Functionalized carbon nanotubes for anticancer drug delivery

References

• Farokhzad OC, Langer R. Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv. Drug Deliver. Rev.58(14), 1456–1459 (2006).
   PubMed Web of Science ®Google Scholar
• Davis ME, Chen Z, Shin DM. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov.7(9), 771–782 (2008).
   PubMed Web of Science ®Google Scholar
• Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol.2(12), 751–760 (2007).
   PubMed Web of Science ®Google Scholar
• Pastorin G. Crucial functionalizations of carbon nanotubes for improved drug delivery: a valuable option? Pharm. Res.26(4), 746–769 (2009).
   PubMed Web of Science ®Google Scholar
• Lacerda L, Bianco A, Prato M, Kostarelos K. Carbon nanotubes as nanomedicines: from toxicology to pharmacology. Adv. Drug Deliver. Rev.58(14), 1460–1470 (2006).
   PubMed Web of Science ®Google Scholar
• Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr. Opin. Chem. Biol.9(6), 674–679 (2005).
   PubMed Web of Science ®Google Scholar
• Bianco A, Kostarelos K, Partidos CD, Prato M. Biomedical applications of functionalised carbon nanotubes. Chem. Commun.5, 571–577 (2005).
   PubMed Web of Science ®Google Scholar
• Prato M, Kostarelos K, Bianco A. Functionalized carbon nanotubes in drug design and discovery. Accounts Chem. Res.41(1), 60–68 (2008).
   PubMed Web of Science ®Google Scholar
• Lu FS, Gu LR, Meziani MJ et al. Advances in bioapplications of carbon nanotubes. Adv. Mater.21(2), 139–152 (2009).
   Web of Science ®Google Scholar
• Kostarelos K, Bianco A, Prato M. Promises, facts and challenges for carbon nanotubes in imaging and therapeutics. Nat. Nanotechnol.4(10), 627–633 (2009).
   PubMed Web of Science ®Google Scholar
• Liu Z, Chen K, Davis C et al. Drug delivery with carbon nanotubes for in vivo cancer treatment. Cancer Res.68(16), 6652–6660 (2008).
   PubMed Web of Science ®Google Scholar
• Tasis D, Tagmatarchis N, Bianco A, Prato M. Chemistry of carbon nanotubes. Chem. Rev.106(3), 1105–1136 (2006).
   PubMed Web of Science ®Google Scholar
• Liu Y, Wu DC, Zhang WD et al. Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. Angew. Chem. Int. Edit.44(30), 4782–4785 (2005).
   PubMed Web of Science ®Google Scholar
• Lo MY, Lay CL, Lu XH, Liu Y. Finer structures of polyelectrolyte multilayers reflected by solution H-1 NMR. J. Phys. Chem. B.112(42), 13218–13224 (2008).
   Google Scholar
• Liu Z, Sun XM, Nakayama-Ratchford N, Dai HJ. Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery. ACS Nano.1(1), 50–56 (2007).
   PubMed Web of Science ®Google Scholar
• Liu Z, Winters M, Holodniy M, Dai HJ. siRNA delivery into human T cells and primary cells with carbon-nanotube transporters. Angew. Chem. Int. Edit.46(12), 2023–2027 (2007).
   PubMed Web of Science ®Google Scholar
• Ren YP, Pastorin G. Incorporation of hexamethylmelamine inside capped carbon nanotubes. Adv. Mater.20(11), 2031–2036 (2008).
   Web of Science ®Google Scholar
• Yanagi K, Miyata Y, Kataura H. Highly stabilized β-carotene in carbon nanotubes. Adv. Mater.18(2), 437–441 (2006).
   Web of Science ®Google Scholar
• Kam NWS, Liu Z, Dai HJ. Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway. Angew. Chem. Int. Edit.45(4), 577–581 (2006).
   PubMed Web of Science ®Google Scholar
• Lay CL, Liu HQ, Tan HR, Liu Y. Delivery of paclitaxel by physically loading onto poly(ethyleneglycol) (PEG)-graft carbon nanotubes for potent cancer therapeutics. Nanotechnology21(6), 065101 (2010).
   PubMed Web of Science ®Google Scholar
• Liu Z, Fan AC, Rakhra K et al. Supramolecular π-stacking of doxorubicin on carbon nanotubes for in vivo cancer therapy. Angew. Chem. Int. Edit.48(41), 7668–7672 (2009).
   PubMed Web of Science ®Google Scholar
• Liu Z, Tabakman SM, Chen Z, Dai HJ. Preparation of carbon nanotube bioconjugates for biomedical applications. Nat. Protoc.4(9), 1372–1382 (2009).
   PubMed Web of Science ®Google Scholar
• Kostarelos K, Lacerda L, Pastorin G et al. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nat. Nanotechnol.2(2), 108–113 (2007).
   PubMed Web of Science ®Google Scholar
• Schipper ML, Nakayama-Ratchford N, Davis CR et al. A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice. Nat. Nanotechnol.3(4), 216–221 (2008).
   PubMed Web of Science ®Google Scholar
• Liu Z, Davis C, Cai WB, He L, Chen XY, Dai HJ. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc. Natl Acad. Sci. USA105(5), 1410–1415 (2008).
   PubMed Web of Science ®Google Scholar
• Yang ST, Fernando KAS, Liu JH et al. Covalently PEGylated carbon nanotubes with stealth character in vivo. Small4(7), 940–944 (2008).
   PubMed Web of Science ®Google Scholar
• Chen JY, Chen SY, Zhao XR, Kuznetsova LV, Wong SS, Ojima I. Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery. J. Am. Chem. Soc.130(49), 16778–16785 (2008).
   PubMed Web of Science ®Google Scholar
• Yinghuai Z, Peng AT, Carpenter K, Maguire JA, Hosmane NS, Takagaki M. Substituted carborane-appended water-soluble single-wall carbon nanotubes: new approach to boron neutron capture therapy drug delivery. J. Am. Chem. Soc.127(27), 9875–9880 (2005).
   PubMed Web of Science ®Google Scholar
• Liu Z, Tabakman S, Welsher K, Dai HJ. Carbon nanotubes in biology and medicine: in vitro and in vivo detection, imaging and drug delivery. Nano Res.2(2), 85–120 (2009).
   PubMed Web of Science ®Google Scholar
• Hong SY, Tobias G, Al-Jamal KT et al. Filled and glycosylated carbon nanotubes for in vivo radioemitter localization and imaging. Nat. Mater.9(6), 485–490 (2010).
   PubMed Web of Science ®Google Scholar
• Samori C, Ali-Boucetta H, Sainz R et al. Enhanced anticancer activity of multi-walled carbon nanotube–methotrexate conjugates using cleavable linkers. Chem. Commun.46(9), 1494–1496 (2010).
   PubMed Web of Science ®Google Scholar
• Zhang XK, Meng LJ, Lu QG, Fei ZF, Dyson PJ. Targeted delivery and controlled release of doxorubicin to cancer cells using modified single wall carbon nanotubes. Biomaterials30(30), 6041–6047 (2009).
   PubMed Web of Science ®Google Scholar
• Kam NWS, Dai HJ. Carbon nanotubes as intracellular protein transporters: Generality and biological functionality. J. Am. Chem. Soc.127(16), 6021–6026 (2005).
   PubMed Web of Science ®Google Scholar
• Pantarotto D, Singh R, McCarthy D et al. Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew. Chem. Int. Edit.43(39), 5242–5246 (2004).
   PubMed Web of Science ®Google Scholar
• Singh R, Pantarotto D, McCarthy D et al. Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors. J. Am. Chem. Soc.127(12), 4388–4396 (2005).
   PubMed Web of Science ®Google Scholar
• Herrero MA, Toma FM, Al-Jamal KT et al. Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery. J. Am. Chem. Soc.131(28), 9843–9848 (2009).
   PubMed Web of Science ®Google Scholar
• Delogu LG, Magrini A, Bergamaschi A et al. Conjugation of antisense oligonucleotides to PEGylated carbon nanotubes enables efficient knockdown of PTPN22 in T lymphocytes. Bioconjugate Chem.20(3), 427–431 (2009).
   PubMed Web of Science ®Google Scholar
• Kam NWS, O’Connell M, Wisdom JA, Dai HJ. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc. Natl Acad. Sci. USA102(33), 11600–11605 (2005).
   PubMed Web of Science ®Google Scholar
• Kang B, Yu DC, Dai YD, Chang SQ, Chen D, Ding YT. Cancer-cell targeting and photoacoustic therapy using carbon nanotubes as ‘bomb’ agents. Small5(11), 1292–1301 (2009).
   PubMed Web of Science ®Google Scholar
• Podesta JE, Al-Jamal KT, Herrero MA et al. Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model. Small5(10), 1176–1185 (2009).
   PubMed Web of Science ®Google Scholar
• Liu Z, Cai WB, He LN et al.In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat. Nanotechnol.2(1), 47–52 (2007).
   PubMed Web of Science ®Google Scholar
• Ali-Boucetta H, Al-Jamal KT, McCarthy D, Prato M, Bianco A, Kostarelos K. Multiwalled carbon nanotube-doxorubicin supramolecular complexes for cancer therapeutics. Chem. Commun. (4), 459–461 (2008).
   PubMed Web of Science ®Google Scholar
• Murakami T, Ajima K, Miyawaki J, Yudasaka M, Iijima S, Shiba K. Drug-loaded carbon nanohorns: adsorption and release of dexamethasone in vitro. Mol. Pharmaceutics1(6), 399–405 (2004).
   PubMed Web of Science ®Google Scholar
• Chaudhuri P, Soni S, Sengupta S. Single-walled carbon nanotube-conjugated chemotherapy exhibits increased therapeutic index in melanoma. Nanotechnology21(2), 025102 (2010).
   Web of Science ®Google Scholar
• Chaudhuri P, Harfouche R, Soni S, Hentschel DM, Sengupta S. Shape effect of carbon nanovectors on angiogenesis. ACS Nano.4(1), 574–582 (2010).
   PubMed Web of Science ®Google Scholar
• Feazell RP, Nakayama-Ratchford N, Dai H, Lippard SJ. Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(iv) anticancer drug design. J. Am. Chem. Soc.129(27), 8438–8439 (2007).
   PubMed Web of Science ®Google Scholar
• Dhar S, Liu Z, Thomale J, Dai H, Lippard SJ. Targeted single-wall carbon nanotube-mediated Pt(iv) prodrug delivery using folate as a homing device. J. Am. Chem. Soc.130(34), 11467–11476 (2008).
   PubMed Web of Science ®Google Scholar
• Bhirde AA, Patel V, Gavard J et al. Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano3(2), 307–316 (2009).
   PubMed Web of Science ®Google Scholar
• Prencipe G, Tabakman SM, Welsher K et al. PEG branched polymer for functionalization of nanomaterials with ultralong blood circulation. J. Am. Chem. Soc.131(13), 4783–4787 (2009).
   PubMed Web of Science ®Google Scholar
• Lay CL, Liu HQ, Wu DC, Liu Y. Poly(ethylene glycol)-graft-hollow silica vesicles for drug delivery. Chem. Eur. J.16(10), 3001–3004 (2010).
   Google Scholar
• Lee JCM, Bermudez H, Discher BM et al. Preparation, stability, and in vitro performance of vesicles made with diblock copolymers. Biotechnol. Bioeng.73(2), 135–145 (2001).
   PubMed Web of Science ®Google Scholar
• Medical Applications of Liposomes. Lasic DD, Papahadjopoulos D (Eds). Elsevier Science, Amsterdam, The Netherlands (1998).
   Google Scholar
• Haag R, Kratz F. Polymer therapeutics: concepts and applications. Angew. Chem. Int. Edit.45(8), 1198–1215 (2006).
   PubMed Web of Science ®Google Scholar
• Wu W, Li R, Bian X et al. Covalently combining carbon nanotubes with anticancer agent: preparation and antitumor activity. ACS Nano.3(9), 2740–2750 (2009).
   PubMed Web of Science ®Google Scholar
• Zhou FF, Xing D, Wu BY, Wu SN, Ou ZM, Chen WR. New insights of transmembranal mechanism and subcellular localization of noncovalently modified single-walled carbon nanotubes. Nano Lett.10(5), 1677–1681 (2010).
   PubMed Web of Science ®Google Scholar
• Raffa V, Ciofani G, Nitodas S et al. Can the properties of carbon nanotubes influence their internalization by living cells? Carbon46, 1600–1610 (2008).
   Web of Science ®Google Scholar
• Antonelli A, Serafini S, Menotta M et al. Improved cellular uptake of functionalized single-walled carbon nanotubes. Nanotechnology21, 425101–425115 (2010).
   PubMed Web of Science ®Google Scholar
• Jin H, Heller DA, Sharma R, Strano MS. Size-dependent cellular uptake and expulsion of single-walled carbon nanotubes: single particle tracking and a generic uptake model for nanoparticles. ACS Nano.3(1), 149–158 (2009).
   PubMed Web of Science ®Google Scholar
• Singh R, Pantarotto D, Lacerda L et al. Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. Proc. Natl Acad. Sci. USA103(9), 3357–3362 (2006).
   PubMed Web of Science ®Google Scholar
• Cherukuri P, Gannon CJ, Leeuw TK et al. Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence. Proc. Natl Acad. Sci. USA103(50), 18882–18886 (2006).
   PubMed Web of Science ®Google Scholar
• Kagan VE, Konduru NV, Feng WH et al. Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Nat. Nanotechnol.5(5), 354–359 (2010).
   PubMed Web of Science ®Google Scholar