324
Views
64
CrossRef citations to date
0
Altmetric
Drug Profile

Donepezil in the treatment of patients with Alzheimer’s disease

Pages 591-598 | Published online: 09 Jan 2014

References

  • Bowen DM, Smith CB, White P, Davison AN. Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain99(3), 459–496 (1976).
  • Davies P, Maloney AJ. Selective loss of central cholinergic neurons in Alzheimer’s disease. Lancet2(8000), 1403 (1976).
  • Perry EK, Gibson PH, Blessed G, Perry RH, Tomlinson BE. Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue. J. Neurol. Sci.34(2), 247–265 (1977).
  • Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR. Alzheimer’s disease and senile dementia: loss of neurons in the basal forebrain. Science215(4537), 1237–1239 (1982).
  • Fink DM, Bores GM, Effland RC et al. Synthesis and evaluation of 5-amino-5,6,7,8-tetrahydroquinolinones as potential agents for the treatment of Alzheimer’s disease. J. Med. Chem.38(18), 3645–3651 (1995).
  • Sugimoto H, Tsuchiya Y, Sugumi H et al. Synthesis and structure–activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-(2-phthalimidoethyl)piperidine and related derivatives. J. Med. Chem.35(24), 4542–4548 (1992).
  • Thomsen T, Kewitz H. Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo. Life Sci.46(21), 1553–1558 (1990).
  • Tiseo PJ, Foley K, Friedhoff LT. An evaluation of the pharmacokinetics of donepezil HCl in patients with moderately to severely impaired renal function. Br. J. Clin. Pharmacol.46(Suppl. 1), 56–60 (1998).
  • Tiseo PJ, Foley K, Friedhoff LT. The effect of multiple doses of donepezil HCl on the pharmacokinetic and pharmacodynamic profile of warfarin. Br. J. Clin. Pharmacol.46(Suppl. 1), 45–50 (1998).
  • Tiseo PJ, Foley K, Friedhoff LT. Concurrent administration of donepezil HCl and theophylline: assessment of pharmacokinetic changes following multiple-dose administration in healthy volunteers. Br. J. Clin. Pharmacol.46(Suppl. 1), 35–39 (1998).
  • Tiseo PJ, Perdomo CA, Friedhoff LT. Concurrent administration of donepezil HCl and digoxin: assessment of pharmacokinetic changes. Br. J. Clin. Pharmacol.46(Suppl. 1), 40–44 (1998).
  • Tiseo PJ, Perdomo CA, Friedhoff LT. Concurrent administration of donepezil HCl and ketoconazole: assessment of pharmacokinetic changes following single and multiple doses. Br. J. Clin. Pharmacol.46(Suppl. 1), 30–34 (1998).
  • Tiseo PJ, Perdomo CA, Friedhoff LT. Concurrent administration of donepezil HCl and cimetidine: assessment of pharmacokinetic changes following single and multiple doses. Br. J. Clin. Pharmacol.46(Suppl. 1), 25–29 (1998).
  • Ohnishi A, Mihara M, Kamakura H et al. Comparison of the pharmacokinetics of E2020, a new compound for Alzheimer’s disease, in healthy young and elderly subjects. J. Clin. Pharmacol.33(11), 1086–1091 (1993).
  • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer’s disease. Donepezil Study Group. Neurology50(1), 136–145 (1998).
  • Burns A, Rossor M, Hecker J et al. The effects of donepezil in Alzheimer’s disease – results from a multinational trial. Dement. Geriatr. Cogn. Disord.10(3), 237–244 (1999).
  • Feldman H, Gauthier S, Hecker J, Vellas B, Subbiah P, Whalen E. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer’s disease. Neurology57(4), 613–620 (2001).
  • Mohs RC, Doody RS, Morris JC et al. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology57(3), 481–488 (2001).
  • Pratt RD, Perdomo CA, Surick IW, Ieni JR. Donepezil: tolerability and safety in Alzheimer’s disease. Int. J. Clin. Pract.56(9), 710–717 (2002).
  • Rogers SL, Doody RS, Mohs RC, Friedhoff LT. Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group. Arch. Intern. Med.158(9), 1021–1031 (1998).
  • Winblad B, Engedal K, Soininen H et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology57(3), 489–495 (2001).
  • Rogers SL, Friedhoff LT. The efficacy and safety of donepezil in patients with Alzheimer’s disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial. The Donepezil Study Group. Dementia7(6), 293–303 (1996).
  • Gauthier S, Feldman H, Hecker J et al. Efficacy of donepezil on behavioral symptoms in patients with moderate to severe Alzheimer’s disease. Int. Psychogeriatr.14(4), 389–404 (2002).
  • Geldmacher DS, Provenzano G, McRae T, Mastey V, Ieni JR. Donepezil is associated with delayed nursing home placement in patients with Alzheimer’s disease. J. Am. Geriatr. Soc.51(7), 937–944 (2003).
  • Feldman H, Gauthier S, Hecker J et al. Efficacy of donepezil on maintenance of activities of daily living in patients with moderate to severe Alzheimer’s disease and the effect on caregiver burden. J. Am. Geriatr. Soc.51(6), 737–744 (2003).
  • Wimo A, Winblad B, Shah SN, Chin W, Zhang R, McRae T. Impact of donepezil treatment for Alzheimer’s disease on caregiver time. Curr. Med. Res. Opin.20(8), 1221–1225 (2004).
  • Feldman H, Gauthier S, Hecker J et al. Efficacy and safety of donepezil in patients with more severe Alzheimer’s disease: a subgroup analysis from a randomized, placebo-controlled trial. Int. J. Geriatr. Psychiatry20(6), 559–569 (2005).
  • Homma A, Imai Y, Tago H et al. Donepezil treatment of patients with severe Alzheimer’s disease in a Japanese population: results from a 24-week, double-blind, placebo-controlled, randomized trial. Dement. Geriatr. Cogn. Disord.25(5), 399–407 (2008).
  • Winblad B, Kilander L, Eriksson S et al. Donepezil in patients with severe Alzheimer’s disease: double-blind, parallel-group, placebo-controlled study. Lancet367(9516), 1057–1065 (2006).
  • Black SE, Doody R, Li H et al. Donepezil preserves cognition and global function in patients with severe Alzheimer disease. Neurology69(5), 459–469 (2007).
  • Seow D, Gauthier S. Pharmacotherapy of Alzheimer disease. Can. J. Psychiatry52(10), 620–629 (2007).
  • Ancoli-Israel S, Amatniek J, Ascher S, Sadik K, Ramaswamy K. Effects of galantamine versus donepezil on sleep in patients with mild to moderate Alzheimer disease and their caregivers: a double-blind, head-to-head, randomized pilot study. Alzheimer Dis. Assoc. Disord.19(4), 240–245 (2005).
  • Wilcock G, Howe I, Coles H et al. A long-term comparison of galantamine and donepezil in the treatment of Alzheimer’s disease. Drugs Aging20(10), 777–789 (2003).
  • Bullock R, Bergman H, Touchon J et al. Effect of age on response to rivastigmine or donepezil in patients with Alzheimer’s disease. Curr. Med. Res. Opin22(3), 483–494 (2006).
  • Bullock R, Touchon J, Bergman H et al. Rivastigmine and donepezil treatment in moderate to moderately severe Alzheimer’s disease over a 2-year period. Curr. Med. Res. Opin.21(8), 1317–1327 (2005).
  • Winblad B, Cummings J, Andreasen N et al. A six-month double-blind, randomized, placebo-controlled study of a transdermal patch in Alzheimer’s disease – rivastigmine patch versus capsule. Int. J. Geriatr. Psychiatry22(5), 456–467 (2007).
  • Ellis JM. Cholinesterase inhibitors in the treatment of dementia. J. Am. Osteopath. Assoc.105(3), 145–158 (2005).
  • Birks J, Harvey RJ. Donepezil for dementia due to Alzheimer’s disease. Cochrane Database Syst. Rev.1, CD001190 (2006).
  • Kaduszkiewicz H, Zimmermann T, Beck-Bornholdt HP, van den Bussche H. Cholinesterase inhibitors for patients with Alzheimer’s disease: systematic review of randomised clinical trials. BMJ331(7512), 321–327 (2005).
  • Feldman H, Gauthier S, Hecker J et al. Economic evaluation of donepezil in moderate to severe Alzheimer disease. Neurology63(4), 644–650 (2004).
  • Courtney C, Farrell D, Gray R et al. Long-term donepezil treatment in 565 patients with Alzheimer’s disease (AD2000): randomised double-blind trial. Lancet363(9427), 2105–2115 (2004).
  • Birks J. Cholinesterase inhibitors for Alzheimer’s disease. Cochrane Database Syst. Rev.1, CD005593 (2006).
  • Bullock R, Dengiz A. Cognitive performance in patients with Alzheimer’s disease receiving cholinesterase inhibitors for up to 5 years. Int. J. Clin. Pract.59(7), 817–822 (2005).
  • Rogers SL, Doody RS, Pratt RD, Ieni JR. Long-term efficacy and safety of donepezil in the treatment of Alzheimer’s disease: final analysis of a US multicentre open-label study. Eur. Neuropsychopharmacol.10(3), 195–203 (2000).
  • Lopez OL, Becker JT, Saxton J, Sweet RA, Klunk W, DeKosky ST. Alteration of a clinically meaningful outcome in the natural history of Alzheimer’s disease by cholinesterase inhibition. J. Am. Geriatr. Soc.53(1), 83–87 (2005).
  • Cummings JL, McRae T, Zhang R. Effects of donepezil on neuropsychiatric symptoms in patients with dementia and severe behavioral disorders. Am. J. Geriatr. Psychiatry14(7), 605–612 (2006).
  • Tariot PN, Farlow MR, Grossberg GT, Graham SM, McDonald S, Gergel I. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. JAMA291(3), 317–324 (2004).
  • Orgogozo JM, Gilman S, Dartigues JF et al. Subacute meningoencephalitis in a subset of patients with AD after Ab42 immunization. Neurology61(1), 46–54 (2003).
  • Meguro M, Kasai M, Akanuma K, Ishii H, Yamaguchi S, Meguro K. Comprehensive approach of donepezil and psychosocial interventions on cognitive function and quality of life for Alzheimer’s disease: the Osaki-Tajiri Project. Age Ageing37(4), 469–473 (2008).
  • Mittelman MS, Brodaty H, Wallen AS, Burns A. A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression. Am. J. Geriatr. Psychiatry16(11), 893–904 (2008).
  • Onder G, Zanetti O, Giacobini E et al. Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer’s disease: randomised controlled trial. Br. J. Psychiatry187, 450–455 (2005).

Website

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.