Pharmacist-Managed Diabetes Programs: Improving Treatment Adherence and Patient Outcomes

References

• World Health Organization. Diabetes; 2021. Available from: https://www.who.int/news-room/fact-sheets/detail/diabetes. Accessed June 7, 2022.
   Google Scholar
• CDC. Cost-effectiveness of diabetes interventions; 2021. Available from: https://www.cdc.gov/chronicdisease/programs-impact/pop/diabetes.htm#:~:text=The%20High%20Cost%20of%20Diabeteshronic%20condition%20in%20our%20nation.&text=%241%20out%20of%20every%20%244aring%20for%20people%20with%20diabetes.&text=%24237%20billion%E2%80%A1(c)%20is,(c)%20on%20reduced%20productivity. Accessed February 9, 2022.
   Google Scholar
• Zhou X, Siegel KR, Ng BP, et al. Cost-effectiveness of diabetes prevention interventions targeting high-risk individuals and whole populations: a systematic review. Diabetes Care. 2020;43:1593–1616. doi:10.2337/dci20-0018
   Web of Science ®Google Scholar
• Healy AM, Shubrook JH, Schwartz FL, Cummings DM, Drake AJ, Tanenberg RJ. Endocrinologists’ opinions of diabetology as a primary care subspecialty. Clin Diabetes. 2018;36:168–173. doi:10.2337/cd17-0097
   Google Scholar
• Bodenheimer T, Sinsky C. From triple to quadruple AIM: care of the patient requires care of the provider. Ann Fam Med. 2014;12:573–576. doi:10.1370/afm.1713
   PubMed Web of Science ®Google Scholar
• American College of Clinical Pharmacy. Comprehensive medication management in team-based care. Available from: https://www.pcpcc.org/sites/default/files/event-attachments/CMM%20Brief.pdf. Accessed June 7, 2022.
   Google Scholar
• Norton MC, Haftman ME, Buzzard LN. Impact of physician-pharmacist collaboration on diabetes outcomes and health care use. J Am Board Fam Med. 2020;33:745–753. doi:10.3122/jabfm.2020.05.200044
   Web of Science ®Google Scholar
• Schultz JL, Horner KE, McDanel DL, et al. Comparing clinical outcomes of a pharmacist-managed diabetes clinic to usual physician-based care. J Pharm Pract. 2018;31:268–271. doi:10.1177/0897190017710522
   Web of Science ®Google Scholar
• Ragucci KR, Fermo JD, Wessell AM, Chumney EC. Effectiveness of pharmacist-administered diabetes mellitus education and management services. Pharmacotherapy. 2005;25:1809–1816. doi:10.1592/phco.2005.25.12.1809
   Web of Science ®Google Scholar
• Salvo MC, Brooks AM. Glycemic control and preventive care measures of indigent diabetes patients within a pharmacist-managed insulin titration program vs standard care. Ann Pharmacother. 2012;46:29–34. doi:10.1345/aph.1Q512
   Web of Science ®Google Scholar
• Rochester CD, Leon N, Dombrowski R, Haines ST. Collaborative drug therapy management for initiating and adjusting insulin therapy in patients with type 2 diabetes mellitus. Am J Health Syst Pharm. 2010;67:42–48. doi:10.2146/ajhp080706
   Web of Science ®Google Scholar
• Scott DM, Boyd ST, Stephan M, Augustine SC, Reardon TP. Outcomes of pharmacist-managed diabetes care services in a community health center. Am J Health Syst Pharm. 2006;63:2116–2122. doi:10.2146/ajhp060040
   PubMed Web of Science ®Google Scholar
• Wubben DP, Vivian EM. Effects of pharmacist outpatient interventions on adults with diabetes mellitus: a systematic review. Pharmacotherapy. 2008;28:421–436. doi:10.1592/phco.28.4.421
   PubMed Web of Science ®Google Scholar
• Ko JJ, Lu J, Rascati K, et al. Analysis of glycemic control of a pharmacist-led medication management program in patients with type 2 diabetes. J Manag Care Spec Pharm. 2016;22:32–37. doi:10.18553/jmcp.2016.22.1.32
   Web of Science ®Google Scholar
• Choe HM, Mitrovich S, Dubay D, Hayward RA, Krein SL, Vijan S. Proactive case management of high-risk patients with type 2 diabetes mellitus by a clinical pharmacist: a randomized controlled trial. Am J Manag Care. 2005;11:253–260.
   PubMed Web of Science ®Google Scholar
• Collier IA, Baker DM. Implementation of a pharmacist-supervised outpatient diabetes treatment clinic. Am J Health Syst Pharm. 2014;71:27–36. doi:10.2146/ajhp130200
   Web of Science ®Google Scholar
• Aneese NJ, Halalau A, Muench S, Shelden D, Fett J, Lauster C. Impact of a pharmacist-managed diabetes clinic on quality measures. Am J Manag Care. 2018;24:Sp116–Sp119.
   Google Scholar
• Farland MZ, Byrd DC, McFarland MS, et al. Pharmacist-physician collaboration for diabetes care: the diabetes initiative program. Ann Pharmacother. 2013;47:781–789. doi:10.1345/aph.1S079
   PubMed Web of Science ®Google Scholar
• Ray S, Lokken J, Whyte C, Baumann A, Oldani M. The impact of a pharmacist-driven, collaborative practice on diabetes management in an Urban underserved population: a mixed method assessment. J Interprof Care. 2020;34:27–35. doi:10.1080/13561820.2019.1633289
   PubMed Web of Science ®Google Scholar
• Chung N, Rascati K, Lopez D, Jokerst J, Garza A. Impact of a clinical pharmacy program on changes in hemoglobin A1c, diabetes-related hospitalizations, and diabetes-related emergency department visits for patients with diabetes in an underserved population. J Manag Care Spec Pharm. 2014;20:914–919.
   Web of Science ®Google Scholar
• McCord AD. Clinical impact of a pharmacist-managed diabetes mellitus drug therapy management service. Pharmacotherapy. 2006;26:248–253. doi:10.1592/phco.26.2.248
   PubMed Web of Science ®Google Scholar
• Benedict AW, Spence MM, Sie JL, et al. Evaluation of a pharmacist-managed diabetes program in a primary care setting within an integrated health care system. J Manag Care Spec Pharm. 2018;24:114–122. doi:10.18553/jmcp.2018.24.2.114
   Web of Science ®Google Scholar
• Padiyara RS, D’Souza JJ, Rihani RS. Clinical pharmacist intervention and the proportion of diabetes patients attaining prevention objectives in a multispecialty medical group. J Manag Care Pharm. 2011;17:456–462. doi:10.18553/jmcp.2011.17.6.456
   Web of Science ®Google Scholar
• Lewis J, Nguyen T, Althobaiti H, et al. Impact of an advanced practice pharmacist type 2 diabetes management program: a Pilot Study. Innov Pharm. 2019;10:20. doi:10.24926/iip.v10i4.2237
   Google Scholar
• Cowart K, Sando K. Pharmacist impact on treatment intensification and hemoglobin A(1C) in patients with type 2 diabetes mellitus at an academic health center. J Pharm Pract. 2019;32:648–654. doi:10.1177/0897190018776178
   Web of Science ®Google Scholar
• Anaya JP, Rivera JO, Lawson K, Garcia J, Luna J, Ortiz M. Evaluation of pharmacist-managed diabetes mellitus under a collaborative drug therapy agreement. Am J Health Syst Pharm. 2008;65:1841–1845. doi:10.2146/ajhp070568
   PubMed Web of Science ®Google Scholar
• Morello CM, Zadvorny EB, Cording MA, Suemoto RT, Skog J, Harari A. Development and clinical outcomes of pharmacist-managed diabetes care clinics. Am J Health Syst Pharm. 2006;63:1325–1331. doi:10.2146/ajhp050430
   Web of Science ®Google Scholar
• Sullivan J, Jett BP, Cradick M, Zuber J. Effect of clinical pharmacist intervention on hemoglobin A1C reduction in veteran patients with type 2 diabetes in a rural setting. Ann Pharmacother. 2016;50:1023–1027. doi:10.1177/1060028016663564
   PubMed Web of Science ®Google Scholar
• Pontefract BA, King BS, Gothard DM, King CA. Impact of pharmacist-led diabetes management in primary care clinics. Innov Pharm. 2018;9:1–8. doi:10.24926/iip.v9i2.985
   Google Scholar
• Sease JM, Franklin MA, Gerrald KR. Pharmacist management of patients with diabetes mellitus enrolled in a rural free clinic. Am J Health Syst Pharm. 2013;70:43–47. doi:10.2146/ajhp120221
   Web of Science ®Google Scholar
• Federal Register. Medicare Program; CY 2021 Payment Policies Under the Physician Fee Schedule and Other Changes to Part B Payment Policies. 2020. Available from: https://www.federalregister.gov/documents/2020/12/28/2020-26815/medicare-program-cy-2021-payment-policies-under-the-physician-fee-schedule-and-other-changes-to-part. Accessed Feb 4, 2022.
   Google Scholar
• Woodhouse AG, Orvin C, Rich C, Crosby J, Keedy CA. Diabetes outcomes before and during telehealth advancements surrounding COVID-19. J Am Pharm Assoc. 2022;62:214–217. doi:10.1016/j.japh.2021.09.011
   Google Scholar
• Niznik JD, He H, Kane-Gill SL. Impact of clinical pharmacist services delivered via telemedicine in the outpatient or ambulatory care setting: a systematic review. Res Social Adm Pharm. 2018;14:707–717. doi:10.1016/j.sapharm.2017.10.011
   Web of Science ®Google Scholar
• Hawes EM, Lambert E, Reid A, Tong G, Gwynne M. Implementation and evaluation of a pharmacist-led electronic visit program for diabetes and anticoagulation care in a patient-centered medical home. Am J Health Syst Pharm. 2018;75:901–910. doi:10.2146/ajhp170174
   Web of Science ®Google Scholar
• Cohen LB, Taveira TH, Wu WC, Pirraglia PA. Pharmacist-led telehealth disease management program for patients with diabetes and depression. J Telemed Telecare. 2020;26:294–302. doi:10.1177/1357633X18822575
   Web of Science ®Google Scholar
• Fantasia KL, Stockman MC, Ju Z, et al. Professional continuous glucose monitoring and endocrinology eConsult for adults with type 2 diabetes in primary care: results of a clinical pilot program. J Clin Transl Endocrinol. 2021;24:100254. doi:10.1016/j.jcte.2021.100254
   Google Scholar
• Ulrich H, Bowen M. The clinical utility of professional continuous glucose monitoring by pharmacists for patients with type 2 diabetes. J Am Pharm Assoc. 2003;2021(61):e76–e82.
   Google Scholar
• Shah M, Norwood CA, Farias S, Ibrahim S, Chong PH, Fogelfeld L. Diabetes transitional care from inpatient to outpatient setting: pharmacist discharge counseling. J Pharm Pract. 2013;26:120–124. doi:10.1177/0897190012451907
   Google Scholar
• Murphy JA, Schroeder MN, Ridner AT, Gregory ME, Whitner JB, Hackett SG. Impact of a pharmacy-initiated inpatient diabetes patient education program on 30-day readmission rates. J Pharm Pract. 2020;33:754–759. doi:10.1177/0897190019833217
   Web of Science ®Google Scholar
• Shi FH, Shen L, Yue J, et al. Intervention by clinical pharmacists can improve blood glucose fluctuation in patients with diabetes and acute myocardial infarction: a propensity score-matched analysis. Pharmacol Res Perspect. 2021;9:e00725. doi:10.1002/prp2.725
   Web of Science ®Google Scholar
• Shi FH, Shen L, Pan MM, et al. The successful rapid adjustment of blood glucose in a patient with acute coronary syndrome, renal insufficiency, and diabetes: a case report of management coordinated by clinical pharmacists and clinicians. Front Pharmacol. 2020;11:756. doi:10.3389/fphar.2020.00756
   PubMed Web of Science ®Google Scholar
• Sharif A, Hecking M, de Vries AP, et al. Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions. Am J Transplant. 2014;14:1992–2000. doi:10.1111/ajt.12850
   PubMed Web of Science ®Google Scholar
• Do V, Haakinson D, Belfort-DeAguiar R, Cohen E. Implementing a pharmacist-led transition of care model for posttransplant hyperglycemia. Am J Health Syst Pharm. 2021;78:1207–1215. doi:10.1093/ajhp/zxab151
   Web of Science ®Google Scholar
• Newland DM, Edwards AR, Hall RC, Maxwell PR. Positive impact of a pilot pharmacist-run diabetes pharmacotherapy clinic in solid-organ transplant recipients. Diabetes Spectr. 2018;31:167–176. doi:10.2337/ds17-0029
   Google Scholar
• The Lancet Diabetes & Endocrinology. Diabetes behind bars: challenging inadequate care in prisons. Lancet Diabetes Endocrinol. 2018;6:347. doi:10.1016/S2213-8587(18)30103-7
   Google Scholar
• Lin CH, Tran NT, Muradian IK, et al. Impact of a pharmacist-led diabetes clinic in a correctional setting. J Pharm Pract. 2021;34:596–599. doi:10.1177/0897190019888075
   Web of Science ®Google Scholar
• Batta RA, Kasabri V, Akour A, Hyassat D, Albsoul-Younes A. Impact of clinical pharmacists intervention on management of hyperglycemia in pregnancy in Jordan. Int J Clin Pharm. 2018;40:48–55. doi:10.1007/s11096-017-0550-3
   Web of Science ®Google Scholar
• Fazel MT, Bagalagel A, Lee JK, Martin JR, Slack MK. Impact of diabetes care by pharmacists as part of health care team in ambulatory settings: a systematic review and meta-analysis. Ann Pharmacother. 2017;51:890–907. doi:10.1177/1060028017711454
   PubMed Web of Science ®Google Scholar
• Shane-McWhorter L, McAdam-Marx C, Lenert L, et al. Pharmacist-provided diabetes management and education via a telemonitoring program. J Am Pharm Assoc. 2003;2015(55):516–526.
   Google Scholar
• Maxwell LG, McFarland MS, Baker JW, Cassidy RF. Evaluation of the impact of a pharmacist-led telehealth clinic on diabetes-related goals of therapy in a veteran population. Pharmacotherapy. 2016;36:348–356. doi:10.1002/phar.1719
   Web of Science ®Google Scholar
• Hui RL, Chang CC, Niu F, et al. Evaluation of a pharmacist-managed antidiabetic deprescribing program in an integrated health care system. J Manag Care Spec Pharm. 2019;25:927–934. doi:10.18553/jmcp.2019.25.8.927
   PubMed Web of Science ®Google Scholar
• van Eikenhorst L, Taxis K, van Dijk L, de Gier H. Pharmacist-led self-management interventions to improve diabetes outcomes. A systematic literature review and meta-analysis. Front Pharmacol. 2017;8. doi:10.3389/fphar.2017.00891
   Web of Science ®Google Scholar
• Pousinho S, Morgado M, Plácido AI, Roque F, Falcão A, Alves G. Clinical pharmacists´ interventions in the management of type 2 diabetes mellitus: a systematic review. Pharm Pract. 2020;18:2000.
   Web of Science ®Google Scholar
• Iqbal MZ, Khan AH, Iqbal MS, Syed Sulaiman SA. A review of pharmacist-led interventions on diabetes outcomes: an observational analysis to explore diabetes care opportunities for pharmacists. J Pharm Bioallied Sci. 2019;11:299–309. doi:10.4103/jpbs.JPBS_138_19
   Web of Science ®Google Scholar
• Al-Omar LT, Anderson SL, Cizmic AD, Vlasimsky TB. Implementation of a pharmacist-led diabetes management protocol. Am Health Drug Benefits. 2019;12:14–20.
   PubMed Web of Science ®Google Scholar
• Abdelaziz TA, Abdulraheem MA, Badi SA, et al. Knowledge, attitude and practice of Sudanese pharmacist with regard to management of diabetes during Ramadan: a cross-sectional survey. Diabetes Metab Syndr. 2019;13:122–126. doi:10.1016/j.dsx.2018.07.019
   Web of Science ®Google Scholar
• Risøy AJ, Skeide Kjome RL, Svensberg K, Råheim M, Sølvik U. Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies - A focus-group study. Res Social Adm Pharm. 2021;17:1259–1266. doi:10.1016/j.sapharm.2020.09.011
   PubMed Web of Science ®Google Scholar
• Katangwe T, Family H, Sokhi J, Al-Jabr H, Kirkdale CL, Twigg MJ. The community pharmacy setting for diabetes prevention: views and perceptions of stakeholders. PLoS One. 2019;14:e0219686. doi:10.1371/journal.pone.0219686
   Web of Science ®Google Scholar
• Pinelli NR, Clark LM, Carrington AC, Carrington JL, Malinzak L, Patel A. Pharmacist managed diabetes and cardiovascular risk reduction clinic in kidney transplant recipients: bridging the gap in care transition. Diabetes Res Clin Pract. 2014;106:e64–e67. doi:10.1016/j.diabres.2014.09.034
   Web of Science ®Google Scholar
• Wagner EH, Sandhu N, Newton KM, McCulloch DK, Ramsey SD, Grothaus LC. Effect of improved glycemic control on health care costs and utilization. JAMA. 2001;285:182–189. doi:10.1001/jama.285.2.182
   PubMed Web of Science ®Google Scholar
• Hirsch JD, Bounthavong M, Arjmand A, et al. Estimated cost-effectiveness, cost benefit, and risk reduction associated with an endocrinologist-pharmacist diabetes intense medical management “Tune-Up” clinic. J Manag Care Spec Pharm. 2017;23:318–326. doi:10.18553/jmcp.2017.23.3.318
   PubMed Web of Science ®Google Scholar
• Juarez D, Goo R, Tokumaru S, Sentell T, Davis J, Mau M. Association between sustained glycated hemoglobin control and healthcare costs. Am J Pharm Benefits. 2013;5:59–64.
   Google Scholar
• Rodriguez de Bittner M, Chirikov VV, Breunig IM, Zaghab RW, Shaya FT. Clinical effectiveness and cost savings in diabetes care, supported by pharmacist counselling. J Am Pharm Assoc. 2017;57(1):102–8.e4. doi:10.1016/j.japh.2016.08.010
   Google Scholar
• Stanton-Robinson C, Al-Jumaili AA, Jackson A, Catney C, Veach S, Witry MJ. Evaluation of community pharmacist-provided telephone interventions to improve adherence to hypertension and diabetes medications. J Am Pharm Assoc. 2003;2018(58):S120–S124.
   Google Scholar
• Odegard PS, Carpinito G, Christensen DB. Medication adherence program: adherence challenges and interventions in type 2 diabetes. J Am Pharm Assoc. 2003;2013(53):267–272.
   Google Scholar
• Association of American Medical Colleges. AAMC Report Reinforces Mounting Physician Shortage. 2021. Available from: https://www.aamc.org/news-insights/press-releases/aamc-report-reinforces-mounting-physician-shortage. Accessed Feb 4, 2022.
   Google Scholar