References
- Martinon F, Mayor A, Tschopp J. The inflammasomes: guardians of the body. Annu. Rev. Immunol.27, 229–265 (2009).
- He X, Mekasha S, Mavrogiorgos N, Fitzgerald KA, Lien E, Ingalls RR. Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome. J. Immunol.184(10), 5743–5754 (2010).
- Mishra BB, Moura-Alves P, Sonawane A et al. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell. Microbiol.12(8), 1046–1063 (2010).
- McElvania TE, Tekippe E, Allen IC et al. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. PLoS ONE5(8), e12320 (2010).
- McNeela EA, Burke A, Neill DR et al. Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. PLoS Pathog.6(11), e1001191 (2010).
- Craven RR, Gao X, Allen IC et al. Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS ONE4(10), e7446 (2009).
- Thomas PG, Dash P, Aldridge JR Jr et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity30(4), 566–575 (2009).
- Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J. Exp. Med.203(7), 1685–1691 (2006).
- Meng G, Zhang F, Fuss I, Kitani A, Strober W. A mutation in the NLRP3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity30(6), 860–874 (2009).
- Kolls JK. Th17 cells in mucosal immunity and tissue inflammation. Semin. Immunopathol.32(1), 1–2 (2010).
- Ye P, Rodriguez FH, Kanaly S et al. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J. Exp. Med.194(4), 519–527 (2001).
- Dunne A, Ross PJ, Pospisilova E et al. Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J. Immunol.185(3), 1711–1719 (2010).
- Ma CS, Chew GY, Simpson N et al. Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J. Exp. Med.205(7), 1551–1557 (2008).
- Schneider BE, Korbel D, Hagens K et al. A role for IL-18 in protective immunity against Mycobacterium tuberculosis. Eur. J. Immunol.40(2), 396–405 (2010).
- Sharp FA, Ruane D, Claass B et al. Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. Proc. Natl Acad. Sci. USA106(3), 870–875 (2009).
Website
- Acute Respiratory Infections www.who.int/vaccine_research/diseases/ari/en/index.html