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International Journal of Chronic Obstructive Pulmonary Disease Volume 18, 2023 - Issue
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ORIGINAL RESEARCH

COPD Exacerbations, Costs, and Health Care Resource Utilization Before and After Initiation of Fluticasone Furoate/Umeclidinium/Vilanterol in Routine Care in the USA

Nicola A Hanania1 Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USAORCID Iconhttps://orcid.org/0000-0003-3087-9530View further author information
ORCID Icon,
Scott H Bunner2 Optum, Eden Prairie, MN, USAORCID Iconhttps://orcid.org/0000-0003-3280-5164View further author information
ORCID Icon,
Lindsay GS Bengtson2 Optum, Eden Prairie, MN, USAORCID Iconhttps://orcid.org/0000-0002-5370-4090View further author information
ORCID Icon,
Afisi S Ismaila3 Value Evidence and Outcomes, GSK, Collegeville, PA, USA;4 Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, CanadaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2876-8308View further author information
ORCID Icon &
Michael Bogart5 US Value Evidence & Outcomes, GSK, Research Triangle Park, NC, USAORCID Iconhttps://orcid.org/0000-0002-1681-9710View further author information
ORCID Icon
Pages 407-418 | Received 17 Jun 2022, Accepted 15 Mar 2023, Published online: 24 Mar 2023

References

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  • Global Initiative for Chronic Obstructive Lung Disease (GOLD) [Homepage on the Internet]. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease - 2022 report; 2022. Available from: https://goldcopd.org/2022-gold-reports/. Accessed March 7, 2022.
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  • Mannino D, Bogart M, Wu B, et al. Adherence and persistence to once-daily single-inhaler versus multiple-inhaler triple therapy among patients with chronic obstructive pulmonary disease in the USA: a real-world study. Respir Med. 2022;197:106807. doi:10.1016/j.rmed.2022.106807
  • US Food and Drug Administration (FDA) [Internet]. Trelegy Ellipta (fluticasone furoate 100 mcg, umeclidinium 62.5 mcg, and vilanterol 25 mcg) inhalation powder approval letter; 2017. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2017/209482Orig1s000Approv.pdf. Accessed June 9, 2022.
  • Bogart M, Stanford RH, Reinsch T, et al. Clinical characteristics and medication patterns in patients with COPD prior to initiation of triple therapy with ICS/LAMA/LABA: a retrospective study. Resp Med. 2018;142:73–80. doi:10.1016/j.rmed.2018.07.009
  • Wu EQ, Birnbaum HG, Cifaldi M, Kang Y, Mallet D, Colice G. Development of a COPD severity score. Curr Med Res Opin. 2006;22(9):1679–1687. doi:10.1185/030079906X115621
  • Lipson DA, Barnhart F, Brealey N, et al. Once-daily single-inhaler triple versus dual therapy in patients with COPD. N Engl J Med. 2018;378(18):1671–1680. doi:10.1056/NEJMoa1713901
  • Ferguson GT, Brown N, Compton C, et al. Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials. Respir Res. 2020;21(1):131. doi:10.1186/s12931-020-01360-w
  • Stanford RH, Engel-Nitz NM, Bancroft T, Essoi B. The identification and cost of acute chronic obstructive pulmonary disease exacerbations in a United States population healthcare claims database. COPD. 2020;17(5):499–508. doi:10.1080/15412555.2020.1817357

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