40
Views
1
CrossRef citations to date
0
Altmetric
Key Paper Evaluation

Gene-expression analysis for prediction of RTS,S-induced protection in humans

Pages 465-469 | Published online: 09 Jan 2014

References

  • Plotkin SA. Vaccines: the fourth century. Clin. Vaccine Immunol.16(12), 1709–1719 (2009).
  • Haynes BF, Pantaleo G, Fauci AS. Toward an understanding of the correlates of protective immunity to HIV infection. Science271(5247), 324–328 (1996).
  • Kaufmann SH, Parida SK. Tuberculosis in Africa: learning from pathogenesis for biomarker identification. Cell Host Microbe4(3), 219–228 (2008).
  • Frevert U. Sneaking in through the back entrance: the biology of malaria liver stages. Trends Parasitol.20(9), 417–424 (2004).
  • Kwiatkowski D, Bate CA, Scragg IG et al. The malarial fever response – pathogenesis, polymorphism and prospects for intervention. Ann. Trop. Med. Parasitol.91(5), 533–542 (1997).
  • Snow RW, Trape JF, Marsh K. The past, present and future of childhood malaria mortality in Africa. Trends Parasitol.17(12), 593–597 (2001).
  • Gupta S, Snow RW, Donnelly CA, Marsh K, Newbold C. Immunity to non-cerebral severe malaria is acquired after one or two infections. Nat. Med.5(3), 340–343 (1999).
  • Plowe CV, Alonso P, Hoffman SL. The potential role of vaccines in the elimination of falciparum malaria and the eventual eradication of malaria. J. Infect. Dis.200(11), 1646–1649 (2009).
  • Alonso PL. Malaria: deploying a candidate vaccine (RTS,S/AS02A) for an old scourge of humankind. Int. Microbiol.9(2), 83–93 (2006).
  • Garcon N, Heppner DG, Cohen J. Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant. Expert Rev. Vaccines2(2), 231–238 (2003).
  • Polhemus ME, Remich SA, Ogutu BR et al. Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area. PLoS One4(7), e6465 (2009).
  • Alonso PL, Sacarlal J, Aponte JJ et al. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet364(9443), 1411–1420 (2004).
  • Moorthy VS, Ballou WR. Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data. Malar. J.8(1), 312 (2009).
  • Overstreet MG, Cockburn IA, Chen YC, Zavala F. Protective CD8 T cells against Plasmodium liver stages: immunobiology of an ‘unnatural’ immune response. Immunol. Rev.225, 272–283 (2008).
  • Hill AV. Pre-erythrocytic malaria vaccines: towards greater efficacy. Nat. Rev. Immunol.6(1), 21–32 (2006).
  • Pinder M, Reece WH, Plebanski M et al. Cellular immunity induced by the recombinant Plasmodium falciparum malaria vaccine, RTS,S/AS02, in semi-immune adults in The Gambia. Clin. Exp. Immunol.135(2), 286–293 (2004).
  • Kester KE, Cummings JF, Ofori-Anyinam O et al. Randomized, double-blind, Phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection. J. Infect. Dis.200(3), 337–346 (2009).
  • Kester KE, Cummings JF, Ockenhouse CF et al. Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naive adults at the Walter Reed Army Institute of Research. Vaccine26(18), 2191–2202 (2008).
  • Stoute JA, Slaoui M, Heppner DG et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group. N. Engl. J. Med.336(2), 86–91 (1997).
  • Bejon P, Andrews L, Andersen RF et al. Calculation of liver-to-blood inocula, parasite growth rates, and pre-erythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites. J. Infect. Dis.191(4), 619–626 (2005).
  • Vahey MT, Wang Z, Kester KE et al. Expression of genes associated with immunoproteasome processing of major histocompatibility complex peptides is indicative of protection with adjuvanted RTS,S malaria vaccine. J. Infect. Dis.201(4), 580–589 (2010).
  • Rieckmann KH. Human immunization with attenuated sporozoites. Bull. World Health Organ.68(Suppl.), 13–16 (1990).
  • Strehl B, Seifert U, Kruger E et al. Interferon-γ, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing. Immunol. Rev.207, 19–30 (2005).
  • Cheng Y. Toward an atomic model of the 26S proteasome. Curr. Opin. Struct. Biol.19(2), 203–208 (2009).
  • Jacobsen M, Repsilber D, Gutschmidt A et al. Deconfounding microarray analysis – independent measurements of cell type proportions used in a regression model to resolve tissue heterogeneity bias. Methods Inf. Med.45(5), 557–563 (2006).
  • Repsilber D, Kern S, Telaar A et al. Biomarker discovery in heterogeneous tissue samples -taking the in-silicode-confounding approach. BMC Bioinformatics11, 27 (2010).
  • Pulendran B. Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology. Nat. Rev. Immunol.9(10), 741–747 (2009).
  • Querec TD, Akondy RS, Lee EK et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol.10(1), 116–125 (2009).
  • Gaucher D, Therrien R, Kettaf N et al. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J. Exp. Med.205(13), 3119–3131 (2008).
  • Zhu W, Higgs BW, Morehouse C et al. A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children. Vaccine28(16), 2865–2876 (2010).

Website

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.