371
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Rab1A-Mediated Exosomal Sorting of miR-200c Enhances Breast Cancer Lung Metastasis

, , , , ORCID Icon, , , , , , , & ORCID Icon show all
Pages 403-419 | Received 05 Jan 2023, Accepted 21 Apr 2023, Published online: 30 May 2023

References

  • Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7–33. doi:10.3322/caac.21708
  • Riggio AI, Varley KE, Welm AL. The lingering mysteries of metastatic recurrence in breast cancer. Br J Cancer. 2021;124(1):13–26. doi:10.1038/s41416-020-01161-4
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30. doi:10.3322/caac.21442
  • Jin L, Han B, Siegel E, et al. Breast cancer lung metastasis: molecular biology and therapeutic implications. Cancer Biol Ther. 2018;19(10):858–868. doi:10.1080/15384047.2018.1456599
  • Qiu X, Li Z, Han X, et al. Tumor-derived nanovesicles promote lung distribution of the therapeutic nanovector through repression of Kupffer cell-mediated phagocytosis. Theranostics. 2019;9(9):2618–2636. doi:10.7150/thno.32363
  • Yuan X, Qian N, Ling S, et al. Breast cancer exosomes contribute to pre-metastatic niche formation and promote bone metastasis of tumor cells. Theranostics. 2021;11(3):1429–1445. doi:10.7150/thno.45351
  • Teng Y, Xu F, Zhang X, et al. Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12. Mol Ther. 2021;29(8):2424–2440. doi:10.1016/j.ymthe.2021.05.005
  • Xu J, Zhang J, Zhang Z, et al. Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction. Cell Death Dis. 2021;12(4):373. doi:10.1038/s41419-021-03664-1
  • Kia V, Paryan M, Mortazavi Y, et al. Evaluation of exosomal miR-9 and miR-155 targeting PTEN and DUSP14 in highly metastatic breast cancer and their effect on low metastatic cells. J Cell Biochem. 2019;120(4):5666–5676. doi:10.1002/jcb.27850
  • Zhou B, Xu K, Zheng X, et al. Application of exosomes as liquid biopsy in clinical diagnosis. Signal Transduct Target Ther. 2020;5(1):144. doi:10.1038/s41392-020-00258-9
  • Lai CP, Mardini O, Ericsson M, et al. Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter. ACS Nano. 2014;8(1):483–494. doi:10.1021/nn404945r
  • Teng Y, Ren Y, Hu X, et al. MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Nat Commun. 2017;8(1):14448. doi:10.1038/ncomms14448
  • Fong MY, Zhou W, Liu L, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17(2):183–194. doi:10.1038/ncb3094
  • Teng Y, Ren Y, Sayed M, et al. Plant-derived exosomal MicroRNAs shape the gut microbiota. Cell Host Microbe. 2018;24(5):637–652.e8. doi:10.1016/j.chom.2018.10.001
  • Xiang X, Zhuang X, Ju S, et al. miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. Oncogene. 2011;30(31):3440–3453. doi:10.1038/onc.2011.54
  • Roshanzamir F, Robinson JL, Cook D, et al. Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures. Proc Natl Acad Sci U S A. 2022;119(35):e2205456119. doi:10.1073/pnas.2205456119
  • Dykxhoorn DM. MicroRNAs and metastasis: little RNAs go a long way. Cancer Res. 2010;70(16):6401–6406. doi:10.1158/0008-5472.CAN-10-1346
  • Elrebehy MA, Al-Saeed S, Gamal S, et al. miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: a spotlight on signaling pathways interplay - a review. Int J Biol Macromol. 2022;214:583–600. doi:10.1016/j.ijbiomac.2022.06.134
  • Chen M, Lei N, Tian W, et al. Recent advances of non-coding RNAs in ovarian cancer prognosis and therapeutics. Ther Adv Med Oncol. 2022;14:17588359221118010. doi:10.1177/17588359221118010
  • Manavalan TT, Teng Y, Litchfield LM, et al. Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells. PLoS One. 2013;8(4):e62334. doi:10.1371/journal.pone.0062334
  • Navarro-Manzano E, Luengo-Gil G, González-Conejero R, et al. Prognostic and predictive effects of tumor and plasma miR-200c-3p in locally advanced and metastatic breast cancer. Cancers. 2022;14(10):2390. doi:10.3390/cancers14102390
  • Chaffer CL, Marjanovic N, Lee T, et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell. 2013;154(1):61–74. doi:10.1016/j.cell.2013.06.005
  • Zhang G, Zhang W, Li B, et al. MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer. Breast Cancer Res. 2017;19(1):73. doi:10.1186/s13058-017-0858-x
  • Xue B, Chuang C-H, Prosser HM, et al. miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts. Genes Dev. 2021;35(15–16):1109–1122. doi:10.1101/gad.347344.120
  • Bai T, Dong DS, Pei L. Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer. Oncol Rep. 2014;31(5):2293–2297. doi:10.3892/or.2014.3090
  • Teng Y, Girvan AC, Casson LK, et al. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 2007;67(21):10491–10500. doi:10.1158/0008-5472.CAN-06-4206
  • Xu H, Qian M, Zhao B, et al. Inhibition of RAB1A suppresses epithelial-mesenchymal transition and proliferation of triple-negative breast cancer cells. Oncol Rep. 2017;37(3):1619–1626. doi:10.3892/or.2017.5404
  • Wang YN, Yamaguchi H, Huo L, et al. The translocon Sec61β localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus. J Biol Chem. 2010;285(49):38720–38729. doi:10.1074/jbc.M110.158659
  • Wijshake T, Zou Z, Chen B, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118(5).
  • Cendrowicz E, Sas Z, Bremer E, et al. The role of macrophages in cancer development and therapy. Cancers. 2021;13(8):1946. doi:10.3390/cancers13081946
  • Teng Y, Mu J, Xu F, et al. Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death. Cell Host Microbe. 2022;30(7):944–960.e8. doi:10.1016/j.chom.2022.05.005
  • Noy R, Pollard JW. Tumor-associated macrophages: from mechanisms to therapy. Immunity. 2014;41(1):49–61. doi:10.1016/j.immuni.2014.06.010
  • Janjigian YY, Kawazoe A, Yañez P, et al. The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer. Nature. 2021;600(7890):727–730. doi:10.1038/s41586-021-04161-3
  • Wesolowski J, Tankiewicz-Kwedlo A, Pawlak D. Modern immunotherapy in the treatment of triple-negative breast cancer. Cancers. 2022;14(16):3860. doi:10.3390/cancers14163860
  • Emens LA, Adams S, Barrios CH, et al. First-line atezolizumab plus nab-paclitaxel for unresectable, locally advanced, or metastatic triple-negative breast cancer: iMpassion130 final overall survival analysis. Ann Oncol. 2021;32(8):983–993. doi:10.1016/j.annonc.2021.05.355