Where will insights into hippocampal activity in schizophrenia lead us?

References

• Harrison PJ. The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology174(1), 151–162 (2004).
   PubMed Web of Science ®Google Scholar
• Joyal CC, Laakso MP, Tiihonen J et al. A volumetric MRI study of the entorhinal cortex in first episode neuroleptic-naive schizophrenia. Biol. Psychiatry51(12), 1005–1007 (2002).
   PubMedGoogle Scholar
• Pantelis C, Velakoulis D, McGorry PD et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet361(9354), 281–288 (2003).
   PubMed Web of Science ®Google Scholar
• Narr KL, van Erp TG, Cannon TD et al. A twin study of genetic contributions to hippocampal morphology in schizophrenia. Neurobiol. Dis.11(1), 83–95 (2002).
   PubMed Web of Science ®Google Scholar
• Boos HB, Aleman A, Cahn W, Hulshoff Pol H, Kahn RS. Brain volumes in relatives of patients with schizophrenia: a meta-analysis. Arch. Gen. Psychiatry64(3), 297–304 (2007).
   PubMed Web of Science ®Google Scholar
• Falkai P, Honer WG, David S, Bogerts B, Majtenyi C, Bayer TA. No evidence for astrogliosis in brains of schizophrenic patients. A post-mortem study. Neuropathol. Appl. Neurobiol.25(1), 48–53 (1999).
   PubMedGoogle Scholar
• Eastwood SL, Harrison PJ. Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs. Mol. Psychiatry5(4), 425–432 (2000).
   PubMed Web of Science ®Google Scholar
• Benes FM. Evidence for altered trisynaptic circuitry in schizophrenia hippocampus. Biol. Psychiatry46, 589–599 (1999).
   PubMedGoogle Scholar
• Harrison PJ, Law AJ, Eastwood SL. Glutamate receptors and transporters in the hippocampus in schizophrenia. Ann. NY Acad. Sci.1003, 94–101 (2003).
   PubMedGoogle Scholar
• Harrison PJ, Eastwood SL. Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia. Lancet352, 1669–1673 (1998).
   PubMedGoogle Scholar
• Heckers S. Neuroimaging studies of the hippocampus in schizophrenia. Hippocampus11(5), 520–528 (2001).
   PubMed Web of Science ®Google Scholar
• Achim AM, Lepage M. Episodic memory-related activation in schizophrenia: meta-analysis. Br. J. Psychiatry187, 500–509 (2005).
   PubMed Web of Science ®Google Scholar
• O’Keefe J, Nadel L. The Hippocampus as a Cognitive Map. Oxford University Press, Oxford, UK (1978).
   Google Scholar
• Parslow DM, Rose FD, Brooks B et al. Allocentric spatial memory activation of the hippocampal formation measured with fMRI. Neuropsychologia18(3), 450–461 (2004).
   Google Scholar
• Antonova E, Parslow D, Brammer M, Dawson GR, Jackson SH, Morris RG. Age-related neural activity during allocentric spatial memory. Memory17(2), 125–143 (2009).
   PubMed Web of Science ®Google Scholar
• Langdon R, Coltheart M. Visual perspective-taking and schizotypy: evidence for a simulation-based account of mentalizing in normal adults. Cognition82(1), 1–26 (2001).
   PubMed Web of Science ®Google Scholar
• Vogeley K, Fink GR. Neural correlates of the first-person perspective. Trends Cogn. Sci.7(1), 38–42 (2003).
   PubMed Web of Science ®Google Scholar
• Chadwick P. Schizophrenia: The Positive Perspective. Psychology Press, Taylor & Francis Group, London, UK (1997).
   Google Scholar
• Bora E, Yucel M, Pantelis C. Theory of mind impairment in schizophrenia: meta-analysis. Schizophr. Res.109(1–3), 1–9 (2009).
   PubMed Web of Science ®Google Scholar
• Whitfield-Gabrieli S, Thermenos HW, Milanovic S et al. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc. Natl Acad. Sci. USA6(4), 1279–1284 (2009).
   Google Scholar
• Gray J. Integrating schizophrenia. Schizophr. Bull.24(2), 249–266 (1998).
   PubMed Web of Science ®Google Scholar
• Strange BA, Fletcher PC, Henson RN, Friston KJ, Dolan RJ. Segregating the functions of human hippocampus. Proc. Natl Acad. Sci. USA96(7), 4034–4039 (1999).
   PubMed Web of Science ®Google Scholar
• Schobel SA, Kelly MA, Corcoran CM et al. Anterior hippocampal and orbitofrontal cortical structural brain abnormalities in association with cognitive deficits in schizophrenia. Schizophr. Res.114(1–3), 110–118 (2009).
   PubMed Web of Science ®Google Scholar
• Hall J, Whalley HC, Marwick K et al. Hippocampal function in schizophrenia and bipolar disorder. Psychol. Med. DOI: 10.1017/S0033291709991000 (2009) (Epub ahead of print).
   Google Scholar
• Schobel SA, Lewandowski NM, Corcoran CM et al. Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders. Arch. Gen. Psychiatry66(9), 938–946 (2009).
   PubMed Web of Science ®Google Scholar
• Meisenzahl EV, Seifert D, Bottlender R et al. Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. Eur. Arch. Psychiatry Clin. Neurosci. (2009) (Epub ahead of print).
   PubMedGoogle Scholar
• Moller HJ. Systematic of psychiatric disorders between categorical and dimensional approaces: Kraepelin’s dichotomy and beyond. Eur. Arch. Psychiatry Clin. Neurosci.258(Suppl. 2), 48–73 (2008).
   PubMedGoogle Scholar
• Meyer SE, Bearden SE, Lux SR et al. The psychosis prodrome in adolescent patients viewed through the lends of DSM-IV. J. Child Adolesc. Psychopharmacol.15(3), 434–451 (2005).
   PubMed Web of Science ®Google Scholar
• Rosen JL, Miller TJ, D’Andrea JT, McGlashan TH, Woods SW. Comorbid diagnoses in patients meeting criteria for the schizophrenia prodrome. Schizophr. Res.85(1–3), 124–131 (2006).
   PubMed Web of Science ®Google Scholar
• Lee KH, Harris AW, Loughland CM, Williams LM. The five symptom dimensions and depression in schizophrenia. Psychopathology36(5), 226–233 (2003).
   PubMed Web of Science ®Google Scholar
• Zisook S, Nyer M, Kasckow J, Golshan S, Lehman D, Montross L. Depressive symptom patterns in patients with chronic schizophrenia and subsyndromal depression. Schizophr. Res.86(1–3), 226–233 (2006).
   PubMedGoogle Scholar
• Drake RJ, Pickles A, Bentall RP et al. The evolution of insight, paranoia and depression during early schizophrenia. Psychol. Med.34(2), 285–292 (2004).
   PubMed Web of Science ®Google Scholar
• Becker S, Wojtowics JM. A model of hippocampal neurogenesis in memory and mood disorders. Trends Cogn. Sci.2, 70–76 (2007).
   Google Scholar
• Hayashi F, Takashima N, Murayama A, Inokuchi K. Decreased postnatal neurogenesis in the hippocampus combined with stress experience during adolescence is accompanied by an enhanced incidence of behavioral pathologies in adult mice. Mol. Brain1, 22 (2008).
   PubMedGoogle Scholar
• Cerqueira JJ, Mailliet F, Almeida OF, Jay TM, Sousa N. The prefrontal cortex as a key target of the maladaptive response to stress. J. Neurosci.27(11), 2781–2787 (2007).
   PubMed Web of Science ®Google Scholar
• Jay TM, Witter MP. Distribution of hippocampus CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris leucoagglutinine. J. Comp. Neurol.313, 574–586 (1991).
   PubMedGoogle Scholar
• Bush G, Luu P, Posner M. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn. Sci.4, 215–222 (2000).
   PubMed Web of Science ®Google Scholar
• Râdulescu AR, Mujica-Parodi LR. A systems approach to prefrontal-limbic dysregulation in schizophrenia. Neuropsychobiology57(4), 206–216 (2008).
   PubMed Web of Science ®Google Scholar
• Sapolsky RM. Glucocorticoids and hippocampal atrophy in neuropsychiaric disorders. Arch. Gen. Psychiatry57(10), 925–935 (2000).
   PubMed Web of Science ®Google Scholar
• Radley J, Rocher A, Jandseen W, Hof P, McEwen B, Morrison J. Reversibility of atypical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp. Neurol.196, 199–203 (2005).
   PubMed Web of Science ®Google Scholar
• Kabat-Zinn J. Full Catastrophe Living: The Program of the Stress Reduction Clinic at the University of Massachusetts Medical Center. Delta, NY, USA (1990).
   Google Scholar
• Segal ZV, Teasdale JMG, Williams JD. Mindfulness-Based Cognitive Therapy for Depression. Guilford Press, NY, USA (2002).
   Google Scholar
• Van Hassel JH, Bloom LJ, Gonzalez AM. Anxiety management with schizophrenic outpatients. J. Clin. Psychol.38, 280–285 (1982).
   PubMedGoogle Scholar
• Falloon IR. Psychotherapy of schizophrenia. Br. J. Hosp. Med.48, 164–170 (1992).
   PubMedGoogle Scholar
• Linszen D, Lenior M, De Haan L, Dingemans P, Gersons B. Early intervention, untreated psychosis and the course of early schizophrenia. Br. J. Psychiatry172(Suppl.), 84–89 (1998).
   Web of Science ®Google Scholar
• Stein F, Nikolic S. Teaching stress management techniques to a schizophrenic patient. Am. J. Occup. Ther.43, 162–169 (1989).
   PubMed Web of Science ®Google Scholar
• Chadwick P, Taylor KN, Abba N. Mindfulness groups for people with psychosis. Behav. Cogn. Psychoth.33, 351–359 (2005).
   Web of Science ®Google Scholar