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ORIGINAL RESEARCH

RNA-Sequencing and Bioinformatics Analysis of Exosomal Long Noncoding RNAs Revealed a Novel ceRNA Network in Stable COPD

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Pages 1995-2007 | Received 24 Apr 2023, Accepted 24 Jul 2023, Published online: 11 Sep 2023

References

  • Agusti A, Vogelmeier C, Faner R. COPD 2020: changes and challenges. Am J Physiol Lung Cell Mol Physiol. 2020;319(5):L879–L883. doi:10.1152/ajplung.00429.2020
  • Wang C, Li Z, Liu Y, et al. Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets. Theranostics. 2021;11(8):3996–4010. doi:10.7150/thno.56035
  • Mathivanan S, Ji H, Simpson RJ. Exosomes: extracellular organelles important in intercellular communication. J Proteomics. 2010;73(10):1907–1920. doi:10.1016/j.jprot.2010.06.006
  • Pegtel DM, Gould SJ. Exosomes. Annu Rev Biochem. 2019;88:487–514. doi:10.1146/annurev-biochem-013118-111902
  • Kopp F, Mendell JT. Functional classification and experimental dissection of long noncoding RNAs. Cell. 2018;172(3):393–407. doi:10.1016/j.cell.2018.01.011
  • Poulet C, Njock M-S, Moermans C, et al. Exosomal long non-coding RNAs in lung diseases. Int J Mol Sci. 2020;21(10):3580. doi:10.3390/ijms21103580
  • Zhang R, Xia Y, Wang Z, et al. Serum long non coding RNA MALAT-1 protected by exosomes is up-regulated and promotes cell proliferation and migration in non-small cell lung cancer. Biochem Biophys Res Commun. 2017;490(2):406–414. doi:10.1016/j.bbrc.2017.06.055
  • Song L, Peng J, Guo X. Exosomal lncRNA TCONS_00064356 derived from injured alveolar epithelial type II cells affects the biological characteristics of mesenchymal stem cells. Life Sci. 2021;278:119568. doi:10.1016/j.lfs.2021.119568
  • Kalluri R, LeBleu VS. The biology, function, and biomedical applications of exosomes. Science. 2020;367(6478):6977. doi:10.1126/science.aau6977
  • Wu DM, Deng SH, Liu T, et al. TGF-beta-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression. Cancer Med. 2018;7(10):5118–5129.
  • Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med. 2004;350(26):2645–2653. doi:10.1056/NEJMoa032158
  • Saetta M, Turato G, Baraldo S, et al. Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med. 2000;161(3 Pt 1):1016–1021. doi:10.1164/ajrccm.161.3.9907080
  • Barnes PJ. Cellular and molecular mechanisms of chronic obstructive pulmonary disease. Clin Chest Med. 2014;35(1):71–86. doi:10.1016/j.ccm.2013.10.004
  • Lemichez E, Lecuit M, Nassif X, et al. Breaking the wall: targeting of the endothelium by pathogenic bacteria. Nat Rev Microbiol. 2010;8(2):93–104. doi:10.1038/nrmicro2269
  • Hunter KA, Garlick PJ, Broom I, et al. Effects of smoking and abstention from smoking on fibrinogen synthesis in humans. Clin Sci (Lond). 2001;100(4):459–465. doi:10.1042/cs1000459
  • Marklund S, Bui KL, Nyberg A. Measuring and monitoring skeletal muscle function in COPD: current perspectives. Int J Chron Obstruct Pulmon Dis. 2019;14:1825–1838. doi:10.2147/COPD.S178948
  • Andre S, Conde B, Fragoso E, et al. COPD and cardiovascular disease. Pulmonology. 2019;25(3):168–176. doi:10.1016/j.pulmoe.2018.09.006
  • Hou W, Hu S, Li C, et al. Cigarette smoke induced lung barrier dysfunction, EMT, and tissue remodeling: a possible link between COPD and lung cancer. Biomed Res Int. 2019;2019:2025636. doi:10.1155/2019/2025636
  • Cheong A, Lingutla R, Mager J. Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020;38:119147. doi:10.1016/j.gep.2020.119147
  • Kirsch VC, Orgler C, Braig S, et al. The cytotoxic natural product vioprolide a targets nucleolar protein 14, which is essential for ribosome biogenesis. Angew Chem Int Ed Engl. 2020;59(4):1595–1600. doi:10.1002/anie.201911158
  • Verma G, Bowen A, Gheibi S, et al. Ribosomal biogenesis regulator DIMT1 controls beta-cell protein synthesis, mitochondrial function, and insulin secretion. J Biol Chem. 2022;298(3):101692. doi:10.1016/j.jbc.2022.101692
  • Hiregange DG, Rivalta A, Yonath A, et al. Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia. FEBS Open Bio. 2022;12(7):1419–1434. doi:10.1002/2211-5463.13444
  • Zhu Q, Tao B, Chen H, et al. Rcl1 depletion impairs 18S pre-rRNA processing at the A1-site and up-regulates a cohort of ribosome biogenesis genes in zebrafish. Nucleic Acids Res. 2021;49(10):5743–5759. doi:10.1093/nar/gkab381
  • Karim L, Kosmider B, Bahmed K. Mitochondrial ribosomal stress in lung diseases. Am J Physiol Lung Cell Mol Physiol. 2022;322(4):L507–L517. doi:10.1152/ajplung.00078.2021
  • Farre-Garros R, Lee JY, Natanek SA, et al. Quadriceps miR-542-3p and −5p are elevated in COPD and reduce function by inhibiting ribosomal and protein synthesis. J Appl Physiol. 2019;126(6):1514–1524. doi:10.1152/japplphysiol.00882.2018
  • Wang X, Wang Y, Sun F, et al. Novel LncRNA ZFHX4-AS1 as a potential prognostic biomarker that affects the immune microenvironment in ovarian cancer. Front Oncol. 2022;12:945518. doi:10.3389/fonc.2022.945518
  • Zheng H, Qian X, Tian W, Cao L. Exploration of the common gene characteristics and molecular mechanism of Parkinson’s disease and crohn’s disease from. Transcript Data Brain Sci. 2022;12:6.
  • Najafzadeh L, Mahmoudi M, Ebadi M, et al. Co-expression network analysis reveals key genes related to ankylosing spondylitis arthritis disease: computational and experimental validation. Iran J Biotechnol. 2021;19(1):e2630. doi:10.30498/IJB.2021.2630
  • O’Farrell HE, Bowman RV, Fong KM, et al. Plasma extracellular vesicle miRNAs can identify lung cancer, current smoking status, and stable COPD. Int J Mol Sci. 2021;22(11):5803. doi:10.3390/ijms22115803
  • Zhu K, Zhou S, Xu A, et al. Microbiota imbalance contributes to COPD deterioration by enhancing IL-17a production via miR-122 and miR-30a. Mol Ther Nucleic Acids. 2020;22:520–529. doi:10.1016/j.omtn.2020.09.017
  • Chen P, Jiang P, Chen J, et al. XIST promotes apoptosis and the inflammatory response in CSE-stimulated cells via the miR-200c-3p/EGR3 axis. BMC Pulm Med. 2021;21(1):215. doi:10.1186/s12890-021-01582-8
  • Prakash YS, Pabelick CM, Sieck GC. Mitochondrial dysfunction in airway disease. Chest. 2017;152(3):618–626. doi:10.1016/j.chest.2017.03.020