Preserved Ratio Impaired Spirometry (PRISm): A Global Epidemiological Overview, Radiographic Characteristics, Comorbid Associations, and Differentiation from Chronic Obstructive Pulmonary Disease

References

• Lange P, Celli B, Agusti A, et al. Lung-function trajectories leading to chronic obstructive pulmonary disease. N Engl J Med. 2015;373(2):111–122. doi:10.1056/NEJMoa1411532
   PubMed Web of Science ®Google Scholar
• Celli BR, Wedzicha JA, Drazen JM. Update on clinical aspects of chronic Obstructive pulmonary disease. N Engl J Med. 2019;381(13):1257–1266. doi:10.1056/NEJMra1900500
   PubMed Web of Science ®Google Scholar
• Wan ES, Castaldi PJ, Cho MH, et al. Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res. 2014;15(1):89. doi:10.1186/s12931-014-0089-y
   PubMed Web of Science ®Google Scholar
• Kaise T, Sakihara E, Tamaki K, et al. Prevalence and characteristics of individuals with preserved ratio impaired spirometry (PRISm) and/or impaired lung function in Japan: the OCEAN study. Int J Chron Obstruct Pulmon Dis. 2021;16:2665–2675. doi:10.2147/COPD.S322041
   PubMed Web of Science ®Google Scholar
• Washio Y, Sakata S, Fukuyama S, et al. Risks of mortality and airflow limitation in Japanese individuals with preserved ratio impaired spirometry. Am J Respir Crit Care Med. 2022;206(5):563–572. doi:10.1164/rccm.202110-2302OC
   PubMed Web of Science ®Google Scholar
• Wijnant SRA, De Roos E, Kavousi M, et al. Trajectory and mortality of preserved ratio impaired spirometry: the Rotterdam Study. Eur Respir J. 2020;55(1):1901217. doi:10.1183/13993003.01217-2019
   PubMed Web of Science ®Google Scholar
• Wan ES, Fortis S, Regan EA, et al. Longitudinal phenotypes and mortality in preserved ratio impaired spirometry in the COPDGene study. Am J Respir Crit Care Med. 2018;198(11):1397–1405. doi:10.1164/rccm.201804-0663OC
   PubMed Web of Science ®Google Scholar
• Marott JL, Ingebrigtsen TS, Colak Y, Vestbo J, Lange P. Trajectory of preserved ratio impaired spirometry: natural history and long-term prognosis. Am J Respir Crit Care Med. 2021;204(8):910–920. doi:10.1164/rccm.202102-0517OC
   PubMed Web of Science ®Google Scholar
• Higbee DH, Granell R, Davey Smith G, Dodd JW. Prevalence, risk factors, and clinical implications of preserved ratio impaired spirometry: a UK Biobank cohort analysis. Lancet Respir Med. 2022;10(2):149–157. doi:10.1016/S2213-2600(21)00369-6
   PubMed Web of Science ®Google Scholar
• Xiao T, Wijnant SRA, Licher S, et al. Lung function impairment and the risk of incident dementia: the Rotterdam Study. J Alzheimers Dis. 2021;82(2):621–630. doi:10.3233/JAD-210162
   PubMed Web of Science ®Google Scholar
• Ariza-Prota MA, Pando-Sandoval A, García-Clemente M, et al. Primary pulmonary botryomycosis: a bacterial lung infection mimicking lung cancer [Case study]. Int J Tuberc Lung Dis. 2013;17(7):992–994. doi:10.5588/ijtld.12.0054
   PubMed Web of Science ®Google Scholar
• Shiraishi Y, Shimada T, Tanabe N, et al. The prevalence and physiological impacts of centrilobular and paraseptal emphysema on computed tomography in smokers with preserved ratio impaired spirometry. ERJ Open Res. 2022;8(2):00063–2022. doi:10.1183/23120541.00063-2022
   PubMedGoogle Scholar
• Kim J, Lee CH, Lee HY, Kim H. Association between comorbidities and preserved ratio impaired spirometry: using the Korean national health and nutrition examination survey IV-VI. Respiration. 2022;101(1):25–33. doi:10.1159/000517599
   PubMedGoogle Scholar
• Wan ES, Hokanson JE, Regan EA, et al. Significant spirometric transitions and preserved ratio impaired spirometry among ever smokers. Chest. 2022;161(3):651–661. doi:10.1016/j.chest.2021.09.021
   PubMed Web of Science ®Google Scholar
• Mkorombindo T, Balkissoon R. Journal club-respiratory impairment with a preserved spirometric ratio. Chronic Obstr Pulm Dis. 2022;9(1):103–110. doi:10.15326/jcopdf.2022.0285
   PubMed Web of Science ®Google Scholar
• Perez-Padilla R, Montes de Oca M, Thirion-Romero I, et al. Trajectories of spirometric patterns, obstructive and PRISm, in a population-based cohort in Latin America. Int J Chron Obstruct Pulmon Dis. 2023;18:1277–1285. doi:10.2147/COPD.S406208
   PubMed Web of Science ®Google Scholar
• Li D, Ruan Z, Xie S, Xuan S, Zhao H, Wu B. The relationship between preserved ratio impaired spirometry and mortality in the myocardial infarction survivors: a population-based cohort study. BMC Cardiovasc Disord. 2023;23(1):331. doi:10.1186/s12872-023-03352-2
   PubMedGoogle Scholar
• Chen Y, Horne SL, Dosman JA. Body weight and weight gain related to pulmonary function decline in adults: a six year follow up study. Thorax. 1993;48(4):375–380. doi:10.1136/thx.48.4.375
   PubMed Web of Science ®Google Scholar
• Sun C, Kovacs P, Guiu-Jurado E. Genetics of obesity in East Asians. Front Genet. 2020;11:575049. doi:10.3389/fgene.2020.575049
   PubMed Web of Science ®Google Scholar
• Ogden CL, Carroll MD, Fryar CD, Flegal KM. Prevalence of obesity among adults and youth: United States, 2011–2014. NCHS Data Brief. 2015;219:1–8.
   PubMedGoogle Scholar
• Yang JJ, Yu D, Wen W, et al. Tobacco smoking and mortality in Asia: a pooled meta-analysis. JAMA Network Open. 2019;2(3):e191474. doi:10.1001/jamanetworkopen.2019.1474
   PubMed Web of Science ®Google Scholar
• Reitsma MB, Fullman N, Ng M; Collaborators GBDT. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015. Lancet. 2017;389(10082):1885–1906. doi:10.1016/S0140-6736(17)30819-X
   PubMed Web of Science ®Google Scholar
• Ratanachina J, De Matteis S, Cullinan P, Burney P. Pesticide exposure and lung function: a systematic review and meta-analysis. Occup Med. 2020;70(1):14–23. doi:10.1093/occmed/kqz161
   Google Scholar
• van Horne YO, Farzan SF, Razafy M, Johnston JE. Respiratory and allergic health effects in children living near agriculture: a review. Sci Total Environ. 2022;832:155009. doi:10.1016/j.scitotenv.2022.155009
   PubMed Web of Science ®Google Scholar
• Nordgren TM, Bailey KL. Pulmonary health effects of agriculture. Curr Opin Pulm Med. 2016;22(2):144–149. doi:10.1097/MCP.0000000000000247
   PubMed Web of Science ®Google Scholar
• Al-Qerem W, Ling J. Pulmonary function tests in Egyptian schoolchildren in rural and urban areas. East Mediterr Health J. 2018;24(4):325–332. doi:10.26719/2018.24.4.325
   PubMed Web of Science ®Google Scholar
• Priftis KN, Mantzouranis EC, Anthracopoulos MB. Asthma symptoms and airway narrowing in children growing up in an urban versus rural environment. J Asthma. 2009;46(3):244–251. doi:10.1080/02770900802647516
   PubMed Web of Science ®Google Scholar
• Whitrow MJ, Harding S. Ethnic differences in adolescent lung function: anthropometric, socioeconomic, and psychosocial factors. Am J Respir Crit Care Med. 2008;177(11):1262–1267. doi:10.1164/rccm.200706-867OC
   PubMed Web of Science ®Google Scholar
• Korotzer B, Ong S, Hansen JE. Ethnic differences in pulmonary function in healthy nonsmoking Asian-Americans and European-Americans. Am J Respir Crit Care Med. 2000;161(4 Pt 1):1101–1108. doi:10.1164/ajrccm.161.4.9902063
   PubMed Web of Science ®Google Scholar
• Gray BA, Hyde RW, Hodges M, Yu PN. Alterations in lung volume and pulmonary function in relation to hemodynamic changes in acute myocardial infarction. Circulation. 1979;59(3):551–559. doi:10.1161/01.CIR.59.3.551
   PubMed Web of Science ®Google Scholar
• Kanetake R, Takamatsu K, Park K, Yokoyama A. Prevalence and risk factors for COPD in subjects with preserved ratio impaired spirometry. BMJ Open Respir Res. 2022;9(1). doi:10.1136/bmjresp-2022-001298
   PubMed Web of Science ®Google Scholar
• Young KA, Strand M, Ragland MF, et al. Pulmonary subtypes exhibit differential global initiative for chronic obstructive lung disease spirometry stage progression: the COPDGene(R) study. Chronic Obstr Pulm Dis. 2019;6(5):414–429. doi:10.15326/jcopdf.6.5.2019.0155
   PubMed Web of Science ®Google Scholar
• Young KA, Regan EA, Han MK, et al. Subtypes of COPD have unique distributions and differential risk of mortality. Chronic Obstr Pulm Dis. 2019;6(5):400–413. doi:10.15326/jcopdf.6.5.2019.0150
   PubMed Web of Science ®Google Scholar
• Wan ES, Balte P, Schwartz JE, et al. Association between preserved ratio impaired spirometry and clinical outcomes in US adults. J Am Med Assoc. 2021;326(22):2287–2298. doi:10.1001/jama.2021.20939
   PubMed Web of Science ®Google Scholar
• Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax. 2010;65(6):499–504. doi:10.1136/thx.2009.126052
   PubMed Web of Science ®Google Scholar
• Miura S, Iwamoto H, Omori K, et al. Preserved ratio impaired spirometry with or without restrictive spirometric abnormality. Sci Rep. 2023;13(1):2988. doi:10.1038/s41598-023-29922-0
   PubMed Web of Science ®Google Scholar
• Gold DR, Wang X, Wypij D, Speizer FE, Ware JH, Dockery DW. Effects of cigarette smoking on lung function in adolescent boys and girls. N Engl J Med. 1996;335(13):931–937. doi:10.1056/NEJM199609263351304
   PubMed Web of Science ®Google Scholar
• Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA. Combined impact of smoking and early-life exposures on adult lung function trajectories. Am J Respir Crit Care Med. 2017;196(8):1021–1030. doi:10.1164/rccm.201703-0506OC
   PubMed Web of Science ®Google Scholar
• Evans MD, Pryor WA. Cigarette smoking, emphysema, and damage to alpha 1-proteinase inhibitor. Am J Physiol. 1994;266(6 Pt 1):L593–L611. Erratum in: Am J Physiol. 1995;268(1 Pt 1):section L following table of contents. Erratum in: Am J Physiol. 1995;268(6 Pt 3). doi:10.1152/ajplung.1994.266.6.L593
   PubMed Web of Science ®Google Scholar
• Lugg ST, Scott A, Parekh D, Naidu B, Thickett DR. Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease. Thorax. 2022;77(1):94–101. doi:10.1136/thoraxjnl-2020-216296
   PubMed Web of Science ®Google Scholar
• Tang X, Lei J, Li W, et al. The relationship between BMI and lung function in populations with different characteristics: a cross-sectional study based on the enjoying breathing program in China. Int J Chron Obstruct Pulmon Dis. 2022;17:2677–2692. doi:10.2147/COPD.S378247
   PubMed Web of Science ®Google Scholar
• Mafort TT, Rufino R, Costa CH, Lopes AJ. Obesity: systemic and pulmonary complications, biochemical abnormalities, and impairment of lung function. Multidiscip Respir Med. 2016;11(1):28. doi:10.1186/s40248-016-0066-z
   PubMedGoogle Scholar
• Brazzale DJ, Pretto JJ, Schachter LM. Optimizing respiratory function assessments to elucidate the impact of obesity on respiratory health. Respirology. 2015;20(5):715–721. doi:10.1111/resp.12563
   PubMed Web of Science ®Google Scholar
• Grigsby MR, Siddharthan T, Pollard SL, et al. Low body mass index is associated with higher odds of COPD and lower lung function in low- and middle-income countries. COPD. 2019;16(1):58–65. doi:10.1080/15412555.2019.1589443
   PubMedGoogle Scholar
• Zhang Q, Qiu M, Lai K, Zhong N. Cough and environmental air pollution in China. Pulm Pharmacol Ther. 2015;35:132–136. doi:10.1016/j.pupt.2015.10.003
   PubMed Web of Science ®Google Scholar
• Jackson P, Siddharthan T. The global significance of PRISm: how data from low- and middle-income countries link physiology to inflammation. Eur Respir J. 2020;55(4):2000184. doi:10.1183/13993003.00184-2020
   PubMedGoogle Scholar
• Godfrey MS, Jankowich MD. The vital capacity is vital: epidemiology and clinical significance of the restrictive spirometry pattern. Chest. 2016;149(1):238–251. doi:10.1378/chest.15-1045
   PubMed Web of Science ®Google Scholar
• de Barros Mendes Lopes T, Groth EE, Veras M, et al. Pre- and postnatal exposure of mice to concentrated urban PM2.5 decreases the number of alveoli and leads to altered lung function at an early stage of life. Environ Pollut. 2018;241:511–520. doi:10.1016/j.envpol.2018.05.055
   PubMed Web of Science ®Google Scholar
• Hou D, Ge Y, Chen C, et al. Associations of long-term exposure to ambient fine particulate matter and nitrogen dioxide with lung function: a cross-sectional study in China. Environ Int. 2020;144:105977. doi:10.1016/j.envint.2020.105977
   PubMed Web of Science ®Google Scholar
• Miura S, Iwamoto H, Omori K, et al. Clinical characteristics of preserved ratio impaired spirometry in Japan. Respirology. 2021;26(Suppl 3):81–82.
   Google Scholar
• Raherison C, Girodet PO. Epidemiology of COPD. Eur Respir Rev. 2009;18(114):213–221. doi:10.1183/09059180.00003609
   PubMedGoogle Scholar
• Lopez-Campos JL, Tan W, Soriano JB. Global burden of COPD. Respirology. 2016;21(1):14–23. doi:10.1111/resp.12660
   PubMed Web of Science ®Google Scholar
• Ritchie AI, Wedzicha JA. Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations. Clin Chest Med. 2020;41(3):421–438.
   PubMed Web of Science ®Google Scholar
• Salvi S. Tobacco smoking and environmental risk factors for chronic obstructive pulmonary disease. Clin Chest Med. 2014;35(1):17–27. doi:10.1016/j.ccm.2013.09.011
   PubMed Web of Science ®Google Scholar
• Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary. Am J Respir Crit Care Med. 2017;195(5):557–582. doi:10.1164/rccm.201701-0218PP
   PubMed Web of Science ®Google Scholar
• He D, Sun Y, Gao M, et al. Different risks of mortality and longitudinal transition trajectories in new potential subtypes of the preserved ratio impaired spirometry: evidence from the English longitudinal study of aging. Front Med. 2021;8:755855. doi:10.3389/fmed.2021.755855
   Web of Science ®Google Scholar
• Lowe KE, Regan EA, Anzueto A, et al. COPDGene® 2019: redefining the diagnosis of chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2019;6(5):384–399. doi:10.15326/jcopdf.6.5.2019.0149
   PubMed Web of Science ®Google Scholar
• Fortis S, Corazalla EO, Jacobs DR, Kim HJ. Persistent empiric COPD diagnosis and treatment after pulmonary function test showed no obstruction. Respir Care. 2016;61(9):1192–1200. doi:10.4187/respcare.04647
   PubMed Web of Science ®Google Scholar
• Adibi A, Sadatsafavi M. Looking at the COPD spectrum through “PRISm”. Eur Respir J. 2020;55(1):1902217. doi:10.1183/13993003.02217-2019
   PubMed Web of Science ®Google Scholar
• Lu J, Ge H, Qi L, et al. Subtyping preserved ratio impaired spirometry (PRISm) by using quantitative HRCT imaging characteristics. Respir Res. 2022;23(1):309. doi:10.1186/s12931-022-02113-7
   PubMed Web of Science ®Google Scholar
• Serifoglu I, Ulubay G. The methods other than spirometry in the early diagnosis of COPD. Tuberk Toraks. 2019;67(1):63–70. doi:10.5578/tt.68162
   PubMed Web of Science ®Google Scholar
• Wei X, Ding Q, Yu N, et al. Imaging features of chronic bronchitis with preserved ratio and impaired spirometry (PRISm). Lung. 2018;196(6):649–658. doi:10.1007/s00408-018-0162-2
   PubMed Web of Science ®Google Scholar
• Wan ES, Hokanson JE, Murphy JR, et al. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med. 2011;184(1):57–63. doi:10.1164/rccm.201101-0021OC
   PubMed Web of Science ®Google Scholar
• Kim SS, Yagihashi K, Stinson DS, et al. Visual assessment of CT findings in smokers with nonobstructed spirometric abnormalities in the COPDGene® study. Chronic Obstr Pulm Dis. 2014;1(1):88–96. doi:10.15326/jcopdf.1.1.2013.0001#sthash.L0atdpjM.dpuf
   PubMedGoogle Scholar
• Fortis S, Comellas A, Kim V, et al. Low FVC/TLC in Preserved Ratio Impaired Spirometry (PRISm) is associated with features of and progression to obstructive lung disease. Sci Rep. 2020;10(1):5169. doi:10.1038/s41598-020-61932-0
   PubMed Web of Science ®Google Scholar
• Douillet D, Chouihed T, Bertoletti L, Roy PM. Pulmonary embolism and respiratory deterioration in chronic cardiopulmonary disease: a narrative review. Diagnostics. 2023;13(1):141. doi:10.3390/diagnostics13010141
   Web of Science ®Google Scholar
• Silvestre OM, Nadruz W, Querejeta Roca G, et al. Declining lung function and cardiovascular risk: the ARIC study. J Am Coll Cardiol. 2018;72(10):1109–1122. doi:10.1016/j.jacc.2018.06.049
   PubMed Web of Science ®Google Scholar
• Katta N, Loethen T, Lavie CJ, Alpert MA. Obesity and coronary heart disease: epidemiology, pathology, and coronary artery imaging. Curr Probl Cardiol. 2021;46(3):100655. doi:10.1016/j.cpcardiol.2020.100655
   PubMed Web of Science ®Google Scholar
• Shah N, Kelly AM, Cox N, Wong C, Soon K. Myocardial infarction in the “Young”: risk factors, presentation, management and prognosis. Heart Lung Circ. 2016;25(10):955–960. doi:10.1016/j.hlc.2016.04.015
   PubMed Web of Science ®Google Scholar
• Thomas PS, Cowen ER, Hulands G, Milledge JS. Respiratory function in the morbidly obese before and after weight loss. Thorax. 1989;44(5):382–386. doi:10.1136/thx.44.5.382
   PubMed Web of Science ®Google Scholar
• Talaminos Barroso A, Marquez Martin E, Roa Romero LM, Ortega Ruiz F. Factors affecting lung function: a review of the literature. Arch Bronconeumol. 2018;54(6):327–332. doi:10.1016/j.arbres.2018.01.030
   PubMed Web of Science ®Google Scholar
• Collins LC, Hoberty PD, Walker JF, Fletcher EC, Peiris AN. The effect of body fat distribution on pulmonary function tests. Chest. 1995;107(5):1298–1302. doi:10.1378/chest.107.5.1298
   PubMed Web of Science ®Google Scholar
• Lazarus R, Gore CJ, Booth M, Owen N. Effects of body composition and fat distribution on ventilatory function in adults. Am J Clin Nutr. 1998;68(1):35–41. doi:10.1093/ajcn/68.1.35
   PubMed Web of Science ®Google Scholar
• Ray CS, Sue DY, Bray G, Hansen JE, Wasserman K. Effects of obesity on respiratory function. Am Rev Respir Dis. 1983;128(3):501–506. doi:10.1164/arrd.1983.128.3.501
   PubMed Web of Science ®Google Scholar
• Carey IM, Cook DG, Strachan DP. The effects of adiposity and weight change on forced expiratory volume decline in a longitudinal study of adults. Int J Obes Relat Metab Disord. 1999;23(9):979–985. doi:10.1038/sj.ijo.0801029
   PubMed Web of Science ®Google Scholar
• Pankow W, Podszus T, Gutheil T, Penzel T, Peter J, Von Wichert P. Expiratory flow limitation and intrinsic positive end-expiratory pressure in obesity. J Appl Physiol. 1998;85(4):1236–1243. doi:10.1152/jappl.1998.85.4.1236
   PubMed Web of Science ®Google Scholar
• Mancuso P. Obesity and lung inflammation. J Appl Physiol. 2010;108(3):722–728. doi:10.1152/japplphysiol.00781.2009
   PubMed Web of Science ®Google Scholar
• Arismendi E, Bantula M, Perpina M, Picado C. Effects of obesity and asthma on lung function and airway dysanapsis in adults and children. J Clin Med. 2020;9(11):3762. doi:10.3390/jcm9113762
   PubMed Web of Science ®Google Scholar
• Gilmartin GS, Tamisier R, Curley M, Weiss JW. Ventilatory, hemodynamic, sympathetic nervous system, and vascular reactivity changes after recurrent nocturnal sustained hypoxia in humans. Am J Physiol Heart Circ Physiol. 2008;295(2):H778–H785. doi:10.1152/ajpheart.00653.2007
   PubMed Web of Science ®Google Scholar
• Calbet JA. Chronic hypoxia increases blood pressure and noradrenaline spillover in healthy humans. J Physiol. 2003;551(Pt 1):379–386. doi:10.1113/jphysiol.2003.045112
   PubMed Web of Science ®Google Scholar
• Mannino DM, McBurnie MA, Tan W, et al.; BOLD Collaborative Research Group. Restricted spirometry in the burden of lung disease study. Int J Tuberc Lung Dis. 2012;16(10):1405–1411.
   PubMed Web of Science ®Google Scholar
• Meghji J, Nadeau G, Davis KJ, et al. Noncommunicable lung disease in sub-Saharan Africa. A community-based cross-sectional study of Adults in Urban Malawi. Am J Respir Crit Care Med. 2016;194(1):67–76. doi:10.1164/rccm.201509-1807OC
   PubMed Web of Science ®Google Scholar
• Klein OL, Krishnan JA, Glick S, Smith LJ. Systematic review of the association between lung function and Type 2 diabetes mellitus. Diabet Med. 2010;27(9):977–987. doi:10.1111/j.1464-5491.2010.03073.x
   PubMed Web of Science ®Google Scholar
• Walter RE, Beiser A, Givelber RJ, O’Connor GT, Gottlieb DJ. Association between glycemic state and lung function: the Framingham Heart Study. Am J Respir Crit Care Med. 2003;167(6):911–916. doi:10.1164/rccm.2203022
   PubMed Web of Science ®Google Scholar
• Lawlor DA, Ebrahim S, Smith GD. Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women’s Heart and Health Study. Diabetologia. 2004;47(2):195–203. doi:10.1007/s00125-003-1310-6
   PubMed Web of Science ®Google Scholar
• Yeh F, Dixon AE, Marion S, et al. Obesity in adults is associated with reduced lung function in metabolic syndrome and diabetes: the Strong Heart Study. Diabetes Care. 2011;34(10):2306–2313. doi:10.2337/dc11-0682
   PubMed Web of Science ®Google Scholar
• Klein OL, Kalhan R, Williams MV, et al. Lung spirometry parameters and diffusion capacity are decreased in patients with Type 2 diabetes. Diabet Med. 2012;29(2):212–219. doi:10.1111/j.1464-5491.2011.03394.x
   PubMed Web of Science ®Google Scholar
• Zhu J, Zhao H, Chen D, Tse LA, Kinra S, Li Y. Genetic correlation and bidirectional causal association between Type 2 diabetes and pulmonary function. Front Endocrinol. 2021;12:777487. doi:10.3389/fendo.2021.777487
   PubMed Web of Science ®Google Scholar
• Hsia CC, Raskin P. Lung function changes related to diabetes mellitus. Diabetes Technol Ther. 2007;9(Suppl 1):S-73-S-82. doi:10.1089/dia.2007.0227
   PubMedGoogle Scholar
• Liu L, Feng Q, Wang Y, et al. Interaction of polycyclic aromatic hydrocarbon exposure and high-fasting plasma glucose on lung function decline in coke oven workers: a cross-lagged panel analysis. Environ Toxicol Pharmacol. 2022;90:103811. doi:10.1016/j.etap.2022.103811
   PubMed Web of Science ®Google Scholar
• Shin J, Toyoda S, Nishitani S, et al. SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1. Metabolism. 2022;133:155236. doi:10.1016/j.metabol.2022.155236
   PubMed Web of Science ®Google Scholar
• Hoffmann C, Gerber PA, Cavelti-Weder C, et al. Liver, NAFLD and COVID-19. Horm Metab Res. 2022;54(8):522–531. doi:10.1055/a-1834-9008
   PubMedGoogle Scholar
• Torres RM, Souza MDS, Coelho ACC, de Mello LM, Souza-Machado C, Leroyer C. Association between Asthma and Type 2 diabetes mellitus: mechanisms and impact on asthma control-A literature review. Can Respir J. 2021;2021:8830439. doi:10.1155/2021/8830439
   PubMed Web of Science ®Google Scholar
• Kotlyarov S, Bulgakov A. Lipid metabolism disorders in the comorbid course of nonalcoholic fatty liver disease and chronic obstructive pulmonary disease. Cells. 2021;10(11):2978. doi:10.3390/cells10112978
   PubMed Web of Science ®Google Scholar
• Margretardottir OB, Thorleifsson SJ, Gudmundsson G, et al. Hypertension, systemic inflammation and body weight in relation to lung function impairment-an epidemiological study. COPD. 2009;6(4):250–255. doi:10.1080/15412550903049157
   PubMedGoogle Scholar
• Enright PL, Kronmal RA, Smith VE, Gardin JM, Schenker MB, Manolio TA. Reduced vital capacity in elderly persons with hypertension, coronary heart disease, or left ventricular hypertrophy. The Cardiovascular Health Study. Chest. 1995;107(1):28–35. doi:10.1378/chest.107.1.28
   PubMed Web of Science ®Google Scholar
• Engström G, Hedblad B, Valind S, Janzon L. Increased incidence of myocardial infarction and stroke in hypertensive men with reduced lung function. J Hypertens. 2001;19(2):295–301. doi:10.1097/00004872-200102000-00017
   PubMed Web of Science ®Google Scholar
• Kannel WB, Hubert H, Lew EA. Vital capacity as a predictor of cardiovascular disease: the Framingham study. Am Heart J. 1983;105(2):311–315. doi:10.1016/0002-8703(83)90532-X
   PubMed Web of Science ®Google Scholar
• Wannamethee SG, Shaper AG, Ebrahim S. Respiratory function and risk of stroke. Stroke. 1995;26(11):2004–2010. doi:10.1161/01.STR.26.11.2004
   PubMed Web of Science ®Google Scholar
• Selby JV, Friedman GD, Quesenberry CP. Precursors of essential hypertension: pulmonary function, heart rate, uric acid, serum cholesterol, and other serum chemistries. Am J Epidemiol. 1990;131(6):1017–1027. doi:10.1093/oxfordjournals.aje.a115593
   PubMed Web of Science ®Google Scholar
• Wu Y, Vollmer WM, Buist AS, et al. Relationship between lung function and blood pressure in Chinese men and women of Beijing and Guangzhou. PRC-USA Cardiovascular and Cardiopulmonary Epidemiology Research Group. Int J Epidemiol. 1998;27(1):49–56. doi:10.1093/ije/27.1.49
   PubMed Web of Science ®Google Scholar
• Jankowich MD, Taveira T, Wu WC. Decreased lung function is associated with increased arterial stiffness as measured by peripheral pulse pressure: data from NHANES III. Am J Hypertens. 2010;23(6):614–619. doi:10.1038/ajh.2010.37
   PubMed Web of Science ®Google Scholar
• Doshan HD, Rosenthal RR, Brown R, Slutsky A, Applin WJ, Caruso FS. Celiprolol, atenolol and propranolol: a comparison of pulmonary effects in asthmatic patients. J Cardiovasc Pharmacol. 1986;8(Suppl 4):S105–S108.
   PubMedGoogle Scholar
• van Zyl AI, Jennings AA, Bateman ED, Opie LH. Comparison of respiratory effects of two cardioselective beta-blockers, celiprolol and atenolol, in asthmatics with mild to moderate hypertension. Chest. 1989;95(1):209–213. doi:10.1378/chest.95.1.209
   PubMed Web of Science ®Google Scholar
• Williams DM. Clinical pharmacology of corticosteroids. Respir Care. 2018;63(6):655–670. doi:10.4187/respcare.06314
   PubMed Web of Science ®Google Scholar
• Washko GR, Hunninghake GM, Fernandez IE, et al. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med. 2011;364(10):897–906. doi:10.1056/NEJMoa1007285
   PubMed Web of Science ®Google Scholar