Insight and suicidal behavior in first-episode schizophrenia

References

• McKenzie K, Serfaty M, Crawford M. Suicide in ethnic minority groups. Br. J. Psychiatry183, 100–101 (2003).
   PubMed Web of Science ®Google Scholar
• Maris RW. Suicide. Lancet360(9329), 319–326 (2002).
   PubMed Web of Science ®Google Scholar
• [No authors listed]. American Psychiatric Association. Practice guideline for the assessment and treatment of patients with suicidal behaviors. Am. J. Psychiatry160(Suppl. 11), 1–60 (2003).
   Web of Science ®Google Scholar
• McKeon R. Suicidal Behavior. Hogrefe and Huber Publishers, Cambridge, MA, USA (2009).
   Google Scholar
• Levi F, La VC, Lucchini F et al. Trends in mortality from suicide, 1965–1999. Acta Psychiatr. Scand.108(5), 341–349 (2003).
   PubMed Web of Science ®Google Scholar
• Mann JJ, Apter A, Bertolote J et al. Suicide prevention strategies: a systematic review. JAMA294(16), 2064–2074 (2005).
   PubMed Web of Science ®Google Scholar
• Burvill PW. Migrant suicide rates in Australia and in country of birth. Psychol. Med.28(1), 201–208 (1998).
   PubMed Web of Science ®Google Scholar
• Malenfant EC. Suicide in Canada’s immigrant population. Health Rep.15(2), 9–17 (2004).
   PubMedGoogle Scholar
• Pritchard C, Hansen L. Comparison of suicide in people aged 65–74 and 75+ by gender in England and Wales and the major Western countries 1979–1999. Int. J. Geriatr. Psychiatry20(1), 17–25 (2005).
   PubMed Web of Science ®Google Scholar
• Hawton K, van Heeringen K. Suicide. Lancet373(9672), 1372–1381 (2009).
   PubMed Web of Science ®Google Scholar
• Kerkhof JFM. Attempted suicide: patterns and trends. In: The International Handbook of Suicide and Attempted Suicide. Hawton K, van Heeringen K (Eds). John Wiley & Sons, Ltd, Hoboken, NJ, USA, 49–64 (2000).
   Google Scholar
• Silverman MM, Berman AL, Sanddal ND, O’Carroll PW, Joiner TE. Rebuilding the tower of Babel: a revised nomenclature for the study of suicide and suicidal behaviors. Part 1: background, rationale, and methodology. Suicide Life Threat. Behav.37(3), 248–263 (2007).
   PubMed Web of Science ®Google Scholar
• Kuo WH, Gallo JJ, Tien AY. Incidence of suicide ideation and attempts in adults: the 13-year follow-up of a community sample in Baltimore, Maryland. Psychol. Med.31(7), 1181–1191 (2001).
   PubMed Web of Science ®Google Scholar
• Borges G, Angst J, Nock MK, Ruscio AM, Walters EE, Kessler RC. A risk index for 12-month suicide attempts in the National Comorbidity Survey Replication (NCS-R). Psychol. Med.36(12), 1747–1757 (2006).
   PubMed Web of Science ®Google Scholar
• Kessler RC, Borges G, Walters EE. Prevalence of and risk factors for lifetime suicide attempts in the National Comorbidity Survey. Arch. Gen. Psychiatry56(7), 617–626 (1999).
   PubMed Web of Science ®Google Scholar
• Cavanagh JT, Carson AJ, Sharpe M, Lawrie SM. Psychological autopsy studies of suicide: a systematic review. Psychol. Med.33(3), 395–405 (2003).
   PubMed Web of Science ®Google Scholar
• Jollant F, Bellivier F, Leboyer M et al. Impaired decision making in suicide attempters. Am. J. Psychiatry162(2), 304–310 (2005).
   PubMed Web of Science ®Google Scholar
• Mann JJ, Arango VA, Avenevoli S et al. Candidate endophenotypes for genetic studies of suicidal behavior. Biol. Psychiatry65(7), 556–563 (2009).
   PubMed Web of Science ®Google Scholar
• Pompili M, Serafini G, Innamorati M et al. The hypothalamic–pituitary–adrenal axis and serotonin abnormalities: a selective overview for the implications of suicide prevention. Eur. Arch. Psychiatry Clin. Neurosci.260(8), 583–600 (2010).
   PubMed Web of Science ®Google Scholar
• Carlborg A, Jokinen J, Nordstrom AL, Jonsson EG, Nordstrom P. CSF 5-HIAA, attempted suicide and suicide risk in schizophrenia spectrum psychosis. Schizophr. Res.112(1–3), 80–85 (2009).
   PubMed Web of Science ®Google Scholar
• Carlborg A, Winnerback K, Jonsson EG, Jokinen J, Nordstrom P. Suicide in schizophrenia. Expert Rev. Neurother.10(7), 1153–1164 (2010).
   PubMed Web of Science ®Google Scholar
• Olie E, Picot MC, Guillaume S, Abbar M, Courtet P. Measurement of total serum cholesterol in the evaluation of suicidal risk. J. Affect. Disord.133(1–2), 234–238 (2011).
   PubMed Web of Science ®Google Scholar
• Tidemalm D, Runeson B, Waern M et al. Familial clustering of suicide risk: a total population study of 11.4 million individuals. Psychol. Med.1, 1–8 (2011).
   Google Scholar
• von Borczyskowski A, Lindblad F, Vinnerljung B, Reintjes R, Hjern A. Familial factors and suicide: an adoption study in a Swedish National Cohort. Psychol. Med.41(4), 749–758 (2011).
   PubMed Web of Science ®Google Scholar
• Saetre P, Lundmark P, Wang A et al. The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case–control study and meta-analysis. Am. J. Med. Genet. B Neuropsychiatr. Genet.153B(2), 387–396 (2010).
   PubMed Web of Science ®Google Scholar
• Zai CC, Manchia M, De Luca V et al. The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis. Int. J. Neuropsychopharmacol.30, 1–6 (2011).
   Google Scholar
• Murphy TM, Ryan M, Foster T et al. Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B and NTRK2 polymorphisms. Behav. Brain Funct.7, 22 (2011).
   PubMed Web of Science ®Google Scholar
• Bertolote JM, Fleischmann A, De Leo D, Wasserman D. Psychiatric diagnoses and suicide: revisiting the evidence. Crisis25(4), 147–155 (2004).
   PubMedGoogle Scholar
• Duberstein PR, Conwell Y. Personality disorders and completed suicide: a methodological and conceptual review. Clin. Psychol.4(4), 359–376 (1997).
   Google Scholar
• Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time? Arch. Gen. Psychiatry64(10), 1123–1131 (2007).
   PubMed Web of Science ®Google Scholar
• Caldwell CB, Gottesman II. Schizophrenics kill themselves too: a review of risk factors for suicide. Schizophr. Bull.16(4), 571–589 (1990).
   PubMed Web of Science ®Google Scholar
• Palmer BA, Pankratz VS, Bostwick JM. The lifetime risk of suicide in schizophrenia: a reexamination. Arch. Gen. Psychiatry62(3), 247–253 (2005).
   PubMed Web of Science ®Google Scholar
• Bolton C, Gooding P, Kapur N, Barrowclough C, Tarrier N. Developing psychological perspectives of suicidal behaviour and risk in people with a diagnosis of schizophrenia: we know they kill themselves but do we understand why? Clin. Psychol. Rev.27(4), 511–536 (2007).
   PubMed Web of Science ®Google Scholar
• Williams JMG, Crane C, Barnhofer T, Duggan D. Psychology and suicidal behaviour: elaborating the entrapment model. In: Prevention and Treatment of Suicidal Beahviour. Hawton K (Ed.). Oxford University Press, Oxford, UK, 71–89 (2005).
   Google Scholar
• Hawton K, Sutton L, Haw C, Sinclair J, Deeks JJ. Schizophrenia and suicide: systematic review of risk factors. Br. J. Psychiatry187, 9–20 (2005).
   PubMed Web of Science ®Google Scholar
• Montross LP, Zisook S, Kasckow J. Suicide among patients with schizophrenia: a consideration of risk and protective factors. Ann. Clin. Psychiatry17(3), 173–182 (2005).
   PubMedGoogle Scholar
• Pompili M, Lester D, Grispini A et al. Completed suicide in schizophrenia: evidence from a case control study. Psychiatry Res.167(3), 251–257 (2009).
   PubMed Web of Science ®Google Scholar
• McGirr A, Turecki G. What is specific to suicide in schizophrenia disorder? Demographic, clinical and behavioural dimensions. Schizophr. Res.98(1–3), 217–224 (2008).
   PubMed Web of Science ®Google Scholar
• Pompili M, Amador XF, Girardi P et al. Suicide risk in schizophrenia: learning from the past to change the future. Ann. Gen. Psychiatry6, 10 (2007).
   PubMedGoogle Scholar
• Heila H, Isometsa ET, Henriksson MM, Heikkinen ME, Marttunen MJ, Lonnqvist JK. Suicide and schizophrenia: a nationwide psychological autopsy study on age- and sex-specific clinical characteristics of 92 suicide victims with schizophrenia. Am. J. Psychiatry154(9), 1235–1242 (1997).
   PubMed Web of Science ®Google Scholar
• McGirr A, Tousignant M, Routhier D et al. Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: a case–control study. Schizophr. Res.84(1), 132–143 (2006).
   PubMed Web of Science ®Google Scholar
• Westermeyer JF, Harrow M, Marengo JT. Risk for suicide in schizophrenia and other psychotic and nonpsychotic disorders. J. Nerv. Ment. Dis.179(5), 259–266 (1991).
   PubMed Web of Science ®Google Scholar
• Nordentoft M. Prevention of suicide and attempted suicide in Denmark. Epidemiological studies of suicide and intervention studies in selected risk groups. Dan. Med. Bull.54(4), 306–369 (2007).
   PubMed Web of Science ®Google Scholar
• Evensen J, Rossberg JI, Haahr U et al. Contrasting monosymptomatic patients with hallucinations and delusions in first-episode psychosis patients: a five-year longitudinal follow-up study. Psychopathology44(2), 90–97 (2011).
   PubMed Web of Science ®Google Scholar
• Madsen T, Nordentoft M. Suicidal changes in patients with first episode psychosis: clinical predictors of increasing suicidal tendency in the early treatment phase. Early Interv. Psychiatry doi:10.1111/j.1751-7893.2011.00284.x (2011) (Epub ahead of print).
   PubMedGoogle Scholar
• Harkavy-Friedman JM, Kimhy D, Nelson EA, Venarde DF, Malaspina D, Mann JJ. Suicide attempts in schizophrenia: the role of command auditory hallucinations for suicide. J. Clin. Psychiatry64(8), 871–874 (2003).
   PubMed Web of Science ®Google Scholar
• Zisook S, Byrd D, Kuck J, Jeste DV. Command hallucinations in outpatients with schizophrenia. J. Clin. Psychiatry56(10), 462–465 (1995).
   PubMed Web of Science ®Google Scholar
• Kim CH, Jayathilake K, Meltzer HY. Hopelessness, neurocognitive function, and insight in schizophrenia: relationship to suicidal behavior. Schizophr. Res.60(1), 71–80 (2003).
   PubMed Web of Science ®Google Scholar
• Nangle JM, Clarke S, Morris DW et al. Neurocognition and suicidal behaviour in an Irish population with major psychotic disorders. Schizophr. Res.85(1–3), 196–200 (2006).
   PubMed Web of Science ®Google Scholar
• Potkin SG, Anand R, Alphs L, Fleming K. Neurocognitive performance does not correlate with suicidality in schizophrenic and schizoaffective patients at risk for suicide. Schizophr. Res.59(1), 59–66 (2003).
   PubMed Web of Science ®Google Scholar
• Barrett EA, Sundet K, Simonsen C et al. Neurocognitive functioning and suicidality in schizophrenia spectrum disorders. Compr. Psychiatry52(2), 156–163 (2011).
   PubMed Web of Science ®Google Scholar
• Pompili M, Serafini G, Innamorati M et al. Suicide risk in first episode psychosis: a selective review of the current literature. Schizophr. Res.129(1), 1–11 (2011).
   PubMed Web of Science ®Google Scholar
• Dutta R, Murray RM, Hotopf M, Allardyce J, Jones PB, Boydell J. Reassessing the long-term risk of suicide after a first episode of psychosis. Arch. Gen. Psychiatry67(12), 1230–1237 (2010).
   PubMed Web of Science ®Google Scholar
• McGirr A, Renaud J, Bureau A, Seguin M, Lesage A, Turecki G. Impulsive–aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide. Psychol. Med.38(3), 407–417 (2008).
   PubMed Web of Science ®Google Scholar
• Verdoux H, Liraud F, Gonzales B, Assens F, Abalan F, van Os J. Predictors and outcome characteristics associated with suicidal behaviour in early psychosis: a two-year follow-up of first-admitted subjects. Acta Psychiatr. Scand.103(5), 347–354 (2001).
   PubMed Web of Science ®Google Scholar
• Larsen TK, Melle I, Auestad B et al. Substance abuse in first-episode non-affective psychosis. Schizophr. Res.88(1–3), 55–62 (2006).
   PubMed Web of Science ®Google Scholar
• Romm KL, Rossberg JI, Berg AO et al. Depression and depressive symptoms in first episode psychosis. J. Nerv. Ment. Dis.198(1), 67–71 (2010).
   PubMed Web of Science ®Google Scholar
• Haug E, Melle I, Andreassen OA et al. The association between anomalous self-experience and suicidality in first-episode schizophrenia seems mediated by depression. Compr. Psychiatry doi:10.1016/j.comppsych.2011.07.005 (2011) (Epub ahead of print).
   PubMedGoogle Scholar
• Bertelsen M, Jeppesen P, Petersen L et al. Suicidal behaviour and mortality in first-episode psychosis: the OPUS trial. Br. J. Psychiatry Suppl.51, S140–S146 (2007).
   PubMedGoogle Scholar
• Robinson J, Cotton S, Conus P, Schimmelmann BG, McGorry P, Lambert M. Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis. Aust. NZ J. Psychiatry43(2), 149–157 (2009).
   PubMed Web of Science ®Google Scholar
• Barrett EA, Sundet K, Faerden A et al. Suicidality before and in the early phases of first episode psychosis. Schizophr. Res.119(1–3), 11–17 (2010).
   PubMed Web of Science ®Google Scholar
• Nielssen OB, Large MM. Untreated psychotic illness in survivors of violent suicide attempts. Early Interv. Psychiatry3, 116–122 (2009).
   PubMed Web of Science ®Google Scholar
• Clarke M, Whitty P, Browne S et al. Suicidality in first episode psychosis. Schizophr. Res.86(1–3), 221–225 (2006).
   PubMed Web of Science ®Google Scholar
• Foley S, Jackson D, McWilliams S et al. Suicidality prior to presentation in first-episode psychosis. Early Interv. Psychiatry2, 242–246 (2008).
   PubMed Web of Science ®Google Scholar
• Harvey SB, Dean K, Morgan C et al. Self-harm in first-episode psychosis. Br. J. Psychiatry192(3), 178–184 (2008).
   PubMed Web of Science ®Google Scholar
• Altamura AC, Bassetti R, Bignotti S, Pioli R, Mundo E. Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study. Schizophr. Res.60(1), 47–55 (2003).
   PubMed Web of Science ®Google Scholar
• Bakst S, Rabinowitz J, Bromet EJ. Antecedents and patterns of suicide behavior in first-admission psychosis. Schizophr. Bull.36(4), 880–889 (2009).
   PubMed Web of Science ®Google Scholar
• Nordentoft M, Jeppesen P, Abel M et al. OPUS study: suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis. One-year follow-up of a randomised controlled trial. Br. J. Psychiatry Suppl.43, S98–S106 (2002).
   Google Scholar
• Preti A, Meneghelli A, Pisano A, Cocchi A. Risk of suicide and suicidal ideation in psychosis: results from an Italian multi-modal pilot program on early intervention in psychosis. Schizophr. Res.113(2–3), 145–150 (2009).
   PubMed Web of Science ®Google Scholar
• Melle I, Johannesen JO, Friis S et al. Early detection of the first episode of schizophrenia and suicidal behavior. Am. J. Psychiatry163(5), 800–804 (2006).
   PubMed Web of Science ®Google Scholar
• David AS. Insight and psychosis. Br. J. Psychiatry156, 798–808 (1990).
   PubMed Web of Science ®Google Scholar
• Amador XF, Flaum M, Andreasen NC et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch. Gen. Psychiatry51(10), 826–836 (1994).
   PubMed Web of Science ®Google Scholar
• Pini S, Cassano GB, Dell’Osso L, Amador XF. Insight into illness in schizophrenia, schizoaffective disorder, and mood disorders with psychotic features. Am. J. Psychiatry158(1), 122–125 (2001).
   PubMed Web of Science ®Google Scholar
• Amador XF, Gorman JM. Psychopathologic domains and insight in schizophrenia. Psychiatr. Clin. North Am.21(1), 27–42 (1998).
   PubMed Web of Science ®Google Scholar
• Cuesta MJ, Peralta V, Zarzuela A. Reappraising insight in psychosis. Multi-scale longitudinal study. Br. J. Psychiatry177, 233–240 (2000).
   PubMed Web of Science ®Google Scholar
• Wiffen BD, Rabinowitz J, Lex A, David AS. Correlates, change and ‘state or trait’ properties of insight in schizophrenia. Schizophr. Res.122(1–3), 94–103 (2010).
   PubMed Web of Science ®Google Scholar
• Mintz AR, Dobson KS, Romney DM. Insight in schizophrenia: a meta-analysis. Schizophr. Res.61(1), 75–88 (2003).
   PubMed Web of Science ®Google Scholar
• Olfson M, Marcus SC, Wilk J, West JC. Awareness of illness and nonadherence to antipsychotic medications among persons with schizophrenia. Psychiatr. Serv.57(2), 205–211 (2006).
   PubMed Web of Science ®Google Scholar
• Lysaker PH, Bryson GJ, Bell MD. Insight and work performance in schizophrenia. J. Nerv. Ment. Dis.190(3), 142–146 (2002).
   PubMed Web of Science ®Google Scholar
• Carroll A, Pantelis C, Harvey C. Insight and hopelessness in forensic patients with schizophrenia. Aust. NZ J. Psychiatry38(3), 169–173 (2004).
   PubMed Web of Science ®Google Scholar
• Hasson-Ohayon I, Kravetz S, Roe D, David AS, Weiser M. Insight into psychosis and quality of life. Compr. Psychiatry47(4), 265–269 (2006).
   PubMed Web of Science ®Google Scholar
• Valiente C, Provencio M, Espinosa R, Chaves C, Fuentenebro F. Predictors of subjective well-being in patients with paranoid symptoms: is insight necessarily advantageous? Psychiatry Res.189(2), 190–194 (2011).
   PubMed Web of Science ®Google Scholar
• Amador XF, Friedman JH, Kasapis C, Yale SA, Flaum M, Gorman JM. Suicidal behavior in schizophrenia and its relationship to awareness of illness. Am. J. Psychiatry153(9), 1185–1188 (1996).
   PubMed Web of Science ®Google Scholar
• Crumlish N, Whitty P, Kamali M et al. Early insight predicts depression and attempted suicide after 4 years in first-episode schizophrenia and schizophreniform disorder. Acta Psychiatr. Scand.112(6), 449–455 (2005).
   PubMed Web of Science ®Google Scholar
• Schwartz RC, Smith SD. Suicidality and psychosis: the predictive potential of symptomatology and insight into illness. J. Psychiatr. Res.38(2), 185–191 (2004).
   PubMed Web of Science ®Google Scholar
• Kao YC, Liu YP. Suicidal behavior and insight into illness among patients with schizophrenia spectrum disorders. Psychiatr. Q.82(3), 207–220 (2011).
   PubMed Web of Science ®Google Scholar
• Restifo K, Harkavy-Friedman JM, Shrout PE. Suicidal behavior in schizophrenia: a test of the demoralization hypothesis. J. Nerv. Ment. Dis.197(3), 147–153 (2009).
   PubMed Web of Science ®Google Scholar
• Bourgeois M, Swendsen J, Young F et al. Awareness of disorder and suicide risk in the treatment of schizophrenia: results of the international suicide prevention trial. Am. J. Psychiatry161(8), 1494–1496 (2004).
   PubMed Web of Science ®Google Scholar
• Steblaj A, Tavcar R, Dernovsek MZ. Predictors of suicide in psychiatric hospital. Acta Psychiatr. Scand.100(5), 383–388 (1999).
   PubMed Web of Science ®Google Scholar
• Lysaker PH, Roe D, Yanos PT. Toward understanding the insight paradox: internalized stigma moderates the association between insight and social functioning, hope, and self-esteem among people with schizophrenia spectrum disorders. Schizophr. Bull.33(1), 192–199 (2007).
   PubMed Web of Science ®Google Scholar
• Linden M, Godemann F. The differentiation between ‘lack of insight’ and ‘dysfunctional health beliefs’ in schizophrenia. Psychopathology40(4), 236–241 (2007).
   PubMed Web of Science ®Google Scholar
• Crisp AH, Gelder MG, Rix S, Meltzer HI, Rowlands OJ. Stigmatisation of people with mental illnesses. Br. J. Psychiatry177, 4–7 (2000).
   PubMed Web of Science ®Google Scholar
• Angermeyer MC, Dietrich S. Public beliefs about and attitudes towards people with mental illness: a review of population studies. Acta Psychiatr. Scand.113(3), 163–179 (2006).
   PubMed Web of Science ®Google Scholar
• Iqbal Z, Birchwood M, Chadwick P, Trower P. Cognitive approach to depression and suicidal thinking in psychosis. 2. Testing the validity of a social ranking model. Br. J. Psychiatry177, 522–528 (2000).
   PubMed Web of Science ®Google Scholar
• Karatzias T, Gumley A, Power K, O’Grady M. Illness appraisals and self-esteem as correlates of anxiety and affective comorbid disorders in schizophrenia. Compr. Psychiatry48(4), 371–375 (2007).
   PubMed Web of Science ®Google Scholar
• Watson PW, Garety PA, Weinman J et al. Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions. Psychol. Med.36(6), 761–770 (2006).
   PubMed Web of Science ®Google Scholar
• Fialko L, Freeman D, Bebbington PE et al. Understanding suicidal ideation in psychosis: findings from the Psychological Prevention of Relapse in Psychosis (PRP) trial. Acta Psychiatr. Scand.114(3), 177–186 (2006).
   PubMed Web of Science ®Google Scholar
• Staring AB, van der Gaag M, van den Berge M, Duivenvoorden HJ, Mulder CL. Stigma moderates the associations of insight with depressed mood, low self-esteem, and low quality of life in patients with schizophrenia spectrum disorders. Schizophr. Res.115(2–3), 363–369 (2009).
   PubMed Web of Science ®Google Scholar
• Lopez-Morinigo JD, Ramos-Rios R, David AS, Dutta R. Insight in schizophrenia and risk of suicide: a systematic update. Compr. Psychiatry doi:10.1016/j.comppsych.2011.05.015 (2011) (Epub ahead of print).
   PubMedGoogle Scholar
• Barrett EA, Sundet K, Faerden A et al. Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis. Schizophr. Res.123(2–3), 257–262 (2010).
   PubMed Web of Science ®Google Scholar
• Pompili M, Lester D, Innamorati M, Tatarelli R, Girardi P. Assessment and treatment of suicide risk in schizophrenia. Expert Rev. Neurother.8(1), 51–74 (2008).
   PubMedGoogle Scholar