Effects of Z-VaD-Ala-Asp-Fluoromethyl Ketone (Z-VAD-FMK) and Acetyl-Asp-Glu-Val-Asp-Aldehyde(Ac-DEVD-CHO) on Inflammation and Mucus Secretion in Mice Exposed to Cigarette Smoke

References

• Chronic Obstructive Pulmonary Disease Group of Chinese Thoracic Society. Chronic Obstructive Pulmonary Disease Committee of Chinese Association of Chest Physician. Zhonghua Jie He He Hu Xi Za Zhi. 2021;44(3):170–205. doi:10.3760/cma.j.cn112147-20210109-00031
   PubMedGoogle Scholar
• Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2020 REPORT)[EB/OL]; 2019. Available from: https://goldcopd.org/goldreports/. Accessed January 20, 2023.
   Google Scholar
• Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol. 2009;4:435–459. doi:10.1146/annurev.pathol.4.110807.092145
   PubMed Web of Science ®Google Scholar
• Lin VY, Kaza N, Birket SE, et al. Excess mucus viscosity and airway dehydration impact COPD airway clearance. Eur Respir J. 2020;55(1):1900419. doi:10.1183/13993003.00419-2019
   PubMed Web of Science ®Google Scholar
• Maté I, Martínez de Toda I, Arranz L, Álvarez-Sala JL, De la Fuente M. Accelerated immunosenescence, oxidation and inflammation lead to a higher biological age in COPD patients. Exp Gerontol. 2021;154:111551. doi:10.1016/j.exger.2021.111551
   Web of Science ®Google Scholar
• Kim V, Evans CM, Dickey BF. Dawn of a new era in the diagnosis and treatment of airway mucus dysfunction. Am J Respir Crit Care Med. 2019;199(2):133–134. doi:10.1164/rccm.201808-1444ED
   PubMed Web of Science ®Google Scholar
• Chen J, Fang WX, Li SJ, Xiao SX, Li HJ, Situ YL. Protective effect of ginsenoside rd on lipopolysaccharide-induced acute lung injury through its anti-inflammatory and anti-oxidative activity. World J Tradit Chin Med. 2021;7:383–390. doi:10.4103/wjtcm.wjtcm_12_21
   Google Scholar
• Chen R, Liang Y, Ip MSM, Zhang KY, Mak JCW. Amelioration of cigarette smoke-induced mucus hypersecretion and viscosity by dendrobium officinale polysaccharides in vitro and in vivo. Oxid Med Cell Longev. 2020;2020:8217642. doi:10.1155/2020/8217642
   Web of Science ®Google Scholar
• Pouwels SD, Zijlstra GJ, van der Toorn M, et al. Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice. Am J Physiol Lung Cell Mol Physiol. 2016;310(4):L377–L386. doi:10.1152/ajplung.00174.2015
   PubMed Web of Science ®Google Scholar
• Pauwels NS, Bracke KR, Dupont LL, et al. Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD. Eur Respir J. 2011;38(5):1019–1028. doi:10.1183/09031936.00158110
   PubMed Web of Science ®Google Scholar
• Mahalanobish S, Dutta S, Saha S, Sil PC. Melatonin induced suppression of ER stress and mitochondrial dysfunction inhibited NLRP3 inflammasome activation in COPD mice. Food Chem Toxicol. 2020;144:111588. doi:10.1016/j.fct.2020.111588
   PubMed Web of Science ®Google Scholar
• Donovan C, Kim RY, Galvao I, et al. Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion. Immunol Cell Biol. 2022;100(4):235–249. doi:10.1111/imcb.12537
   Web of Science ®Google Scholar
• Shirasuna K, Takano H, Seno K, et al. Palmitic acid induces interleukin-1β secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells. J Reprod Immunol. 2016;116:104–112. doi:10.1016/j.jri.2016.06.001
   Web of Science ®Google Scholar
• Bautista MV, Chen Y, Ivanova VS, Rahimi MK, Watson AM, Rose MC. IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells. J Immunol. 2009;183(3):2159–2166. doi:10.4049/jimmunol.0803022
   Web of Science ®Google Scholar
• Bayne K. Revised guide for the care and use of laboratory animals available. Am Physiol Soc Physiol. 1996;39(4):199–211.
   Google Scholar
• Harijith A, Ebenezer DL, Natarajan V. Reactive oxygen species at the crossroads of inflammasome and inflammation. Front Physiol. 2014;5:352. doi:10.3389/fphys.2014.00352
   PubMed Web of Science ®Google Scholar
• Wattanachayakul P, Rujirachun P, Charoenngam N, Ungprasert P. Chronic obstructive pulmonary disease (COPD) is associated with a higher level of serum uric acid. A systematic review and meta-analysis. Adv Respir Med. 2020;88(3):215–222. doi:10.5603/ARM.2020.0119
   Web of Science ®Google Scholar
• Zhou F, Li DF, Yuan L, et al. 两种不同方法建立的小鼠慢性阻塞性肺疾病模型的比较研究 [A comparative study of two chronic obstructive pulmonary disease mouse models established by different methods]. Zhonghua Jie He He Hu Xi Za Zhi. 2019;42(5):367–371. doi:10.3760/cma.j.issn.1001-0939.2019.05.010.Chinese.
   Google Scholar
• Zhang G, Chang MJ, Huang JN, et al. KGF-2对COPD小鼠保护性作用的免疫学研究 [Immunological study on the protective effect of KGF-2 on COPD mice]. Fudan Univ J Med Sci. 2018;45(5):638–643. Chinese.
   Google Scholar
• Churg A, Zhou S, Wang X, Wang R, Wright JL. The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling. Am J Respir Cell Mol Biol. 2009;40(4):482–490. doi:10.1165/rcmb.2008-0038OC
   PubMed Web of Science ®Google Scholar
• Lappalainen U, Whitsett JA, Wert SE, Tichelaar JW, Bry K. Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung. Am J Respir Cell Mol Biol. 2005;32(4):311–318. doi:10.1165/rcmb.2004-0309OC
   PubMed Web of Science ®Google Scholar
• Guo JL, Cui XQ, Rong Y, et al. [The role of interleukin-1β on the pulmonary fibrosis in mice exposed to crystalline silica]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013;31(7):481–486.
   Google Scholar
• Ritter M, Straubinger K, Schmidt S, et al. Functional relevance of NLRP3 inflammasome-mediated interleukin (IL)-1β during acute allergic airway inflammation. Clin Exp Immunol. 2014;178(2):212–223. doi:10.1111/cei.12400
   Web of Science ®Google Scholar
• Faner R, Sobradillo P, Noguera A, et al. The inflammasome pathway in stable COPD and acute exacerbations. ERJ Open Res. 2016;2(3):00002–2016. doi:10.1183/23120541.00002-2016
   PubMedGoogle Scholar
• Dinarello CA. Proinflammatory cytokines. Chest. 2000;118(2):503–508. doi:10.1378/chest.118.2.503
   PubMed Web of Science ®Google Scholar
• Yang W, Ni H, Wang H, Gu H. NLRP3 inflammasome is essential for the development of chronic obstructive pulmonary disease. Int J Clin Exp Pathol. 2015;8(10):13209–13216.
   PubMed Web of Science ®Google Scholar
• Novartis. Safety And efficacy of multiple doses of canakinumab (ACZ885) in chronic obstructive pulmonary disease (COPD) patients. ClinicalTrialsgov Identifier: NCT00581945 US National Institutes of Health, ClinicalTrialsgov [online]. Available from: http://wwwclinicaltrialsgov. Accessed August 7, 2014.
   Google Scholar
• LLC M. A study to evaluate the efficacy of MEDI8968 in chronic obstructive pulmonary disease (SPRING). ClinicalTrialsgov Identifier: NCT01448850 US National Institutes of Health, ClinicalTrialsgov [online]. Available from: http://wwwclinicaltrialsgov. Accessed August 7, 2014.
   Google Scholar
• Wang S, Xiong L, Deng X, et al. [Effect of aminophylline and simvastatin on airway inflammation and mucus hypersecretion in rats with chronic obstructive pulmonary disease]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016;41(1):37–43. doi:10.11817/j.issn.1672-7347.2016.01.006
   Google Scholar
• Nachmias N, Langier S, Brzezinski RY, et al. NLRP3 inflammasome activity is upregulated in an in-vitro model of COPD exacerbation. PLoS One. 2019;14(5):e0214622. doi:10.1371/journal.pone.0214622
   PubMed Web of Science ®Google Scholar
• de Oca MM, Halbert RJ, Lopez MV, et al. The chronic bronchitis phenotype in subjects with and without COPD: the PLATINO study. Eur Respir J. 2012;40(1):28–36. doi:10.1183/09031936.00141611
   PubMed Web of Science ®Google Scholar
• Wang H, Yang T, Wang T, et al. Phloretin attenuates mucus hypersecretion and airway inflammation induced by cigarette smoke. Int Immunopharmacol. 2018;55:112–119. doi:10.1016/j.intimp.2017.12.009
   PubMed Web of Science ®Google Scholar
• Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA. The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development. Am J Respir Crit Care Med. 2016;193(6):662–672. doi:10.1164/rccm.201511-2210OC
   PubMed Web of Science ®Google Scholar
• Radicioni G, Ceppe A, Ford AA, et al. Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2021;9(11):1241–1254. doi:10.1016/S2213-2600(21)
   PubMed Web of Science ®Google Scholar
• Hao D, Li Y, Shi J, Jiang J. Baicalin alleviates chronic obstructive pulmonary disease through regulation of HSP72-mediated JNK pathway. Mol Med. 2021;27(1):53. doi:10.1186/s10020-021-00309-z
   Web of Science ®Google Scholar