
• Ogawa T, Tsubota Y, Maeda M, Kariya Y, Miyazaki K. Regulation of biological activity of laminin-5 by proteolytic processing of γ2 chain. J. Cell. Biochem.92(4), 701–714 (2004).
   Google Scholar
• Pirila E, Sharabi A, Salo T et al. Matrix metalloproteinases process the laminin-5 γ2 chain and regulate epithelial cell migration. Biochem. Biophys. Res. Commun.303(4), 1012–1017 (2003).
   PubMed Web of Science ®Google Scholar
• Shikanov A, Smith RM, Xu M, Woodruff TK, Shea LD. Hydrogel network design using multifunctional macromers to coordinate tissue maturation in ovarian follicle culture. Biomaterials32(10), 2524–2531 (2011).
   PubMed Web of Science ®Google Scholar
• Jo YS, Rizzi SC, Ehrbar M, Weber FZ, Hubbell JA, Lutolf MP. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. J. Biomed. Mater. Res. A93(3), 870–877 (2010).
   Google Scholar
• Halstenberg S, Panitch A, Rizzi S, Hall H, Hubbell JA. Biologically engineered protein-graft-poly(ethylene glycol) hydrogels: a cell adhesive and plasmin-degradable biosynthetic material for tissue repair. Biomacromolecules3(4), 710–723 (2002).
   PubMed Web of Science ®Google Scholar
• Fosang AJ, Last K, Knauper V, Murphy G, Neame PJ. Degradation of cartilage aggrecan by collagenase-3 (MMP-13). FEBS Lett.380(1–2), 17–20 (1996).
   PubMed Web of Science ®Google Scholar
• Salinas CN, Anseth KS. The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials29(15), 2370–2377 (2008).
   PubMed Web of Science ®Google Scholar
• Bott K, Upton Z, Schrobback K et al. The effect of matrix characteristics on fibroblast proliferation. Biomaterials31(32), 8454–8464 (2010).
   PubMed Web of Science ®Google Scholar
• Lutolf MP, Weber FE, Schmoekel HG et al. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nat. Biotechnol.21(5), 513–518 (2003).
   PubMed Web of Science ®Google Scholar
• Raeber GP, Lutolf MP, Hubbell JA. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs. Acta Biomater.3(5), 615–629 (2007).
   Google Scholar
• Phelps EA, Landazuri N, Thule PM, Taylor WB, Garcia AJ. Bioartificial matrices for therapeutic vascularization. Proc. Natl Acad. Sci. USA107(8), 3323–3328 (2010).
   PubMed Web of Science ®Google Scholar
• DeForest CA, Polizzotti BD, Anseth KS. Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat. Mater.8(8), 659–664 (2009).
   PubMed Web of Science ®Google Scholar
• He X, Jabbari E. Material properties and cytocompatibility of injectable MMP degradable poly(lactide ethylene oxide fumarate) hydrogel as a carrier for marrow stromal cells. Biomacromolecules8(3), 780–792 (2007).
   PubMed Web of Science ®Google Scholar
• Lee SH, Moon JJ, Miller JS, West JL. Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualized collagenase activity during three-dimensional cell migration. Biomaterials28(20), 3163–3170 (2007).
   PubMed Web of Science ®Google Scholar
• Keen I, Lambert L, Chirila TV, Paterson SM, Whittaker AK. Degradable hydrogels for tissue engineering – part I: synthesis by RAFT polymerization and characterization of PHEMA containing enzymatically degradable crosslinks. J. Biomim. Biomater. Tissue Eng.6, 67–85 (2010).
   Google Scholar
• Patel PN, Gobin AS, West JL, Patrick CW. Poly(ethylene glycol) hydrogel system supports preadipocyte viability, adhesion, and proliferation. Tissue Eng.11(9–10), 1498–1505 (2005).
   PubMedGoogle Scholar
• West JL, Hubbell JA. Polymeric biomaterials with degradation sites for proteases involved in cell migration. Macromolecules32(1), 241–244 (1999).
   Web of Science ®Google Scholar
• Mann BK, Gobin AS, Tsai AT, Schmedlen RH, West JL. Smooth muscle cell growth in photopolymerized hydrogels with cell adhesion and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. Biomaterials22(22), 3045–3051 (2001).
   PubMed Web of Science ®Google Scholar
• Patrick AG, Ulijin RV. Hydrogels for the detection and management of protease levels. Macromol. Biosci.10(10), 1184–1193 (2010).
   Google Scholar
• Pak CC, Erukulla RK, Ahl PL, Janoff AD, Meers P. Elastase activated liposomal delivery to nucleated cells. Biochim. Biophys. Acta1419(2), 111–126 (1999).
   PubMed Web of Science ®Google Scholar
• Aimetti AA, Tibbitt MW, Anseth KS. Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels. Biomacromolecules10(6), 1484–1489 (2009).
   PubMed Web of Science ®Google Scholar
• Casadio YS, Brown DH, Chirila TV, Kraatz HB, Baker MV. Biodegradable poly(2-hydroxyethyl methacrylate) (PHEMA) and poly{(2-hydroxyl methacrylate)-co-[poly(ethylene glycol) methyl ether methacrylate]} hydrogels containing peptide-based cross-linking agents. Biomacromolecules11(11), 2949–2959 (2010).
   PubMed Web of Science ®Google Scholar
• Fairbanks BD, Schwartz MP, Halevi AE, Nuttelman CR, Bowman CN, Anseth KS. A versatile synthetic extracellular matrix mimic via thioi-norbornene photopolymerization. Adv. Mater.21(48), 5005–5010 (2009).
   PubMed Web of Science ®Google Scholar
• Ahrendt G, Chickering DE, Ranieri JP. Angiogenic growth factor: A review for tissue engineering. Tissue Eng.4(2), 117–130 (1998).
   Google Scholar
• Chen RR, Mooney DJ. Polymeric growth factor delivery strategies for tissue engineering. Pharm. Res.20(80), 1103–1112 (2003).
   PubMed Web of Science ®Google Scholar
• Phelps EA, Garcia AJ. Update on therapeutic vascularization strategies. Regen. Med.4(1), 65–80 (2009).
   PubMed Web of Science ®Google Scholar
• Zhang S, Uludag H. Nanoparticle systems for growth factor delivery. Pharm. Res.26(7), 1561–1579 (2009).
   PubMed Web of Science ®Google Scholar
• Taipale J, Keski-Oja J. Growth factors in the extracellular matrix. FASEB J.11(1), 51–59 (1997).
   PubMed Web of Science ®Google Scholar
• Whitelock JM, Murdoch AD, Iozzo RV, Underwoods PA. The degradation of human endothelial cell-derived perlecan and release bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases. J. Biol. Chem.271(17), 10079–10086 (1996).
   PubMed Web of Science ®Google Scholar
• Hiemstra C, Zhong Z, van Steenbergen MJ, Hennink WE, Feijen J. Release of model proteins and basic fibroblast growth factor from in situ forming degradable dextran hydrogels. J. Control. Release122(1), 71–78 (2007).
   PubMed Web of Science ®Google Scholar
• Andreopoulos FM, Persaud I. Delivery of basic fibroblast growth factor (bFGF) from photoresponsive hydrogel scaffolds. Biomaterials27(11), 2468–2476 (2006).
   PubMed Web of Science ®Google Scholar
• Burdick JA, Mason MN, Hinman AD, Thorne K, Anseth KS. Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. J. Control. Release83(1), 53–63 (2002).
   PubMed Web of Science ®Google Scholar
• van de Wetering P, Metters AT, Schoenmakers RG, Hubbell JA. Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins. J. Control. Release102(3), 619–627 (2005).
   PubMed Web of Science ®Google Scholar
• Lim SM, Oh SH, Lee HH, Yuk SH, Im GI, Lee JH. Dual growth factor-releasing nanoparticle/hydrogel system for cartilage tissue engineering. J. Mater. Sci. Mater. Med.21(9), 2593–2600 (2010).
   PubMed Web of Science ®Google Scholar
• Ferreira LS, Gerecht S, Fuller J, Shieh HF, Vunjak-Novakovic G, Langer R. Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells. Biomaterials28(17), 2706–2717 (2007).
   PubMed Web of Science ®Google Scholar
• Moya ML, Cheng MH, Huang JJ et al. The effect of FGF-1 loaded alginate microbeads on neovascularization and adipogenesis in a vascular pedicle model of adipose tissue engineering. Biomaterials31(10), 2816–2826 (2010).
   PubMed Web of Science ®Google Scholar
• Chen RR, Silve EA, Yuen WW et al. Integrated approach to designing growth factor delivery systems. FASEB J.21(14), 3896–3903 (2007).
   PubMed Web of Science ®Google Scholar
• Park H, Temenoff J, Tabata Y, Caplan AI, Mikos AG. Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials28(21), 3217–3227 (2007).
   PubMed Web of Science ®Google Scholar
• Jay SM, Stepherd BR, Bertram JP, Pober JS, Saltzman WM. Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation. FASEB J.22(8), 2919–2956 (2008).
   Google Scholar
• Jay SM, Saltzman WM. Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. J. Control. Release134(1), 26–34 (2009).
   PubMed Web of Science ®Google Scholar
• Ho YC, Wu SJ, Mi FL et al. Thiol-modified chitosan sulfate nanoparticles for protection and release of basic fibroblast growth factor. Bioconjug. Chem.21(1), 28–38 (2010).
   Google Scholar
• Ehrbar M, Rizzi SC, Hlushchuk R et al. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering. Biomaterials28(26), 3856–3866 (2007).
   PubMed Web of Science ®Google Scholar
• Zisch AH, Schenk U, Schense JC, Sakiyama-Elbert SE, Hubbell JA. Covalently conjugated VEGF–fibrin matrices for endothelialization. J. Control. Release72(1–3), 101–103 (2001).
   PubMed Web of Science ®Google Scholar
• Seliktar D, Zisch AH, Lutolf MP, Wrana JL, Hubbell JA. MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing. J. Biomed. Mater. Res. A68(4), 704–716 (2004).
   PubMed Web of Science ®Google Scholar
• Gobin AS, West JL. Effects of epidermal growth factor on fibroblast migration through biomimetic hydrogels. Biotechnol. Prog.19(6), 1781–1785 (2003).
   PubMed Web of Science ®Google Scholar
• Mann BK, Schmedlen RH, West JL. Tethered-TGF-β increases extracellular matrix production of vascular smooth muscle cells. Biomaterials22(5), 439–444 (2001).
   PubMed Web of Science ®Google Scholar
• DeLong SA, Moon JJ, West JL. Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration. Biomaterials26(16), 3227–3234 (2005).
   PubMed Web of Science ®Google Scholar
• He X, Ma J, Jabbari E. Effect of grafting RGD and BMP-2 protein-derived peptides to a hydrogel substrate on osteogenic diffierentiation of marrow stromal cells. Langmuir24(21), 12508–12516 (2008).
   PubMed Web of Science ®Google Scholar
• Benoit DSW, Durney AR, Anseth KS. The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation. Biomaterials28(1), 66–77 (2007).
   PubMed Web of Science ®Google Scholar
• Tae G, Kim YJ, Choi WI, Kim M, Stayton PS, Hoffman AS. Formation of a novel heparin-based hydroel in the presence of heparin-binding biomolecules. Biomacromolecules8(6), 1979–1986 (2007).
   PubMed Web of Science ®Google Scholar
• Zhang L, Furst EC, Kiick KL. Manipulation of hydrogel assembly and growth factor delivery via the use of peptide-polysaccharide interactions. J. Control. Release114(2), 130–142 (2006).
   PubMed Web of Science ®Google Scholar
• Nie T, Akins RE, Kiick KL. Production of heparin-containing hydrogels for modulating cell responses. Acta Biomater.5(3), 865–875 (2009).
   PubMed Web of Science ®Google Scholar
• Yamaguchi N, Zhang L, Chae BS, Palla CS, Furst EM, Kiick KL. Growth factor mediated assembly of cell receptor-responsive hydrogels. J. Am. Chem. Soc.129(11), 3040–3041 (2007).
   PubMed Web of Science ®Google Scholar
• Nakamura S, Ishihara M, Obara K et al. Controlled release of fibroblast growth factor-2 from an injectable 6-O-desulfated heparin hydrogel and subsequent effect on in vivo vascularization. J. Biomed. Mater. Res. A78(2), 364–371 (2006).
   Google Scholar
• Fujita M, Ishihara M, Simizu M et al. Vascularization in vivo caused by the controlled release of fibroblast growth factor-2 from an injectable chitosan/non-anticoagulant heparin hydrogels. Biomaterials25(4), 699–706 (2004).
   PubMed Web of Science ®Google Scholar
• Cai S, Liu Y, Zheng X, Prestwich GD. Injectable glycosaminoglyosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials26(30), 6054–6067 (2005).
   PubMed Web of Science ®Google Scholar
• Rajangam K, Arnold MS, Rocco MA, Stupp SI. Peptide amphiphile nanostructure-heparin interactions and their relationship to bioactivity. Biomaterials29(23), 3298–3305 (2008).
   PubMed Web of Science ®Google Scholar
• Lin CC, Anseth KS. Controlling affinity binding with peptide-functionalized poly(ethylene glycol) hydrogels. Adv. Funct. Mater.19(14), 2325–2331 (2009).
   Google Scholar